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The map label for this gene is dmpD [H]

Identifier: 86609738

GI number: 86609738

Start: 2402264

End: 2403088

Strand: Direct

Name: dmpD [H]

Synonym: CYB_2297

Alternate gene names: 86609738

Gene position: 2402264-2403088 (Clockwise)

Preceding gene: 86609737

Following gene: 86609741

Centisome position: 78.85

GC content: 59.76

Gene sequence:

>825_bases
GTGAAATTGGAAGGGTTGAACATCGCAGGGGCAGAGTCCTGCTGGGCTGCCTATCGAGACTGGGGAAAAGGGATCCCACT
GCTGTTTCTGCATGGCTTTATGGCCACTCACGCCAACTGGTGGCCGCTGATGCAAGGGTTGGGAGACGAATATCGCTGCA
TTGCCTTAGATTTGCTGGGGTTCGGGCAGTCTGGCCAACCGGCCTTGCGCTACGACATCGCTGCAGAAGTGGAGTTTGTG
CGCGGATTTGTCCAAACGCTGGGCCTACCTGCTCCGGTTTTGGTGGGCCATTCCTTTGGGGGATGGGTGGCAGCGGCCTA
TGCAGTACGGTATCCGCTGAGGGGATTGGTCTTGTTGGCTCCTGCCGGGATCCGCGACGACGGCTTTGTGAGACGCTACA
ACCATTTGCGGCCCTTGCTTTGGGAAAGCGCTTGGGTAGATTGGTTGCTGCGGGCGATCACCCCCTTGGCCCGCTGGTGG
CATTGGGAAGACCAACTGGCCCAGCTCTTGTGGTTGCGCGGATCCCTGCGCCAACAGCCAGTCGCTCGGCAATTTCTTCG
ACAACGTCTGCGCCCGCAAGCTGCCGTCGATACGGTTGAACGTTATCTCCAACACATTCAGGCCCCCACACTGGTGATCG
CCGCCGAACAGGACGACACCATTCCCCTCTGGCACTGCCAAACCTATGCCGAAGGGATCCCTGGGGCTCAGCTCAAGATC
CTGGCCGGGGCCGGCCACGCCATCCCTGCCTTGCATGGGGAACAGGTGCTGCCCCTAATTCGGGAATTTCTCGACACAGC
CCTTTCCGCACAATGCGGGCTTTGA

Upstream 100 bases:

>100_bases
CCCCAAGCCGATGACCAGGCAAACGCTGTTGGAACGACTCCCCCTGGCCAAGCGCTTGGCGGAGTTACAGGCCCGCGTTC
AAGAGATCCCGCTGCACAGG

Downstream 100 bases:

>100_bases
GCTGGGGCTGTAGCGTATGGCCGAGAGAGGAATGCCGCTTGCCAGATGGCGATGCCCGATAGGCGACGGAGCGCCGCCCA
AGGGGAACGCCTGACCCTAA

Product: alpha/beta fold family hydrolase

Products: NA

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKLEGLNIAGAESCWAAYRDWGKGIPLLFLHGFMATHANWWPLMQGLGDEYRCIALDLLGFGQSGQPALRYDIAAEVEFV
RGFVQTLGLPAPVLVGHSFGGWVAAAYAVRYPLRGLVLLAPAGIRDDGFVRRYNHLRPLLWESAWVDWLLRAITPLARWW
HWEDQLAQLLWLRGSLRQQPVARQFLRQRLRPQAAVDTVERYLQHIQAPTLVIAAEQDDTIPLWHCQTYAEGIPGAQLKI
LAGAGHAIPALHGEQVLPLIREFLDTALSAQCGL

Sequences:

>Translated_274_residues
MKLEGLNIAGAESCWAAYRDWGKGIPLLFLHGFMATHANWWPLMQGLGDEYRCIALDLLGFGQSGQPALRYDIAAEVEFV
RGFVQTLGLPAPVLVGHSFGGWVAAAYAVRYPLRGLVLLAPAGIRDDGFVRRYNHLRPLLWESAWVDWLLRAITPLARWW
HWEDQLAQLLWLRGSLRQQPVARQFLRQRLRPQAAVDTVERYLQHIQAPTLVIAAEQDDTIPLWHCQTYAEGIPGAQLKI
LAGAGHAIPALHGEQVLPLIREFLDTALSAQCGL
>Mature_274_residues
MKLEGLNIAGAESCWAAYRDWGKGIPLLFLHGFMATHANWWPLMQGLGDEYRCIALDLLGFGQSGQPALRYDIAAEVEFV
RGFVQTLGLPAPVLVGHSFGGWVAAAYAVRYPLRGLVLLAPAGIRDDGFVRRYNHLRPLLWESAWVDWLLRAITPLARWW
HWEDQLAQLLWLRGSLRQQPVARQFLRQRLRPQAAVDTVERYLQHIQAPTLVIAAEQDDTIPLWHCQTYAEGIPGAQLKI
LAGAGHAIPALHGEQVLPLIREFLDTALSAQCGL

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI50658087, Length=105, Percent_Identity=38.0952380952381, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17558492, Length=140, Percent_Identity=32.8571428571429, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32566936, Length=140, Percent_Identity=32.8571428571429, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586387, Length=163, Percent_Identity=28.8343558282209, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586391, Length=163, Percent_Identity=28.8343558282209, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586389, Length=163, Percent_Identity=28.8343558282209, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24586385, Length=163, Percent_Identity=28.8343558282209, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 30707; Mature: 30707

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEGLNIAGAESCWAAYRDWGKGIPLLFLHGFMATHANWWPLMQGLGDEYRCIALDLLG
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECC
FGQSGQPALRYDIAAEVEFVRGFVQTLGLPAPVLVGHSFGGWVAAAYAVRYPLRGLVLLA
CCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCHHEECCCCHHHHHHHHHHHHCCCCEEEEE
PAGIRDDGFVRRYNHLRPLLWESAWVDWLLRAITPLARWWHWEDQLAQLLWLRGSLRQQP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCH
VARQFLRQRLRPQAAVDTVERYLQHIQAPTLVIAAEQDDTIPLWHCQTYAEGIPGAQLKI
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHCCCCCCEEEE
LAGAGHAIPALHGEQVLPLIREFLDTALSAQCGL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLEGLNIAGAESCWAAYRDWGKGIPLLFLHGFMATHANWWPLMQGLGDEYRCIALDLLG
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECC
FGQSGQPALRYDIAAEVEFVRGFVQTLGLPAPVLVGHSFGGWVAAAYAVRYPLRGLVLLA
CCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCHHEECCCCHHHHHHHHHHHHCCCCEEEEE
PAGIRDDGFVRRYNHLRPLLWESAWVDWLLRAITPLARWWHWEDQLAQLLWLRGSLRQQP
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCH
VARQFLRQRLRPQAAVDTVERYLQHIQAPTLVIAAEQDDTIPLWHCQTYAEGIPGAQLKI
HHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHCCCCCCEEEE
LAGAGHAIPALHGEQVLPLIREFLDTALSAQCGL
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]