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The map label for this gene is tkt [H]

Identifier: 86608597

GI number: 86608597

Start: 1156391

End: 1158391

Strand: Direct

Name: tkt [H]

Synonym: CYB_1119

Alternate gene names: 86608597

Gene position: 1156391-1158391 (Clockwise)

Preceding gene: 86608596

Following gene: 86608599

Centisome position: 37.96

GC content: 61.37

Gene sequence:

>2001_bases
ATGGTTGTTGCTGCTCCTCCCTCTCTGGAACAACTTGCCATCAATACGATTCGCTTTTTGGCGGTGGATGCTGTTCAGAA
GGCCAACTCCGGCCACCCTGGCCTGCCGATGGGAGCAGCACCCATGGCCTATGTGTTGTGGCAGCAGTTCATGAAGTTCA
ACCCCCGCAACCCCAAGTGGGTGGATCGGGATCGCTTTGTGCTCTCGGCGGGGCATGGCTGCATGCTGCAGTACGCGCTG
CTGCACCTAACCGGCTTCGATGTAAGCCTGGAGGACATTAAGCAGTTCCGCCAGTGGGGCTCCAAAACCCCCGGCCACCC
GGAAAACTTTGAAACTCCGGGGGTGGAGGTGACCACCGGCCCGCTGGGGCAAGGGGTGGGCAATGCGGTAGGGTTGGCCA
TTGCCGAGGCCCATCTGGCCGCCCGCTTCAACAAGCCCGGCCACACCATTGTGGATCACTACACTTACGTGATCTTGGGC
GATGGCTGCAACATGGAAGGGGTGGCTTCTGAAGCAGCTTCTCTGGCCGGCCACCTGCAACTGGGCAAGCTGATCATGCT
TTACGACAGCAACCACATCTCCATCGACGGCAGAACGGAAATCGCCTTTACGGAAGATGTGGGCAAACGCTATGAAGCCT
ACGGCTGGCACGTGCAAAAGGTAGACGACGGCAACCACGACCTGAAGGGGATCGCCGAGGCCATCCAGAGAGCCAAGGAA
GTCACCAACAAGCCGTCCTTGATTATTGTCGAGACCACCATCGGCTACGGATCCCCCAACAAGGCCGGCAGCGAGAGCGT
CCATGGGGCACCCCTGGGGCCGGAAGAGGTGAAGCTCACCAAACAAAACCTGGGCTGGCCGCTGGAGCCGGAGTTTTACA
TTCCCGACGAGGTGCTGGCCCACTTCCGCCAGGCCATCGAAAAAGGGGCCAAGGCCGAGGCCGAGTGGAACGAGCGCTTC
GCCGCCTACGAGAAGGCTTACCCCGAAGAGGCCGCCGAGTTCAAGCGCATCATGGCCGGGGAGCTGCCGGTGGGCTGGAA
AGAAGCGCTGGCCCCCATTGCCGAAACCGGCAGAGAATCCACCCGCAACCTCTCCAAGTTTTGTCTGAATGCCTTGGCCA
AAGCGGTGCCGGAACTGCTGGGGGGATCCGCAGATCTCGCCCACTCCAACATGACTTATCTAAAGGGGATCCCAGAGTTT
CAGGCCGGCTCTTACGAGGGGCGTAACTTCCGCTTTGGGGTGCGGGAACACGGCATGGGAGCCATTGCCAACGGCATGGC
GCTTCATGGAGGTCTCATCCCTTACGACGCCACCTTTTTGATCTTCACAGACTACATGCGGCCTGCCATCCGCCTATCGG
CCCTCTCGCAAGTGCGGGTGCTGCACGTCATGACCCACGACTCCGTCGCCTTGGGAGAAGATGGCCCCACCCACCAGCCG
GTGGAAACTTTGGCCTCCCTGCGGGCCATTCCCAATCTCTATGTGCTGCGCCCGGCAGATGCCCGCGAAACGGTGGGATC
CTACCAGGTGGCCCTAGAAGCCAAGACCACCCCTTCTGTGCTGGTGTTCACCCGGCAGGCGGTCAACCCGGTGGAGGGCA
CCTCTGTTGAAGGCGTAGCCAAAGGGGCCTATGTGGTGGTGGATGCCCCCAACCCAGAGCTGATCTTGATCGCCACCGGC
TCTGAACTGGAGCTGGCAGTGAAAGCTGCAGCCCAACTGAAGCAGGAAGGCCGGGCCGTGCGGGTGGTCTCTATGCCCTG
TATGGAGCTGTTTGAGGCCCAGCCCCAGAGCTACCGCGATTCCGTTCTGCCCCCCAACGTCACCAAGCGCGTCTCCGTCG
AGGCAGGCTGCACCTTCGGCTGGCACAAGTACCTGGGGTTTGAGGGGGTGGCCATTGGCATCGATCGCTTTGGCGCCTCT
GCCCCCGGCCCGGTGTGCATGGAGAAGTTCGGCTTCACGGTGGAAAACGTGGTCAACACTGCCCGCCGGCTGCTGGGCTG
A

Upstream 100 bases:

>100_bases
ACAAAGCCAATTTCCCGGCCCAATTGATCCCTAGCGCCTCGGAAGCAAGACCCAAAACACGGCATACTGGAAAGCAAATG
TCGAGCGATAGGGATCCCAC

Downstream 100 bases:

>100_bases
GGGCACTTTACCCCTTCCTCGGCGCTTTCAAGGGGCTCAGCAGGGATCCCTTCTCTGCTGGGCTTTTTTCCCTGTTGAGC
CTGCTGCCCAGCGGCGTGAC

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MVVAAPPSLEQLAINTIRFLAVDAVQKANSGHPGLPMGAAPMAYVLWQQFMKFNPRNPKWVDRDRFVLSAGHGCMLQYAL
LHLTGFDVSLEDIKQFRQWGSKTPGHPENFETPGVEVTTGPLGQGVGNAVGLAIAEAHLAARFNKPGHTIVDHYTYVILG
DGCNMEGVASEAASLAGHLQLGKLIMLYDSNHISIDGRTEIAFTEDVGKRYEAYGWHVQKVDDGNHDLKGIAEAIQRAKE
VTNKPSLIIVETTIGYGSPNKAGSESVHGAPLGPEEVKLTKQNLGWPLEPEFYIPDEVLAHFRQAIEKGAKAEAEWNERF
AAYEKAYPEEAAEFKRIMAGELPVGWKEALAPIAETGRESTRNLSKFCLNALAKAVPELLGGSADLAHSNMTYLKGIPEF
QAGSYEGRNFRFGVREHGMGAIANGMALHGGLIPYDATFLIFTDYMRPAIRLSALSQVRVLHVMTHDSVALGEDGPTHQP
VETLASLRAIPNLYVLRPADARETVGSYQVALEAKTTPSVLVFTRQAVNPVEGTSVEGVAKGAYVVVDAPNPELILIATG
SELELAVKAAAQLKQEGRAVRVVSMPCMELFEAQPQSYRDSVLPPNVTKRVSVEAGCTFGWHKYLGFEGVAIGIDRFGAS
APGPVCMEKFGFTVENVVNTARRLLG

Sequences:

>Translated_666_residues
MVVAAPPSLEQLAINTIRFLAVDAVQKANSGHPGLPMGAAPMAYVLWQQFMKFNPRNPKWVDRDRFVLSAGHGCMLQYAL
LHLTGFDVSLEDIKQFRQWGSKTPGHPENFETPGVEVTTGPLGQGVGNAVGLAIAEAHLAARFNKPGHTIVDHYTYVILG
DGCNMEGVASEAASLAGHLQLGKLIMLYDSNHISIDGRTEIAFTEDVGKRYEAYGWHVQKVDDGNHDLKGIAEAIQRAKE
VTNKPSLIIVETTIGYGSPNKAGSESVHGAPLGPEEVKLTKQNLGWPLEPEFYIPDEVLAHFRQAIEKGAKAEAEWNERF
AAYEKAYPEEAAEFKRIMAGELPVGWKEALAPIAETGRESTRNLSKFCLNALAKAVPELLGGSADLAHSNMTYLKGIPEF
QAGSYEGRNFRFGVREHGMGAIANGMALHGGLIPYDATFLIFTDYMRPAIRLSALSQVRVLHVMTHDSVALGEDGPTHQP
VETLASLRAIPNLYVLRPADARETVGSYQVALEAKTTPSVLVFTRQAVNPVEGTSVEGVAKGAYVVVDAPNPELILIATG
SELELAVKAAAQLKQEGRAVRVVSMPCMELFEAQPQSYRDSVLPPNVTKRVSVEAGCTFGWHKYLGFEGVAIGIDRFGAS
APGPVCMEKFGFTVENVVNTARRLLG
>Mature_666_residues
MVVAAPPSLEQLAINTIRFLAVDAVQKANSGHPGLPMGAAPMAYVLWQQFMKFNPRNPKWVDRDRFVLSAGHGCMLQYAL
LHLTGFDVSLEDIKQFRQWGSKTPGHPENFETPGVEVTTGPLGQGVGNAVGLAIAEAHLAARFNKPGHTIVDHYTYVILG
DGCNMEGVASEAASLAGHLQLGKLIMLYDSNHISIDGRTEIAFTEDVGKRYEAYGWHVQKVDDGNHDLKGIAEAIQRAKE
VTNKPSLIIVETTIGYGSPNKAGSESVHGAPLGPEEVKLTKQNLGWPLEPEFYIPDEVLAHFRQAIEKGAKAEAEWNERF
AAYEKAYPEEAAEFKRIMAGELPVGWKEALAPIAETGRESTRNLSKFCLNALAKAVPELLGGSADLAHSNMTYLKGIPEF
QAGSYEGRNFRFGVREHGMGAIANGMALHGGLIPYDATFLIFTDYMRPAIRLSALSQVRVLHVMTHDSVALGEDGPTHQP
VETLASLRAIPNLYVLRPADARETVGSYQVALEAKTTPSVLVFTRQAVNPVEGTSVEGVAKGAYVVVDAPNPELILIATG
SELELAVKAAAQLKQEGRAVRVVSMPCMELFEAQPQSYRDSVLPPNVTKRVSVEAGCTFGWHKYLGFEGVAIGIDRFGAS
APGPVCMEKFGFTVENVVNTARRLLG

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI133778974, Length=576, Percent_Identity=28.2986111111111, Blast_Score=176, Evalue=9e-44,
Organism=Homo sapiens, GI205277463, Length=571, Percent_Identity=27.1453590192644, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI4507521, Length=571, Percent_Identity=27.1453590192644, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI225637459, Length=596, Percent_Identity=22.8187919463087, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI225637463, Length=490, Percent_Identity=23.8775510204082, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI225637461, Length=490, Percent_Identity=23.8775510204082, Blast_Score=108, Evalue=2e-23,
Organism=Escherichia coli, GI48994911, Length=669, Percent_Identity=54.2600896860987, Blast_Score=704, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=663, Percent_Identity=55.2036199095023, Blast_Score=702, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17539652, Length=579, Percent_Identity=26.9430051813472, Blast_Score=162, Evalue=6e-40,
Organism=Saccharomyces cerevisiae, GI6325331, Length=665, Percent_Identity=53.2330827067669, Blast_Score=692, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319593, Length=666, Percent_Identity=47.7477477477478, Blast_Score=623, Evalue=1e-179,
Organism=Drosophila melanogaster, GI45551847, Length=582, Percent_Identity=27.6632302405498, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI45550715, Length=582, Percent_Identity=27.6632302405498, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24645119, Length=545, Percent_Identity=27.7064220183486, Blast_Score=159, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24666278, Length=581, Percent_Identity=26.5060240963855, Blast_Score=153, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72175; Mature: 72175

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVAAPPSLEQLAINTIRFLAVDAVQKANSGHPGLPMGAAPMAYVLWQQFMKFNPRNPKW
CEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
VDRDRFVLSAGHGCMLQYALLHLTGFDVSLEDIKQFRQWGSKTPGHPENFETPGVEVTTG
CCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECC
PLGQGVGNAVGLAIAEAHLAARFNKPGHTIVDHYTYVILGDGCNMEGVASEAASLAGHLQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEEECCCCCCHHHHHHHHHHHHHH
LGKLIMLYDSNHISIDGRTEIAFTEDVGKRYEAYGWHVQKVDDGNHDLKGIAEAIQRAKE
HCCEEEEEECCEEEECCCEEEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
VTNKPSLIIVETTIGYGSPNKAGSESVHGAPLGPEEVKLTKQNLGWPLEPEFYIPDEVLA
HCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHEEEHHHCCCCCCCCCCCCHHHHH
HFRQAIEKGAKAEAEWNERFAAYEKAYPEEAAEFKRIMAGELPVGWKEALAPIAETGRES
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHH
TRNLSKFCLNALAKAVPELLGGSADLAHSNMTYLKGIPEFQAGSYEGRNFRFGVREHGMG
HHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHCCCCCCCCCCCCCCCEEECHHHCCCC
AIANGMALHGGLIPYDATFLIFTDYMRPAIRLSALSQVRVLHVMTHDSVALGEDGPTHQP
HHHCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHEEEEEEEECCCEEECCCCCCCCH
VETLASLRAIPNLYVLRPADARETVGSYQVALEAKTTPSVLVFTRQAVNPVEGTSVEGVA
HHHHHHHHCCCCEEEECCCCHHHCCCCEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCC
KGAYVVVDAPNPELILIATGSELELAVKAAAQLKQEGRAVRVVSMPCMELFEAQPQSYRD
CCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCHHHC
SVLPPNVTKRVSVEAGCTFGWHKYLGFEGVAIGIDRFGASAPGPVCMEKFGFTVENVVNT
CCCCCCCCCEEEECCCCCCCHHHHCCCCCEEEEHHHCCCCCCCCHHHHHHCCCHHHHHHH
ARRLLG
HHHHCC
>Mature Secondary Structure
MVVAAPPSLEQLAINTIRFLAVDAVQKANSGHPGLPMGAAPMAYVLWQQFMKFNPRNPKW
CEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
VDRDRFVLSAGHGCMLQYALLHLTGFDVSLEDIKQFRQWGSKTPGHPENFETPGVEVTTG
CCCCCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEECC
PLGQGVGNAVGLAIAEAHLAARFNKPGHTIVDHYTYVILGDGCNMEGVASEAASLAGHLQ
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECEEEEEEECCCCCCHHHHHHHHHHHHHH
LGKLIMLYDSNHISIDGRTEIAFTEDVGKRYEAYGWHVQKVDDGNHDLKGIAEAIQRAKE
HCCEEEEEECCEEEECCCEEEEEEHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHH
VTNKPSLIIVETTIGYGSPNKAGSESVHGAPLGPEEVKLTKQNLGWPLEPEFYIPDEVLA
HCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHEEEHHHCCCCCCCCCCCCHHHHH
HFRQAIEKGAKAEAEWNERFAAYEKAYPEEAAEFKRIMAGELPVGWKEALAPIAETGRES
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHH
TRNLSKFCLNALAKAVPELLGGSADLAHSNMTYLKGIPEFQAGSYEGRNFRFGVREHGMG
HHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCHHHCCCCCCCCCCCCCCCEEECHHHCCCC
AIANGMALHGGLIPYDATFLIFTDYMRPAIRLSALSQVRVLHVMTHDSVALGEDGPTHQP
HHHCCHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHEEEEEEEECCCEEECCCCCCCCH
VETLASLRAIPNLYVLRPADARETVGSYQVALEAKTTPSVLVFTRQAVNPVEGTSVEGVA
HHHHHHHHCCCCEEEECCCCHHHCCCCEEEEEEECCCCCEEEEEHHHCCCCCCCCCCCCC
KGAYVVVDAPNPELILIATGSELELAVKAAAQLKQEGRAVRVVSMPCMELFEAQPQSYRD
CCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCCHHHC
SVLPPNVTKRVSVEAGCTFGWHKYLGFEGVAIGIDRFGASAPGPVCMEKFGFTVENVVNT
CCCCCCCCCEEEECCCCCCCHHHHCCCCCEEEEHHHCCCCCCCCHHHHHHCCCHHHHHHH
ARRLLG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]