Click here to switch to the map view.

The map label for this gene is cobU [H]

Identifier: 86607864

GI number: 86607864

Start: 382541

End: 383098

Strand: Direct

Name: cobU [H]

Synonym: CYB_0367

Alternate gene names: 86607864

Gene position: 382541-383098 (Clockwise)

Preceding gene: 86607863

Following gene: 86607865

Centisome position: 12.56

GC content: 61.29

Gene sequence:

>558_bases
ATGTCGATTGTGCTGATCTGTGGCCCTGTGCGCTCTGGCAAAAGCCGGCTGGCAGAGGGTTTGGCTGCGGCTTCGGGCTT
GCCGGTTATCTACCTGGCTACCGGGCCGAAACCCGATCCCAAGACGGATCCAGAATGGGCAGAGCGCGTTCAACAGCACC
GGCAACGGCGGCCTTCCAGTTGGCAAACTTGGGAAACCGGGAGGGACTTGGGGGCAGAACTGCAAAAGTTGCCCCAGCCC
TGTTGTGCGCTGGTGGATTCGCTGGGGGGATGGGTGGCGCAGGGCCTAGACTGTCCCTCTTCAGAATGGGATCCCTTGGT
GCAATCCTTCTTGGCAACCTTGCAAAGCCATAGAGGGGAGATCCTCCTGGTGTCTGAAGAAGTGGGCTGGGGGGTGGTGC
CCGCTTACCCACTGGGGCGGCGGTTTCGGGATCGGATGGGGGAACTGACCCAAAGGCTGGCTCCCCTGGCCGACCAAGTG
TTTTTGGTAACGGCAGGTTTTGCCCTCGATCTCACCCGCCTGGGGATCCCGGTGGCAGGCAAGATGGAACAGAGCTGA

Upstream 100 bases:

>100_bases
GAGATATCGGCTTGGGATCTGTCATGGTCGAGCTTTTGAGCCTGAAGTTCAAGTGCGCTGTTGTTAGGTTAATCTCAAGC
GTCAGTGGATTTCCAGCGTA

Downstream 100 bases:

>100_bases
GATAAGCTGCATTTGCAAGCCAGATAGCTGTGTTGCCGTGCCGATTACCCTCTACCTTCCTGCCAAGGCCATTCAAACTC
TGGATCTCACCCCCGGCCAT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSIVLICGPVRSGKSRLAEGLAAASGLPVIYLATGPKPDPKTDPEWAERVQQHRQRRPSSWQTWETGRDLGAELQKLPQP
CCALVDSLGGWVAQGLDCPSSEWDPLVQSFLATLQSHRGEILLVSEEVGWGVVPAYPLGRRFRDRMGELTQRLAPLADQV
FLVTAGFALDLTRLGIPVAGKMEQS

Sequences:

>Translated_185_residues
MSIVLICGPVRSGKSRLAEGLAAASGLPVIYLATGPKPDPKTDPEWAERVQQHRQRRPSSWQTWETGRDLGAELQKLPQP
CCALVDSLGGWVAQGLDCPSSEWDPLVQSFLATLQSHRGEILLVSEEVGWGVVPAYPLGRRFRDRMGELTQRLAPLADQV
FLVTAGFALDLTRLGIPVAGKMEQS
>Mature_184_residues
SIVLICGPVRSGKSRLAEGLAAASGLPVIYLATGPKPDPKTDPEWAERVQQHRQRRPSSWQTWETGRDLGAELQKLPQPC
CALVDSLGGWVAQGLDCPSSEWDPLVQSFLATLQSHRGEILLVSEEVGWGVVPAYPLGRRFRDRMGELTQRLAPLADQVF
LVTAGFALDLTRLGIPVAGKMEQS

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=184, Percent_Identity=34.2391304347826, Blast_Score=91, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 20183; Mature: 20052

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVLICGPVRSGKSRLAEGLAAASGLPVIYLATGPKPDPKTDPEWAERVQQHRQRRPSS
CEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
WQTWETGRDLGAELQKLPQPCCALVDSLGGWVAQGLDCPSSEWDPLVQSFLATLQSHRGE
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
ILLVSEEVGWGVVPAYPLGRRFRDRMGELTQRLAPLADQVFLVTAGFALDLTRLGIPVAG
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KMEQS
CCCCC
>Mature Secondary Structure 
SIVLICGPVRSGKSRLAEGLAAASGLPVIYLATGPKPDPKTDPEWAERVQQHRQRRPSS
EEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCC
WQTWETGRDLGAELQKLPQPCCALVDSLGGWVAQGLDCPSSEWDPLVQSFLATLQSHRGE
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
ILLVSEEVGWGVVPAYPLGRRFRDRMGELTQRLAPLADQVFLVTAGFALDLTRLGIPVAG
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KMEQS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]