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The map label for this gene is hemA [H]

Identifier: 86609700

GI number: 86609700

Start: 2360255

End: 2361550

Strand: Direct

Name: hemA [H]

Synonym: CYB_2258

Alternate gene names: 86609700

Gene position: 2360255-2361550 (Clockwise)

Preceding gene: 86609699

Following gene: 86609701

Centisome position: 77.47

GC content: 60.42

Gene sequence:

>1296_bases
ATGTTTATCGCGGTTGTCGGTCTTAGCCATCGCACAGCTCCCGTAGAGATTCGGGAGCGCCTCAGCATCGCGGAGGCGGA
GGTGGGAGAGACGATCCAGCAGCTTCGCACCCACCCCCACATTGAGGAGGCTGCGATCCTCAGCACCTGTAACCGGCTGG
AGGTCTACATCGTCACCTCAGAAATGGAGAGTGGTGTCCGGCAGACGATGCAGTTCTTGGCTGAGCTGAAAGGGATCCCC
TTGCCCCAACTGCGTCCGCACCTGTTTACCCTTCTTTACCAAGATGCCGTAACCCACCTGATGCGGGTGGCTGCCGGGCT
AGATAGCTTGGTGCTGGGAGAAGGGCAGATCCTCTCGCAGGTGAAAAAAGCCCAGCAACTGGGCCAAGCCTGCAACGGCA
TGGATCGCATCCTCAATCGCCTCTTTAAGGCGGCCATTACCGCCGGCAAACGCGTCCGTACCGAAACGGAGATCGGCACC
GGCGCCATGTCCATCAGCTCGGCAGCGGTGGAGTTGGCTCTGCAAGAGCAGGGATCCCTCTCTCAGGGCAAGGTTACCGT
GGTGGGGGCGGGGAGAATGGCCCGTCTGTTGGTGCAGCACCTGTTGGCCAAGGGGGCAGTCGATATCACGGTGGTCAACC
GCTCCCTGGAGCGAGCCGAAGCCCTGGCCAAGCAATTTGAGCAGCCGATCCAGGTGCTGCCTTGGGAGTCGCTGCTGAAC
AGTGTGGCCGAGTCCAACTTGGTCTTCACCAGCACCGGTGCCACCCAGCCGATCCTGAACTACCAGCAACTGGCAGGGGT
GCTGCAGCCGGATCAGCCGCTGTTGTTGGTGGATATCTCTGTGCCCCGCAACATCGATCCCGATGTGGAAAAGCTGAAGG
GGGTACAGGTGTTCAATGTGGATCACCTCTCCCGCATCGTGGAAGAAAACCGCGCCCAACGGCAAAAGCTGGCTCTGGCT
GCCGAAGCCCTGGTGGAAGAGGAGGTGGATCAATTCATGGAGTGGTGGCGTTCTCTGGAGACGGTGCCCACCATTTCCAG
CCTGCGCCACAAGGTGGAGTCCATCCGCGAGCAGGAGATGGAAAAAGCTCTCTCCCGCCTGGGCAAGGACTTTGCCGAGA
AGCACCTGGAGGTGATCGACGCCTTGACCCGCGGCATCGTCAACAAGATCCTGCACGACCCGATGGTGCAACTGCGGGCC
AAACGGGATATTGAGGCGCGGCGGGCAGCCATGCGGATCTTGCAGGAACTGTTCAACCTGGATCCGGTGGTGTTTCAAGC
CCAGCAGGAGCGCTAG

Upstream 100 bases:

>100_bases
CGGTCACAGCTCTTGCTTTCTCTCTGAAACAATATTTGCTTTTGTTCAGAGTTTTTGTTTTTAATAACTTTTGCTGTTGC
TGTACAGACGACGGAGAGGC

Downstream 100 bases:

>100_bases
GGATCCCTTGGCGAAGAGCGCATGACTTGAAGAATTGTAACAGCTCTCCCATCTGGGGTGGAGGGCACCCCTTAGGATAC
AAAGCGTAAGCCACAGGATC

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFIAVVGLSHRTAPVEIRERLSIAEAEVGETIQQLRTHPHIEEAAILSTCNRLEVYIVTSEMESGVRQTMQFLAELKGIP
LPQLRPHLFTLLYQDAVTHLMRVAAGLDSLVLGEGQILSQVKKAQQLGQACNGMDRILNRLFKAAITAGKRVRTETEIGT
GAMSISSAAVELALQEQGSLSQGKVTVVGAGRMARLLVQHLLAKGAVDITVVNRSLERAEALAKQFEQPIQVLPWESLLN
SVAESNLVFTSTGATQPILNYQQLAGVLQPDQPLLLVDISVPRNIDPDVEKLKGVQVFNVDHLSRIVEENRAQRQKLALA
AEALVEEEVDQFMEWWRSLETVPTISSLRHKVESIREQEMEKALSRLGKDFAEKHLEVIDALTRGIVNKILHDPMVQLRA
KRDIEARRAAMRILQELFNLDPVVFQAQQER

Sequences:

>Translated_431_residues
MFIAVVGLSHRTAPVEIRERLSIAEAEVGETIQQLRTHPHIEEAAILSTCNRLEVYIVTSEMESGVRQTMQFLAELKGIP
LPQLRPHLFTLLYQDAVTHLMRVAAGLDSLVLGEGQILSQVKKAQQLGQACNGMDRILNRLFKAAITAGKRVRTETEIGT
GAMSISSAAVELALQEQGSLSQGKVTVVGAGRMARLLVQHLLAKGAVDITVVNRSLERAEALAKQFEQPIQVLPWESLLN
SVAESNLVFTSTGATQPILNYQQLAGVLQPDQPLLLVDISVPRNIDPDVEKLKGVQVFNVDHLSRIVEENRAQRQKLALA
AEALVEEEVDQFMEWWRSLETVPTISSLRHKVESIREQEMEKALSRLGKDFAEKHLEVIDALTRGIVNKILHDPMVQLRA
KRDIEARRAAMRILQELFNLDPVVFQAQQER
>Mature_431_residues
MFIAVVGLSHRTAPVEIRERLSIAEAEVGETIQQLRTHPHIEEAAILSTCNRLEVYIVTSEMESGVRQTMQFLAELKGIP
LPQLRPHLFTLLYQDAVTHLMRVAAGLDSLVLGEGQILSQVKKAQQLGQACNGMDRILNRLFKAAITAGKRVRTETEIGT
GAMSISSAAVELALQEQGSLSQGKVTVVGAGRMARLLVQHLLAKGAVDITVVNRSLERAEALAKQFEQPIQVLPWESLLN
SVAESNLVFTSTGATQPILNYQQLAGVLQPDQPLLLVDISVPRNIDPDVEKLKGVQVFNVDHLSRIVEENRAQRQKLALA
AEALVEEEVDQFMEWWRSLETVPTISSLRHKVESIREQEMEKALSRLGKDFAEKHLEVIDALTRGIVNKILHDPMVQLRA
KRDIEARRAAMRILQELFNLDPVVFQAQQER

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=426, Percent_Identity=35.6807511737089, Blast_Score=234, Evalue=9e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015896
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF00745 GlutR_dimer; PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 48027; Mature: 48027

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIAVVGLSHRTAPVEIRERLSIAEAEVGETIQQLRTHPHIEEAAILSTCNRLEVYIVTS
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEH
EMESGVRQTMQFLAELKGIPLPQLRPHLFTLLYQDAVTHLMRVAAGLDSLVLGEGQILSQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHH
VKKAQQLGQACNGMDRILNRLFKAAITAGKRVRTETEIGTGAMSISSAAVELALQEQGSL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHHHHHHCCCC
SQGKVTVVGAGRMARLLVQHLLAKGAVDITVVNRSLERAEALAKQFEQPIQVLPWESLLN
CCCCEEEEECCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCHHHCCCHHHHHH
SVAESNLVFTSTGATQPILNYQQLAGVLQPDQPLLLVDISVPRNIDPDVEKLKGVQVFNV
HHHHCCEEEEECCCCCHHCCHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHCCCEEECH
DHLSRIVEENRAQRQKLALAAEALVEEEVDQFMEWWRSLETVPTISSLRHKVESIREQEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EKALSRLGKDFAEKHLEVIDALTRGIVNKILHDPMVQLRAKRDIEARRAAMRILQELFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPVVFQAQQER
CHHHHCCCCCC
>Mature Secondary Structure
MFIAVVGLSHRTAPVEIRERLSIAEAEVGETIQQLRTHPHIEEAAILSTCNRLEVYIVTS
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEEH
EMESGVRQTMQFLAELKGIPLPQLRPHLFTLLYQDAVTHLMRVAAGLDSLVLGEGQILSQ
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHH
VKKAQQLGQACNGMDRILNRLFKAAITAGKRVRTETEIGTGAMSISSAAVELALQEQGSL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHCCHHHCCCCHHHHHHHHHHHHHHHCCCC
SQGKVTVVGAGRMARLLVQHLLAKGAVDITVVNRSLERAEALAKQFEQPIQVLPWESLLN
CCCCEEEEECCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHCHHHCCCHHHHHH
SVAESNLVFTSTGATQPILNYQQLAGVLQPDQPLLLVDISVPRNIDPDVEKLKGVQVFNV
HHHHCCEEEEECCCCCHHCCHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHCCCEEECH
DHLSRIVEENRAQRQKLALAAEALVEEEVDQFMEWWRSLETVPTISSLRHKVESIREQEM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EKALSRLGKDFAEKHLEVIDALTRGIVNKILHDPMVQLRAKRDIEARRAAMRILQELFNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPVVFQAQQER
CHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA