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The map label for this gene is ribE [H]

Identifier: 86609196

GI number: 86609196

Start: 1819553

End: 1820191

Strand: Reverse

Name: ribE [H]

Synonym: CYB_1738

Alternate gene names: 86609196

Gene position: 1820191-1819553 (Counterclockwise)

Preceding gene: 86609197

Following gene: 86609195

Centisome position: 59.74

GC content: 58.69

Gene sequence:

>639_bases
ATGTTTACGGGTCTGGTTCGAAGTTTGGGCACAGCCCAGTTGATCAATTCTTCACAGCTACGGGTTACCTGTCCCCGGTT
GCAACCTCAGTTGGCCTATGGAGATAGCGTGGCGGTGGACGGCCTTTGCCTGACGGTGGTGGAGATTCTGCCCGATGGAT
TTTTGGCCGATGTTTCGCCGGAAACCCTGCGGCGCTCGACTTGGGGCCACGGATCCCCCGGCCCGCGCACAGTCAACCTG
GAACCGGCGCTGCGGGTAGGAGACAAGTTAGGGGGGCATTTTGTCAGCGGCCATATCGATGGGGTGGGGCAACTGTGGGA
TCAAGCCGCCACCGGCAACGCCTGGGAGCTGAGCTTCAAGGTTCCTGAAGAGATCGGGCGTTACATCGTACCCAAGGGCA
GCGTGGCGGTGAATGGGGTGAGCTTGACCATTGCTGAGGTGCGCCAAGGGGGCTGCTGGTTCAAGGTGGCTGTGATCCCC
CAAACCTACCGCGAGACCAACCTTTCTCAGCTCCAAGTTGGGGATCCCGTCAACATAGAGGCGGATATTTTGGGCAAGTA
TGTGGAAAAATTGCTGGGCTTGCTGCCCCCCGAGAGCAGCGTTTCTCTGGAGTTTCTGGCCGAGCATGGCTATATCTAG

Upstream 100 bases:

>100_bases
GAAAGCCCGACAAGAGCGAATCGCTGCCGAAAAACGAGCCAAAGAGCGAGAAAAACAGAAAGCCAAAAAGGCAGCCGGCA
AAACCTAAGGAGCCAAAGCA

Downstream 100 bases:

>100_bases
GTACCTTTCCCATGATCCACCCCGAGGAAGTTGAGCGCCTGCGCGGCGTAAATGTTTATCTCATTGGGATGATGGGCAGC
GGCAAATCCACCGTGGGATC

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFTGLVRSLGTAQLINSSQLRVTCPRLQPQLAYGDSVAVDGLCLTVVEILPDGFLADVSPETLRRSTWGHGSPGPRTVNL
EPALRVGDKLGGHFVSGHIDGVGQLWDQAATGNAWELSFKVPEEIGRYIVPKGSVAVNGVSLTIAEVRQGGCWFKVAVIP
QTYRETNLSQLQVGDPVNIEADILGKYVEKLLGLLPPESSVSLEFLAEHGYI

Sequences:

>Translated_212_residues
MFTGLVRSLGTAQLINSSQLRVTCPRLQPQLAYGDSVAVDGLCLTVVEILPDGFLADVSPETLRRSTWGHGSPGPRTVNL
EPALRVGDKLGGHFVSGHIDGVGQLWDQAATGNAWELSFKVPEEIGRYIVPKGSVAVNGVSLTIAEVRQGGCWFKVAVIP
QTYRETNLSQLQVGDPVNIEADILGKYVEKLLGLLPPESSVSLEFLAEHGYI
>Mature_212_residues
MFTGLVRSLGTAQLINSSQLRVTCPRLQPQLAYGDSVAVDGLCLTVVEILPDGFLADVSPETLRRSTWGHGSPGPRTVNL
EPALRVGDKLGGHFVSGHIDGVGQLWDQAATGNAWELSFKVPEEIGRYIVPKGSVAVNGVSLTIAEVRQGGCWFKVAVIP
QTYRETNLSQLQVGDPVNIEADILGKYVEKLLGLLPPESSVSLEFLAEHGYI

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=190, Percent_Identity=36.3157894736842, Blast_Score=96, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319733, Length=220, Percent_Identity=35.9090909090909, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22790; Mature: 22790

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLVRSLGTAQLINSSQLRVTCPRLQPQLAYGDSVAVDGLCLTVVEILPDGFLADVSP
CCHHHHHHHCHHHHCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCH
ETLRRSTWGHGSPGPRTVNLEPALRVGDKLGGHFVSGHIDGVGQLWDQAATGNAWELSFK
HHHHHCCCCCCCCCCEEEECCHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEE
VPEEIGRYIVPKGSVAVNGVSLTIAEVRQGGCWFKVAVIPQTYRETNLSQLQVGDPVNIE
CHHHCCCEECCCCCEEECCEEEEEEHHHCCCCEEEEEECCCCHHHCCCCEEECCCCCCCH
ADILGKYVEKLLGLLPPESSVSLEFLAEHGYI
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCC
>Mature Secondary Structure
MFTGLVRSLGTAQLINSSQLRVTCPRLQPQLAYGDSVAVDGLCLTVVEILPDGFLADVSP
CCHHHHHHHCHHHHCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCH
ETLRRSTWGHGSPGPRTVNLEPALRVGDKLGGHFVSGHIDGVGQLWDQAATGNAWELSFK
HHHHHCCCCCCCCCCEEEECCHHHHHHHHCCCEEEECCCCCHHHHHHHHCCCCEEEEEEE
VPEEIGRYIVPKGSVAVNGVSLTIAEVRQGGCWFKVAVIPQTYRETNLSQLQVGDPVNIE
CHHHCCCEECCCCCEEECCEEEEEEHHHCCCCEEEEEECCCCHHHCCCCEEECCCCCCCH
ADILGKYVEKLLGLLPPESSVSLEFLAEHGYI
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]