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The map label for this gene is mtaD [H]

Identifier: 86609001

GI number: 86609001

Start: 1611315

End: 1612730

Strand: Direct

Name: mtaD [H]

Synonym: CYB_1536

Alternate gene names: 86609001

Gene position: 1611315-1612730 (Clockwise)

Preceding gene: 86609000

Following gene: 86609002

Centisome position: 52.89

GC content: 61.58

Gene sequence:

>1416_bases
ATGAGTTTTATCTTGCGCAATGCGTTAATTCCCACCGCCACCGGCTACGAAACCGCAGATGTGCGAATCGAGGGGGAACG
GATTGCTGCCATAGGCAGAGGGTTACCCGCAACGGGCGCAGACAGCCTGGAACTGGATGCCAGTAACCAACTCTTGCTGC
CGGGCTTTGTCAATGCCCACACCCATTCTTCCGAAATGTGGCAACGAGGGATCATACCGCCCTATCCGCTGGAGCTGTGG
CTGGCACAACTGCACGAGTATGCGCCGCCGGATCCGGAAAAAATCTATCTCAGCGCGCTGGGGACGGCGGTGGAAACCCT
GCTGACGGGGGGCACCTCGGTGGTGGATCATCTGGTGTTGATCCCAGGCCAAGAGTTGGCCACCATTGAGGCGGCGGTAC
GGGCCTACCGAGAAGTCGGGATCCGCGCCTTCGTGGGCCCCTTGATCCAGGATCAGGCTCTCTCTCGGGGGTTGCCCAGC
AGCTCCTCTTGGGATCGGGAGCCGGAAACCTATCCCCTCTCCACAGCAGAGGTGCTGGCCATTGTGGAAGAGGCGGTGCA
GCGCTTTCACCGGCCAGAAGAGGGCATTACCCTCATGGTGGCTCCCACAGGGATCCAACTGTGCTCAGACGAGCTGTTCA
AGGGCTGTGCGGAGTTAAGCCAGAAGTATGACCTACCCCGCCACGCCCACCTGTTGGAAACCCGCGCCCAGCAGATGTTG
GCCCAGGAAAAGTACGGCTGCAGCGCAGTCGAGCATCTGGAGCGCCTGGGCTACCTAGACCAGAGAACTTCCCTGGCTCA
CTGCGTCTGGCTCAGCGATGCCGATATCGAGATCTTGGCCCGCACCGGCTCTACCGTTGTTCACAACCCCTTGAGCAACC
TGCGCCTAGGCAGCGGCATTGCCCCCATCTTGAAATACCGCCGGGCAGGGGTGAACGTGGCCTTTGGCTGCGATGGATCC
GCCAGCAACGATTCGCAGGATTTGCTAGAGGCCATCAAAATCGGCACCATCCTTCACAACATCACCGATCCCGACTACCG
CCACTGGATCTCGCCCCGCGAGAGTGTGGAGATGGCCTCCCGCGGTGGGGCCATTGGCCTGGGGCTAGGGGAGGAGCTGG
GATCCCTGGAAGTGGGCAAGCAAGCGGATCTGGTGCTGTACGATCTCACCCAACTGTCGCTGTTGCCCCGTACCGATCCC
ATTGGGCTGCTGGTGTTGGGCCGGCCCACCCAGGCAGTCCACAGCGTCTGGGTGCGAGGAAAACAGGTGGTGTCCGGCGG
AGCCGTGACGACGGTGGATGTGGCTAATCTGCGACAGGAGTTGTTTGCTTGTAGCTCCTGGGATCCCTCCCGCCGCTCCC
AGCAGGTGGCACAGCTGGAGGCCCGCTACCGCCGCGTGATGGGTTTGCCGGCATAG

Upstream 100 bases:

>100_bases
GGAAAGGCTAGGTTATGCATGCAAATGTTCTGATCCTCCCGCCTTGGCAGGGTTAACTCCAGCACGCTAAGGTAGCAGAC
GGCCTTTTTGGATCCCGGGC

Downstream 100 bases:

>100_bases
CCATGGCAGGGATCCCTGCGGGTTCAGAGGTCGACTGGTCCAGAGCCACTGCGCAGGTGAAACGACAGGCCCTGGCCCTG
GGTTTTGACAAAGTCGGCAT

Product: amidohydrolase family protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSFILRNALIPTATGYETADVRIEGERIAAIGRGLPATGADSLELDASNQLLLPGFVNAHTHSSEMWQRGIIPPYPLELW
LAQLHEYAPPDPEKIYLSALGTAVETLLTGGTSVVDHLVLIPGQELATIEAAVRAYREVGIRAFVGPLIQDQALSRGLPS
SSSWDREPETYPLSTAEVLAIVEEAVQRFHRPEEGITLMVAPTGIQLCSDELFKGCAELSQKYDLPRHAHLLETRAQQML
AQEKYGCSAVEHLERLGYLDQRTSLAHCVWLSDADIEILARTGSTVVHNPLSNLRLGSGIAPILKYRRAGVNVAFGCDGS
ASNDSQDLLEAIKIGTILHNITDPDYRHWISPRESVEMASRGGAIGLGLGEELGSLEVGKQADLVLYDLTQLSLLPRTDP
IGLLVLGRPTQAVHSVWVRGKQVVSGGAVTTVDVANLRQELFACSSWDPSRRSQQVAQLEARYRRVMGLPA

Sequences:

>Translated_471_residues
MSFILRNALIPTATGYETADVRIEGERIAAIGRGLPATGADSLELDASNQLLLPGFVNAHTHSSEMWQRGIIPPYPLELW
LAQLHEYAPPDPEKIYLSALGTAVETLLTGGTSVVDHLVLIPGQELATIEAAVRAYREVGIRAFVGPLIQDQALSRGLPS
SSSWDREPETYPLSTAEVLAIVEEAVQRFHRPEEGITLMVAPTGIQLCSDELFKGCAELSQKYDLPRHAHLLETRAQQML
AQEKYGCSAVEHLERLGYLDQRTSLAHCVWLSDADIEILARTGSTVVHNPLSNLRLGSGIAPILKYRRAGVNVAFGCDGS
ASNDSQDLLEAIKIGTILHNITDPDYRHWISPRESVEMASRGGAIGLGLGEELGSLEVGKQADLVLYDLTQLSLLPRTDP
IGLLVLGRPTQAVHSVWVRGKQVVSGGAVTTVDVANLRQELFACSSWDPSRRSQQVAQLEARYRRVMGLPA
>Mature_470_residues
SFILRNALIPTATGYETADVRIEGERIAAIGRGLPATGADSLELDASNQLLLPGFVNAHTHSSEMWQRGIIPPYPLELWL
AQLHEYAPPDPEKIYLSALGTAVETLLTGGTSVVDHLVLIPGQELATIEAAVRAYREVGIRAFVGPLIQDQALSRGLPSS
SSWDREPETYPLSTAEVLAIVEEAVQRFHRPEEGITLMVAPTGIQLCSDELFKGCAELSQKYDLPRHAHLLETRAQQMLA
QEKYGCSAVEHLERLGYLDQRTSLAHCVWLSDADIEILARTGSTVVHNPLSNLRLGSGIAPILKYRRAGVNVAFGCDGSA
SNDSQDLLEAIKIGTILHNITDPDYRHWISPRESVEMASRGGAIGLGLGEELGSLEVGKQADLVLYDLTQLSLLPRTDPI
GLLVLGRPTQAVHSVWVRGKQVVSGGAVTTVDVANLRQELFACSSWDPSRRSQQVAQLEARYRRVMGLPA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=406, Percent_Identity=25.1231527093596, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI87082177, Length=453, Percent_Identity=26.4900662251656, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789249, Length=365, Percent_Identity=27.9452054794521, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540282, Length=394, Percent_Identity=24.3654822335025, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319963, Length=396, Percent_Identity=23.989898989899, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24643849, Length=407, Percent_Identity=26.2899262899263, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 51278; Mature: 51147

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFILRNALIPTATGYETADVRIEGERIAAIGRGLPATGADSLELDASNQLLLPGFVNAH
CCCHHHHCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCEEECCCCCEECCCCCCCC
THSSEMWQRGIIPPYPLELWLAQLHEYAPPDPEKIYLSALGTAVETLLTGGTSVVDHLVL
CCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEE
IPGQELATIEAAVRAYREVGIRAFVGPLIQDQALSRGLPSSSSWDREPETYPLSTAEVLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
IVEEAVQRFHRPEEGITLMVAPTGIQLCSDELFKGCAELSQKYDLPRHAHLLETRAQQML
HHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AQEKYGCSAVEHLERLGYLDQRTSLAHCVWLSDADIEILARTGSTVVHNPLSNLRLGSGI
HHHHCCCHHHHHHHHCCCHHHCCCCEEEEEECCCCEEEEEECCCHHEECCHHHCCCCCCH
APILKYRRAGVNVAFGCDGSASNDSQDLLEAIKIGTILHNITDPDYRHWISPRESVEMAS
HHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHH
RGGAIGLGLGEELGSLEVGKQADLVLYDLTQLSLLPRTDPIGLLVLGRPTQAVHSVWVRG
CCCEEEECCCHHCCCCCCCCCCCEEEEEHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCC
KQVVSGGAVTTVDVANLRQELFACSSWDPSRRSQQVAQLEARYRRVMGLPA
HHEECCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFILRNALIPTATGYETADVRIEGERIAAIGRGLPATGADSLELDASNQLLLPGFVNAH
CCHHHHCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCEEECCCCCEECCCCCCCC
THSSEMWQRGIIPPYPLELWLAQLHEYAPPDPEKIYLSALGTAVETLLTGGTSVVDHLVL
CCCHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHEE
IPGQELATIEAAVRAYREVGIRAFVGPLIQDQALSRGLPSSSSWDREPETYPLSTAEVLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHH
IVEEAVQRFHRPEEGITLMVAPTGIQLCSDELFKGCAELSQKYDLPRHAHLLETRAQQML
HHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AQEKYGCSAVEHLERLGYLDQRTSLAHCVWLSDADIEILARTGSTVVHNPLSNLRLGSGI
HHHHCCCHHHHHHHHCCCHHHCCCCEEEEEECCCCEEEEEECCCHHEECCHHHCCCCCCH
APILKYRRAGVNVAFGCDGSASNDSQDLLEAIKIGTILHNITDPDYRHWISPRESVEMAS
HHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHH
RGGAIGLGLGEELGSLEVGKQADLVLYDLTQLSLLPRTDPIGLLVLGRPTQAVHSVWVRG
CCCEEEECCCHHCCCCCCCCCCCEEEEEHHHHHHCCCCCCCEEEEECCCHHHHHHHHHCC
KQVVSGGAVTTVDVANLRQELFACSSWDPSRRSQQVAQLEARYRRVMGLPA
HHEECCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA