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The map label for this gene is xseA [H]

Identifier: 86607590

GI number: 86607590

Start: 104064

End: 105293

Strand: Direct

Name: xseA [H]

Synonym: CYB_0088

Alternate gene names: 86607590

Gene position: 104064-105293 (Clockwise)

Preceding gene: 86607589

Following gene: 86607591

Centisome position: 3.42

GC content: 61.71

Gene sequence:

>1230_bases
ATGGAGTTTTTGCTCACGGATGAAGCTCCCCTGCTCTCGGTGGGGGGAGTGTCCCGTTATTTGAAATCGCTGCTGGCCGG
GGATCCCTACTTGGCCAGGCTGTGGGTGAGCGGGGAAGTATCCAGTTGCCAGCGCAACCGCAATGGCCACCTGTTCTTGA
CCCTGACCGATCCGGAAACCGGCGACGTTCTCAAGGGGGTGGTCTGGCAGAGCCAAACTTCCCGGCTCAGTTTCTGGCCG
GAAGTGGGGCAACAGGTGCTTGCCCTTGGGCAACTTGGCATCTATAGCGGCGGCAGCCATTATCGCCTCGTCATCTGGCA
ATTGCTGCCTGCCGGGGAAGGGCTGTTGGCGTTGCGATTTCAACAGCTCAAGGCCCGCCTCAGTGCCGAGGGCTTGTTCG
ACAACCAACGACCTCTGCCTGTTCATCCCCAGTGCATTGCCGTCGTCAGTTCCCCCCACGCTGCCGGCTGGGGAGATATT
CGGCGCACCCTCAACCAGCGCTACCCCGGGCTACGGGTGCTGTTCTCCCCAGCTCAAGTGCAAGGGGAGGCGGCCCCGGA
ATCAATTGTGCGGGCCATTCGCCGGGTGGAACAGGATGGGCGGGCGGAAGTGCTTCTTTTGGCGCGGGGCGGTGGAGCCA
GCGAAGATTTGGCCTGTTTTAACGATGAGCGGGTGGTGCGAGCCATTGCCGAATGTCGGATCCCGGTGGTCACCGGGATT
GGCCACCAGCGGGATGAAACCCTGGCTGACTACGCTGCCGACTACGCCGCCCATACCCCAACGGCAGCTGCCGAGCGGAT
CGTGCCGGATCTGGGGGAATTGCAGCGTCAGGGATCCCAGTTGCGCCAGAAGTTGATCGAACGCACTCGCCAAGCTTTGG
AAAGGGCCCAGCAGCGTTTGCAGCAGGCCCAACACCACCTGGCTTACGTGCATCCAGAGCGGCTGTTGCAACAGGCTCAG
GATCGCTTGACCCAACACCAACATCGCCTGCTCCAAGCCGTGCGCCATCGCTTCCAGCAACGCCAACAGCACCAACAGGC
CCTGCAAGATCGCCTCCAAGCGCTCGATCCCGAAGCCATTCTGAAACGGGGCTATGCCTTGGTGCGAGATGAAGAGGGAT
CCCTGATCCGCACCCATCGCCTGCCTCCCCAAACCCGCCTGATGATACAACTGGCCTCGGGAAGCCTATGGGTACGAGTA
GAGGAGAGCCATGAGCCGCCGCAAACGTGA

Upstream 100 bases:

>100_bases
TTGGCTTGCCAACTGCAGGGCTACCGAAAGCCCGCCCTGTACTGCGAAGTAGTCAGGGTCGGGTAGTTTACAAGTGACTT
TAGCCGCCCGCAGCAGTGGG

Downstream 100 bases:

>100_bases
GGAGCCGTGGCGCTATGAAGCAGCCATTGCCGAGGTGGAAACTTTGATTGCCCAGATTGAATCGGGGGAACTGGATCTGG
CAGAAGTGGTGGAGCGCTTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MEFLLTDEAPLLSVGGVSRYLKSLLAGDPYLARLWVSGEVSSCQRNRNGHLFLTLTDPETGDVLKGVVWQSQTSRLSFWP
EVGQQVLALGQLGIYSGGSHYRLVIWQLLPAGEGLLALRFQQLKARLSAEGLFDNQRPLPVHPQCIAVVSSPHAAGWGDI
RRTLNQRYPGLRVLFSPAQVQGEAAPESIVRAIRRVEQDGRAEVLLLARGGGASEDLACFNDERVVRAIAECRIPVVTGI
GHQRDETLADYAADYAAHTPTAAAERIVPDLGELQRQGSQLRQKLIERTRQALERAQQRLQQAQHHLAYVHPERLLQQAQ
DRLTQHQHRLLQAVRHRFQQRQQHQQALQDRLQALDPEAILKRGYALVRDEEGSLIRTHRLPPQTRLMIQLASGSLWVRV
EESHEPPQT

Sequences:

>Translated_409_residues
MEFLLTDEAPLLSVGGVSRYLKSLLAGDPYLARLWVSGEVSSCQRNRNGHLFLTLTDPETGDVLKGVVWQSQTSRLSFWP
EVGQQVLALGQLGIYSGGSHYRLVIWQLLPAGEGLLALRFQQLKARLSAEGLFDNQRPLPVHPQCIAVVSSPHAAGWGDI
RRTLNQRYPGLRVLFSPAQVQGEAAPESIVRAIRRVEQDGRAEVLLLARGGGASEDLACFNDERVVRAIAECRIPVVTGI
GHQRDETLADYAADYAAHTPTAAAERIVPDLGELQRQGSQLRQKLIERTRQALERAQQRLQQAQHHLAYVHPERLLQQAQ
DRLTQHQHRLLQAVRHRFQQRQQHQQALQDRLQALDPEAILKRGYALVRDEEGSLIRTHRLPPQTRLMIQLASGSLWVRV
EESHEPPQT
>Mature_409_residues
MEFLLTDEAPLLSVGGVSRYLKSLLAGDPYLARLWVSGEVSSCQRNRNGHLFLTLTDPETGDVLKGVVWQSQTSRLSFWP
EVGQQVLALGQLGIYSGGSHYRLVIWQLLPAGEGLLALRFQQLKARLSAEGLFDNQRPLPVHPQCIAVVSSPHAAGWGDI
RRTLNQRYPGLRVLFSPAQVQGEAAPESIVRAIRRVEQDGRAEVLLLARGGGASEDLACFNDERVVRAIAECRIPVVTGI
GHQRDETLADYAADYAAHTPTAAAERIVPDLGELQRQGSQLRQKLIERTRQALERAQQRLQQAQHHLAYVHPERLLQQAQ
DRLTQHQHRLLQAVRHRFQQRQQHQQALQDRLQALDPEAILKRGYALVRDEEGSLIRTHRLPPQTRLMIQLASGSLWVRV
EESHEPPQT

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=429, Percent_Identity=34.2657342657343, Blast_Score=227, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45945; Mature: 45945

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLLTDEAPLLSVGGVSRYLKSLLAGDPYLARLWVSGEVSSCQRNRNGHLFLTLTDPET
CCEEECCCCCEEECCHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCCCCEEEEEECCCCC
GDVLKGVVWQSQTSRLSFWPEVGQQVLALGQLGIYSGGSHYRLVIWQLLPAGEGLLALRF
CHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHH
QQLKARLSAEGLFDNQRPLPVHPQCIAVVSSPHAAGWGDIRRTLNQRYPGLRVLFSPAQV
HHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCHHH
QGEAAPESIVRAIRRVEQDGRAEVLLLARGGGASEDLACFNDERVVRAIAECRIPVVTGI
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHCCHHHHHHHHHHCCCCEEECC
GHQRDETLADYAADYAAHTPTAAAERIVPDLGELQRQGSQLRQKLIERTRQALERAQQRL
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQAQHHLAYVHPERLLQQAQDRLTQHQHRLLQAVRHRFQQRQQHQQALQDRLQALDPEAI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LKRGYALVRDEEGSLIRTHRLPPQTRLMIQLASGSLWVRVEESHEPPQT
HHCCCEEEECCCCCEEEECCCCCCCEEEEEEECCEEEEEEECCCCCCCC
>Mature Secondary Structure
MEFLLTDEAPLLSVGGVSRYLKSLLAGDPYLARLWVSGEVSSCQRNRNGHLFLTLTDPET
CCEEECCCCCEEECCHHHHHHHHHHCCCCEEEEEEECCCHHHHHCCCCCEEEEEECCCCC
GDVLKGVVWQSQTSRLSFWPEVGQQVLALGQLGIYSGGSHYRLVIWQLLPAGEGLLALRF
CHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCHHHHHH
QQLKARLSAEGLFDNQRPLPVHPQCIAVVSSPHAAGWGDIRRTLNQRYPGLRVLFSPAQV
HHHHHHHHHCCCCCCCCCCCCCCHHEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCHHH
QGEAAPESIVRAIRRVEQDGRAEVLLLARGGGASEDLACFNDERVVRAIAECRIPVVTGI
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHCCHHHHHHHHHHCCCCEEECC
GHQRDETLADYAADYAAHTPTAAAERIVPDLGELQRQGSQLRQKLIERTRQALERAQQRL
CCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QQAQHHLAYVHPERLLQQAQDRLTQHQHRLLQAVRHRFQQRQQHQQALQDRLQALDPEAI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LKRGYALVRDEEGSLIRTHRLPPQTRLMIQLASGSLWVRVEESHEPPQT
HHCCCEEEECCCCCEEEECCCCCCCEEEEEEECCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA