| Definition | Synechococcus sp. JA-2-3B'a(2-13), complete genome. |
|---|---|
| Accession | NC_007776 |
| Length | 3,046,682 |
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The map label for this gene is ndhD2 [H]
Identifier: 86609453
GI number: 86609453
Start: 2109129
End: 2110733
Strand: Reverse
Name: ndhD2 [H]
Synonym: CYB_2004
Alternate gene names: 86609453
Gene position: 2110733-2109129 (Counterclockwise)
Preceding gene: 86609456
Following gene: 86609450
Centisome position: 69.28
GC content: 58.88
Gene sequence:
>1605_bases ATGGCGCTGCCCAGCTTGCACGAGTTTCCTTGGCTGACCACGGTCATCGCTTACCCTGTGTTGGCCGCCCTATTTATTCC CCTGATCCCAGCACCGGCTGGGGATCCCAGTACCCGCGCCTACGCACAAAAGTTGGCCGAGCGGATCCGCTGGTTTGCTT TGTTCATTGCGGTCACGGATCTGCTGATTCTGCTGGCCGGCTTCTATGTCGGCTACGATCCCGGCCAGACGGGCTTGCAA CTGCTGGAGCGCTACACCTGGGTACCCCAAGTGGGCTTGAGTTGGTCGGTGGGGGCTGATGGCCTCTCCATGCCCCTGAT CCTGCTCACGGCGTTTATCACTACCCTAGCCATCTTGGCCGCTTGGCCGGTCACCCTCAAACCTCGCCTCTTCTACTTTT TGATGCTGGCCATGTACGGCGGGCAGATCGGGGTGTTTGCCGTGCAGGACATGTTGCTGTTTTTCCTGATGTGGGAATTG GAGCTGATCCCGGTGTACTTGCTCCTCTCCATTTGGGGTGGGGCAAACCGCCTCTATGCGGCCACCAAGTTCATCCTCTA CACGGCTCTCAGCTCCCTGTTTATCCTGGTGGCAGGTCTGGCTATGGCCTTCTACGGGGATCCCATCAGCTTTGACATGA CGGATCTGGCCCACAAGACCTATCCACTCACCTTCCAACTGCTGATGTATGGGGCCTTCCTCATTGCCTATGGGGTGAAG CTGCCCATTTTCCCCTTGCACACTTGGCTGCCCGATGCCCACGGCGAGGCCACTGCGCCGGTGCACATGTTGCTGGCCGG GATCCTGCTCAAGATGGGGGGCTATGCCCTGATGCGCATGAATGCGGGCATGCTGCCGGATGCTCATCTTTACTTTGCGC CGGTGCTGATCGTGTTGGGGGTGGTGAACATCATCTTTGCCGCCCTCACCTCTTTTGCCCAGCGCAACCTGAAACGGAAG ATCGCCTGTTCTTCCATCAGCCACATGGGCTTCGTGCTCATCGGTATCGGATCCCTGACGGAGATCGGCATGAGCGGCGC CATGCTGCAGATGATCTCCCACGGGCTGATCGGGGCCAGCCTGTTCTTTTTGGTGGGGGCCACCTACGACCGCACCCATA CGCTGGAGCTGGAAGAAATGGGCGGCGTTGGCCTGAAGATGCCCAAGATCTTCTCCATGTTCACCGCCTGCTCCCTGGCT TCGCTAGCCCTACCCGGCATGAGCGGCTTTGTGGCCGAGATCATGGTGTTTATCGGCATGGCCACCACCGATGCCTACTC TCTCCCCTTCCGGTTGGTGGTGGTTTTCCTGGCAGCAGTTGGGGTGATCCTGACCCCCATCTACCTGCTGTCGATGTTGC GGCAGATTTTCTTTGGCCCGGAGAACAAAGAGCTCACCGAACACGAAGAATTGGTAGATGCTGAGCCACGCGAGGTGTTC ATCATCGCCTGCCTGTTGATCCCCATCATCGGCATTGGGCTCTACCCCAAGCTGGTGACCAGCCTCTACGACCAATCCAC CAACGCCTTGGTGGCGCTGCTGCGGCAGGAGCTGCCTCAAACTGGTGAGACGGTTGCCCAAGCTCCTGCCCTCTACAACA ACTGA
Upstream 100 bases:
>100_bases TTGCTAAGCATAGATACTCAAGGGCGATTCTGGTAAAGGGCTGTCGGATTGCAGCCGGCAGGGATCCCCCTGATGGTATG GCACAAGCGAGGTTACATCC
Downstream 100 bases:
>100_bases ATAATAATGTTGAATTGAGATGAGAACTGAGGGTCGGAAAGGGATCCACTCTCTTTCTATCCCCTATTGGACTTGTGGCT CTCGCCAGCTTGAACTTGCA
Product: NAD(P)H-quinone oxidoreductase subunit 4
Products: NAD+; ubiquinol
Alternate protein names: NAD(P)H dehydrogenase I, chain 4 2; NDH-1, chain 4 2 [H]
Number of amino acids: Translated: 534; Mature: 533
Protein sequence:
>534_residues MALPSLHEFPWLTTVIAYPVLAALFIPLIPAPAGDPSTRAYAQKLAERIRWFALFIAVTDLLILLAGFYVGYDPGQTGLQ LLERYTWVPQVGLSWSVGADGLSMPLILLTAFITTLAILAAWPVTLKPRLFYFLMLAMYGGQIGVFAVQDMLLFFLMWEL ELIPVYLLLSIWGGANRLYAATKFILYTALSSLFILVAGLAMAFYGDPISFDMTDLAHKTYPLTFQLLMYGAFLIAYGVK LPIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRMNAGMLPDAHLYFAPVLIVLGVVNIIFAALTSFAQRNLKRK IACSSISHMGFVLIGIGSLTEIGMSGAMLQMISHGLIGASLFFLVGATYDRTHTLELEEMGGVGLKMPKIFSMFTACSLA SLALPGMSGFVAEIMVFIGMATTDAYSLPFRLVVVFLAAVGVILTPIYLLSMLRQIFFGPENKELTEHEELVDAEPREVF IIACLLIPIIGIGLYPKLVTSLYDQSTNALVALLRQELPQTGETVAQAPALYNN
Sequences:
>Translated_534_residues MALPSLHEFPWLTTVIAYPVLAALFIPLIPAPAGDPSTRAYAQKLAERIRWFALFIAVTDLLILLAGFYVGYDPGQTGLQ LLERYTWVPQVGLSWSVGADGLSMPLILLTAFITTLAILAAWPVTLKPRLFYFLMLAMYGGQIGVFAVQDMLLFFLMWEL ELIPVYLLLSIWGGANRLYAATKFILYTALSSLFILVAGLAMAFYGDPISFDMTDLAHKTYPLTFQLLMYGAFLIAYGVK LPIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRMNAGMLPDAHLYFAPVLIVLGVVNIIFAALTSFAQRNLKRK IACSSISHMGFVLIGIGSLTEIGMSGAMLQMISHGLIGASLFFLVGATYDRTHTLELEEMGGVGLKMPKIFSMFTACSLA SLALPGMSGFVAEIMVFIGMATTDAYSLPFRLVVVFLAAVGVILTPIYLLSMLRQIFFGPENKELTEHEELVDAEPREVF IIACLLIPIIGIGLYPKLVTSLYDQSTNALVALLRQELPQTGETVAQAPALYNN >Mature_533_residues ALPSLHEFPWLTTVIAYPVLAALFIPLIPAPAGDPSTRAYAQKLAERIRWFALFIAVTDLLILLAGFYVGYDPGQTGLQL LERYTWVPQVGLSWSVGADGLSMPLILLTAFITTLAILAAWPVTLKPRLFYFLMLAMYGGQIGVFAVQDMLLFFLMWELE LIPVYLLLSIWGGANRLYAATKFILYTALSSLFILVAGLAMAFYGDPISFDMTDLAHKTYPLTFQLLMYGAFLIAYGVKL PIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRMNAGMLPDAHLYFAPVLIVLGVVNIIFAALTSFAQRNLKRKI ACSSISHMGFVLIGIGSLTEIGMSGAMLQMISHGLIGASLFFLVGATYDRTHTLELEEMGGVGLKMPKIFSMFTACSLAS LALPGMSGFVAEIMVFIGMATTDAYSLPFRLVVVFLAAVGVILTPIYLLSMLRQIFFGPENKELTEHEELVDAEPREVFI IACLLIPIIGIGLYPKLVTSLYDQSTNALVALLRQELPQTGETVAQAPALYNN
Specific function: NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton tran
COG id: COG1008
COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)
Gene ontology:
Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the complex I subunit 4 family [H]
Homologues:
Organism=Homo sapiens, GI251831116, Length=377, Percent_Identity=29.973474801061, Blast_Score=135, Evalue=1e-31, Organism=Homo sapiens, GI251831117, Length=377, Percent_Identity=25.7294429708223, Blast_Score=70, Evalue=6e-12, Organism=Escherichia coli, GI1788613, Length=476, Percent_Identity=35.9243697478992, Blast_Score=273, Evalue=2e-74, Organism=Escherichia coli, GI1788827, Length=391, Percent_Identity=23.2736572890026, Blast_Score=104, Evalue=2e-23, Organism=Escherichia coli, GI1788831, Length=307, Percent_Identity=27.6872964169381, Blast_Score=89, Evalue=6e-19, Organism=Escherichia coli, GI2367154, Length=224, Percent_Identity=27.2321428571429, Blast_Score=82, Evalue=1e-16, Organism=Escherichia coli, GI1788614, Length=435, Percent_Identity=23.2183908045977, Blast_Score=65, Evalue=8e-12, Organism=Escherichia coli, GI1788829, Length=295, Percent_Identity=26.4406779661017, Blast_Score=65, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR022997 - InterPro: IPR010227 - InterPro: IPR001750 - InterPro: IPR003918 [H]
Pfam domain/function: PF00361 Oxidored_q1 [H]
EC number: 1.6.5.3
Molecular weight: Translated: 58435; Mature: 58303
Theoretical pI: Translated: 5.99; Mature: 5.99
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 4.7 %Met (Translated Protein) 5.2 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 4.5 %Met (Mature Protein) 5.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MALPSLHEFPWLTTVIAYPVLAALFIPLIPAPAGDPSTRAYAQKLAERIRWFALFIAVTD CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH LLILLAGFYVGYDPGQTGLQLLERYTWVPQVGLSWSVGADGLSMPLILLTAFITTLAILA HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH AWPVTLKPRLFYFLMLAMYGGQIGVFAVQDMLLFFLMWELELIPVYLLLSIWGGANRLYA HCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH ATKFILYTALSSLFILVAGLAMAFYGDPISFDMTDLAHKTYPLTFQLLMYGAFLIAYGVK HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC LPIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRMNAGMLPDAHLYFAPVLIVLG CCCEEHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHEEEECCCCCCCHHHHHHHHHHHHH VVNIIFAALTSFAQRNLKRKIACSSISHMGFVLIGIGSLTEIGMSGAMLQMISHGLIGAS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHCCCHHHHHHHHHHHHHHH LFFLVGATYDRTHTLELEEMGGVGLKMPKIFSMFTACSLASLALPGMSGFVAEIMVFIGM HHHHHCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH ATTDAYSLPFRLVVVFLAAVGVILTPIYLLSMLRQIFFGPENKELTEHEELVDAEPREVF HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHH IIACLLIPIIGIGLYPKLVTSLYDQSTNALVALLRQELPQTGETVAQAPALYNN HHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCC >Mature Secondary Structure ALPSLHEFPWLTTVIAYPVLAALFIPLIPAPAGDPSTRAYAQKLAERIRWFALFIAVTD CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH LLILLAGFYVGYDPGQTGLQLLERYTWVPQVGLSWSVGADGLSMPLILLTAFITTLAILA HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH AWPVTLKPRLFYFLMLAMYGGQIGVFAVQDMLLFFLMWELELIPVYLLLSIWGGANRLYA HCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH ATKFILYTALSSLFILVAGLAMAFYGDPISFDMTDLAHKTYPLTFQLLMYGAFLIAYGVK HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCC LPIFPLHTWLPDAHGEATAPVHMLLAGILLKMGGYALMRMNAGMLPDAHLYFAPVLIVLG CCCEEHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHEEEECCCCCCCHHHHHHHHHHHHH VVNIIFAALTSFAQRNLKRKIACSSISHMGFVLIGIGSLTEIGMSGAMLQMISHGLIGAS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHCCCHHHHHHHHHHHHHHH LFFLVGATYDRTHTLELEEMGGVGLKMPKIFSMFTACSLASLALPGMSGFVAEIMVFIGM HHHHHCCCCCCCEEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH ATTDAYSLPFRLVVVFLAAVGVILTPIYLLSMLRQIFFGPENKELTEHEELVDAEPREVF HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHH IIACLLIPIIGIGLYPKLVTSLYDQSTNALVALLRQELPQTGETVAQAPALYNN HHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NADH; H+; ubiquinone
Specific reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA