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The map label for this gene is ppx [H]

Identifier: 86608960

GI number: 86608960

Start: 1568892

End: 1570619

Strand: Direct

Name: ppx [H]

Synonym: CYB_1493

Alternate gene names: 86608960

Gene position: 1568892-1570619 (Clockwise)

Preceding gene: 86608956

Following gene: 86608962

Centisome position: 51.5

GC content: 61.92

Gene sequence:

>1728_bases
ATGATCTCTTCGCCCACCAACTTCACGGAATGCCCTGTCGCCTCTGCTCCCCCAGTTTCCGAAACCGGCCCGGCTTCTCG
TCCTGAATCTTGGGCTGCCCCCGTTCTGGCGGCCATCGATGTGGGCAGCAACTCTCTCCACATGGTGGTGGTGCGCATCA
ATCCCCGTATCCCCAGCTTCACCATCATCTCCCGCGAAAAAGCCACCGTCCGGCTGGGGGAGTTTTGCAGCCAGACGGGC
GCCCTCACGCCTGCAGCTATGGAACGGGCCCGGACGGCTCTGGAGCGGTTTTGCCGCATTGCTGAGAGCTTTCAGGTGCA
GGATATTGTTGCCGTGGCTACCAGTGCTGTGCGCGAGGCCCCCAATGGGCTGGAGTTTTTGAAGCGGATTGAACGGGAGC
TGGGCCTGCGGGTGGAGTTAATCTCGGGGCAGGAAGAGGCCCGCCGCATCTACCTGGGGGTGCTCTCGGCGATGGAGTTC
CACAACCGGCTGCACGCGGTGGTGGATATTGGTGGCGGCTCCACCGAGCTGATTTTGGGCAATGGCCAAGAGCCGGAGTT
TCTGCGCAGCGTCAAGGTAGGGGCAGTGCGTCTGACCCAGGCTTTTTTGCACCACGACCCGCCCACTTCTGGCGAACTGC
AAGCCCTGCGCCAGCACATCCGCGGCATGCTGGAATCCCCCATCGAGCAGATGAAGCGGATCCTTGCCTCTTCACAACAA
CAGGGATCCCTGCCTTTGGTGGGCACCTCTGGCACCGTCGAGTGCCTGGCCCAGTTGGATGCCCGCCGTCGGTTGGGCGC
TCTCCCCCATCGCCTGCAGGGGTATGAGTTCAGCCTGGAAGCCCTGCGCGGCTACATCAAAGAGCTGCGCTCCCTCACGG
TGGCCGAACGGCAAAAGCTGCCCGGCCTGGGGGAAAGGCGGGGGGAGATCATCCTAGCCGGGGCGGTCATCTTGGAAGAA
GTGATGACCCTGCTGGGGGTGGAGCGGATCCAGTTTTGCGAACGGGCTCTGCGGGAAGGGCTGATCGTGGACTGGATGAT
CGGCCAAGGGCTGATTGAGGATCGGCTGCGCTACCACAGCTCGGTGCGGCGGCGCAGTGTGCTCAAGCTGGCGGAAAAAT
ACCAGGTGGAGATCCCCTATGCCGAGCGGGTGGCCGAGTTTGCCCTCAGCCTTTTCGATCAAACCCGCGGCATCCTGCAT
GGCTGGGGATCCCGGGAGCGGGCTCTTCTCTGGGCGGCGGCCATGCTGCACAACTGCGGCCACTTCATCAGCCATGCCGC
CCACCACAAGCACTCCTACTACCTGATCCGCCATGGAGAACTCTTGGGCTTCAACGAAGAAGAGGTGGAGGTGATCGCCA
ACTTGGCCCGCTACCACCGCAAGTCGCCCCCCAAGAAGAAGCACGAGAACTTCCAGCGCCTCAGCGACGAGCGGGATCGC
CAAGTGGTGCTGGAACTGAGCCCCCTGCTGCGCATAGCCTGTGCTTTGGATCGCCGCCGCCTGCAGGCCATTCAAGCCCT
GCACTGCCGTTTTCAGCTCCTGGGAGAAGGCCCCCGCCGCATGGAGTTGATTTTGGATCCCAGGCATCCCAAGGACGACT
GTGCCCTAGAGTTGTGGAGCTTAAACGAGAAGAAAAAAGTCTTCGAGCAACAGTTCAACCTGCAGGTAATCCCCAAGCTC
TCTACGCAGATCCAGCGCAGCGCCGATCCCTTTGAGGCAGCAGTTTAG

Upstream 100 bases:

>100_bases
TGTTTGCCGAGTCAACCGCGAACCTCACCTCACGACTCGGCCCGGAACAAGGGGGGAAAGTACACAGTATCCTAAAGGGG
TTGACCCCCACACCCGAGCC

Downstream 100 bases:

>100_bases
CCTTCTCGGGGATCCTAGCTAAGGGGCGATGGTAATGGGCGAGGGGCTGGTTTGGGTGGTCTTTTGGCCCCCTCTTTGCA
AAATCACCTCGATGATGCCG

Product: exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MISSPTNFTECPVASAPPVSETGPASRPESWAAPVLAAIDVGSNSLHMVVVRINPRIPSFTIISREKATVRLGEFCSQTG
ALTPAAMERARTALERFCRIAESFQVQDIVAVATSAVREAPNGLEFLKRIERELGLRVELISGQEEARRIYLGVLSAMEF
HNRLHAVVDIGGGSTELILGNGQEPEFLRSVKVGAVRLTQAFLHHDPPTSGELQALRQHIRGMLESPIEQMKRILASSQQ
QGSLPLVGTSGTVECLAQLDARRRLGALPHRLQGYEFSLEALRGYIKELRSLTVAERQKLPGLGERRGEIILAGAVILEE
VMTLLGVERIQFCERALREGLIVDWMIGQGLIEDRLRYHSSVRRRSVLKLAEKYQVEIPYAERVAEFALSLFDQTRGILH
GWGSRERALLWAAAMLHNCGHFISHAAHHKHSYYLIRHGELLGFNEEEVEVIANLARYHRKSPPKKKHENFQRLSDERDR
QVVLELSPLLRIACALDRRRLQAIQALHCRFQLLGEGPRRMELILDPRHPKDDCALELWSLNEKKKVFEQQFNLQVIPKL
STQIQRSADPFEAAV

Sequences:

>Translated_575_residues
MISSPTNFTECPVASAPPVSETGPASRPESWAAPVLAAIDVGSNSLHMVVVRINPRIPSFTIISREKATVRLGEFCSQTG
ALTPAAMERARTALERFCRIAESFQVQDIVAVATSAVREAPNGLEFLKRIERELGLRVELISGQEEARRIYLGVLSAMEF
HNRLHAVVDIGGGSTELILGNGQEPEFLRSVKVGAVRLTQAFLHHDPPTSGELQALRQHIRGMLESPIEQMKRILASSQQ
QGSLPLVGTSGTVECLAQLDARRRLGALPHRLQGYEFSLEALRGYIKELRSLTVAERQKLPGLGERRGEIILAGAVILEE
VMTLLGVERIQFCERALREGLIVDWMIGQGLIEDRLRYHSSVRRRSVLKLAEKYQVEIPYAERVAEFALSLFDQTRGILH
GWGSRERALLWAAAMLHNCGHFISHAAHHKHSYYLIRHGELLGFNEEEVEVIANLARYHRKSPPKKKHENFQRLSDERDR
QVVLELSPLLRIACALDRRRLQAIQALHCRFQLLGEGPRRMELILDPRHPKDDCALELWSLNEKKKVFEQQFNLQVIPKL
STQIQRSADPFEAAV
>Mature_575_residues
MISSPTNFTECPVASAPPVSETGPASRPESWAAPVLAAIDVGSNSLHMVVVRINPRIPSFTIISREKATVRLGEFCSQTG
ALTPAAMERARTALERFCRIAESFQVQDIVAVATSAVREAPNGLEFLKRIERELGLRVELISGQEEARRIYLGVLSAMEF
HNRLHAVVDIGGGSTELILGNGQEPEFLRSVKVGAVRLTQAFLHHDPPTSGELQALRQHIRGMLESPIEQMKRILASSQQ
QGSLPLVGTSGTVECLAQLDARRRLGALPHRLQGYEFSLEALRGYIKELRSLTVAERQKLPGLGERRGEIILAGAVILEE
VMTLLGVERIQFCERALREGLIVDWMIGQGLIEDRLRYHSSVRRRSVLKLAEKYQVEIPYAERVAEFALSLFDQTRGILH
GWGSRERALLWAAAMLHNCGHFISHAAHHKHSYYLIRHGELLGFNEEEVEVIANLARYHRKSPPKKKHENFQRLSDERDR
QVVLELSPLLRIACALDRRRLQAIQALHCRFQLLGEGPRRMELILDPRHPKDDCALELWSLNEKKKVFEQQFNLQVIPKL
STQIQRSADPFEAAV

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=491, Percent_Identity=32.3828920570265, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI48994966, Length=470, Percent_Identity=28.936170212766, Blast_Score=148, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 64688; Mature: 64688

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSPTNFTECPVASAPPVSETGPASRPESWAAPVLAAIDVGSNSLHMVVVRINPRIPSF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCHHHEEEECCCCCEEEEEEEECCCCCCE
TIISREKATVRLGEFCSQTGALTPAAMERARTALERFCRIAESFQVQDIVAVATSAVREA
EEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNGLEFLKRIERELGLRVELISGQEEARRIYLGVLSAMEFHNRLHAVVDIGGGSTELILG
CCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEC
NGQEPEFLRSVKVGAVRLTQAFLHHDPPTSGELQALRQHIRGMLESPIEQMKRILASSQQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QGSLPLVGTSGTVECLAQLDARRRLGALPHRLQGYEFSLEALRGYIKELRSLTVAERQKL
CCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PGLGERRGEIILAGAVILEEVMTLLGVERIQFCERALREGLIVDWMIGQGLIEDRLRYHS
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHHH
SVRRRSVLKLAEKYQVEIPYAERVAEFALSLFDQTRGILHGWGSRERALLWAAAMLHNCG
HHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HFISHAAHHKHSYYLIRHGELLGFNEEEVEVIANLARYHRKSPPKKKHENFQRLSDERDR
HHHHHHHHCCCCEEEEECCCEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
QVVLELSPLLRIACALDRRRLQAIQALHCRFQLLGEGPRRMELILDPRHPKDDCALELWS
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHEEHHC
LNEKKKVFEQQFNLQVIPKLSTQIQRSADPFEAAV
CCHHHHHHHHHCCEEEECHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MISSPTNFTECPVASAPPVSETGPASRPESWAAPVLAAIDVGSNSLHMVVVRINPRIPSF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCHHHEEEECCCCCEEEEEEEECCCCCCE
TIISREKATVRLGEFCSQTGALTPAAMERARTALERFCRIAESFQVQDIVAVATSAVREA
EEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PNGLEFLKRIERELGLRVELISGQEEARRIYLGVLSAMEFHNRLHAVVDIGGGSTELILG
CCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEC
NGQEPEFLRSVKVGAVRLTQAFLHHDPPTSGELQALRQHIRGMLESPIEQMKRILASSQQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QGSLPLVGTSGTVECLAQLDARRRLGALPHRLQGYEFSLEALRGYIKELRSLTVAERQKL
CCCCCEEECCHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PGLGERRGEIILAGAVILEEVMTLLGVERIQFCERALREGLIVDWMIGQGLIEDRLRYHS
CCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHHH
SVRRRSVLKLAEKYQVEIPYAERVAEFALSLFDQTRGILHGWGSRERALLWAAAMLHNCG
HHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HFISHAAHHKHSYYLIRHGELLGFNEEEVEVIANLARYHRKSPPKKKHENFQRLSDERDR
HHHHHHHHCCCCEEEEECCCEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHH
QVVLELSPLLRIACALDRRRLQAIQALHCRFQLLGEGPRRMELILDPRHPKDDCALELWS
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHEEHHC
LNEKKKVFEQQFNLQVIPKLSTQIQRSADPFEAAV
CCHHHHHHHHHCCEEEECHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]