Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 86609703

GI number: 86609703

Start: 2363788

End: 2365941

Strand: Reverse

Name: htpX [H]

Synonym: CYB_2261

Alternate gene names: 86609703

Gene position: 2365941-2363788 (Counterclockwise)

Preceding gene: 86609704

Following gene: 86609698

Centisome position: 77.66

GC content: 62.3

Gene sequence:

>2154_bases
ATGATCCCCGATGCCGTCCAGGCGGGCAAGGAAGCCCTGCGGCAGGGCCGCCTTCAAGAGGCCATCCAACTTTTTGAAGG
CTACCTGGCCCAATCCCGTCAGCAGGACAAAGCATTAGGGATCCCGGCAGACTCATCTGACGGCGAAGCCCTGGAAGCCC
AAATGAACCTGGTGCGGGCCTACCACCAGTTGGGCCAGACGGAGAAGGCACGGTCCCTCTGCCTAGAGCTGCTGCAACAC
CCCAACCCCCAGGCGCAAGGCTGGGCCAAGAAGATCTTGCTTCGCCTGCCCACTGCAACAGAGTCCCTGGCTGCTCCGTC
CGCCAAACCTGTCGAACCGCGTTCTGCTCCCCCAGAGGAGCCGTCTCCTGGAGCGGGATCCCTGTCCACCCGTCAACGGG
CCGCCCAACTGGGTATGAAGATCCCCCTGCCGGAGCGGGCCGGCCCCCTGCATTGGGCCAAGTGGGGATCCCTGGGGGTG
GGCATTGTCTTCCTTTGGTGGCTGAGCTTTGTGTTGGTAGGCAGCCATCTGGATTTTGGCCGGCTGAGTTTTCCGCGGCA
GCTTTGGTTTTTGCAGGGGTTGCTGCCCTGGCTGCGCAATGGCCTGCGGTGGTTGGTGGCCGGCAGCCTGGCGGTCAACT
TTGGAGTAGGCCTTCTCTTTTTTGCCCCCTGGCTGATGGATCAGCTCCACCAACGGCTGCACAAGTTGCGTTGGGCCAGG
CTTGGCGAAATCGAACGCTACAGCCCCGAAACGGCGCGCCTGCTGCAGCGCATCTGTGCCCAAAACCAGCTAAAACAGCC
CCGACTGGGGGTGATCCCGGATGCTGGGCCGCTGGCCTTTGTTTACGGCACTTTTTCTGATGGCTGCCGCATTGTGGTCA
CCCAAGCCCTGTTGCAGCAGCTTTCTGAGGATGAGATTGCCGCCGTCTACGCCCAGGCCCTGGGGCGAATTGTTAATGGA
GATATCCTGGTCATGACCCTGCTGGGATCCCCGATTCAACTGGTTTACCTGGCCCTAGAGCAGGTGAGCCAACTGGGAAG
CAAACGGCGGGATCTCATCGGGCATGTGGCCCCGCTGCTCTACCTCATCTACACGGTGCTCTCCTACCCGCTGTTTTTCC
TCTCCCGCCTGGGCACCTACCATGCCGACCATTTTGCTGTAGAGGCGACTGGCAACCCGAACGGGCTGATTGCTGCTCTG
CTCAAATCGGCTGCTGGCCTGCAAGAGGCCCACAAAAACGACCGCCGACCTTCCTCGCTGTTGCACTGCACCCGCCTGTT
CAGCTTTTTGGACTTCAAAACCATCGCCGCTGCCAGTGCTGCCGCCCGCCTCCAGGATCCCTCCCAAGCTGGCCAAGTCT
TTCTTTGGGATCAAATCAACCCTTGGGCCCGCTGGATGCAGGTCAATTCCAGCCATCCGCTGCCGGGGCACCGCTTCAAG
GTCTTGGCGGGATATGGAGAGCGGCTGCGCCTCCTGCCGGAGCTGAGCCTGGGATCCGGGTCCAAATTGGATGTGGCCCG
CCTGCAAAGCCGGTTTTGGCTGGATCTGGCCATCTACGCAGCCGAAGTGGTCGGGATCCTCATTGGCTGGCTGGTGGGGC
TGATCCTCTACCTGCTGCTGCAAAACCGTCTCGATCCCAAGGTGATCGCGGCAGCAGCGGTGGTGGGCTACGGGGTGGGC
TTGTGGGCCAAAGCGGGATTGATGTACGGGGGATCCCTGCCGGCAAGGCCGACGGATGTGCTCAGCTTGCTGGCGGATCC
CGACGCGGATCCCCGCCGCGGACAATGGGTGGAGCTGGAGGGGGAGTTGGTGGGACTGGGCCCCTCCGGCTATCAACTGG
GGGCAGAGCTGAAGCTGCAAGAGGCCACAGGGCTGATCCCGGTGCGCTTTACTTCCCCTTTGGGGCCGGTGGGCAATGTC
TTTTCCGGCCTGAAGCGGATCCGCGCCCTGGTGGGCCGGCGCGTCAAAGTGGTGGGCTGGTTCCGCCGCGGCAATACTGC
TTGGGTGGATCTGGCCTACGTCCAGGTGGGATCCAATAAGCTGCACAGCCGACCGCGCCTTTGGCTGGTTGTGTTCGGCT
TGGGAGTCATCCTGCTGGGGATTTGGGGGGCGTTCTATTTCCCCAACTTGGCCTCTTACCTGCGGCGGTGGTGA

Upstream 100 bases:

>100_bases
GGGATCCGGTCTCTCAGGGTTGGATCCCTGAGTAAGCTGGGGGAGCAGATGGATCCAACCGATCTCCAGAAGCAGACCCT
ACCAGGCAAGGAGCAAGCCG

Downstream 100 bases:

>100_bases
GCCAGGCTCTCTTCCAGTTGGCTGAGAAAACTAGCGGCGAGAGGGCGTTAACTGTGCCTTGCGCAGGCGCACCGACTGGG
GCGTGATCTCCACCAGCTCA

Product: peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 717; Mature: 717

Protein sequence:

>717_residues
MIPDAVQAGKEALRQGRLQEAIQLFEGYLAQSRQQDKALGIPADSSDGEALEAQMNLVRAYHQLGQTEKARSLCLELLQH
PNPQAQGWAKKILLRLPTATESLAAPSAKPVEPRSAPPEEPSPGAGSLSTRQRAAQLGMKIPLPERAGPLHWAKWGSLGV
GIVFLWWLSFVLVGSHLDFGRLSFPRQLWFLQGLLPWLRNGLRWLVAGSLAVNFGVGLLFFAPWLMDQLHQRLHKLRWAR
LGEIERYSPETARLLQRICAQNQLKQPRLGVIPDAGPLAFVYGTFSDGCRIVVTQALLQQLSEDEIAAVYAQALGRIVNG
DILVMTLLGSPIQLVYLALEQVSQLGSKRRDLIGHVAPLLYLIYTVLSYPLFFLSRLGTYHADHFAVEATGNPNGLIAAL
LKSAAGLQEAHKNDRRPSSLLHCTRLFSFLDFKTIAAASAAARLQDPSQAGQVFLWDQINPWARWMQVNSSHPLPGHRFK
VLAGYGERLRLLPELSLGSGSKLDVARLQSRFWLDLAIYAAEVVGILIGWLVGLILYLLLQNRLDPKVIAAAAVVGYGVG
LWAKAGLMYGGSLPARPTDVLSLLADPDADPRRGQWVELEGELVGLGPSGYQLGAELKLQEATGLIPVRFTSPLGPVGNV
FSGLKRIRALVGRRVKVVGWFRRGNTAWVDLAYVQVGSNKLHSRPRLWLVVFGLGVILLGIWGAFYFPNLASYLRRW

Sequences:

>Translated_717_residues
MIPDAVQAGKEALRQGRLQEAIQLFEGYLAQSRQQDKALGIPADSSDGEALEAQMNLVRAYHQLGQTEKARSLCLELLQH
PNPQAQGWAKKILLRLPTATESLAAPSAKPVEPRSAPPEEPSPGAGSLSTRQRAAQLGMKIPLPERAGPLHWAKWGSLGV
GIVFLWWLSFVLVGSHLDFGRLSFPRQLWFLQGLLPWLRNGLRWLVAGSLAVNFGVGLLFFAPWLMDQLHQRLHKLRWAR
LGEIERYSPETARLLQRICAQNQLKQPRLGVIPDAGPLAFVYGTFSDGCRIVVTQALLQQLSEDEIAAVYAQALGRIVNG
DILVMTLLGSPIQLVYLALEQVSQLGSKRRDLIGHVAPLLYLIYTVLSYPLFFLSRLGTYHADHFAVEATGNPNGLIAAL
LKSAAGLQEAHKNDRRPSSLLHCTRLFSFLDFKTIAAASAAARLQDPSQAGQVFLWDQINPWARWMQVNSSHPLPGHRFK
VLAGYGERLRLLPELSLGSGSKLDVARLQSRFWLDLAIYAAEVVGILIGWLVGLILYLLLQNRLDPKVIAAAAVVGYGVG
LWAKAGLMYGGSLPARPTDVLSLLADPDADPRRGQWVELEGELVGLGPSGYQLGAELKLQEATGLIPVRFTSPLGPVGNV
FSGLKRIRALVGRRVKVVGWFRRGNTAWVDLAYVQVGSNKLHSRPRLWLVVFGLGVILLGIWGAFYFPNLASYLRRW
>Mature_717_residues
MIPDAVQAGKEALRQGRLQEAIQLFEGYLAQSRQQDKALGIPADSSDGEALEAQMNLVRAYHQLGQTEKARSLCLELLQH
PNPQAQGWAKKILLRLPTATESLAAPSAKPVEPRSAPPEEPSPGAGSLSTRQRAAQLGMKIPLPERAGPLHWAKWGSLGV
GIVFLWWLSFVLVGSHLDFGRLSFPRQLWFLQGLLPWLRNGLRWLVAGSLAVNFGVGLLFFAPWLMDQLHQRLHKLRWAR
LGEIERYSPETARLLQRICAQNQLKQPRLGVIPDAGPLAFVYGTFSDGCRIVVTQALLQQLSEDEIAAVYAQALGRIVNG
DILVMTLLGSPIQLVYLALEQVSQLGSKRRDLIGHVAPLLYLIYTVLSYPLFFLSRLGTYHADHFAVEATGNPNGLIAAL
LKSAAGLQEAHKNDRRPSSLLHCTRLFSFLDFKTIAAASAAARLQDPSQAGQVFLWDQINPWARWMQVNSSHPLPGHRFK
VLAGYGERLRLLPELSLGSGSKLDVARLQSRFWLDLAIYAAEVVGILIGWLVGLILYLLLQNRLDPKVIAAAAVVGYGVG
LWAKAGLMYGGSLPARPTDVLSLLADPDADPRRGQWVELEGELVGLGPSGYQLGAELKLQEATGLIPVRFTSPLGPVGNV
FSGLKRIRALVGRRVKVVGWFRRGNTAWVDLAYVQVGSNKLHSRPRLWLVVFGLGVILLGIWGAFYFPNLASYLRRW

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 79005; Mature: 79005

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPDAVQAGKEALRQGRLQEAIQLFEGYLAQSRQQDKALGIPADSSDGEALEAQMNLVRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
YHQLGQTEKARSLCLELLQHPNPQAQGWAKKILLRLPTATESLAAPSAKPVEPRSAPPEE
HHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCC
PSPGAGSLSTRQRAAQLGMKIPLPERAGPLHWAKWGSLGVGIVFLWWLSFVLVGSHLDFG
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
RLSFPRQLWFLQGLLPWLRNGLRWLVAGSLAVNFGVGLLFFAPWLMDQLHQRLHKLRWAR
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEIERYSPETARLLQRICAQNQLKQPRLGVIPDAGPLAFVYGTFSDGCRIVVTQALLQQ
HCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
LSEDEIAAVYAQALGRIVNGDILVMTLLGSPIQLVYLALEQVSQLGSKRRDLIGHVAPLL
HCHHHHHHHHHHHHHHHHCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLIYTVLSYPLFFLSRLGTYHADHFAVEATGNPNGLIAALLKSAAGLQEAHKNDRRPSSL
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LHCTRLFSFLDFKTIAAASAAARLQDPSQAGQVFLWDQINPWARWMQVNSSHPLPGHRFK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCHHHHHHCCCCCCCCCCCCEE
VLAGYGERLRLLPELSLGSGSKLDVARLQSRFWLDLAIYAAEVVGILIGWLVGLILYLLL
EEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNRLDPKVIAAAAVVGYGVGLWAKAGLMYGGSLPARPTDVLSLLADPDADPRRGQWVELE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEC
GELVGLGPSGYQLGAELKLQEATGLIPVRFTSPLGPVGNVFSGLKRIRALVGRRVKVVGW
CEEEEECCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
FRRGNTAWVDLAYVQVGSNKLHSRPRLWLVVFGLGVILLGIWGAFYFPNLASYLRRW
EECCCEEEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIPDAVQAGKEALRQGRLQEAIQLFEGYLAQSRQQDKALGIPADSSDGEALEAQMNLVRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
YHQLGQTEKARSLCLELLQHPNPQAQGWAKKILLRLPTATESLAAPSAKPVEPRSAPPEE
HHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCC
PSPGAGSLSTRQRAAQLGMKIPLPERAGPLHWAKWGSLGVGIVFLWWLSFVLVGSHLDFG
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCC
RLSFPRQLWFLQGLLPWLRNGLRWLVAGSLAVNFGVGLLFFAPWLMDQLHQRLHKLRWAR
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEIERYSPETARLLQRICAQNQLKQPRLGVIPDAGPLAFVYGTFSDGCRIVVTQALLQQ
HCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHH
LSEDEIAAVYAQALGRIVNGDILVMTLLGSPIQLVYLALEQVSQLGSKRRDLIGHVAPLL
HCHHHHHHHHHHHHHHHHCCCEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLIYTVLSYPLFFLSRLGTYHADHFAVEATGNPNGLIAALLKSAAGLQEAHKNDRRPSSL
HHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LHCTRLFSFLDFKTIAAASAAARLQDPSQAGQVFLWDQINPWARWMQVNSSHPLPGHRFK
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCHHHHHHCCCCCCCCCCCCEE
VLAGYGERLRLLPELSLGSGSKLDVARLQSRFWLDLAIYAAEVVGILIGWLVGLILYLLL
EEECCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNRLDPKVIAAAAVVGYGVGLWAKAGLMYGGSLPARPTDVLSLLADPDADPRRGQWVELE
HCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEC
GELVGLGPSGYQLGAELKLQEATGLIPVRFTSPLGPVGNVFSGLKRIRALVGRRVKVVGW
CEEEEECCCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
FRRGNTAWVDLAYVQVGSNKLHSRPRLWLVVFGLGVILLGIWGAFYFPNLASYLRRW
EECCCEEEEEEEEEEECCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA