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The map label for this gene is hldE [H]

Identifier: 86609608

GI number: 86609608

Start: 2262301

End: 2263200

Strand: Direct

Name: hldE [H]

Synonym: CYB_2162

Alternate gene names: 86609608

Gene position: 2262301-2263200 (Clockwise)

Preceding gene: 86609607

Following gene: 86609611

Centisome position: 74.25

GC content: 63.0

Gene sequence:

>900_bases
TTGGGGGAGGTGCTTTTCGACTGCTTCCCCACCGAGGTTGTGCTGGGTGGGGCGGCTTTGAATGTGGCTTGGAACCTCAA
GGGGCTGGGATCCGATCCCCTCTTGCTCAGTCGTGTTGGCCAAGACGAGGCCGCCAGAGAGCTGCTGGGGGCCTTGCGAC
GGCAGGGGCTGCGCCTGGAGGGTCTGCAGCAGGATTCTGTTCACCCCACCGGCAAGGTTCAAGTAACCCTGGATGAGCAA
GGGATCCCCACCTTCGCCATCTTGCCCGACCAAGCCTACGACTACATCCAGTTGGATATCGGGGCTCTGCAAGCTCTCCA
GCCCAGCCTGCTCTACCGGGGCAGCTTGGCAGCCCGCCGGGAGGCAGCCCATCGCCATTTTCAAGAGGGGATCCCCGCTT
TGGGCTGTCCCGTGTTTCTGGATCTCAACCTGCGGGATCCCTGGTGGCATCCAGACGCCATCCGGGAGATGCTGCGCACC
TGCACTTGGCTGAAGCTGAACCAGGCAGAGCTGGAGCAAGTGGCCCAACTGGAAGGGATCCCTCCTGGAGACCTGCTGGA
GCAAGGACAGATCCTCCAGGCTCATCTGAACCTGAAAGGTCTATTTCTGACCTTGGGAGCGGCAGGCGCGCTGCTGATCA
CCCCTACTCAGATCCATCGGGCCGACCCAGTGCCCGCGCCTCAGCTGGTGGATACAGTGGGGGCGGGAGATGCATTTAGC
GCCGTGGCCATCCTGGGGCTGTTGCGGGGATGGCCGGAGGCGATTCTGGTGCAACGGGCCGTGCAATTTGCGGCGGCCAT
CTGCGGGATCCCGGGGGGAGCGCCTGCGGATCCGGAGTTTTACCGGCCCTTCTGGCAGGCATGGGAGATCCAGGAGATCC
AGAGGCCAAGGGTTCAATGA

Upstream 100 bases:

>100_bases
CTCGACACTGATCCTACCGGTACAGCACGGGGCTCCTGCGATTTCTAGCTGAGTGCTCAAGATGGATCCCTCTCATGTGC
CCCTGGGTTTGCCGCTCATC

Downstream 100 bases:

>100_bases
AACTGGCGCAGGTGAAACTGGGCGTAGCGACCCCCTTTGCCCAGCAATTCTCGGTGATTTCCCTGCTCCAGCAATTGCCC
CTGCTCCAAGACGAAAATGC

Product: PfkB family kinase

Products: ADP; D-fructose 6-phosphate

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MGEVLFDCFPTEVVLGGAALNVAWNLKGLGSDPLLLSRVGQDEAARELLGALRRQGLRLEGLQQDSVHPTGKVQVTLDEQ
GIPTFAILPDQAYDYIQLDIGALQALQPSLLYRGSLAARREAAHRHFQEGIPALGCPVFLDLNLRDPWWHPDAIREMLRT
CTWLKLNQAELEQVAQLEGIPPGDLLEQGQILQAHLNLKGLFLTLGAAGALLITPTQIHRADPVPAPQLVDTVGAGDAFS
AVAILGLLRGWPEAILVQRAVQFAAAICGIPGGAPADPEFYRPFWQAWEIQEIQRPRVQ

Sequences:

>Translated_299_residues
MGEVLFDCFPTEVVLGGAALNVAWNLKGLGSDPLLLSRVGQDEAARELLGALRRQGLRLEGLQQDSVHPTGKVQVTLDEQ
GIPTFAILPDQAYDYIQLDIGALQALQPSLLYRGSLAARREAAHRHFQEGIPALGCPVFLDLNLRDPWWHPDAIREMLRT
CTWLKLNQAELEQVAQLEGIPPGDLLEQGQILQAHLNLKGLFLTLGAAGALLITPTQIHRADPVPAPQLVDTVGAGDAFS
AVAILGLLRGWPEAILVQRAVQFAAAICGIPGGAPADPEFYRPFWQAWEIQEIQRPRVQ
>Mature_298_residues
GEVLFDCFPTEVVLGGAALNVAWNLKGLGSDPLLLSRVGQDEAARELLGALRRQGLRLEGLQQDSVHPTGKVQVTLDEQG
IPTFAILPDQAYDYIQLDIGALQALQPSLLYRGSLAARREAAHRHFQEGIPALGCPVFLDLNLRDPWWHPDAIREMLRTC
TWLKLNQAELEQVAQLEGIPPGDLLEQGQILQAHLNLKGLFLTLGAAGALLITPTQIHRADPVPAPQLVDTVGAGDAFSA
VAILGLLRGWPEAILVQRAVQFAAAICGIPGGAPADPEFYRPFWQAWEIQEIQRPRVQ

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.1.4

Molecular weight: Translated: 32606; Mature: 32475

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVLFDCFPTEVVLGGAALNVAWNLKGLGSDPLLLSRVGQDEAARELLGALRRQGLRLE
CCCCCHHCCCHHHEECCEEEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCC
GLQQDSVHPTGKVQVTLDEQGIPTFAILPDQAYDYIQLDIGALQALQPSLLYRGSLAARR
CCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEHHHHHHHCHHHHHHCCHHHHH
EAAHRHFQEGIPALGCPVFLDLNLRDPWWHPDAIREMLRTCTWLKLNQAELEQVAQLEGI
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCEEECHHHHHHHHHHCCC
PPGDLLEQGQILQAHLNLKGLFLTLGAAGALLITPTQIHRADPVPAPQLVDTVGAGDAFS
CCHHHHHCCCCEEECCCCCEEEEEECCCCEEEECCHHHHCCCCCCCHHHHHHCCCCHHHH
AVAILGLLRGWPEAILVQRAVQFAAAICGIPGGAPADPEFYRPFWQAWEIQEIQRPRVQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GEVLFDCFPTEVVLGGAALNVAWNLKGLGSDPLLLSRVGQDEAARELLGALRRQGLRLE
CCCCHHCCCHHHEECCEEEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCC
GLQQDSVHPTGKVQVTLDEQGIPTFAILPDQAYDYIQLDIGALQALQPSLLYRGSLAARR
CCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEEEHHHHHHHCHHHHHHCCHHHHH
EAAHRHFQEGIPALGCPVFLDLNLRDPWWHPDAIREMLRTCTWLKLNQAELEQVAQLEGI
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCEEECHHHHHHHHHHCCC
PPGDLLEQGQILQAHLNLKGLFLTLGAAGALLITPTQIHRADPVPAPQLVDTVGAGDAFS
CCHHHHHCCCCEEECCCCCEEEEEECCCCEEEECCHHHHCCCCCCCHHHHHHCCCCHHHH
AVAILGLLRGWPEAILVQRAVQFAAAICGIPGGAPADPEFYRPFWQAWEIQEIQRPRVQ
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; D-fructose

Specific reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA