| Definition | Synechococcus sp. JA-2-3B'a(2-13), complete genome. |
|---|---|
| Accession | NC_007776 |
| Length | 3,046,682 |
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The map label for this gene is murF [H]
Identifier: 86609487
GI number: 86609487
Start: 2140819
End: 2142156
Strand: Direct
Name: murF [H]
Synonym: CYB_2039
Alternate gene names: 86609487
Gene position: 2140819-2142156 (Clockwise)
Preceding gene: 86609486
Following gene: 86609488
Centisome position: 70.27
GC content: 61.43
Gene sequence:
>1338_bases ATGCTGACCTTACGAACTGTGGCTGACCTGCTGCAAACTCCCCTGCAGGGGGATCCCCATTTGTTGGGTCTTCCCGTCCA AGCCATTTGCACCGACAGCCGCCAACTCCAGCCAGGCTCAGTCTTCGTGGCGCTGCGGGGGGAACGGTTTGATGGACACA ACTTTATTCCACAAGCTTTGGCAAGGGGGGCCGTTGCCGTCATCAGCCAGCGTCCGGTGGCTGGGCCCCATTTTCAAGTC TCAGATACCCTAGCTGCCTACCAGCGCATTGCCAGAGGCTGGCGGGAGCAGTTTCCCCCCTCCGTAGTAGCCATCACGGG CTCAGCAGGCAAAACCACCACCAAGGAAATGCTGGCGGCTGCCCTATCCCGCTACGGCACAGTTCTCAAAAGTGAGGCCA ACCACAACAACGACATCGGGGTTGCTCAAACCCTGCTCCAGATGCGACCGGAGCATCAGTTTGTGGTTCTGGAAATGGCC ATGCGAGGCCCCGGAGAAATTCGCCGCCTGGCTCAGATGGCTCAGCCCACCCACGCCTTGATCACCCATATTGGCACCGC CCACATCGGCAGACTGGGATCCCGCGCGGCCATTGCTGCTGCCAAGTGCGAGCTGCTGCAGGAGCTAGGGCAGGGGGTGG CTCTGCTGAATGGAGAAGATCCCTTGCTGTTGTCTACCGCCGCCAGCCTGTGGTCGGGACAAACCCTTACCTATGGCCTG GATCAGGGGGACTTACGAGGAGAATGGGATCCCCAAGCCCAAACGGTAACCGTGGAGGGCCTAACGCTGCCGGTGCCCTT GCCGGGAAGACACCATGCCCTCAACTGGATGGGGGTGCTGGCTGCTTTGCGCAGCTTGGGGCTGGATTGGGAGCGGCTCC GAGAACCCATCGCCTTGCCTACCCCTCTGGAGGGGCGCAACCGCCATCTCAAGCTGGCAGGAGATGTGGAAATCTGGGAC GAAACCTACAACGCCTCGCCGGAAGCGATGATCGCGGCTCTACACCTGCTGGCCCAAACCCCGGGAAAACGGCGCTGGGC CATTCTCGGCCCGATGCGGGAGTTGGGAGAGCATGCGCCTCAGCTCTATGCAGAGGTGGGTCGGGCGGCTGCCCCTCTGG GGCTGGATCGGATCTTGCTCTTGGATCCCGAAGGAGAAATGCAACCGCTGCTCGACCAAAAACCGGCAGCCCAGACAGAA CGCTGCGAGGAGGTATCCGAACTGCTGGAAATCTTGCTCCATCACGTGCAAGCCGGGGATCGGCTGCTGTTCAAGGCAGC GCGGGCTGTTGAACTGGAGCGGGTGCTGCACCGCTTTTTGCAGGAGTGGCAGGCGTAG
Upstream 100 bases:
>100_bases AGAGGGGCTGGGGGTGAGGGGGAGCGCTTGGGAAATGTCTCAATCGGGTCTGAAATGACCATAGACGAAGAGGCTGTAGG CGAATTGGAGTTTCTGCCCG
Downstream 100 bases:
>100_bases GCTAAGCTAAGAAACGGCTGATGAAAAGCCCGCGTCCCTCTGTTGAGAGGGGCTTAGCCCAAGCCGGGCTCATTCCTCGT CGATAGCTGCCTTCTGTACG
Product: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase
Products: NA
Alternate protein names: D-alanyl-D-alanine-adding enzyme; UDP-MurNAc-pentapeptide synthetase [H]
Number of amino acids: Translated: 445; Mature: 445
Protein sequence:
>445_residues MLTLRTVADLLQTPLQGDPHLLGLPVQAICTDSRQLQPGSVFVALRGERFDGHNFIPQALARGAVAVISQRPVAGPHFQV SDTLAAYQRIARGWREQFPPSVVAITGSAGKTTTKEMLAAALSRYGTVLKSEANHNNDIGVAQTLLQMRPEHQFVVLEMA MRGPGEIRRLAQMAQPTHALITHIGTAHIGRLGSRAAIAAAKCELLQELGQGVALLNGEDPLLLSTAASLWSGQTLTYGL DQGDLRGEWDPQAQTVTVEGLTLPVPLPGRHHALNWMGVLAALRSLGLDWERLREPIALPTPLEGRNRHLKLAGDVEIWD ETYNASPEAMIAALHLLAQTPGKRRWAILGPMRELGEHAPQLYAEVGRAAAPLGLDRILLLDPEGEMQPLLDQKPAAQTE RCEEVSELLEILLHHVQAGDRLLFKAARAVELERVLHRFLQEWQA
Sequences:
>Translated_445_residues MLTLRTVADLLQTPLQGDPHLLGLPVQAICTDSRQLQPGSVFVALRGERFDGHNFIPQALARGAVAVISQRPVAGPHFQV SDTLAAYQRIARGWREQFPPSVVAITGSAGKTTTKEMLAAALSRYGTVLKSEANHNNDIGVAQTLLQMRPEHQFVVLEMA MRGPGEIRRLAQMAQPTHALITHIGTAHIGRLGSRAAIAAAKCELLQELGQGVALLNGEDPLLLSTAASLWSGQTLTYGL DQGDLRGEWDPQAQTVTVEGLTLPVPLPGRHHALNWMGVLAALRSLGLDWERLREPIALPTPLEGRNRHLKLAGDVEIWD ETYNASPEAMIAALHLLAQTPGKRRWAILGPMRELGEHAPQLYAEVGRAAAPLGLDRILLLDPEGEMQPLLDQKPAAQTE RCEEVSELLEILLHHVQAGDRLLFKAARAVELERVLHRFLQEWQA >Mature_445_residues MLTLRTVADLLQTPLQGDPHLLGLPVQAICTDSRQLQPGSVFVALRGERFDGHNFIPQALARGAVAVISQRPVAGPHFQV SDTLAAYQRIARGWREQFPPSVVAITGSAGKTTTKEMLAAALSRYGTVLKSEANHNNDIGVAQTLLQMRPEHQFVVLEMA MRGPGEIRRLAQMAQPTHALITHIGTAHIGRLGSRAAIAAAKCELLQELGQGVALLNGEDPLLLSTAASLWSGQTLTYGL DQGDLRGEWDPQAQTVTVEGLTLPVPLPGRHHALNWMGVLAALRSLGLDWERLREPIALPTPLEGRNRHLKLAGDVEIWD ETYNASPEAMIAALHLLAQTPGKRRWAILGPMRELGEHAPQLYAEVGRAAAPLGLDRILLLDPEGEMQPLLDQKPAAQTE RCEEVSELLEILLHHVQAGDRLLFKAARAVELERVLHRFLQEWQA
Specific function: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein [H]
COG id: COG0770
COG function: function code M; UDP-N-acetylmuramyl pentapeptide synthase
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1786274, Length=457, Percent_Identity=33.6980306345733, Blast_Score=205, Evalue=4e-54,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005863 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.10 [H]
Molecular weight: Translated: 48654; Mature: 48654
Theoretical pI: Translated: 6.62; Mature: 6.62
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLTLRTVADLLQTPLQGDPHLLGLPVQAICTDSRQLQPGSVFVALRGERFDGHNFIPQAL CCCHHHHHHHHHCCCCCCCCEECCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHH ARGAVAVISQRPVAGPHFQVSDTLAAYQRIARGWREQFPPSVVAITGSAGKTTTKEMLAA HCCHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH ALSRYGTVLKSEANHNNDIGVAQTLLQMRPEHQFVVLEMAMRGPGEIRRLAQMAQPTHAL HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCCCHHHHHHHHHHCCHHHH ITHIGTAHIGRLGSRAAIAAAKCELLQELGQGVALLNGEDPLLLSTAASLWSGQTLTYGL HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHCCCEEEEEC DQGDLRGEWDPQAQTVTVEGLTLPVPLPGRHHALNWMGVLAALRSLGLDWERLREPIALP CCCCCCCCCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCC TPLEGRNRHLKLAGDVEIWDETYNASPEAMIAALHLLAQTPGKRRWAILGPMRELGEHAP CCCCCCCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHH QLYAEVGRAAAPLGLDRILLLDPEGEMQPLLDQKPAAQTERCEEVSELLEILLHHVQAGD HHHHHHHHHCCCCCCCEEEEECCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC RLLFKAARAVELERVLHRFLQEWQA HHHHHHHHHHHHHHHHHHHHHHHCC >Mature Secondary Structure MLTLRTVADLLQTPLQGDPHLLGLPVQAICTDSRQLQPGSVFVALRGERFDGHNFIPQAL CCCHHHHHHHHHCCCCCCCCEECCCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHHH ARGAVAVISQRPVAGPHFQVSDTLAAYQRIARGWREQFPPSVVAITGSAGKTTTKEMLAA HCCHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH ALSRYGTVLKSEANHNNDIGVAQTLLQMRPEHQFVVLEMAMRGPGEIRRLAQMAQPTHAL HHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEEHHCCCHHHHHHHHHHCCHHHH ITHIGTAHIGRLGSRAAIAAAKCELLQELGQGVALLNGEDPLLLSTAASLWSGQTLTYGL HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHCCCEEEEEC DQGDLRGEWDPQAQTVTVEGLTLPVPLPGRHHALNWMGVLAALRSLGLDWERLREPIALP CCCCCCCCCCCCCCEEEECCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCC TPLEGRNRHLKLAGDVEIWDETYNASPEAMIAALHLLAQTPGKRRWAILGPMRELGEHAP CCCCCCCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHH QLYAEVGRAAAPLGLDRILLLDPEGEMQPLLDQKPAAQTERCEEVSELLEILLHHVQAGD HHHHHHHHHCCCCCCCEEEEECCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC RLLFKAARAVELERVLHRFLQEWQA HHHHHHHHHHHHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7894708; 8905231 [H]