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The map label for this gene is thiO [H]

Identifier: 86609170

GI number: 86609170

Start: 1792911

End: 1794008

Strand: Direct

Name: thiO [H]

Synonym: CYB_1710

Alternate gene names: 86609170

Gene position: 1792911-1794008 (Clockwise)

Preceding gene: 86609169

Following gene: 86609171

Centisome position: 58.85

GC content: 64.21

Gene sequence:

>1098_bases
GTGATCGGCTGTGGGGTGGTGGGCTGTGCCATCGCCTACGAATTGTCTGCGGCTGGCCTATCGGTGGTTGGGATCGATGC
CGGGGATCCTGCCGCCGGCTCGACAGGGGCAGCTCTGGGGGTATTGGTGGGCATTTCCAGTCGGCAAGCGGGTGGGGAGA
CGGTTCAGCTTCGCCTGAAAAGCCTGGAGCTGTTCGATCCCCTAATCGCGCGGCTGGAGGAAGACCTGGGCCGGAGTTTG
CCCGTCAATCGGCGCGGCATTCTCAAACTCCTCAGGGAGGAGGAAGTGGAAGCTTGGCAAGAAACCCTGGTGGCCCGCCG
ACAAGCAGGTTACCGCCTAGATCTGCTCAGCCTTGCCGAAGTGGGATCCCTGCAGCCCGGCCTGCGCAGCGACCTGGCGG
CGGCCATCTACTCTCCCCAGGATCGACAAGTCCAACCCAAGCTCCTAACCCAGGCTCTCTTGGAAGCAGCCCAACGCAAG
GGATCCCGCTTTTTCTTCCACCAGCCTGTCCAGAAGATTCAGCGCAGCTCGGATCCCCCCTTTCGCCTGCAAACGGTCTA
CACGCCCGCTCTCACCCTCTCGGCAGGGCACGTCATCCTGGCGGCAGGTCTGGGCAGCTCTCCTCTGGCCAAAGAGCTGG
GGCTGCAGGTGCCGCTGCAAGCGGTCAAAGGTCAGGCCCTGCGGGTCAAAGCCCCCGGGATCCCCCTGGGGCCCGTGGTC
ACCGACGCGGATCTGCATCTGGTTCCCCTGGGGGATGGATCCCTGTGGGTGGGGGCAACAGTGGAATTTCAGGCCCCTCA
TCCCGAGCCGACGCTGCTGGCGCTACAAGATCTGCTGGCCCGCGCCATCCGACTCTGCCCGGCTTTGGCCGCAGCGACTT
TGTTGGATCATTGGGCCGGCCATCGGCCTCGACCAGTGGGACAGCGCGCCCCCATCCTGGGTTGGGCTCCTGGCTACGCC
AATCTGCTCATTGCCACCGGCCATTATCGCAATGGAGTGTTGCTGGCCCCGATCAGCGCCGCCATCCTGCGGGACTTGGT
ACTGAAAGGGGAAACAGCCCTCTGTGATCTAGGGCCCTTTGCCCCCAGACAGGGCTGA

Upstream 100 bases:

>100_bases
TGCCGGAAATTCGTGAATTGCACGATCGCAGCAACTCTGTGGAGTATCACTACGAAAAGCATCTCCATTGAGGGTTGGGC
TGTTGAACTGTGATGTGCTG

Downstream 100 bases:

>100_bases
GCCCGTATCCATCTTCCGGCTCTCGGCCCGCCGATGGACAGGACATATGTCAGAATGAAAGGCTGCCTGGTTAGGATCGG
ATCGTCCGTTGAGTAGCCCA

Product: oxidoreductase, FAD-binding

Products: NA

Alternate protein names: GO [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MIGCGVVGCAIAYELSAAGLSVVGIDAGDPAAGSTGAALGVLVGISSRQAGGETVQLRLKSLELFDPLIARLEEDLGRSL
PVNRRGILKLLREEEVEAWQETLVARRQAGYRLDLLSLAEVGSLQPGLRSDLAAAIYSPQDRQVQPKLLTQALLEAAQRK
GSRFFFHQPVQKIQRSSDPPFRLQTVYTPALTLSAGHVILAAGLGSSPLAKELGLQVPLQAVKGQALRVKAPGIPLGPVV
TDADLHLVPLGDGSLWVGATVEFQAPHPEPTLLALQDLLARAIRLCPALAAATLLDHWAGHRPRPVGQRAPILGWAPGYA
NLLIATGHYRNGVLLAPISAAILRDLVLKGETALCDLGPFAPRQG

Sequences:

>Translated_365_residues
MIGCGVVGCAIAYELSAAGLSVVGIDAGDPAAGSTGAALGVLVGISSRQAGGETVQLRLKSLELFDPLIARLEEDLGRSL
PVNRRGILKLLREEEVEAWQETLVARRQAGYRLDLLSLAEVGSLQPGLRSDLAAAIYSPQDRQVQPKLLTQALLEAAQRK
GSRFFFHQPVQKIQRSSDPPFRLQTVYTPALTLSAGHVILAAGLGSSPLAKELGLQVPLQAVKGQALRVKAPGIPLGPVV
TDADLHLVPLGDGSLWVGATVEFQAPHPEPTLLALQDLLARAIRLCPALAAATLLDHWAGHRPRPVGQRAPILGWAPGYA
NLLIATGHYRNGVLLAPISAAILRDLVLKGETALCDLGPFAPRQG
>Mature_365_residues
MIGCGVVGCAIAYELSAAGLSVVGIDAGDPAAGSTGAALGVLVGISSRQAGGETVQLRLKSLELFDPLIARLEEDLGRSL
PVNRRGILKLLREEEVEAWQETLVARRQAGYRLDLLSLAEVGSLQPGLRSDLAAAIYSPQDRQVQPKLLTQALLEAAQRK
GSRFFFHQPVQKIQRSSDPPFRLQTVYTPALTLSAGHVILAAGLGSSPLAKELGLQVPLQAVKGQALRVKAPGIPLGPVV
TDADLHLVPLGDGSLWVGATVEFQAPHPEPTLLALQDLLARAIRLCPALAAATLLDHWAGHRPRPVGQRAPILGWAPGYA
NLLIATGHYRNGVLLAPISAAILRDLVLKGETALCDLGPFAPRQG

Specific function: Catalyzes the FAD-dependent oxidative deamination of various amines and D-amino acids to yield the corresponding alpha- keto acids, ammonia/amine, and hydrogen peroxide. Oxidizes sarcosine (N-methylglycine), N-ethylglycine and glycine. Can also oxidize th

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAO family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=382, Percent_Identity=24.869109947644, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR012727 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.3.19 [H]

Molecular weight: Translated: 38522; Mature: 38522

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGCGVVGCAIAYELSAAGLSVVGIDAGDPAAGSTGAALGVLVGISSRQAGGETVQLRLK
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHEEECCCCCCCCCEEEEEHH
SLELFDPLIARLEEDLGRSLPVNRRGILKLLREEEVEAWQETLVARRQAGYRLDLLSLAE
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
VGSLQPGLRSDLAAAIYSPQDRQVQPKLLTQALLEAAQRKGSRFFFHQPVQKIQRSSDPP
HCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCC
FRLQTVYTPALTLSAGHVILAAGLGSSPLAKELGLQVPLQAVKGQALRVKAPGIPLGPVV
EEEEEEECCEEEECCCCEEEEECCCCCCHHHHHCCCCCHHHHCCCEEEEECCCCCCCCEE
TDADLHLVPLGDGSLWVGATVEFQAPHPEPTLLALQDLLARAIRLCPALAAATLLDHWAG
ECCCEEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HRPRPVGQRAPILGWAPGYANLLIATGHYRNGVLLAPISAAILRDLVLKGETALCDLGPF
CCCCCCCCCCCEEEECCCCCEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCEECCCCC
APRQG
CCCCC
>Mature Secondary Structure
MIGCGVVGCAIAYELSAAGLSVVGIDAGDPAAGSTGAALGVLVGISSRQAGGETVQLRLK
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHEEECCCCCCCCCEEEEEHH
SLELFDPLIARLEEDLGRSLPVNRRGILKLLREEEVEAWQETLVARRQAGYRLDLLSLAE
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHH
VGSLQPGLRSDLAAAIYSPQDRQVQPKLLTQALLEAAQRKGSRFFFHQPVQKIQRSSDPP
HCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCC
FRLQTVYTPALTLSAGHVILAAGLGSSPLAKELGLQVPLQAVKGQALRVKAPGIPLGPVV
EEEEEEECCEEEECCCCEEEEECCCCCCHHHHHCCCCCHHHHCCCEEEEECCCCCCCCEE
TDADLHLVPLGDGSLWVGATVEFQAPHPEPTLLALQDLLARAIRLCPALAAATLLDHWAG
ECCCEEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
HRPRPVGQRAPILGWAPGYANLLIATGHYRNGVLLAPISAAILRDLVLKGETALCDLGPF
CCCCCCCCCCCEEEECCCCCEEEEEECCCCCCEEECHHHHHHHHHHHHCCCCCEECCCCC
APRQG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9827558; 11744710 [H]