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The map label for this gene is galE [H]

Identifier: 86609640

GI number: 86609640

Start: 2302757

End: 2303761

Strand: Direct

Name: galE [H]

Synonym: CYB_2194

Alternate gene names: 86609640

Gene position: 2302757-2303761 (Clockwise)

Preceding gene: 86609639

Following gene: 86609641

Centisome position: 75.58

GC content: 59.7

Gene sequence:

>1005_bases
ATGCGTCTCCTGGTTACCGGCGGGGCGGGCTACATCGGCAGCCACACCTGCAAAGCTCTGGCGGCCTCTGGCCATCTGCC
CATCACTTACGACAACTTGGTTTACGGGCACCCCTGGGCAGTTCGCTGGGGGCCGTTGGAGATTGGGGATCTCGCCGACC
GCCAGCGGCTTGATCAAGTCATCCAACACTATCGCCCGGAAGGGGTGATCCACTTTGCTGCCTATGCCTATGTGGGCGAG
TCGGTCAAGGATCCCGGCAAATACTACCGCAACAATGTGGCCGGATCCCTGAGTTTGTTGGAGGCCATGCGGGATCACGG
GATCCCTTACATAGTGTTCTCCAGCACCTGTGCCACTTATGGGGTGCCAGAGCGGATTCCTATTCCCGAAAGTCATCCGC
AACGTCCCATCAACCCCTACGGCCAGAGCAAGCTGATGGTGGAGCAGATCTTGCAAGATTTCCAGGTTGCCCACGGGATC
CGATCCATTAGCCTGCGCTACTTCAATGCCGCCGGAGCCGATCCCGATGGCGAAATTGGGGAGGCCCACGACCCGGAAAC
CCACCTGATCCCCTTGGTGTTGGAGGTCGCCGGCGGCCAACGTCTTCACATCACGGTTTTTGGAGATGACTACGATACCC
CCGATGGCACCTGTATCCGAGACTACATCCATGTCACCGACCTGGCGCAAGCCCACGTGTTGGCAATAGAAGCGCTGGCC
TCTGGCCGGCCCATACAACCAGCCTACAACCTGGGCAATGGCCGAGGCTTTTCCGTCAAAGAGGTCATTGCCACCGCAGC
AGCCGTGACCGGAAAGCGGATCCCGGTGCAAATGGGAGCACGTCGACCTGGGGATCCCCCGCGCTTGGTGGGCGATGCCG
GTGCCATCTTTCGGGATCTCAACTGGAAACCTCTCTACACCGACCTGGCCGAGATCATTCAAACTGCCTGGCGCTGGCAC
CAGAAGCGACCCTATTTCGGCAAATCTAGGCCCCCGTTGAGCTAG

Upstream 100 bases:

>100_bases
GTGTGGAGGTCATGTACGCCGCCAAAGAAGCTTTTGGAGCTTGAAGGGATCCCGTCGGCAGCCTTTATCCTGGGTGGGAT
CTTCCATCTGACGTTTGCCT

Downstream 100 bases:

>100_bases
GAGCGTCTAGCTTGGCGGGCGATAGGATAGGGAGGAACCGCTTGGTTAACCACTGCCCCGCATGGACGATAAGACCACAC
CCGATACCCTCGCGGTTGTC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRLLVTGGAGYIGSHTCKALAASGHLPITYDNLVYGHPWAVRWGPLEIGDLADRQRLDQVIQHYRPEGVIHFAAYAYVGE
SVKDPGKYYRNNVAGSLSLLEAMRDHGIPYIVFSSTCATYGVPERIPIPESHPQRPINPYGQSKLMVEQILQDFQVAHGI
RSISLRYFNAAGADPDGEIGEAHDPETHLIPLVLEVAGGQRLHITVFGDDYDTPDGTCIRDYIHVTDLAQAHVLAIEALA
SGRPIQPAYNLGNGRGFSVKEVIATAAAVTGKRIPVQMGARRPGDPPRLVGDAGAIFRDLNWKPLYTDLAEIIQTAWRWH
QKRPYFGKSRPPLS

Sequences:

>Translated_334_residues
MRLLVTGGAGYIGSHTCKALAASGHLPITYDNLVYGHPWAVRWGPLEIGDLADRQRLDQVIQHYRPEGVIHFAAYAYVGE
SVKDPGKYYRNNVAGSLSLLEAMRDHGIPYIVFSSTCATYGVPERIPIPESHPQRPINPYGQSKLMVEQILQDFQVAHGI
RSISLRYFNAAGADPDGEIGEAHDPETHLIPLVLEVAGGQRLHITVFGDDYDTPDGTCIRDYIHVTDLAQAHVLAIEALA
SGRPIQPAYNLGNGRGFSVKEVIATAAAVTGKRIPVQMGARRPGDPPRLVGDAGAIFRDLNWKPLYTDLAEIIQTAWRWH
QKRPYFGKSRPPLS
>Mature_334_residues
MRLLVTGGAGYIGSHTCKALAASGHLPITYDNLVYGHPWAVRWGPLEIGDLADRQRLDQVIQHYRPEGVIHFAAYAYVGE
SVKDPGKYYRNNVAGSLSLLEAMRDHGIPYIVFSSTCATYGVPERIPIPESHPQRPINPYGQSKLMVEQILQDFQVAHGI
RSISLRYFNAAGADPDGEIGEAHDPETHLIPLVLEVAGGQRLHITVFGDDYDTPDGTCIRDYIHVTDLAQAHVLAIEALA
SGRPIQPAYNLGNGRGFSVKEVIATAAAVTGKRIPVQMGARRPGDPPRLVGDAGAIFRDLNWKPLYTDLAEIIQTAWRWH
QKRPYFGKSRPPLS

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=39.1812865497076, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=39.1812865497076, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=39.1812865497076, Blast_Score=234, Evalue=7e-62,
Organism=Homo sapiens, GI7657641, Length=279, Percent_Identity=25.8064516129032, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI42516563, Length=327, Percent_Identity=25.0764525993884, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1786974, Length=337, Percent_Identity=44.5103857566766, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI48994969, Length=339, Percent_Identity=26.5486725663717, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788353, Length=344, Percent_Identity=26.7441860465116, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790049, Length=266, Percent_Identity=28.1954887218045, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=38.8405797101449, Blast_Score=221, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=38.6167146974063, Blast_Score=220, Evalue=6e-58,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=38.4839650145773, Blast_Score=222, Evalue=6e-59,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=36.9186046511628, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=24.2718446601942, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36757; Mature: 36757

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVTGGAGYIGSHTCKALAASGHLPITYDNLVYGHPWAVRWGPLEIGDLADRQRLDQV
CEEEEECCCCCCCHHHHHHHHCCCCCCEEECCEEECCCCEEEECCCCCCHHHHHHHHHHH
IQHYRPEGVIHFAAYAYVGESVKDPGKYYRNNVAGSLSLLEAMRDHGIPYIVFSSTCATY
HHHHCCCCEEEEHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHC
GVPERIPIPESHPQRPINPYGQSKLMVEQILQDFQVAHGIRSISLRYFNAAGADPDGEIG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCC
EAHDPETHLIPLVLEVAGGQRLHITVFGDDYDTPDGTCIRDYIHVTDLAQAHVLAIEALA
CCCCCCCHHEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGRPIQPAYNLGNGRGFSVKEVIATAAAVTGKRIPVQMGARRPGDPPRLVGDAGAIFRDL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCEECCCHHHHHCC
NWKPLYTDLAEIIQTAWRWHQKRPYFGKSRPPLS
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRLLVTGGAGYIGSHTCKALAASGHLPITYDNLVYGHPWAVRWGPLEIGDLADRQRLDQV
CEEEEECCCCCCCHHHHHHHHCCCCCCEEECCEEECCCCEEEECCCCCCHHHHHHHHHHH
IQHYRPEGVIHFAAYAYVGESVKDPGKYYRNNVAGSLSLLEAMRDHGIPYIVFSSTCATY
HHHHCCCCEEEEHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHC
GVPERIPIPESHPQRPINPYGQSKLMVEQILQDFQVAHGIRSISLRYFNAAGADPDGEIG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCC
EAHDPETHLIPLVLEVAGGQRLHITVFGDDYDTPDGTCIRDYIHVTDLAQAHVLAIEALA
CCCCCCCHHEEEEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SGRPIQPAYNLGNGRGFSVKEVIATAAAVTGKRIPVQMGARRPGDPPRLVGDAGAIFRDL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCEECCCHHHHHCC
NWKPLYTDLAEIIQTAWRWHQKRPYFGKSRPPLS
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9236769 [H]