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The map label for this gene is sasA [H]

Identifier: 86608818

GI number: 86608818

Start: 1412287

End: 1413045

Strand: Reverse

Name: sasA [H]

Synonym: CYB_1344

Alternate gene names: 86608818

Gene position: 1413045-1412287 (Counterclockwise)

Preceding gene: 86608819

Following gene: 86608817

Centisome position: 46.38

GC content: 60.21

Gene sequence:

>759_bases
ATGCCGAGAGCCAGAAAAGTTGCTGAACACCATCCAGAGCCTGAACCCGTCTGCGGAGCCGGAGAACCCAAGGTTAAGGG
GGTCACTCTTTCTGCCCAGCAGCTTTCCACTTTGCTTCACGAAATGCGCAATCCTCTCACCGCCCTGAGCACGCTGGCCA
AGTTATTGCAAAAACGCTTGCCCCCCGAGGATCGCAACCACTGGATTGGCCTGAGCATTGAACAGGAGTGCAAGCATTTG
CAGGAGCTGCTCGCGGAGTTCGAGCGTTTGGACGGGATCCCGGCCCCCCTCCAGCTTCAGCCCCTCTCCTTGGCCGACCT
GCTGCGGGAGTGGATCCCCATCTATCAAGCCTTGGCCGAAACCCAGGGACACCACTTTCAAGCCGTTCTGCCCCCTTCCC
TACCCCCTGTACAAGCCGATCCGCGCGCCCTGCGCCAGGTGCTTGATAACCTGATCGACAACGCTTGCAAGTACACCCCG
CCCCCAGGTGAGATCCGGCTGAAGGTGGAGCTGGGTGAAGATCCCTCAACTGCTTCGCAACGGGAAGTGTTCGTTGCCGT
CTGCGACAACGGCCCCGGCATCCACCCTGAGAACCTGGAGCGGATCTTCGATCCCTTTTTTCGGGCAGATCTTTCTAAGC
CAGGGCAGGGGCTGGGGTTGGCCATTAGCCGCGACCTGGCCACCCGGATGGGCGGAGATCTCCAGGTGGAAAGCTCCCCC
CAAGGCTCCTGTTTTCGCCTGAGATTGCCCACAGGTTAG

Upstream 100 bases:

>100_bases
TTGGGATCCCGATAGCGTCTCAGGATTGATATGGCGGATTGCAGGGGAGGTAGGGCTAGGATCGATCTGCCAGCGCCGGG
AGAGTCTAGGGATTGGATCC

Downstream 100 bases:

>100_bases
TAGGAAGATTGTAGAGATATGGGATGGCAGGTGCCGCCAAACGCTTGAACGCTACCCAGGAGCTGCAGATGGCCTCTTCT
CCCCCAGCCAAACCCGAACC

Product: sensor histidine kinase

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MPRARKVAEHHPEPEPVCGAGEPKVKGVTLSAQQLSTLLHEMRNPLTALSTLAKLLQKRLPPEDRNHWIGLSIEQECKHL
QELLAEFERLDGIPAPLQLQPLSLADLLREWIPIYQALAETQGHHFQAVLPPSLPPVQADPRALRQVLDNLIDNACKYTP
PPGEIRLKVELGEDPSTASQREVFVAVCDNGPGIHPENLERIFDPFFRADLSKPGQGLGLAISRDLATRMGGDLQVESSP
QGSCFRLRLPTG

Sequences:

>Translated_252_residues
MPRARKVAEHHPEPEPVCGAGEPKVKGVTLSAQQLSTLLHEMRNPLTALSTLAKLLQKRLPPEDRNHWIGLSIEQECKHL
QELLAEFERLDGIPAPLQLQPLSLADLLREWIPIYQALAETQGHHFQAVLPPSLPPVQADPRALRQVLDNLIDNACKYTP
PPGEIRLKVELGEDPSTASQREVFVAVCDNGPGIHPENLERIFDPFFRADLSKPGQGLGLAISRDLATRMGGDLQVESSP
QGSCFRLRLPTG
>Mature_251_residues
PRARKVAEHHPEPEPVCGAGEPKVKGVTLSAQQLSTLLHEMRNPLTALSTLAKLLQKRLPPEDRNHWIGLSIEQECKHLQ
ELLAEFERLDGIPAPLQLQPLSLADLLREWIPIYQALAETQGHHFQAVLPPSLPPVQADPRALRQVLDNLIDNACKYTPP
PGEIRLKVELGEDPSTASQREVFVAVCDNGPGIHPENLERIFDPFFRADLSKPGQGLGLAISRDLATRMGGDLQVESSPQ
GSCFRLRLPTG

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=213, Percent_Identity=31.924882629108, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=32.7272727272727, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790346, Length=260, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=30.5309734513274, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=112, Percent_Identity=44.6428571428571, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=30.5309734513274, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=29.5081967213115, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=30.1724137931034, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=30.3030303030303, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=28.8888888888889, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=30.1724137931034, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=268, Percent_Identity=29.1044776119403, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789808, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=28.3842794759825, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=217, Percent_Identity=30.4147465437788, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788393, Length=222, Percent_Identity=26.1261261261261, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787374, Length=211, Percent_Identity=26.0663507109005, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 27824; Mature: 27693

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRARKVAEHHPEPEPVCGAGEPKVKGVTLSAQQLSTLLHEMRNPLTALSTLAKLLQKRL
CCCCCCHHHHCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
PPEDRNHWIGLSIEQECKHLQELLAEFERLDGIPAPLQLQPLSLADLLREWIPIYQALAE
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHH
TQGHHFQAVLPPSLPPVQADPRALRQVLDNLIDNACKYTPPPGEIRLKVELGEDPSTASQ
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
REVFVAVCDNGPGIHPENLERIFDPFFRADLSKPGQGLGLAISRDLATRMGGDLQVESSP
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCEEECCCC
QGSCFRLRLPTG
CCCEEEEECCCC
>Mature Secondary Structure 
PRARKVAEHHPEPEPVCGAGEPKVKGVTLSAQQLSTLLHEMRNPLTALSTLAKLLQKRL
CCCCCHHHHCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
PPEDRNHWIGLSIEQECKHLQELLAEFERLDGIPAPLQLQPLSLADLLREWIPIYQALAE
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHHHHHHHH
TQGHHFQAVLPPSLPPVQADPRALRQVLDNLIDNACKYTPPPGEIRLKVELGEDPSTASQ
CCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
REVFVAVCDNGPGIHPENLERIFDPFFRADLSKPGQGLGLAISRDLATRMGGDLQVESSP
CEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHCCCCEEECCCC
QGSCFRLRLPTG
CCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA