Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 86608033

GI number: 86608033

Start: 556212

End: 556736

Strand: Reverse

Name: lspA [H]

Synonym: CYB_0541

Alternate gene names: 86608033

Gene position: 556736-556212 (Counterclockwise)

Preceding gene: 86608034

Following gene: 86608030

Centisome position: 18.27

GC content: 58.67

Gene sequence:

>525_bases
ATGAAAAACAAAGGCTTTTGGCTGGCCGGGATCCTGGGGGTGATCTTGGATCAGGCGACCAAGCACTGGGCAGTGGAACG
GCTGCTGCCGGGGCCAGAGATTGAGCTGTGGCCAGGGGTGTTTCACCTCACCTACGTGGAGAATACCGGCGCTGCTTGGA
GCCTGTTTGAAGATTCGGCAGAGCTCTTGAAGTGGATCTCGTTGGGGGTAGCGCTGGCATTGGGGCTGCTGGCCATCCGC
GGCGGGATCCTGAGCCGTTGGGAACAGGCGGGCTATGGCTTGGTGTGGGCAGGAGCGGTGGGGAACGGCATCGACCGCTT
CGTCAACGGCTATGTCGTGGACTTTTTCAATTTGATCTGGATTCGCTTTCCGGTATTCAACGTGGCGGATGTGGCCATCA
ACCTCGGGGTGGCCTGCCTGCTGATTGGTCTGCTACAGGACAACTCGAAGAAAACGGGATCGACTTCCGCCTCGCCTCGC
TTGGAGAAAAAGCCCGGTCGCGACAGCACCCACTTTAAGGATTGA

Upstream 100 bases:

>100_bases
AGCTTCTGGGCAATGAGCCGGCAGAAGAGCAGCATGTCAGGATGGGAAAAGTGCTCATCGGGGCGCTCTTGCCGGTGGAC
GTGATTGAGGCCAAGACGAC

Downstream 100 bases:

>100_bases
CCAGCCGATGAACAGCCTTCAGGGATCCCTTGGGATGCTCAGGCCTTTGGCCAGGGGGATCCCCGGTCAGCTGCAAGGAC
TCCGTCCGCCTATTGCAAAC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MKNKGFWLAGILGVILDQATKHWAVERLLPGPEIELWPGVFHLTYVENTGAAWSLFEDSAELLKWISLGVALALGLLAIR
GGILSRWEQAGYGLVWAGAVGNGIDRFVNGYVVDFFNLIWIRFPVFNVADVAINLGVACLLIGLLQDNSKKTGSTSASPR
LEKKPGRDSTHFKD

Sequences:

>Translated_174_residues
MKNKGFWLAGILGVILDQATKHWAVERLLPGPEIELWPGVFHLTYVENTGAAWSLFEDSAELLKWISLGVALALGLLAIR
GGILSRWEQAGYGLVWAGAVGNGIDRFVNGYVVDFFNLIWIRFPVFNVADVAINLGVACLLIGLLQDNSKKTGSTSASPR
LEKKPGRDSTHFKD
>Mature_174_residues
MKNKGFWLAGILGVILDQATKHWAVERLLPGPEIELWPGVFHLTYVENTGAAWSLFEDSAELLKWISLGVALALGLLAIR
GGILSRWEQAGYGLVWAGAVGNGIDRFVNGYVVDFFNLIWIRFPVFNVADVAINLGVACLLIGLLQDNSKKTGSTSASPR
LEKKPGRDSTHFKD

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=153, Percent_Identity=31.3725490196078, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 19065; Mature: 19065

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKGFWLAGILGVILDQATKHWAVERLLPGPEIELWPGVFHLTYVENTGAAWSLFEDSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEECCCCEEHHHHHHH
ELLKWISLGVALALGLLAIRGGILSRWEQAGYGLVWAGAVGNGIDRFVNGYVVDFFNLIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
IRFPVFNVADVAINLGVACLLIGLLQDNSKKTGSTSASPRLEKKPGRDSTHFKD
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNKGFWLAGILGVILDQATKHWAVERLLPGPEIELWPGVFHLTYVENTGAAWSLFEDSA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEECCCCEEHHHHHHH
ELLKWISLGVALALGLLAIRGGILSRWEQAGYGLVWAGAVGNGIDRFVNGYVVDFFNLIW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHH
IRFPVFNVADVAINLGVACLLIGLLQDNSKKTGSTSASPRLEKKPGRDSTHFKD
HHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14621292 [H]