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The map label for this gene is pmbA [C]

Identifier: 86608263

GI number: 86608263

Start: 802518

End: 803870

Strand: Reverse

Name: pmbA [C]

Synonym: CYB_0779

Alternate gene names: 86608263

Gene position: 803870-802518 (Counterclockwise)

Preceding gene: 86608265

Following gene: 86608262

Centisome position: 26.39

GC content: 62.08

Gene sequence:

>1353_bases
ATGCCCAGCTCCATCATTTCCCCGGAAAACCTGCTGGATCTTTGTGAACAGGGTGTACACAAGGCATTGGCTGCTGGAGC
CGACCAGGCAGAAGTGTTTGCCAACTCAGGCCGGGAAACGGAAGTCACTTTTGAGAAAAATGACCTCAACCTGGCCCGCA
GCAGCAGCGAGACCCTGTTCGGCATCCGGGTTTTCTGCGACGGCAGGCTGGGCTTTGCCACCTCCAACCGCCCGGAAGAG
CTGGCCGAGACGGCGGCTGAGGCTGTAGCCATGGCCAAGGCTTCGCCGGCGGATCCCCTCAACGGGCTGCCGGAGCCCCA
ACCTTTGCCCCAGGTGCCCTTTGCCCTCGACCCAGGCCTGCTGGAACTGGATGCCGCCGAGCTGACCCAGTTGGGATCCC
AATTGCTGGAGTGGGTGCGATCCAAAGACCCTCGCATCACCATCGACAGCGGCTCCCTCAGCGTTGAGGAAGAGACCCTG
GCTATCGCCTCTTCCACCGGCATCCGCGCCAACTACCACAGTGTCGAGGCGGGGGGATCCCTGTTTGGCATGGCCATCGA
CGGGGACGAGGTGGGCAGCTTTGCCTACGACGGCGACAGTGTGCAGAAGCGGGCCGATCTGGTGCCGGCGCTGGAGCGGG
CTTTTGATCGCTTTGTCCAAAAATGTGTGGGGGCGCTGGGGGCTGGCGAGGGGGAGAGCTTCCGCGGCCCCATTGTCCTG
CCGCCAGATGTGGTGGAGGAGTTTCTAGGGGATCTCCTCTTTGTCTTGGGGGCGGATGCGGTGCGCAAAGGCAAAAGCCC
TCTGGCGCAAAAAATGGGATCCCGGATCGCCAGCCCGTTGCTCACCGTGGTTTCTGAAGGCCTGGGCCTGCCCGGCTACC
CCATTGAGCCCTTCGACCGCGAAGGGATCCCTCGCCAAATCACCCCCTTGGTTCACGAAGGGATCCTCTGCAACTTCATG
TACAACAGCTACGAAGCTCGCGCTGCCGGGATCCCGTCCAACGGCCATGCCACAGGGGGGGCGGGCAGCCTGCCGGGGGT
GGGGCCAGCTTGTTTGAGAGTGGCGCCGGGGACAACCCCCCTGTCCGAGCTCTACGCGATGGATCGAGGAGTTATCGTCA
CCCGCCTCTCCGGCAGCAGCAACCCCATTACCGGTGACTTTTCTGGGGTGGTGAAAGGGGGCTTCTTGGTCAAAGGCGGC
GAGAAACGCCCCATCCTGGAGACCACCATTGCCGGCAATCTCTACGATTGTTTGCGCAATATCTCCGCCATTTCCCAGGA
AGTAACGGTTTTCAACGGCACGGCTGCCTTTCCCGCCCTGCGCATTGAAGATGTATCCATCACTGCGGGCTAA

Upstream 100 bases:

>100_bases
AAGGGGTTGGTGCTGGGACTCCATAGACGGCAGGGGGTCAGGGAAAAGCAGCTCTGAGCCATAGCCGATAATAGGACTGT
CCTCTTGCCATCTCACTTTT

Downstream 100 bases:

>100_bases
GTAAAGCTAGGGGTGTCGAGATCCCGGCAACAGCGATTAACCTCATTCCCAAAAGCTGCGGAGTTGTTCCCATGGGCCAG
GAGATCACCTGCCTCCGTTT

Product: tldD/pmbA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MPSSIISPENLLDLCEQGVHKALAAGADQAEVFANSGRETEVTFEKNDLNLARSSSETLFGIRVFCDGRLGFATSNRPEE
LAETAAEAVAMAKASPADPLNGLPEPQPLPQVPFALDPGLLELDAAELTQLGSQLLEWVRSKDPRITIDSGSLSVEEETL
AIASSTGIRANYHSVEAGGSLFGMAIDGDEVGSFAYDGDSVQKRADLVPALERAFDRFVQKCVGALGAGEGESFRGPIVL
PPDVVEEFLGDLLFVLGADAVRKGKSPLAQKMGSRIASPLLTVVSEGLGLPGYPIEPFDREGIPRQITPLVHEGILCNFM
YNSYEARAAGIPSNGHATGGAGSLPGVGPACLRVAPGTTPLSELYAMDRGVIVTRLSGSSNPITGDFSGVVKGGFLVKGG
EKRPILETTIAGNLYDCLRNISAISQEVTVFNGTAAFPALRIEDVSITAG

Sequences:

>Translated_450_residues
MPSSIISPENLLDLCEQGVHKALAAGADQAEVFANSGRETEVTFEKNDLNLARSSSETLFGIRVFCDGRLGFATSNRPEE
LAETAAEAVAMAKASPADPLNGLPEPQPLPQVPFALDPGLLELDAAELTQLGSQLLEWVRSKDPRITIDSGSLSVEEETL
AIASSTGIRANYHSVEAGGSLFGMAIDGDEVGSFAYDGDSVQKRADLVPALERAFDRFVQKCVGALGAGEGESFRGPIVL
PPDVVEEFLGDLLFVLGADAVRKGKSPLAQKMGSRIASPLLTVVSEGLGLPGYPIEPFDREGIPRQITPLVHEGILCNFM
YNSYEARAAGIPSNGHATGGAGSLPGVGPACLRVAPGTTPLSELYAMDRGVIVTRLSGSSNPITGDFSGVVKGGFLVKGG
EKRPILETTIAGNLYDCLRNISAISQEVTVFNGTAAFPALRIEDVSITAG
>Mature_449_residues
PSSIISPENLLDLCEQGVHKALAAGADQAEVFANSGRETEVTFEKNDLNLARSSSETLFGIRVFCDGRLGFATSNRPEEL
AETAAEAVAMAKASPADPLNGLPEPQPLPQVPFALDPGLLELDAAELTQLGSQLLEWVRSKDPRITIDSGSLSVEEETLA
IASSTGIRANYHSVEAGGSLFGMAIDGDEVGSFAYDGDSVQKRADLVPALERAFDRFVQKCVGALGAGEGESFRGPIVLP
PDVVEEFLGDLLFVLGADAVRKGKSPLAQKMGSRIASPLLTVVSEGLGLPGYPIEPFDREGIPRQITPLVHEGILCNFMY
NSYEARAAGIPSNGHATGGAGSLPGVGPACLRVAPGTTPLSELYAMDRGVIVTRLSGSSNPITGDFSGVVKGGFLVKGGE
KRPILETTIAGNLYDCLRNISAISQEVTVFNGTAAFPALRIEDVSITAG

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790682, Length=450, Percent_Identity=26.4444444444444, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 47141; Mature: 47010

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSSIISPENLLDLCEQGVHKALAAGADQAEVFANSGRETEVTFEKNDLNLARSSSETLF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHHCCCCCCEE
GIRVFCDGRLGFATSNRPEELAETAAEAVAMAKASPADPLNGLPEPQPLPQVPFALDPGL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LELDAAELTQLGSQLLEWVRSKDPRITIDSGSLSVEEETLAIASSTGIRANYHSVEAGGS
EEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECHHHEEEECCCCCCCCCCEECCCCC
LFGMAIDGDEVGSFAYDGDSVQKRADLVPALERAFDRFVQKCVGALGAGEGESFRGPIVL
EEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEC
PPDVVEEFLGDLLFVLGADAVRKGKSPLAQKMGSRIASPLLTVVSEGLGLPGYPIEPFDR
CHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EGIPRQITPLVHEGILCNFMYNSYEARAAGIPSNGHATGGAGSLPGVGPACLRVAPGTTP
CCCCHHHHHHHHCCEEEEHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCH
LSELYAMDRGVIVTRLSGSSNPITGDFSGVVKGGFLVKGGEKRPILETTIAGNLYDCLRN
HHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCCEEEECCCCCCCCHHHHCCHHHHHHHH
ISAISQEVTVFNGTAAFPALRIEDVSITAG
HHHHHHHEEEEECCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
PSSIISPENLLDLCEQGVHKALAAGADQAEVFANSGRETEVTFEKNDLNLARSSSETLF
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEECCCCCHHCCCCCCEE
GIRVFCDGRLGFATSNRPEELAETAAEAVAMAKASPADPLNGLPEPQPLPQVPFALDPGL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LELDAAELTQLGSQLLEWVRSKDPRITIDSGSLSVEEETLAIASSTGIRANYHSVEAGGS
EEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCEECHHHEEEECCCCCCCCCCEECCCCC
LFGMAIDGDEVGSFAYDGDSVQKRADLVPALERAFDRFVQKCVGALGAGEGESFRGPIVL
EEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEC
PPDVVEEFLGDLLFVLGADAVRKGKSPLAQKMGSRIASPLLTVVSEGLGLPGYPIEPFDR
CHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
EGIPRQITPLVHEGILCNFMYNSYEARAAGIPSNGHATGGAGSLPGVGPACLRVAPGTTP
CCCCHHHHHHHHCCEEEEHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHEEECCCCCH
LSELYAMDRGVIVTRLSGSSNPITGDFSGVVKGGFLVKGGEKRPILETTIAGNLYDCLRN
HHHHHHHCCCEEEEEECCCCCCCCCCCHHHHCCCEEEECCCCCCCCHHHHCCHHHHHHHH
ISAISQEVTVFNGTAAFPALRIEDVSITAG
HHHHHHHEEEEECCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]