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The map label for this gene is argS [H]

Identifier: 86609400

GI number: 86609400

Start: 2036152

End: 2037948

Strand: Direct

Name: argS [H]

Synonym: CYB_1944

Alternate gene names: 86609400

Gene position: 2036152-2037948 (Clockwise)

Preceding gene: 86609396

Following gene: 86609403

Centisome position: 66.83

GC content: 58.15

Gene sequence:

>1797_bases
ATGGCCACTCAACCCGTATCCACCTCGCTGATTCGGTTTCTCACCGCCGCCGTAGCCGAGAGCATTCGACGGGCCTCAGA
GGCGGGGCAACTGGGATCCCTGGCCCCCCAGCAAGCCACAGCGATTGCCCCCGTGATCCAGATCCCCAGCGACCCTCGCT
ACGGCGATTACGCCTGTCCCACCCCCCTGGGCATGGCCAAGCTCTGCCGCCTAGCACCGGCCCAGATCGCCCAAACCCTG
CAAAAACACTTGGATCTGCCGGACATCGAAACTCAGGTGGCGGGAGGAGGGTATCTCAACTTCCGGCTGGGGGATCCCTT
TTTGGCCAAGCGCTTGCAAGAGCTGCTGCATCTGGGAGAAAACTTCGGCAAAACAGCCATTCCCCATCCTGAGCGCATTC
TGCTGGAGTTTGTCTCCGCCAACCCGACGGGGCCTTTGCACGTCGGCCATGGGCGCTGGGCTGCCGTTGGCTCTACGTTG
GCCAACTTGCTGCACTGGACGGGCCACCAGGTGGAGCGGGAGTTTTACATCAACGATGCCGGCAACCAGATGCGGCTCTT
GGGCCAGTCTCTGGAGGTGCGGGTGCGGCAACTGCAGGGGGAAGAGGTGGCTCTGCCCGAAGATGCCTACCATGGCAGTT
ACTTGGTCGATATTGCCCGGCGGCTGTTGGGTCAGGTCAAGGCCGGGATCCGCCCTCTGCCCACCACCCTAGAGGAGTAC
ACCGATTTTGCCTATGGGGAAATGCTGGCCTGGCAAAAGCAGACCCTGCAACAACTACGCACCGAGTTTGATCACTGGTT
TAGCGAGCGCCGCCTGCACACCCCCGATCCCCAGACAGGCCTGAGCGCCATCCAGCAAGCTTTGCAGGAGCTGCAAGAGC
GCGGCTTTCTCTACAAAGCCAAAGCGCCGCGGGGTGAGGATCCCAAGCCAGGGGCCGAAGAGGCCGTCTATTTCAAAACC
CAAGAATTTGGCGACGACAAGGATCGGGTGGTGCAAAAGGCCGATGGTTCGTTCACTTATCTAGCCGCCGATATTGCCTA
CCATCGGGATAAAGTGCAGCGGGGATATCACCGGCTGATCAACATTCTTGGCTCGGATCACCATGGCTATATCGGCCGCT
TAAAGGCGGCGGTGGGTGCCTTCAGCCCAGATGTCAAGCTGGAAATCTTGATTGGACAATTTGTCAAATTGTTCAAAACC
GACCCGCAAACCGGTGAGAAAACCGAAGTGCGCATGTCCAAGCGCACCGGCAACTTTGTCTCACTCAATGACCTGATCGA
AGATCCAGAAATTGGCGTGGGGGTCGATGCAGCCCGCTGGTTTTTGCTTAGCAGCAGCATGGACAGCCCCATCAACTTCG
ATTTGGATTTGGCCGTCAAGCAAACTTTCGATAACCCAGTCGTGTATGTTCACTACAGCCATGCCCGCTGTTGCACTCTG
CTGCGGCGGCTACAGGAAGAAGAAAAGGTTGAACTGACCAACAAAGTCCCTTTGACGGAGCAACAAAAACTGCCCTACAA
AGAGCCAGAAGAGCGGGCCCTGCTGCTGCGCTTGTTGGCCTTGCCGGATGAGCTGATCGCCGCTGCCGAAGAGCGCGCTC
CCCACAAGATCATCCGCTATGCAGAAGCCATCGCCGCCGATTTCAACAAGTTTTACGACAACTGCCGTATTTTGCCGCTC
TTGAAAGAGGATCCCCTTTTGGCCCAAGCCCGCATCCAATTGGTGCAGGCCACGCAGCAGGTTTTGTTTAACGTCCTCAC
CGGCATTCTCGGCCTGAGCGCGCCGGAGTCTATGTGA

Upstream 100 bases:

>100_bases
GTCAGATTTTGTCAGAGCCGGTTGGCTGTCGATATGATGATGCTTTTACTGCCCCAGGCATCCCTGGAACCTCTCTCGAC
GTCTGCCGACACGAACAGCC

Downstream 100 bases:

>100_bases
TTTACGAAGGAGTGCCGTAAGGCCCCCAGCTCACGCTCTGGGCGGAAGCCAGCTATAGCGGTCGCGAGTAGGTCAATTGC
AATAAACCGTTCCACAACGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 598; Mature: 597

Protein sequence:

>598_residues
MATQPVSTSLIRFLTAAVAESIRRASEAGQLGSLAPQQATAIAPVIQIPSDPRYGDYACPTPLGMAKLCRLAPAQIAQTL
QKHLDLPDIETQVAGGGYLNFRLGDPFLAKRLQELLHLGENFGKTAIPHPERILLEFVSANPTGPLHVGHGRWAAVGSTL
ANLLHWTGHQVEREFYINDAGNQMRLLGQSLEVRVRQLQGEEVALPEDAYHGSYLVDIARRLLGQVKAGIRPLPTTLEEY
TDFAYGEMLAWQKQTLQQLRTEFDHWFSERRLHTPDPQTGLSAIQQALQELQERGFLYKAKAPRGEDPKPGAEEAVYFKT
QEFGDDKDRVVQKADGSFTYLAADIAYHRDKVQRGYHRLINILGSDHHGYIGRLKAAVGAFSPDVKLEILIGQFVKLFKT
DPQTGEKTEVRMSKRTGNFVSLNDLIEDPEIGVGVDAARWFLLSSSMDSPINFDLDLAVKQTFDNPVVYVHYSHARCCTL
LRRLQEEEKVELTNKVPLTEQQKLPYKEPEERALLLRLLALPDELIAAAEERAPHKIIRYAEAIAADFNKFYDNCRILPL
LKEDPLLAQARIQLVQATQQVLFNVLTGILGLSAPESM

Sequences:

>Translated_598_residues
MATQPVSTSLIRFLTAAVAESIRRASEAGQLGSLAPQQATAIAPVIQIPSDPRYGDYACPTPLGMAKLCRLAPAQIAQTL
QKHLDLPDIETQVAGGGYLNFRLGDPFLAKRLQELLHLGENFGKTAIPHPERILLEFVSANPTGPLHVGHGRWAAVGSTL
ANLLHWTGHQVEREFYINDAGNQMRLLGQSLEVRVRQLQGEEVALPEDAYHGSYLVDIARRLLGQVKAGIRPLPTTLEEY
TDFAYGEMLAWQKQTLQQLRTEFDHWFSERRLHTPDPQTGLSAIQQALQELQERGFLYKAKAPRGEDPKPGAEEAVYFKT
QEFGDDKDRVVQKADGSFTYLAADIAYHRDKVQRGYHRLINILGSDHHGYIGRLKAAVGAFSPDVKLEILIGQFVKLFKT
DPQTGEKTEVRMSKRTGNFVSLNDLIEDPEIGVGVDAARWFLLSSSMDSPINFDLDLAVKQTFDNPVVYVHYSHARCCTL
LRRLQEEEKVELTNKVPLTEQQKLPYKEPEERALLLRLLALPDELIAAAEERAPHKIIRYAEAIAADFNKFYDNCRILPL
LKEDPLLAQARIQLVQATQQVLFNVLTGILGLSAPESM
>Mature_597_residues
ATQPVSTSLIRFLTAAVAESIRRASEAGQLGSLAPQQATAIAPVIQIPSDPRYGDYACPTPLGMAKLCRLAPAQIAQTLQ
KHLDLPDIETQVAGGGYLNFRLGDPFLAKRLQELLHLGENFGKTAIPHPERILLEFVSANPTGPLHVGHGRWAAVGSTLA
NLLHWTGHQVEREFYINDAGNQMRLLGQSLEVRVRQLQGEEVALPEDAYHGSYLVDIARRLLGQVKAGIRPLPTTLEEYT
DFAYGEMLAWQKQTLQQLRTEFDHWFSERRLHTPDPQTGLSAIQQALQELQERGFLYKAKAPRGEDPKPGAEEAVYFKTQ
EFGDDKDRVVQKADGSFTYLAADIAYHRDKVQRGYHRLINILGSDHHGYIGRLKAAVGAFSPDVKLEILIGQFVKLFKTD
PQTGEKTEVRMSKRTGNFVSLNDLIEDPEIGVGVDAARWFLLSSSMDSPINFDLDLAVKQTFDNPVVYVHYSHARCCTLL
RRLQEEEKVELTNKVPLTEQQKLPYKEPEERALLLRLLALPDELIAAAEERAPHKIIRYAEAIAADFNKFYDNCRILPLL
KEDPLLAQARIQLVQATQQVLFNVLTGILGLSAPESM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=154, Percent_Identity=29.2207792207792, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI197100773, Length=566, Percent_Identity=22.4381625441696, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1788184, Length=638, Percent_Identity=25.5485893416928, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6320548, Length=617, Percent_Identity=23.1766612641815, Blast_Score=100, Evalue=9e-22,
Organism=Drosophila melanogaster, GI18859963, Length=612, Percent_Identity=23.6928104575163, Blast_Score=105, Evalue=9e-23,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 66875; Mature: 66744

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATQPVSTSLIRFLTAAVAESIRRASEAGQLGSLAPQQATAIAPVIQIPSDPRYGDYACP
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCC
TPLGMAKLCRLAPAQIAQTLQKHLDLPDIETQVAGGGYLNFRLGDPFLAKRLQELLHLGE
CCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
NFGKTAIPHPERILLEFVSANPTGPLHVGHGRWAAVGSTLANLLHWTGHQVEREFYINDA
HCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHEEEEEECCC
GNQMRLLGQSLEVRVRQLQGEEVALPEDAYHGSYLVDIARRLLGQVKAGIRPLPTTLEEY
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TDFAYGEMLAWQKQTLQQLRTEFDHWFSERRLHTPDPQTGLSAIQQALQELQERGFLYKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEE
KAPRGEDPKPGAEEAVYFKTQEFGDDKDRVVQKADGSFTYLAADIAYHRDKVQRGYHRLI
CCCCCCCCCCCCCCEEEEEHHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHH
NILGSDHHGYIGRLKAAVGAFSPDVKLEILIGQFVKLFKTDPQTGEKTEVRMSKRTGNFV
HHHCCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCHHHEEHHCCCCEE
SLNDLIEDPEIGVGVDAARWFLLSSSMDSPINFDLDLAVKQTFDNPVVYVHYSHARCCTL
EHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCEEEEEECHHHHHHH
LRRLQEEEKVELTNKVPLTEQQKLPYKEPEERALLLRLLALPDELIAAAEERAPHKIIRY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHH
AEAIAADFNKFYDNCRILPLLKEDPLLAQARIQLVQATQQVLFNVLTGILGLSAPESM
HHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATQPVSTSLIRFLTAAVAESIRRASEAGQLGSLAPQQATAIAPVIQIPSDPRYGDYACP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEECCCCCCCCCCCCC
TPLGMAKLCRLAPAQIAQTLQKHLDLPDIETQVAGGGYLNFRLGDPFLAKRLQELLHLGE
CCCCHHHHHHCCHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
NFGKTAIPHPERILLEFVSANPTGPLHVGHGRWAAVGSTLANLLHWTGHQVEREFYINDA
HCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCCCHHEEEEEECCC
GNQMRLLGQSLEVRVRQLQGEEVALPEDAYHGSYLVDIARRLLGQVKAGIRPLPTTLEEY
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
TDFAYGEMLAWQKQTLQQLRTEFDHWFSERRLHTPDPQTGLSAIQQALQELQERGFLYKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEE
KAPRGEDPKPGAEEAVYFKTQEFGDDKDRVVQKADGSFTYLAADIAYHRDKVQRGYHRLI
CCCCCCCCCCCCCCEEEEEHHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHH
NILGSDHHGYIGRLKAAVGAFSPDVKLEILIGQFVKLFKTDPQTGEKTEVRMSKRTGNFV
HHHCCCCCCHHHHHHHHHHCCCCCCEEEHHHHHHHHHHCCCCCCCCCHHHEEHHCCCCEE
SLNDLIEDPEIGVGVDAARWFLLSSSMDSPINFDLDLAVKQTFDNPVVYVHYSHARCCTL
EHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCEEEEEECHHHHHHH
LRRLQEEEKVELTNKVPLTEQQKLPYKEPEERALLLRLLALPDELIAAAEERAPHKIIRY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHH
AEAIAADFNKFYDNCRILPLLKEDPLLAQARIQLVQATQQVLFNVLTGILGLSAPESM
HHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA