Click here to switch to the map view.

The map label for this gene is aroA [H]

Identifier: 86608800

GI number: 86608800

Start: 1387469

End: 1388773

Strand: Reverse

Name: aroA [H]

Synonym: CYB_1326

Alternate gene names: 86608800

Gene position: 1388773-1387469 (Counterclockwise)

Preceding gene: 86608815

Following gene: 86608799

Centisome position: 45.58

GC content: 64.06

Gene sequence:

>1305_bases
TTGACCCTCTCGCCGGCCAAGGGCCTGCGCGGCCAAGTGAGCATCCCCGGCGACAAATCCATTTCCCACCGCGCCCTGAT
GCTGGGATCCCTGGCCGAAGGAGAAACCACCATCCAAGGGCTGTTGCTGGGAGAGGATCCCCGCAGTACGGCAGCCTGCT
TTCGGGCGCTGGGGGCAGATATTTCGGAGCTCAACAGCGAGTGTGTTCGCATTCGGGGAGTTGGCCTGGGCCAGCTGCAA
GAACCGGCAGACGTGTTGGATGCCGGCAACTCCGGCACCACCCTGCGACTGATGCTGGGGATCCTGGCTGGCCAGGCCGG
GCGCTTTTTTGCCGTCACCGGCGATCGCTCCCTGCGCTCGCGGCCCATGGGGCGGGTGGTAGAACCGCTGCGGCAGATGG
GGGCCAGCATTTGGGGACGGGCCGGTGGGACGTTGGCACCTTTGGCCGTACAAGGGGGATCCCTCAAGGGCATTCACTAC
CGCTCCCCGGTGGCTTCAGCGCAGGTAAAATCCTGCCTCTTGCTGGCGGGTCTGCTGGCGGAAGGCACCACCCAAGTCAC
CGAGCCGGCTCTCTCTCGGGATCACTCGGAACGGATGTTGCGGGCCTTCGGGGCCAACATTCAGGTGGATCCGGAAACAA
AAACCGTGGCCGTGGTGGGGGGATCCCGCCTGGTGGGCCAGAGAGTTCAGGTGCCGGGGGATATCAGCTCGGCAGCCTTT
TGGCTGGTGGCCGTCTCCATTGTGCCCGAGAGCGAATTGCTGCTAAGGGATGTGGGCCTCAACCCCACCCGTACCGGTGC
ACTACGGGTGTTGCAGGAGATGGGGGCTGACATCCAAATTGAGAACCTCCGGGAAATGGCCGGTGAGCCCCTGGGAGATC
TGCGGGTGCGTTCGGCCCGCTTGCGCGGCTGCACCATCGCCGGCGATCTCATCCCCACCTTGATCGACGAGATCCCAGTT
TTGGCGGTGGCGGCTGCCTTTGCCGAAGGGATCACGGTGATTCGCGATGCCGCAGAGCTGCGGGTGAAAGAAAGCGACCG
CCTGTCAGCCATGGCCCAAGAGTTGAGCCGCATGGGAGCCCAGGTCGCCGAATATCCCGATGGCCTGGAAATCAAAGGAG
GGATCCCTCTTCACGGGGCCGAGGTCGACAGCCACGAGGATCACCGCATCGCCATGAGCCTGATGGTGGCAGCTCTAGGA
GCGCAGGGATCCACCCTCCTCAGGGGAGCCGACTGTGCCCGCATCTCCTACCCCGACTTCATTCCCACCCTGCAACGATT
GACTGCTTCCCCCCTGGAGTCTTGA

Upstream 100 bases:

>100_bases
GGGGCGCGAGTCCCGCTCTGAGTAAGATGAGACTGCTGCCGCTTTTGCCCAGTCTGCCATCAGAGTTGCTGTGTTGACTC
ACTCTTCTGCTACTGATATC

Downstream 100 bases:

>100_bases
GAGGGCCCATCTTTAACTTTGCCGCCTCTGCTCCTATGTCGACCTGCCCCAGCCCGCCCGGCCCTATCGCCATCGAACAT
CTCTGCTTCCGGGTTCCTCC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MTLSPAKGLRGQVSIPGDKSISHRALMLGSLAEGETTIQGLLLGEDPRSTAACFRALGADISELNSECVRIRGVGLGQLQ
EPADVLDAGNSGTTLRLMLGILAGQAGRFFAVTGDRSLRSRPMGRVVEPLRQMGASIWGRAGGTLAPLAVQGGSLKGIHY
RSPVASAQVKSCLLLAGLLAEGTTQVTEPALSRDHSERMLRAFGANIQVDPETKTVAVVGGSRLVGQRVQVPGDISSAAF
WLVAVSIVPESELLLRDVGLNPTRTGALRVLQEMGADIQIENLREMAGEPLGDLRVRSARLRGCTIAGDLIPTLIDEIPV
LAVAAAFAEGITVIRDAAELRVKESDRLSAMAQELSRMGAQVAEYPDGLEIKGGIPLHGAEVDSHEDHRIAMSLMVAALG
AQGSTLLRGADCARISYPDFIPTLQRLTASPLES

Sequences:

>Translated_434_residues
MTLSPAKGLRGQVSIPGDKSISHRALMLGSLAEGETTIQGLLLGEDPRSTAACFRALGADISELNSECVRIRGVGLGQLQ
EPADVLDAGNSGTTLRLMLGILAGQAGRFFAVTGDRSLRSRPMGRVVEPLRQMGASIWGRAGGTLAPLAVQGGSLKGIHY
RSPVASAQVKSCLLLAGLLAEGTTQVTEPALSRDHSERMLRAFGANIQVDPETKTVAVVGGSRLVGQRVQVPGDISSAAF
WLVAVSIVPESELLLRDVGLNPTRTGALRVLQEMGADIQIENLREMAGEPLGDLRVRSARLRGCTIAGDLIPTLIDEIPV
LAVAAAFAEGITVIRDAAELRVKESDRLSAMAQELSRMGAQVAEYPDGLEIKGGIPLHGAEVDSHEDHRIAMSLMVAALG
AQGSTLLRGADCARISYPDFIPTLQRLTASPLES
>Mature_433_residues
TLSPAKGLRGQVSIPGDKSISHRALMLGSLAEGETTIQGLLLGEDPRSTAACFRALGADISELNSECVRIRGVGLGQLQE
PADVLDAGNSGTTLRLMLGILAGQAGRFFAVTGDRSLRSRPMGRVVEPLRQMGASIWGRAGGTLAPLAVQGGSLKGIHYR
SPVASAQVKSCLLLAGLLAEGTTQVTEPALSRDHSERMLRAFGANIQVDPETKTVAVVGGSRLVGQRVQVPGDISSAAFW
LVAVSIVPESELLLRDVGLNPTRTGALRVLQEMGADIQIENLREMAGEPLGDLRVRSARLRGCTIAGDLIPTLIDEIPVL
AVAAAFAEGITVIRDAAELRVKESDRLSAMAQELSRMGAQVAEYPDGLEIKGGIPLHGAEVDSHEDHRIAMSLMVAALGA
QGSTLLRGADCARISYPDFIPTLQRLTASPLES

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=445, Percent_Identity=30.561797752809, Blast_Score=145, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6320332, Length=425, Percent_Identity=29.4117647058824, Blast_Score=123, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 45649; Mature: 45518

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSPAKGLRGQVSIPGDKSISHRALMLGSLAEGETTIQGLLLGEDPRSTAACFRALGAD
CCCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCC
ISELNSECVRIRGVGLGQLQEPADVLDAGNSGTTLRLMLGILAGQAGRFFAVTGDRSLRS
HHHHCCHHEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHH
RPMGRVVEPLRQMGASIWGRAGGTLAPLAVQGGSLKGIHYRSPVASAQVKSCLLLAGLLA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHH
EGTTQVTEPALSRDHSERMLRAFGANIQVDPETKTVAVVGGSRLVGQRVQVPGDISSAAF
CCCHHHHHHHHHCHHHHHHHHHHCCCCEECCCCCEEEEECCCHHHCCEECCCCCHHHHHE
WLVAVSIVPESELLLRDVGLNPTRTGALRVLQEMGADIQIENLREMAGEPLGDLRVRSAR
EHHHEECCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHH
LRGCTIAGDLIPTLIDEIPVLAVAAAFAEGITVIRDAAELRVKESDRLSAMAQELSRMGA
HCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QVAEYPDGLEIKGGIPLHGAEVDSHEDHRIAMSLMVAALGAQGSTLLRGADCARISYPDF
HHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
IPTLQRLTASPLES
HHHHHHHHCCCCCC
>Mature Secondary Structure 
TLSPAKGLRGQVSIPGDKSISHRALMLGSLAEGETTIQGLLLGEDPRSTAACFRALGAD
CCCCCCCCCCEEECCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHCCC
ISELNSECVRIRGVGLGQLQEPADVLDAGNSGTTLRLMLGILAGQAGRFFAVTGDRSLRS
HHHHCCHHEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHH
RPMGRVVEPLRQMGASIWGRAGGTLAPLAVQGGSLKGIHYRSPVASAQVKSCLLLAGLLA
CCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHH
EGTTQVTEPALSRDHSERMLRAFGANIQVDPETKTVAVVGGSRLVGQRVQVPGDISSAAF
CCCHHHHHHHHHCHHHHHHHHHHCCCCEECCCCCEEEEECCCHHHCCEECCCCCHHHHHE
WLVAVSIVPESELLLRDVGLNPTRTGALRVLQEMGADIQIENLREMAGEPLGDLRVRSAR
EHHHEECCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHCCCCCHHHHHHHH
LRGCTIAGDLIPTLIDEIPVLAVAAAFAEGITVIRDAAELRVKESDRLSAMAQELSRMGA
HCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QVAEYPDGLEIKGGIPLHGAEVDSHEDHRIAMSLMVAALGAQGSTLLRGADCARISYPDF
HHHHCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHH
IPTLQRLTASPLES
HHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA