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The map label for this gene is tcrA [H]

Identifier: 86606667

GI number: 86606667

Start: 2043231

End: 2043920

Strand: Reverse

Name: tcrA [H]

Synonym: CYA_2027

Alternate gene names: 86606667

Gene position: 2043920-2043231 (Counterclockwise)

Preceding gene: 86606669

Following gene: 86606666

Centisome position: 69.69

GC content: 63.91

Gene sequence:

>690_bases
ATGCGAATTTTGTTGGTGGAAGACGACCTGGAGCAGTTGGAGCCTTTGCAGGCTGCTCTGGCCAAGTGCGGCCATGTGGT
GGACTGCGCCAGCGAAGGGGAGACGGCTGCCTGGCTGATGGAGGAGAAAGCCTATGATCTCCTCATCTTGGATTGGATGC
TGCCGGGGATCAGCGGGATCCAACTCTGTCAGCAGTACCGCCGCTCGGGGGGATGCGCACCGGTGCTGATGTTAACCGCC
AAGGATGCCACGTCGGACATCGTACAGGGGTTGGATGCGGGGGCAGACGACTACCTGGTCAAGCCGGTGGATCTGATAGA
GCTGCTGGCGCGGGTGCGGGCGTTGGGGCGCCGTTCCCCCCAATGGCAAGGCGACAGCCTCAGCCTCGGATCCCTGCAGT
TGCACCTGGCCAGCCTCACCCTGGAGCGGCAGGGGCGGCAAGTGCAGCTTTCGGGCAAAGAGTTTCAGTTGATGGAGTAC
CTGATGCGCCACCCCCACCAGGTGCTCAGTGGGGGCCAGATCGAGCAGGCGGTGTGGGAGTGGGGCTGTGAGCCGGAAAG
CAATGCCGTGGCGGCGCTGGTGCGGCGGTTGCGGTTACGGTTAAAGGAGGTGGAGGCCCAGGATTGGCTGGAGTCGGTGT
ACGGCCAGGGGTACCGGCTGCGCATCCCCTCCCCGGAAGCAGACCCATAG

Upstream 100 bases:

>100_bases
GAAGCTTGAACGGGTTGGCCATGGTTTGAGGGATCCGGGAGATGGCTTTTCTCCGCCATCCTAGCCTGGCAGAGTGGGAT
CGGTGGGTAGCAAGCGGGAC

Downstream 100 bases:

>100_bases
AAGCAGTTCCCTAGAGGTGGCATGGAGGCCAAAAGAGCCGGGCCAAAGCATTCTCTCCCGCGGCTGGGCTGGGACTGGGT
TTCTCTGAGGCCAACTTTTC

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MRILLVEDDLEQLEPLQAALAKCGHVVDCASEGETAAWLMEEKAYDLLILDWMLPGISGIQLCQQYRRSGGCAPVLMLTA
KDATSDIVQGLDAGADDYLVKPVDLIELLARVRALGRRSPQWQGDSLSLGSLQLHLASLTLERQGRQVQLSGKEFQLMEY
LMRHPHQVLSGGQIEQAVWEWGCEPESNAVAALVRRLRLRLKEVEAQDWLESVYGQGYRLRIPSPEADP

Sequences:

>Translated_229_residues
MRILLVEDDLEQLEPLQAALAKCGHVVDCASEGETAAWLMEEKAYDLLILDWMLPGISGIQLCQQYRRSGGCAPVLMLTA
KDATSDIVQGLDAGADDYLVKPVDLIELLARVRALGRRSPQWQGDSLSLGSLQLHLASLTLERQGRQVQLSGKEFQLMEY
LMRHPHQVLSGGQIEQAVWEWGCEPESNAVAALVRRLRLRLKEVEAQDWLESVYGQGYRLRIPSPEADP
>Mature_229_residues
MRILLVEDDLEQLEPLQAALAKCGHVVDCASEGETAAWLMEEKAYDLLILDWMLPGISGIQLCQQYRRSGGCAPVLMLTA
KDATSDIVQGLDAGADDYLVKPVDLIELLARVRALGRRSPQWQGDSLSLGSLQLHLASLTLERQGRQVQLSGKEFQLMEY
LMRHPHQVLSGGQIEQAVWEWGCEPESNAVAALVRRLRLRLKEVEAQDWLESVYGQGYRLRIPSPEADP

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=37.5, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=39.5454545454545, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=35, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=35.1351351351351, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=32.1100917431193, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=33.6363636363636, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=29.7777777777778, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=31.8385650224215, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=28.7610619469027, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=31.3636363636364, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=35.6828193832599, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=27.1929824561404, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=32.1266968325792, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=181, Percent_Identity=27.6243093922652, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=26.6375545851528, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=34.2592592592593, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788521, Length=97, Percent_Identity=37.1134020618557, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25560; Mature: 25560

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDDLEQLEPLQAALAKCGHVVDCASEGETAAWLMEEKAYDLLILDWMLPGISGI
CEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCEEEHHHHHCCCHHH
QLCQQYRRSGGCAPVLMLTAKDATSDIVQGLDAGADDYLVKPVDLIELLARVRALGRRSP
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHCCCC
QWQGDSLSLGSLQLHLASLTLERQGRQVQLSGKEFQLMEYLMRHPHQVLSGGQIEQAVWE
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCHHHHCCCHHHHHHHH
WGCEPESNAVAALVRRLRLRLKEVEAQDWLESVYGQGYRLRIPSPEADP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure
MRILLVEDDLEQLEPLQAALAKCGHVVDCASEGETAAWLMEEKAYDLLILDWMLPGISGI
CEEEEECCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHCCCCEEEHHHHHCCCHHH
QLCQQYRRSGGCAPVLMLTAKDATSDIVQGLDAGADDYLVKPVDLIELLARVRALGRRSP
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHHHHCCCC
QWQGDSLSLGSLQLHLASLTLERQGRQVQLSGKEFQLMEYLMRHPHQVLSGGQIEQAVWE
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCHHHHCCCHHHHHHHH
WGCEPESNAVAALVRRLRLRLKEVEAQDWLESVYGQGYRLRIPSPEADP
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]