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The map label for this gene is yycF [H]

Identifier: 86609993

GI number: 86609993

Start: 2664997

End: 2665737

Strand: Direct

Name: yycF [H]

Synonym: CYB_2561

Alternate gene names: 86609993

Gene position: 2664997-2665737 (Clockwise)

Preceding gene: 86609992

Following gene: 86609996

Centisome position: 87.47

GC content: 60.73

Gene sequence:

>741_bases
GTGGAAGCACAGCGTAAGGAACGGATTCTGGTGGTCGATGATGAGGCCAGCATTCGACGCATCTTGGAAACCCGTCTGTC
CATGATTGGATACGACGTGGTCACAGCTTCGGACGGCGAGGAGGCGCTGGAGGTTTTCCACAAGCAGGATCCCGACCTGG
TGGTGCTGGATGTGATGATGCCGAAGCTGGATGGCTATGGGGTCTGCCAGGAGCTGCGCAAAGAATCGGACATCCCCATC
ATCATGCTGACGGCGCTGGGAGATGTAGCCGACCGTATCACAGGGCTGGAGCTGGGGGCAGACGACTATGTGGTCAAGCC
CTTTTCGCCCAAGGAGCTGGAAGCTCGCATTCGGTCGGTGTTGCGCCGGGTGGCGCGGTCGGCCCACGATGGGATCCCCA
GTTCCGGGGTGATTCAAGTGGGGGACATCCGCATCGATACCAACAAGCGGCAGGTCTACAAACGGGACGAGCGCATTCGC
CTGACGGGGATGGAGTTTAGTCTGCTGGAGCTGCTGGTCAGTCGGTCGGGGGAGCCTTTTTCCCGCTCCGAGATTTTGCA
AGAGGTGTGGGGCTATACCCCGGAGCGCCATGTGGATACGCGGGTGGTGGATGTCCACATCTCGCGGCTGCGGGCCAAGC
TGGAGGATGACCCCAGCAACCCAGAGCTGATCCTGACGGCCCGAGGCACCGGCTATCTGTTTCAGCGCATCGTTCAGGGG
GAGGAACAGGCACGGTCTTGA

Upstream 100 bases:

>100_bases
AGGTTCCTGTATCCGCCCAACTCAAGTTAGCGCCCACCTCAGTTCTTTTTCAGATTTCTCTTTTACCGAGTACCGTTAGA
AGTTCAGGAGTTGCAGCACC

Downstream 100 bases:

>100_bases
GAGGGGATCCCTCGCAACCTCTCTTCAAGAGCGGCCTGCACCCGCCTCAACACGCCAACCCAGTCTCCCGGTGTGTTTTG
TCGAAACAAGCGCATCACCC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTASDGEEALEVFHKQDPDLVVLDVMMPKLDGYGVCQELRKESDIPI
IMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVARSAHDGIPSSGVIQVGDIRIDTNKRQVYKRDERIR
LTGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVQG
EEQARS

Sequences:

>Translated_246_residues
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTASDGEEALEVFHKQDPDLVVLDVMMPKLDGYGVCQELRKESDIPI
IMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVARSAHDGIPSSGVIQVGDIRIDTNKRQVYKRDERIR
LTGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVQG
EEQARS
>Mature_246_residues
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTASDGEEALEVFHKQDPDLVVLDVMMPKLDGYGVCQELRKESDIPI
IMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVARSAHDGIPSSGVIQVGDIRIDTNKRQVYKRDERIR
LTGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVQG
EEQARS

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=42.7350427350427, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.8695652173913, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=41.4096916299559, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=38.8646288209607, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=35.6828193832599, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=37.8260869565217, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=40.948275862069, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=38.6266094420601, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.4978165938865, Blast_Score=134, Evalue=5e-33,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=32.3144104803493, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=34.5132743362832, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=240, Percent_Identity=35.4166666666667, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.0434782608696, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=31.0924369747899, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1788550, Length=147, Percent_Identity=34.6938775510204, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=37.719298245614, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=101, Percent_Identity=34.6534653465347, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=34.3137254901961, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI145693157, Length=120, Percent_Identity=36.6666666666667, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788191, Length=127, Percent_Identity=31.496062992126, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788713, Length=124, Percent_Identity=37.0967741935484, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=32.258064516129, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788192, Length=107, Percent_Identity=37.3831775700935, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27885; Mature: 27885

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTASDGEEALEVFHKQDPDLVVLDVMM
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEEEHH
PKLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSV
CCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHH
LRRVARSAHDGIPSSGVIQVGDIRIDTNKRQVYKRDERIRLTGMEFSLLELLVSRSGEPF
HHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCC
SRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVQG
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHCC
EEQARS
HHHHCC
>Mature Secondary Structure
MEAQRKERILVVDDEASIRRILETRLSMIGYDVVTASDGEEALEVFHKQDPDLVVLDVMM
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEEEHH
PKLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSV
CCCCCCHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCEECCCCEEECCCCHHHHHHHHHHH
LRRVARSAHDGIPSSGVIQVGDIRIDTNKRQVYKRDERIRLTGMEFSLLELLVSRSGEPF
HHHHHHHHHCCCCCCCEEEEEEEEEECCHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCC
SRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEDDPSNPELILTARGTGYLFQRIVQG
CHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHCC
EEQARS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]