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The map label for this gene is moaE [H]

Identifier: 86609649

GI number: 86609649

Start: 2309838

End: 2310320

Strand: Reverse

Name: moaE [H]

Synonym: CYB_2203

Alternate gene names: 86609649

Gene position: 2310320-2309838 (Counterclockwise)

Preceding gene: 86609650

Following gene: 86609646

Centisome position: 75.83

GC content: 58.18

Gene sequence:

>483_bases
TTGAGCTTATTATTGACTAGAGTCATGCTCCTGACCGTCCTGAAGACTTCCTTCCAGATTACCCTGGCTCCCCTGTCCAT
CGACCGTGTCCACCAAGAGGCCTACCATCCGGGCAATGGGGCCGTGGTGGTGATGAGCGGTACCGTTCGAGACAACACCA
ATGGCCGCCCTGTCGATTACCTGGAATACCAAGCCTATGAGCCCATGGCCCTGAAGGTCTTCGCCGATATTGCCCGACAA
ATTCAGCAGCGCTGGCCAGATGCCAACAGTGTGGTCATCCACCACCGCATCGGCAAGCTGCGCATTGGCGAGATCAGCGT
CTTGGTGGCGGTGGGCACCCCTCATCGGGCCGAAGGGTTTGCTGCCTGCCAATTTGCCATCGACACCCTCAAGCACAACG
CCCCCATCTGGAAAAAAGAATACTGGCGAGATGGCACCAGCGCCTGGGTGAGCCTTGGCGCTTGCGAGCTCTCTTCGGCA
TAG

Upstream 100 bases:

>100_bases
TGCTTTGCTTTGGCTACCATGTTGGCAGACTCGAAAGTAAACAGAAAGATCAACTGGTAGTAATCCGTACTGAACATATT
ATACATTATTTTCAGTATAG

Downstream 100 bases:

>100_bases
ATCCCCCTACACCATACCCACTTGCTCAGCCAAACCCAATTGCTGGCGGGCTGTTTGGCAATCTTGCTGAATTTGCTGAA
TCAAATCTGCCACCGTGGGA

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSLLLTRVMLLTVLKTSFQITLAPLSIDRVHQEAYHPGNGAVVVMSGTVRDNTNGRPVDYLEYQAYEPMALKVFADIARQ
IQQRWPDANSVVIHHRIGKLRIGEISVLVAVGTPHRAEGFAACQFAIDTLKHNAPIWKKEYWRDGTSAWVSLGACELSSA

Sequences:

>Translated_160_residues
MSLLLTRVMLLTVLKTSFQITLAPLSIDRVHQEAYHPGNGAVVVMSGTVRDNTNGRPVDYLEYQAYEPMALKVFADIARQ
IQQRWPDANSVVIHHRIGKLRIGEISVLVAVGTPHRAEGFAACQFAIDTLKHNAPIWKKEYWRDGTSAWVSLGACELSSA
>Mature_159_residues
SLLLTRVMLLTVLKTSFQITLAPLSIDRVHQEAYHPGNGAVVVMSGTVRDNTNGRPVDYLEYQAYEPMALKVFADIARQI
QQRWPDANSVVIHHRIGKLRIGEISVLVAVGTPHRAEGFAACQFAIDTLKHNAPIWKKEYWRDGTSAWVSLGACELSSA

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=141, Percent_Identity=39.0070921985816, Blast_Score=107, Evalue=6e-24,
Organism=Escherichia coli, GI1787003, Length=102, Percent_Identity=42.156862745098, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17509279, Length=133, Percent_Identity=36.0902255639098, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21356259, Length=127, Percent_Identity=43.3070866141732, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 17785; Mature: 17654

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLLTRVMLLTVLKTSFQITLAPLSIDRVHQEAYHPGNGAVVVMSGTVRDNTNGRPVDY
CHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCEECCCCCCCCCE
LEYQAYEPMALKVFADIARQIQQRWPDANSVVIHHRIGKLRIGEISVLVAVGTPHRAEGF
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCEEEEEEECCCCCCCCH
AACQFAIDTLKHNAPIWKKEYWRDGTSAWVSLGACELSSA
HHHHHHHHHHHCCCCCCHHHHHCCCCHHHEEECCEECCCC
>Mature Secondary Structure 
SLLLTRVMLLTVLKTSFQITLAPLSIDRVHQEAYHPGNGAVVVMSGTVRDNTNGRPVDY
HHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCEECCCCCCCCCE
LEYQAYEPMALKVFADIARQIQQRWPDANSVVIHHRIGKLRIGEISVLVAVGTPHRAEGF
EEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEECCEEEEEEECCCCCCCCH
AACQFAIDTLKHNAPIWKKEYWRDGTSAWVSLGACELSSA
HHHHHHHHHHHCCCCCCHHHHHCCCCHHHEEECCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]