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The map label for this gene is hflX [H]

Identifier: 86607879

GI number: 86607879

Start: 398116

End: 399882

Strand: Reverse

Name: hflX [H]

Synonym: CYB_0382

Alternate gene names: 86607879

Gene position: 399882-398116 (Counterclockwise)

Preceding gene: 86607881

Following gene: 86607878

Centisome position: 13.13

GC content: 63.1

Gene sequence:

>1767_bases
ATGCCCAGGGCTAGCACCTCTCGCCATCAGACCGACCCCCGCTTCAGCTCTGCTATCGCTCCACGACGCTTTCCCGAACA
GGCCAAAGGGTTAAAGCCCCACCAACAAAAGCAACTGCAACGGCTCTATCAACTGCGCCTACCCCCCGACCGCTTGGTGA
CGGTGGAGTTTGCCCAACGGCTGGGATCCCTGACCCAAGATCTGGAAGGTCAGCCCATCAGCGTTTACCTCAACCGGCGC
GGCCAGGTGATCCGCGTAGGGGTGGGATCCCCTTTTGAAACCCAGATTCCCGCTTGGGAATTGCCCCGCCAGGGGGCCGA
GCGCCTATCCGGGATCCGCTGCATCACCACCCAAATGGGGGAGGGGGGCCCCGGTCAAAAAGCGCTGACGGCCATGGCTT
TGCAGCGTTTGGATGCCCTCATCACCCTTTCCGTGTCCAAGTCAGGAGGGCACCGACGCCGGGGAGGAGCGGCTACGGGC
TTTGTTCACCGGGCCTATCTGGCCCATCTGCTGCCGGAGGGAGAGCGCCGTTGGCAGGTTTCTGAGCCTTTGCCTTTGGG
GATCCTGGCGGAACAGGATCTGCAGGAGCTGGTGGCGGAGCTAGAAGATGGCTTTCGGCGCCAAGTGACCGCCCGCCAGG
TGGATCTGGATCAGGATCGGGCCATCCTGGTGGGGCTGCAGGAGTCCGGGCAGAGCTACGAGGATCTCATGGATGGGTTG
GCGGAGCTGAGCCGCCTGGTGGAGAGTGCCGGCGGACAGGTGCTGCAAGCCCTCTGGCAGAGGCGGGAAGGCCCCAATTC
GGCCACGGTAATCGGATCCGGTAAGGTGCAAGAGCTGGCTCTGCTGGTCCAGGATCTGGGCGCTAACTTGGTGGTGTTCG
ACCGGGAACTCACCCCCAGCCAGGTGCGCACCTTGGAAGAGGCGGTGGGGGTGCGGGTGGTGGATCGCAGCGAGGTGATC
CTGGATATTTTTGCCCAGCGGGCCAGAACCCGAGCCGGGAAGCTGCAGGTGGAGCTGGCGCAACTGCAGTATTTGCTGCC
TCGCCTGGCCGGTCGCGGTCGCACCATGTCTCGGTTAGGTGGGGGCATCGGCACCCGTGGCCCTGGGGAAACCCAACTGG
AAATGGAGCGGCGGGCCATCCAGCGGCGCATCAGCAAGCTGCGGCAAGAGGTGGAAGAGCTGCGCCGCCACCGCCAGCGG
CTGCGCCAACGGCGCGAGGCATCCCAAATTCCCGTGGTGGCCCTGGTGGGCTACACCAACGCCGGCAAATCCACCCTCCT
CAATGCCCTCACCCATGCCCAGGTCTACGTGGCCGACCAACTCTTTGCCACCTTGGATCCCACCACGCGGCGGCTGGAGC
TGCCCGACCAGCAGGCGGTGCTGTTGACCGACACAGTGGGATTCCTAACCGAATTACCAGACCAACTGGTGGATGCCTTT
CAAGCCACCCTGGAAGAGGTGACGGAAGCGGATGCCCTGCTGCATGTGGTGGATCTGTCTCACCCCAACTGGGAAGGACA
GATCGAGGCGGTGGAAACCTTGCTGGACAAGCTGCCCTTGGCCACCGGCCCCCGGCAACTGGTGTTCAACAAAATCGACC
GCCTGGATCCCGAATGGGTAGAGGATGTGCGCCTGCTCTACCCCAAAGCCCTGTTTGTTTCCGCCACCACCGGCCAAAAC
CTGGATCAGTTGCACCACACCCTGGCCCAATTTGCTGCAGTTCTAAGCCCCAACCCCTTCGATAGTCAGGAACCCAAGGA
TCCCTAA

Upstream 100 bases:

>100_bases
GGGCCAGTGTTTGCCACCGTTGCTTTTGGATCCCAAGTTCCTGCGGGCAGCTAGCGTGTATGGTAGATGAAAGCTTGTTT
TTGGGTCTTTCCCCGTCCCT

Downstream 100 bases:

>100_bases
AAGCATTCCATAAGGATTTCCAAACCTGCATAGCTCATCTTCATCCGCCGTCAACATAAACATTCAGTTACATTGAGATC
AGGATTGTGACCCGACTTAA

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 587

Protein sequence:

>588_residues
MPRASTSRHQTDPRFSSAIAPRRFPEQAKGLKPHQQKQLQRLYQLRLPPDRLVTVEFAQRLGSLTQDLEGQPISVYLNRR
GQVIRVGVGSPFETQIPAWELPRQGAERLSGIRCITTQMGEGGPGQKALTAMALQRLDALITLSVSKSGGHRRRGGAATG
FVHRAYLAHLLPEGERRWQVSEPLPLGILAEQDLQELVAELEDGFRRQVTARQVDLDQDRAILVGLQESGQSYEDLMDGL
AELSRLVESAGGQVLQALWQRREGPNSATVIGSGKVQELALLVQDLGANLVVFDRELTPSQVRTLEEAVGVRVVDRSEVI
LDIFAQRARTRAGKLQVELAQLQYLLPRLAGRGRTMSRLGGGIGTRGPGETQLEMERRAIQRRISKLRQEVEELRRHRQR
LRQRREASQIPVVALVGYTNAGKSTLLNALTHAQVYVADQLFATLDPTTRRLELPDQQAVLLTDTVGFLTELPDQLVDAF
QATLEEVTEADALLHVVDLSHPNWEGQIEAVETLLDKLPLATGPRQLVFNKIDRLDPEWVEDVRLLYPKALFVSATTGQN
LDQLHHTLAQFAAVLSPNPFDSQEPKDP

Sequences:

>Translated_588_residues
MPRASTSRHQTDPRFSSAIAPRRFPEQAKGLKPHQQKQLQRLYQLRLPPDRLVTVEFAQRLGSLTQDLEGQPISVYLNRR
GQVIRVGVGSPFETQIPAWELPRQGAERLSGIRCITTQMGEGGPGQKALTAMALQRLDALITLSVSKSGGHRRRGGAATG
FVHRAYLAHLLPEGERRWQVSEPLPLGILAEQDLQELVAELEDGFRRQVTARQVDLDQDRAILVGLQESGQSYEDLMDGL
AELSRLVESAGGQVLQALWQRREGPNSATVIGSGKVQELALLVQDLGANLVVFDRELTPSQVRTLEEAVGVRVVDRSEVI
LDIFAQRARTRAGKLQVELAQLQYLLPRLAGRGRTMSRLGGGIGTRGPGETQLEMERRAIQRRISKLRQEVEELRRHRQR
LRQRREASQIPVVALVGYTNAGKSTLLNALTHAQVYVADQLFATLDPTTRRLELPDQQAVLLTDTVGFLTELPDQLVDAF
QATLEEVTEADALLHVVDLSHPNWEGQIEAVETLLDKLPLATGPRQLVFNKIDRLDPEWVEDVRLLYPKALFVSATTGQN
LDQLHHTLAQFAAVLSPNPFDSQEPKDP
>Mature_587_residues
PRASTSRHQTDPRFSSAIAPRRFPEQAKGLKPHQQKQLQRLYQLRLPPDRLVTVEFAQRLGSLTQDLEGQPISVYLNRRG
QVIRVGVGSPFETQIPAWELPRQGAERLSGIRCITTQMGEGGPGQKALTAMALQRLDALITLSVSKSGGHRRRGGAATGF
VHRAYLAHLLPEGERRWQVSEPLPLGILAEQDLQELVAELEDGFRRQVTARQVDLDQDRAILVGLQESGQSYEDLMDGLA
ELSRLVESAGGQVLQALWQRREGPNSATVIGSGKVQELALLVQDLGANLVVFDRELTPSQVRTLEEAVGVRVVDRSEVIL
DIFAQRARTRAGKLQVELAQLQYLLPRLAGRGRTMSRLGGGIGTRGPGETQLEMERRAIQRRISKLRQEVEELRRHRQRL
RQRREASQIPVVALVGYTNAGKSTLLNALTHAQVYVADQLFATLDPTTRRLELPDQQAVLLTDTVGFLTELPDQLVDAFQ
ATLEEVTEADALLHVVDLSHPNWEGQIEAVETLLDKLPLATGPRQLVFNKIDRLDPEWVEDVRLLYPKALFVSATTGQNL
DQLHHTLAQFAAVLSPNPFDSQEPKDP

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=240, Percent_Identity=39.1666666666667, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI310133116, Length=232, Percent_Identity=39.6551724137931, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI310124269, Length=216, Percent_Identity=40.7407407407407, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI310124267, Length=216, Percent_Identity=40.7407407407407, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI310124171, Length=216, Percent_Identity=40.7407407407407, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI310124169, Length=216, Percent_Identity=40.7407407407407, Blast_Score=133, Evalue=5e-31,
Organism=Escherichia coli, GI1790615, Length=337, Percent_Identity=47.1810089020772, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1789574, Length=189, Percent_Identity=29.1005291005291, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561038, Length=217, Percent_Identity=35.4838709677419, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24650079, Length=353, Percent_Identity=35.6940509915014, Blast_Score=139, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 65461; Mature: 65329

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRASTSRHQTDPRFSSAIAPRRFPEQAKGLKPHQQKQLQRLYQLRLPPDRLVTVEFAQR
CCCCCCCCCCCCCHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHEEHHHHHHH
LGSLTQDLEGQPISVYLNRRGQVIRVGVGSPFETQIPAWELPRQGAERLSGIRCITTQMG
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHCCHHHHHHHCCCEEEEEECC
EGGPGQKALTAMALQRLDALITLSVSKSGGHRRRGGAATGFVHRAYLAHLLPEGERRWQV
CCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEC
SEPLPLGILAEQDLQELVAELEDGFRRQVTARQVDLDQDRAILVGLQESGQSYEDLMDGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCHHHHHHHH
AELSRLVESAGGQVLQALWQRREGPNSATVIGSGKVQELALLVQDLGANLVVFDRELTPS
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCHH
QVRTLEEAVGVRVVDRSEVILDIFAQRARTRAGKLQVELAQLQYLLPRLAGRGRTMSRLG
HHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHC
GGIGTRGPGETQLEMERRAIQRRISKLRQEVEELRRHRQRLRQRREASQIPVVALVGYTN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AGKSTLLNALTHAQVYVADQLFATLDPTTRRLELPDQQAVLLTDTVGFLTELPDQLVDAF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEEHHHHHHHHCHHHHHHHH
QATLEEVTEADALLHVVDLSHPNWEGQIEAVETLLDKLPLATGPRQLVFNKIDRLDPEWV
HHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHH
EDVRLLYPKALFVSATTGQNLDQLHHTLAQFAAVLSPNPFDSQEPKDP
HHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PRASTSRHQTDPRFSSAIAPRRFPEQAKGLKPHQQKQLQRLYQLRLPPDRLVTVEFAQR
CCCCCCCCCCCCHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCHHEEHHHHHHH
LGSLTQDLEGQPISVYLNRRGQVIRVGVGSPFETQIPAWELPRQGAERLSGIRCITTQMG
HHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCHHCCHHHHHHHCCCEEEEEECC
EGGPGQKALTAMALQRLDALITLSVSKSGGHRRRGGAATGFVHRAYLAHLLPEGERRWQV
CCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEC
SEPLPLGILAEQDLQELVAELEDGFRRQVTARQVDLDQDRAILVGLQESGQSYEDLMDGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCHHHHHHHH
AELSRLVESAGGQVLQALWQRREGPNSATVIGSGKVQELALLVQDLGANLVVFDRELTPS
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCHH
QVRTLEEAVGVRVVDRSEVILDIFAQRARTRAGKLQVELAQLQYLLPRLAGRGRTMSRLG
HHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHC
GGIGTRGPGETQLEMERRAIQRRISKLRQEVEELRRHRQRLRQRREASQIPVVALVGYTN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AGKSTLLNALTHAQVYVADQLFATLDPTTRRLELPDQQAVLLTDTVGFLTELPDQLVDAF
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEEEEEHHHHHHHHCHHHHHHHH
QATLEEVTEADALLHVVDLSHPNWEGQIEAVETLLDKLPLATGPRQLVFNKIDRLDPEWV
HHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHH
EDVRLLYPKALFVSATTGQNLDQLHHTLAQFAAVLSPNPFDSQEPKDP
HHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]