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The map label for this gene is yycF [H]

Identifier: 86606539

GI number: 86606539

Start: 1899291

End: 1900046

Strand: Reverse

Name: yycF [H]

Synonym: CYA_1892

Alternate gene names: 86606539

Gene position: 1900046-1899291 (Counterclockwise)

Preceding gene: 86606540

Following gene: 86606538

Centisome position: 64.79

GC content: 61.11

Gene sequence:

>756_bases
ATGGCTCGCATACTCATCATTGAGGACGACCCTTCAATTCTGGATATTCTGCGTATCAATCTGGAGTTGGCGGGCTATGA
GGTCGTGAAGGCCACCGATGGGGTACGCGGACAAGCACTGGCTCTGCAGGTTCTTCCGGATCTCATCATTCTCGACCTGA
TGCTGCCCCAGGTGGACGGCCTGACGGTTTGCCAGCGCTTGCGGCGGGAGGAGCGCACCAGCGAGATCCCGATCCTGATG
CTCACCGCCCTCGGCCAAACCCAAGACAAGATTGAAGGCTTCAACGCTGGCGCCGACGACTACCTGACCAAACCCTTTGA
GGTGCAGGAGCTGCTGGTGCGGGTGCGGGCCCTGCTGCGACGTGCCGATCGCATTCCCCAGACGGCCAAACACGGCGAGA
TCCTCACCTATGGCCCCCTCACCCTGGTGCCAGAGCGCTTCGAGGCGGTGTGGTTTGGCAAAACCATTAAGCTCACCCAC
CTGGAGTTTGACCTGCTCCACTGCCTGATGCAGCGGCACGGCCAGACAGTCTCCCCCAGCGAAATCCTGCAGGAAGTGTG
GGGCTACGAGCCCGACGACGACATCGAGACCATTCGCGTCCACATCCGCCATCTGCGCACCAAGCTGGAGCCGGATCCGC
GCCACCCCCAGTACATCAAAACTGTCTACGGGGCGGGCTACTGTCTGGAGCTGCCCAACATTGCCGATCCCCAGCCGCTG
CAGCCGGAACTGGCAAAAGACTCCTCTTCCCCGTAA

Upstream 100 bases:

>100_bases
AATGAGGCTAGAATTAAGTAAACTTTGAGTCGTAAAGCTTTGGACTCTTGTTAGCTGATTTAACAAAACGTTTTATCCGC
AGTTTGGGCTGCAACCGGCT

Downstream 100 bases:

>100_bases
AAACCACCTGCCGTAGGAGAGCATGACTCTAGTCAATGATATGCTGGACTATACTGAAAATAATGTACAGTATGTTCAGT
ATGGCTGCTTGGTATGGCTA

Product: DNA-binding response regulator RpaA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MARILIIEDDPSILDILRINLELAGYEVVKATDGVRGQALALQVLPDLIILDLMLPQVDGLTVCQRLRREERTSEIPILM
LTALGQTQDKIEGFNAGADDYLTKPFEVQELLVRVRALLRRADRIPQTAKHGEILTYGPLTLVPERFEAVWFGKTIKLTH
LEFDLLHCLMQRHGQTVSPSEILQEVWGYEPDDDIETIRVHIRHLRTKLEPDPRHPQYIKTVYGAGYCLELPNIADPQPL
QPELAKDSSSP

Sequences:

>Translated_251_residues
MARILIIEDDPSILDILRINLELAGYEVVKATDGVRGQALALQVLPDLIILDLMLPQVDGLTVCQRLRREERTSEIPILM
LTALGQTQDKIEGFNAGADDYLTKPFEVQELLVRVRALLRRADRIPQTAKHGEILTYGPLTLVPERFEAVWFGKTIKLTH
LEFDLLHCLMQRHGQTVSPSEILQEVWGYEPDDDIETIRVHIRHLRTKLEPDPRHPQYIKTVYGAGYCLELPNIADPQPL
QPELAKDSSSP
>Mature_250_residues
ARILIIEDDPSILDILRINLELAGYEVVKATDGVRGQALALQVLPDLIILDLMLPQVDGLTVCQRLRREERTSEIPILML
TALGQTQDKIEGFNAGADDYLTKPFEVQELLVRVRALLRRADRIPQTAKHGEILTYGPLTLVPERFEAVWFGKTIKLTHL
EFDLLHCLMQRHGQTVSPSEILQEVWGYEPDDDIETIRVHIRHLRTKLEPDPRHPQYIKTVYGAGYCLELPNIADPQPLQ
PELAKDSSSP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=36.4444444444444, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=37.6623376623377, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=39.3013100436681, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=35.3711790393013, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=37.4449339207048, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=37.3390557939914, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=37.6068376068376, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787375, Length=233, Percent_Identity=33.4763948497854, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.8017621145374, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=36.7965367965368, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=31.858407079646, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=33.1877729257642, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=28.0334728033473, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788550, Length=150, Percent_Identity=28.6666666666667, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28494; Mature: 28363

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILIIEDDPSILDILRINLELAGYEVVKATDGVRGQALALQVLPDLIILDLMLPQVDG
CEEEEEECCCCCEEHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
LTVCQRLRREERTSEIPILMLTALGQTQDKIEGFNAGADDYLTKPFEVQELLVRVRALLR
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
RADRIPQTAKHGEILTYGPLTLVPERFEAVWFGKTIKLTHLEFDLLHCLMQRHGQTVSPS
HHHCCCCCCCCCCEEEECCHHCCHHHHHHEEECCEEEEEHHHHHHHHHHHHHCCCCCCHH
EILQEVWGYEPDDDIETIRVHIRHLRTKLEPDPRHPQYIKTVYGAGYCLELPNIADPQPL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCC
QPELAKDSSSP
CCHHCCCCCCC
>Mature Secondary Structure 
ARILIIEDDPSILDILRINLELAGYEVVKATDGVRGQALALQVLPDLIILDLMLPQVDG
EEEEEECCCCCEEHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCH
LTVCQRLRREERTSEIPILMLTALGQTQDKIEGFNAGADDYLTKPFEVQELLVRVRALLR
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHH
RADRIPQTAKHGEILTYGPLTLVPERFEAVWFGKTIKLTHLEFDLLHCLMQRHGQTVSPS
HHHCCCCCCCCCCEEEECCHHCCHHHHHHEEECCEEEEEHHHHHHHHHHHHHCCCCCCHH
EILQEVWGYEPDDDIETIRVHIRHLRTKLEPDPRHPQYIKTVYGAGYCLELPNIADPQPL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCC
QPELAKDSSSP
CCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]