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The map label for this gene is carA [H]

Identifier: 86608712

GI number: 86608712

Start: 1279279

End: 1280466

Strand: Reverse

Name: carA [H]

Synonym: CYB_1236

Alternate gene names: 86608712

Gene position: 1280466-1279279 (Counterclockwise)

Preceding gene: 86608713

Following gene: 86608706

Centisome position: 42.03

GC content: 62.21

Gene sequence:

>1188_bases
ATGGCTTCTCCTTCCCTGATCCCTCAGGAAAAAACTTTCCCTTGGCAAACTCGTCAGCCTGCTTTGCTGGTGCTGGCGGA
TGGCACTTCCTTTGCCGGTTGGTCTTTTGGGGCGCCGGGCACGGCGGTGGGCGAGGTGGTGTTTAACACGGGCATGACCG
GCTACCAGGAGGTGATCACCGATCCTAGCTACCGGGGGCAGATGGTTACCTTCACCTGTCCGGAGCTGGGAAACACCGGA
GTCAATGAGCTGGACGAAGAATCGGCTCGGCCCCAAGTCGCGGGGGTGATTGCCCGCAATGTATCGCGCTTGGCCAGCTC
CTGGCGGGCTACTTCCACCCTTCCCCACTATCTGCAACAGCATGGGATCCCGGCCATTGCTGGGGTAGATACGCGGGCTT
TGGCACGGCGGCTGCGCTCCCAGGGGGTGATGAACGGGGCCCTTTCCACGGAGACTTTGGATCCCCAGGTTTTGTTGGAG
CGGGTGCGCCAGGCCCCTTCCATGCAGGGGTTGAGCTTGGTGGCGGAAGTTACTACTCCTCAACCCTACGAGTGGCTGGA
ACCTACCCCCGCCGACTGGGACTATGGGCGCAGCCAAGGGATCCCGATCCCGGAGCCGCCCCTGCGGGTGGTGGCCTTGG
ATTTCGGCGTTAAGCGCAACATTCTGCGCCGCCTCACCCGCTATGGCTGTCGGGTGATGGTGTTGCCGGCCAATGCCAGC
CCGGAGCAGATTTTGAGTTACAACCCCGATGGGATCTTCCTCTCCAATGGGCCAGGGGATCCGGCGGCAGAGACCACGGC
CATCCGCACCACCCAAGCTCTGCTGCAAACCGGGAAGCCCCTATTTGGGATTTGCCTGGGCCATCAGATCCTCAGCTTGG
CCCTAGGGGGATCCACCTACAAGCTCAAGTTTGGCCACCGCGGCCTCAACCATCCCTGTGGGCTGGACAAGCAAGTGGAG
ATCACCAGCCAGAACCACGGGTTTGCGGTGGATGCCGACTCGATCCCTGCCGATGGGGTGGTAATCACCTACCTCAACTT
GAATGACCGTACCGTGGCCGGGATCCGCCACCGTCACCTGCCCCTGTTTTCCGTGCAGTATCACCCGGAAGCCAGCCCCG
GCCCCCACGACGCCGATCACCTCTTCCGCGAGTTCGTGGAGCTGATGCTGCAGCACCGCTCCCGTTAG

Upstream 100 bases:

>100_bases
GACCCGGCTTGTGCAAGTAGAACAGATGCAGAAGACTAGCCAGGCTTGCAACCTTCTTGAAAGAGGGTAGGATGGTCAGG
CCGATGTTTTTGGGTGGAGC

Downstream 100 bases:

>100_bases
CCTCACCCCCGGCTTTTTTCCCTCAGGGCCAGGGCAGCGCGGGCTTCTTCTCGGTCGTCGAAGTGAATCTTCTCGGTGCC
CAGGATCTGGTAGTCCTCAT

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MASPSLIPQEKTFPWQTRQPALLVLADGTSFAGWSFGAPGTAVGEVVFNTGMTGYQEVITDPSYRGQMVTFTCPELGNTG
VNELDEESARPQVAGVIARNVSRLASSWRATSTLPHYLQQHGIPAIAGVDTRALARRLRSQGVMNGALSTETLDPQVLLE
RVRQAPSMQGLSLVAEVTTPQPYEWLEPTPADWDYGRSQGIPIPEPPLRVVALDFGVKRNILRRLTRYGCRVMVLPANAS
PEQILSYNPDGIFLSNGPGDPAAETTAIRTTQALLQTGKPLFGICLGHQILSLALGGSTYKLKFGHRGLNHPCGLDKQVE
ITSQNHGFAVDADSIPADGVVITYLNLNDRTVAGIRHRHLPLFSVQYHPEASPGPHDADHLFREFVELMLQHRSR

Sequences:

>Translated_395_residues
MASPSLIPQEKTFPWQTRQPALLVLADGTSFAGWSFGAPGTAVGEVVFNTGMTGYQEVITDPSYRGQMVTFTCPELGNTG
VNELDEESARPQVAGVIARNVSRLASSWRATSTLPHYLQQHGIPAIAGVDTRALARRLRSQGVMNGALSTETLDPQVLLE
RVRQAPSMQGLSLVAEVTTPQPYEWLEPTPADWDYGRSQGIPIPEPPLRVVALDFGVKRNILRRLTRYGCRVMVLPANAS
PEQILSYNPDGIFLSNGPGDPAAETTAIRTTQALLQTGKPLFGICLGHQILSLALGGSTYKLKFGHRGLNHPCGLDKQVE
ITSQNHGFAVDADSIPADGVVITYLNLNDRTVAGIRHRHLPLFSVQYHPEASPGPHDADHLFREFVELMLQHRSR
>Mature_394_residues
ASPSLIPQEKTFPWQTRQPALLVLADGTSFAGWSFGAPGTAVGEVVFNTGMTGYQEVITDPSYRGQMVTFTCPELGNTGV
NELDEESARPQVAGVIARNVSRLASSWRATSTLPHYLQQHGIPAIAGVDTRALARRLRSQGVMNGALSTETLDPQVLLER
VRQAPSMQGLSLVAEVTTPQPYEWLEPTPADWDYGRSQGIPIPEPPLRVVALDFGVKRNILRRLTRYGCRVMVLPANASP
EQILSYNPDGIFLSNGPGDPAAETTAIRTTQALLQTGKPLFGICLGHQILSLALGGSTYKLKFGHRGLNHPCGLDKQVEI
TSQNHGFAVDADSIPADGVVITYLNLNDRTVAGIRHRHLPLFSVQYHPEASPGPHDADHLFREFVELMLQHRSR

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=382, Percent_Identity=42.4083769633508, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI169790915, Length=390, Percent_Identity=37.9487179487179, Blast_Score=248, Evalue=8e-66,
Organism=Homo sapiens, GI21361331, Length=390, Percent_Identity=37.9487179487179, Blast_Score=247, Evalue=1e-65,
Organism=Escherichia coli, GI1786215, Length=381, Percent_Identity=50.9186351706037, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1788854, Length=182, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193204318, Length=389, Percent_Identity=39.0745501285347, Blast_Score=248, Evalue=3e-66,
Organism=Saccharomyces cerevisiae, GI6322331, Length=397, Percent_Identity=40.3022670025189, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6324878, Length=390, Percent_Identity=38.974358974359, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI45555749, Length=390, Percent_Identity=39.7435897435897, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24642586, Length=390, Percent_Identity=39.7435897435897, Blast_Score=239, Evalue=2e-63,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 43079; Mature: 42948

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPSLIPQEKTFPWQTRQPALLVLADGTSFAGWSFGAPGTAVGEVVFNTGMTGYQEVIT
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHC
DPSYRGQMVTFTCPELGNTGVNELDEESARPQVAGVIARNVSRLASSWRATSTLPHYLQQ
CCCCCCEEEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGIPAIAGVDTRALARRLRSQGVMNGALSTETLDPQVLLERVRQAPSMQGLSLVAEVTTP
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCC
QPYEWLEPTPADWDYGRSQGIPIPEPPLRVVALDFGVKRNILRRLTRYGCRVMVLPANAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCC
PEQILSYNPDGIFLSNGPGDPAAETTAIRTTQALLQTGKPLFGICLGHQILSLALGGSTY
HHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
KLKFGHRGLNHPCGLDKQVEITSQNHGFAVDADSIPADGVVITYLNLNDRTVAGIRHRHL
EEEECCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCEEECHHHCCC
PLFSVQYHPEASPGPHDADHLFREFVELMLQHRSR
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASPSLIPQEKTFPWQTRQPALLVLADGTSFAGWSFGAPGTAVGEVVFNTGMTGYQEVIT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHC
DPSYRGQMVTFTCPELGNTGVNELDEESARPQVAGVIARNVSRLASSWRATSTLPHYLQQ
CCCCCCEEEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HGIPAIAGVDTRALARRLRSQGVMNGALSTETLDPQVLLERVRQAPSMQGLSLVAEVTTP
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEECCC
QPYEWLEPTPADWDYGRSQGIPIPEPPLRVVALDFGVKRNILRRLTRYGCRVMVLPANAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCC
PEQILSYNPDGIFLSNGPGDPAAETTAIRTTQALLQTGKPLFGICLGHQILSLALGGSTY
HHHHHEECCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEE
KLKFGHRGLNHPCGLDKQVEITSQNHGFAVDADSIPADGVVITYLNLNDRTVAGIRHRHL
EEEECCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCEEEEEEECCCCEEECHHHCCC
PLFSVQYHPEASPGPHDADHLFREFVELMLQHRSR
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]