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The map label for this gene is kdpD [H]

Identifier: 86608197

GI number: 86608197

Start: 727768

End: 728829

Strand: Reverse

Name: kdpD [H]

Synonym: CYB_0712

Alternate gene names: 86608197

Gene position: 728829-727768 (Counterclockwise)

Preceding gene: 86608198

Following gene: 86608196

Centisome position: 23.92

GC content: 61.21

Gene sequence:

>1062_bases
TTGAAACAGCAACCACTCCGCGTACTTGAGTTTTGGCGCCGCCGCTTTCCCCACAGCTTGCGCACCCAGGTGGCATTGGT
CATTGCCAGCCTTTCGTTCGTCCCCAACTTGGTTTTCATCCTGTCGGTGCAGTGGATCTGGCCCGACACGCAGTTCAGCA
CTGAAGGGATCCTCCTGCTGCTGCTGTGGATCCCGTTGCTGGCGGTGCTGTCGGCGGTGGTGGGCTATGCTCTGTCCTCC
ATGATTTTGCGCCCCCTCACCCTGCTGGCCCGCGAGTTGGCTCATTTGGAAACCTTGATTAACCAGCCCGCCCGTTGGAA
TCTGCTGCTCCGCCCCGGGGATCCCCAGGAAGCCCTGATCTTGCGGCAGGCTTTTGCCCAGTTGCTGCGCCAGATCCAGA
TCGATCAAATGCGGCGAGAAGCCTTTACCGCTACCCTCGTTCACGACCTCAAAACCCCCCTCATCGCCTTTGGGCACCTG
CTGAGCGCCTTTAAACAGGATCAACAGCTCGAGCCGGAGCAACGTCGCGCTCTGCTGGATCGCATCCTGCAGGAAAATCA
ACACAATCTCTCTCTGGTGCAGAAAATGGTGGAGGCTCACCGCCTGGAGCGGGGAGAGATCGAGTTGCATCCTCGGCCTT
GTGATCTGGGATCCCTGGCCAGAAAGGTGGCCGAGCGCATGGGATCCCTGGCCCAGGAGCGGGGGATCGATCTGCGAGTC
GAAGGAGAAGGGTGGGGCAACGCCGATGAGGCAGAGCTGGAGCGGGCGCTGGTGAATCTGGTGGACAACGCCTTGCGCTA
CGCACGCCATGCGGTGGTGTTAATCGTCAGCCCCCACCAGATCCAGGTGCAGGATGATGGCCCCGGCTTGCCGGCTCCCC
TAGAAGAGTTGGCCCAACCCTACGTGACCCAGCCCATTCACATTGCCGGCCACCACTACCCAACCGGCTCAGGAGGTCTG
GGGCTATATATCGCCAGGCGCATCCTGCAGGCCCACGGGGGGGACTTGCGGTTGGTCGAGACGGGATCCCAAGGGACTGC
TCTAGCCCTGGTGTTGCGCTAA

Upstream 100 bases:

>100_bases
TAGGAAAGAACTCTTCAGCCTTGACCGTGAGGGGATGTTCATTCTTCCGTACCATTGGTTCATTATTTAAGCAGGTCTTG
TCAAAGCGAGCGCACCGAGT

Downstream 100 bases:

>100_bases
CCCAATAGATTGGTGCTGAACAAGACTGGTGTAGTCATTTTAAGTGACATACTCCCGCACTCATGTTGATGCAAAGCGCT
CCGCGCCGCTAAAGCGAGAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKQQPLRVLEFWRRRFPHSLRTQVALVIASLSFVPNLVFILSVQWIWPDTQFSTEGILLLLLWIPLLAVLSAVVGYALSS
MILRPLTLLARELAHLETLINQPARWNLLLRPGDPQEALILRQAFAQLLRQIQIDQMRREAFTATLVHDLKTPLIAFGHL
LSAFKQDQQLEPEQRRALLDRILQENQHNLSLVQKMVEAHRLERGEIELHPRPCDLGSLARKVAERMGSLAQERGIDLRV
EGEGWGNADEAELERALVNLVDNALRYARHAVVLIVSPHQIQVQDDGPGLPAPLEELAQPYVTQPIHIAGHHYPTGSGGL
GLYIARRILQAHGGDLRLVETGSQGTALALVLR

Sequences:

>Translated_353_residues
MKQQPLRVLEFWRRRFPHSLRTQVALVIASLSFVPNLVFILSVQWIWPDTQFSTEGILLLLLWIPLLAVLSAVVGYALSS
MILRPLTLLARELAHLETLINQPARWNLLLRPGDPQEALILRQAFAQLLRQIQIDQMRREAFTATLVHDLKTPLIAFGHL
LSAFKQDQQLEPEQRRALLDRILQENQHNLSLVQKMVEAHRLERGEIELHPRPCDLGSLARKVAERMGSLAQERGIDLRV
EGEGWGNADEAELERALVNLVDNALRYARHAVVLIVSPHQIQVQDDGPGLPAPLEELAQPYVTQPIHIAGHHYPTGSGGL
GLYIARRILQAHGGDLRLVETGSQGTALALVLR
>Mature_353_residues
MKQQPLRVLEFWRRRFPHSLRTQVALVIASLSFVPNLVFILSVQWIWPDTQFSTEGILLLLLWIPLLAVLSAVVGYALSS
MILRPLTLLARELAHLETLINQPARWNLLLRPGDPQEALILRQAFAQLLRQIQIDQMRREAFTATLVHDLKTPLIAFGHL
LSAFKQDQQLEPEQRRALLDRILQENQHNLSLVQKMVEAHRLERGEIELHPRPCDLGSLARKVAERMGSLAQERGIDLRV
EGEGWGNADEAELERALVNLVDNALRYARHAVVLIVSPHQIQVQDDGPGLPAPLEELAQPYVTQPIHIAGHHYPTGSGGL
GLYIARRILQAHGGDLRLVETGSQGTALALVLR

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788713, Length=281, Percent_Identity=25.6227758007117, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786600, Length=260, Percent_Identity=25.3846153846154, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=27.3913043478261, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39718; Mature: 39718

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQPLRVLEFWRRRFPHSLRTQVALVIASLSFVPNLVFILSVQWIWPDTQFSTEGILLL
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCHHHHHHH
LLWIPLLAVLSAVVGYALSSMILRPLTLLARELAHLETLINQPARWNLLLRPGDPQEALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
LRQAFAQLLRQIQIDQMRREAFTATLVHDLKTPLIAFGHLLSAFKQDQQLEPEQRRALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RILQENQHNLSLVQKMVEAHRLERGEIELHPRPCDLGSLARKVAERMGSLAQERGIDLRV
HHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
EGEGWGNADEAELERALVNLVDNALRYARHAVVLIVSPHQIQVQDDGPGLPAPLEELAQP
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCCCCCCHHHHCCH
YVTQPIHIAGHHYPTGSGGLGLYIARRILQAHGGDLRLVETGSQGTALALVLR
HHCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEC
>Mature Secondary Structure
MKQQPLRVLEFWRRRFPHSLRTQVALVIASLSFVPNLVFILSVQWIWPDTQFSTEGILLL
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCHHHHHHH
LLWIPLLAVLSAVVGYALSSMILRPLTLLARELAHLETLINQPARWNLLLRPGDPQEALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHH
LRQAFAQLLRQIQIDQMRREAFTATLVHDLKTPLIAFGHLLSAFKQDQQLEPEQRRALLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RILQENQHNLSLVQKMVEAHRLERGEIELHPRPCDLGSLARKVAERMGSLAQERGIDLRV
HHHHCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE
EGEGWGNADEAELERALVNLVDNALRYARHAVVLIVSPHQIQVQDDGPGLPAPLEELAQP
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCCCCCCHHHHCCH
YVTQPIHIAGHHYPTGSGGLGLYIARRILQAHGGDLRLVETGSQGTALALVLR
HHCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]