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The map label for this gene is cysC

Identifier: 86608885

GI number: 86608885

Start: 1485677

End: 1486204

Strand: Reverse

Name: cysC

Synonym: CYB_1417

Alternate gene names: 86608885

Gene position: 1486204-1485677 (Counterclockwise)

Preceding gene: 86608887

Following gene: 86608884

Centisome position: 48.78

GC content: 59.47

Gene sequence:

>528_bases
ATGTCGCGGCGGGGGGTAACGGTCTGGTTTACGGGATTGAGCGGGGCGGGCAAAACCACCCTGAGCTGCGGCGTGGCCCA
GCAGTTGCGCGCTTGGGGGCTGCCGGTGGAAGTGCTCGATGGGGACCTGGTGCGGCAACATCTCACCAAGGGTCTGGGCT
TCAGCAAAGTGGATCGGGAGGAGAACATTCGCCGCATCGGCTTTGTGGCGGAGATGCTGACTCGGCACGGGGTGATTGTG
CTGGTGTCGGCCATTTCCCCCTATCGGGCAGCACGGCAGGAGGTACGGCGATATATTGGCAGCTTCATCGAGGTCTTTGT
GGATGCCCCTTTGGAGGTGTGCGAACGCCGGGATGTGAAGGGCCTCTATCGAAAGGCGCGGGCAGGCTTAATCCAGCACT
TTACCGGTATTGACGATCCCTACGAGCCGCCGGAACAGCCGGAGGTGGTGTGCAAAACTGCCGAGCAAAGCATCCCCGAA
TGTATTGACCTGGTGATACAAAGCCTAAAAAGCAGAGGTTATGTCTAA

Upstream 100 bases:

>100_bases
CAAGCCGTGTTTCGAGTGTACCACCCTGCTTTGGAGATGATATTCTGGCGGGGCCAAAGATTCAGGGATCCACAGCAAAC
AGACAGAAGCAAACAGACAG

Downstream 100 bases:

>100_bases
CAGGCCCCCTGCTCTTACGTTGCCCGTAGAGGGTGGGCTTCCCCCCGGAGTAGCTGCAAAGAACCTAGAATTAAGAAAGG
CTTACAAGCAACTCCTATGG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MSRRGVTVWFTGLSGAGKTTLSCGVAQQLRAWGLPVEVLDGDLVRQHLTKGLGFSKVDREENIRRIGFVAEMLTRHGVIV
LVSAISPYRAARQEVRRYIGSFIEVFVDAPLEVCERRDVKGLYRKARAGLIQHFTGIDDPYEPPEQPEVVCKTAEQSIPE
CIDLVIQSLKSRGYV

Sequences:

>Translated_175_residues
MSRRGVTVWFTGLSGAGKTTLSCGVAQQLRAWGLPVEVLDGDLVRQHLTKGLGFSKVDREENIRRIGFVAEMLTRHGVIV
LVSAISPYRAARQEVRRYIGSFIEVFVDAPLEVCERRDVKGLYRKARAGLIQHFTGIDDPYEPPEQPEVVCKTAEQSIPE
CIDLVIQSLKSRGYV
>Mature_174_residues
SRRGVTVWFTGLSGAGKTTLSCGVAQQLRAWGLPVEVLDGDLVRQHLTKGLGFSKVDREENIRRIGFVAEMLTRHGVIVL
VSAISPYRAARQEVRRYIGSFIEVFVDAPLEVCERRDVKGLYRKARAGLIQHFTGIDDPYEPPEQPEVVCKTAEQSIPEC
IDLVIQSLKSRGYV

Specific function: Catalyzes the synthesis of activated sulfate

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family

Homologues:

Organism=Homo sapiens, GI46094058, Length=176, Percent_Identity=53.4090909090909, Blast_Score=181, Evalue=3e-46,
Organism=Homo sapiens, GI62912492, Length=176, Percent_Identity=50, Blast_Score=173, Evalue=6e-44,
Organism=Homo sapiens, GI34447231, Length=176, Percent_Identity=50, Blast_Score=173, Evalue=7e-44,
Organism=Escherichia coli, GI1789107, Length=175, Percent_Identity=48, Blast_Score=167, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17542422, Length=176, Percent_Identity=48.8636363636364, Blast_Score=170, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322852, Length=171, Percent_Identity=47.3684210526316, Blast_Score=159, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667032, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24667028, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24667036, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24667040, Length=176, Percent_Identity=46.0227272727273, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI116007838, Length=176, Percent_Identity=46.0227272727273, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24667044, Length=176, Percent_Identity=46.0227272727273, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSC_SYNJB (Q2JLM3)

Other databases:

- EMBL:   CP000240
- RefSeq:   YP_477647.1
- ProteinModelPortal:   Q2JLM3
- SMR:   Q2JLM3
- STRING:   Q2JLM3
- GeneID:   3901321
- GenomeReviews:   CP000240_GR
- KEGG:   cyb:CYB_1417
- TIGR:   CYB_1417
- eggNOG:   COG0529
- HOGENOM:   HBG309946
- OMA:   ITITAFV
- PhylomeDB:   Q2JLM3
- ProtClustDB:   PRK00889
- BioCyc:   SSP321332:CYB_1417-MONOMER
- HAMAP:   MF_00065
- InterPro:   IPR002891
- TIGRFAMs:   TIGR00455

Pfam domain/function: PF01583 APS_kinase

EC number: =2.7.1.25

Molecular weight: Translated: 19543; Mature: 19412

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: ACT_SITE 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRGVTVWFTGLSGAGKTTLSCGVAQQLRAWGLPVEVLDGDLVRQHLTKGLGFSKVDRE
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHCHH
ENIRRIGFVAEMLTRHGVIVLVSAISPYRAARQEVRRYIGSFIEVFVDAPLEVCERRDVK
HHHHHHHHHHHHHHHCCHHEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHH
GLYRKARAGLIQHFTGIDDPYEPPEQPEVVCKTAEQSIPECIDLVIQSLKSRGYV
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRRGVTVWFTGLSGAGKTTLSCGVAQQLRAWGLPVEVLDGDLVRQHLTKGLGFSKVDRE
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHCHH
ENIRRIGFVAEMLTRHGVIVLVSAISPYRAARQEVRRYIGSFIEVFVDAPLEVCERRDVK
HHHHHHHHHHHHHHHCCHHEEHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHH
GLYRKARAGLIQHFTGIDDPYEPPEQPEVVCKTAEQSIPECIDLVIQSLKSRGYV
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA