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The map label for this gene is 86606689

Identifier: 86606689

GI number: 86606689

Start: 2067865

End: 2069631

Strand: Reverse

Name: 86606689

Synonym: CYA_2049

Alternate gene names: NA

Gene position: 2069631-2067865 (Counterclockwise)

Preceding gene: 86606690

Following gene: 86606688

Centisome position: 70.57

GC content: 65.42

Gene sequence:

>1767_bases
GTGGAGTCAGAAAGACCCCCCCTTCGACTGTTTCCCCTGGGCACGGATCCCCGCCGGCAGGGCTGTGCCTACTGGCTGGA
GATGGGATCCCACCGCTTGCTCCTCGATTGCGGTTTGCCTGCTTCCTCCCTCTTCAAGGCCCTGCCAGGGATCCCGGATG
CGGTGATCTGCAGCCATGCTCACTTTGACCACCTGCAGGGGCTGCCCGCCTTTTATCGTCGCTACCCGCAGGTGCCTATC
TATGCCACTCCCCTGACCGCCCACTTGGCGGGCGGCCTGTGGGAGCGGGGCGTTTGGCCGGGCTACGACCGGGAAATTCG
CTTTCCTCCCTTTCGGGCACTGCCCTTTGGCCAGGCACGAGAGATCCTGCCCCATCTGATGCTCACCTTTTTCACAGCCG
GGCACCTGCCGGGAGCAGCGGCAACCCTGCTGCAAAATACCCAGACCACTCCGGCCCAAACCTGCGTCTACACCGGCGAC
TGTTCCCTGGCCTCAACCCGCTTTGCCCCCGGCTTGGATCTCACCGCTTTGCGCCATTGGCAGCCGGACGTGCTGCTCAT
CGAAGCCTCGCTGGGATCCACTCGCCATCCGCCCCGTCGCCATCTGGAAAACCGCCTGGTGGAGCGCCTGCTTGGCGCCT
TGGCTGCAGGCCAGACGGTGCTGTTCCCGCTGCCAGTGCTAGGGTTGGGCCAGGAGTTGATTTTCCTCCTCAAAGCTCAC
CACCGCTTTACCCAAGCTTCCCAGGAGCTGACGGTGTGGGTGGCGCCAGGCCTAGCTGCAGGCTGCAACCTCTACGAACG
CTTGCTCCCCTACCTGCCGGAGCCGGTGCGCAATTTCGCCACCTATCAGCCCTTGTTCTGGGAAGACCGCCTGCAGCCGC
GGGTGCAGCCCCTCACGGAGGCGGATCCCCTGCCCCAGGGCCTGTTGCTGTGCGATGCCGATGCCGGGCCTGAAGCCTGG
GATCCCATCTGGTCGCGCTTGCTGGCCCAGCCGCAGCGCTCCTGTCTGCTGGTGCGGCTGCCGGAAGTGGAGCTGGCCAC
CCCCTTTGACCAATGGCCAGCGCCGCTGCGCTCCCGCATCGGAGTGGAGTGGCTGGCCTGGCACAGCCACAACGACGTTG
GGCATCTGACCCAGATCGTCCACACCTTTCGCCCCCAACATGTGGTCTTGGTGCACGCCAGCCCCCAGCAGGCGCAGGAT
CTGGCGGATCTGCCGGAGCTGTGCAACCGTTACCATGTCCACTGCCCCCAACCCGGCCATTGGTTGGAGCTGCCTGACGG
CCGCCTGCAAACCCAAGTCAAGCCGTCAGAATTTCCCAGGGATCCCGCCTTGCGCTACGAGGGGGAGGTGGAAGAGATCT
GGCAGGAACAGGGCTCGCCCCGCGCCTTGGCCGGCGTACAGGTACGGCTGCCCCCTCAGATTGCCCAGGATCCCCGCTGG
GCCGCCTGGGCTGAGACTGGCTTGGTGGAGGCCCGCTGGCAGGGATCCGAACTGGTGTTGCGCGGCCTTTCGCCGCGGGA
GCTGATCCGCCCGGCAGGGGCCGCCCCCGCACCAGCAGGAATCGTGCCGCGTCCAAAACAGCCTTCTGCCTCCACCGATA
ACGGTGGCAGAAAGTGCCAGAACTGCCGCTTTGCCCGCCAGATCTTAACCTCACAAGCCCAAGCCTTTCGCTGCGACCAA
GAGCGCTCCCCCCTCTACCGCCTCCGGGTGGATCCGCAAGGAAGCTGTCCCTACCATCAGCCGCTGGAAATCCGCTCTTC
CGGTTAG

Upstream 100 bases:

>100_bases
TTCCGGGAGGTGTACGGAGGGGGAGGGGCGATCCCTGGCCGAGCCGCCCTTGTGGTTTGCAGGATTGAGCGTGGTCTTCT
AGCTTAAAAACAACACATCT

Downstream 100 bases:

>100_bases
TCAGCCCCCGAAGCCCCAGCAGCCCAAAGGCTAGAATGGGGCCAGTCGCGGTACCCACCATGCTTGAGCAACAACCCTGG
GCAGATCGTCGCCAGGGGCT

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MESERPPLRLFPLGTDPRRQGCAYWLEMGSHRLLLDCGLPASSLFKALPGIPDAVICSHAHFDHLQGLPAFYRRYPQVPI
YATPLTAHLAGGLWERGVWPGYDREIRFPPFRALPFGQAREILPHLMLTFFTAGHLPGAAATLLQNTQTTPAQTCVYTGD
CSLASTRFAPGLDLTALRHWQPDVLLIEASLGSTRHPPRRHLENRLVERLLGALAAGQTVLFPLPVLGLGQELIFLLKAH
HRFTQASQELTVWVAPGLAAGCNLYERLLPYLPEPVRNFATYQPLFWEDRLQPRVQPLTEADPLPQGLLLCDADAGPEAW
DPIWSRLLAQPQRSCLLVRLPEVELATPFDQWPAPLRSRIGVEWLAWHSHNDVGHLTQIVHTFRPQHVVLVHASPQQAQD
LADLPELCNRYHVHCPQPGHWLELPDGRLQTQVKPSEFPRDPALRYEGEVEEIWQEQGSPRALAGVQVRLPPQIAQDPRW
AAWAETGLVEARWQGSELVLRGLSPRELIRPAGAAPAPAGIVPRPKQPSASTDNGGRKCQNCRFARQILTSQAQAFRCDQ
ERSPLYRLRVDPQGSCPYHQPLEIRSSG

Sequences:

>Translated_588_residues
MESERPPLRLFPLGTDPRRQGCAYWLEMGSHRLLLDCGLPASSLFKALPGIPDAVICSHAHFDHLQGLPAFYRRYPQVPI
YATPLTAHLAGGLWERGVWPGYDREIRFPPFRALPFGQAREILPHLMLTFFTAGHLPGAAATLLQNTQTTPAQTCVYTGD
CSLASTRFAPGLDLTALRHWQPDVLLIEASLGSTRHPPRRHLENRLVERLLGALAAGQTVLFPLPVLGLGQELIFLLKAH
HRFTQASQELTVWVAPGLAAGCNLYERLLPYLPEPVRNFATYQPLFWEDRLQPRVQPLTEADPLPQGLLLCDADAGPEAW
DPIWSRLLAQPQRSCLLVRLPEVELATPFDQWPAPLRSRIGVEWLAWHSHNDVGHLTQIVHTFRPQHVVLVHASPQQAQD
LADLPELCNRYHVHCPQPGHWLELPDGRLQTQVKPSEFPRDPALRYEGEVEEIWQEQGSPRALAGVQVRLPPQIAQDPRW
AAWAETGLVEARWQGSELVLRGLSPRELIRPAGAAPAPAGIVPRPKQPSASTDNGGRKCQNCRFARQILTSQAQAFRCDQ
ERSPLYRLRVDPQGSCPYHQPLEIRSSG
>Mature_588_residues
MESERPPLRLFPLGTDPRRQGCAYWLEMGSHRLLLDCGLPASSLFKALPGIPDAVICSHAHFDHLQGLPAFYRRYPQVPI
YATPLTAHLAGGLWERGVWPGYDREIRFPPFRALPFGQAREILPHLMLTFFTAGHLPGAAATLLQNTQTTPAQTCVYTGD
CSLASTRFAPGLDLTALRHWQPDVLLIEASLGSTRHPPRRHLENRLVERLLGALAAGQTVLFPLPVLGLGQELIFLLKAH
HRFTQASQELTVWVAPGLAAGCNLYERLLPYLPEPVRNFATYQPLFWEDRLQPRVQPLTEADPLPQGLLLCDADAGPEAW
DPIWSRLLAQPQRSCLLVRLPEVELATPFDQWPAPLRSRIGVEWLAWHSHNDVGHLTQIVHTFRPQHVVLVHASPQQAQD
LADLPELCNRYHVHCPQPGHWLELPDGRLQTQVKPSEFPRDPALRYEGEVEEIWQEQGSPRALAGVQVRLPPQIAQDPRW
AAWAETGLVEARWQGSELVLRGLSPRELIRPAGAAPAPAGIVPRPKQPSASTDNGGRKCQNCRFARQILTSQAQAFRCDQ
ERSPLYRLRVDPQGSCPYHQPLEIRSSG

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0047, MJ0162 and MJ1236 [H]

Homologues:

Organism=Homo sapiens, GI7706427, Length=431, Percent_Identity=21.1136890951276, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32564696, Length=462, Percent_Identity=23.3766233766234, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566029, Length=439, Percent_Identity=22.5512528473804, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648013, Length=438, Percent_Identity=23.2876712328767, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358523, Length=440, Percent_Identity=22.2727272727273, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 65848; Mature: 65848

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESERPPLRLFPLGTDPRRQGCAYWLEMGSHRLLLDCGLPASSLFKALPGIPDAVICSHA
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCHHHHHCCC
HFDHLQGLPAFYRRYPQVPIYATPLTAHLAGGLWERGVWPGYDREIRFPPFRALPFGQAR
CHHHHCCCHHHHHHCCCCCEEECCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCHHH
EILPHLMLTFFTAGHLPGAAATLLQNTQTTPAQTCVYTGDCSLASTRFAPGLDLTALRHW
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCC
QPDVLLIEASLGSTRHPPRRHLENRLVERLLGALAAGQTVLFPLPVLGLGQELIFLLKAH
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHCCHHHHHHHHHH
HRFTQASQELTVWVAPGLAAGCNLYERLLPYLPEPVRNFATYQPLFWEDRLQPRVQPLTE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCCCCCC
ADPLPQGLLLCDADAGPEAWDPIWSRLLAQPQRSCLLVRLPEVELATPFDQWPAPLRSRI
CCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCHHHHHHC
GVEWLAWHSHNDVGHLTQIVHTFRPQHVVLVHASPQQAQDLADLPELCNRYHVHCPQPGH
CCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCEECCCCCCC
WLELPDGRLQTQVKPSEFPRDPALRYEGEVEEIWQEQGSPRALAGVQVRLPPQIAQDPRW
EEECCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHCCCCCEEECEEEECCHHHCCCCCC
AAWAETGLVEARWQGSELVLRGLSPRELIRPAGAAPAPAGIVPRPKQPSASTDNGGRKCQ
HHHHHCCCEEEECCCCHHEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
NCRFARQILTSQAQAFRCDQERSPLYRLRVDPQGSCPYHQPLEIRSSG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MESERPPLRLFPLGTDPRRQGCAYWLEMGSHRLLLDCGLPASSLFKALPGIPDAVICSHA
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCHHHHHCCC
HFDHLQGLPAFYRRYPQVPIYATPLTAHLAGGLWERGVWPGYDREIRFPPFRALPFGQAR
CHHHHCCCHHHHHHCCCCCEEECCHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCHHH
EILPHLMLTFFTAGHLPGAAATLLQNTQTTPAQTCVYTGDCSLASTRFAPGLDLTALRHW
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCC
QPDVLLIEASLGSTRHPPRRHLENRLVERLLGALAAGQTVLFPLPVLGLGQELIFLLKAH
CCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHCCHHHHHHHHHH
HRFTQASQELTVWVAPGLAAGCNLYERLLPYLPEPVRNFATYQPLFWEDRLQPRVQPLTE
HHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHCCCCCCCCCC
ADPLPQGLLLCDADAGPEAWDPIWSRLLAQPQRSCLLVRLPEVELATPFDQWPAPLRSRI
CCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHCCHHHHHHC
GVEWLAWHSHNDVGHLTQIVHTFRPQHVVLVHASPQQAQDLADLPELCNRYHVHCPQPGH
CCEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCEECCCCCCC
WLELPDGRLQTQVKPSEFPRDPALRYEGEVEEIWQEQGSPRALAGVQVRLPPQIAQDPRW
EEECCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHCCCCCEEECEEEECCHHHCCCCCC
AAWAETGLVEARWQGSELVLRGLSPRELIRPAGAAPAPAGIVPRPKQPSASTDNGGRKCQ
HHHHHCCCEEEECCCCHHEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
NCRFARQILTSQAQAFRCDQERSPLYRLRVDPQGSCPYHQPLEIRSSG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]