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The map label for this gene is tig

Identifier: 86605921

GI number: 86605921

Start: 1249105

End: 1250778

Strand: Reverse

Name: tig

Synonym: CYA_1238

Alternate gene names: 86605921

Gene position: 1250778-1249105 (Counterclockwise)

Preceding gene: 86605922

Following gene: 86605914

Centisome position: 42.65

GC content: 60.63

Gene sequence:

>1674_bases
ATGCAGGTCACACAAGAAAAACGTCCTGGCAGCCGGGTTGGCCTCAAGATCGTGGTAGAAGCCGACCAGGTTAAGCGCTC
CTACGAAAAAACCTTGCGCCAACTGGAGCGGAATATCCAGATCCCCGGATTTCGCAAGGGCAAAGCTCCCCGCAACCTGG
TGATACGCCAGGTGGGCCGCGAGCGCGTCATGGCCAGTGCCGTCGATGACCTGATCAACGAGGCCATCCAACAGGCGCTC
AAGGACACCCAACTGCATCCCATCAGCCGCTTCGAGCTGGACGACAAGGTGGAGCAGCTTCTGGATCGCTTCAACCCGGA
GGCCGACTTCAGCTTCTCGGGGTATGTGGAGGTGTACCCCGAAGCCCGTGTCGGCCAATACAAGGGCCTGACCGTCACGG
CCACCCGCGTCACCGTCAAGCCCGAACAGATCGACCAGCTCATCGACCGGTGGCGGGATCAGCGGGCCACCCTCTTGCCG
GTGGAGGATCGGCCCGCCCAGTTGGGGGATGTGGTGGTGATCGATTTTCAAGCCCGCGATGCCGAGGGCAATCCTCTGGA
GGAAATCGCCGCCCAGGACTTTCAGTTGGAGCTCAAAGAGGAGAACTTCATCCCTGGTTTTGTGGCGGGCGTGGTCGGCA
TGCAGCTCGACCAAACCAAGGAGATCACAGCTACTTTCCCCGACGATTACTTCAGAAAAGAGTTGGCCGGGAAAACGGTT
ACGTTCACCGTCTGCCTCAAAGAGATCAAGACCAAAGAGCTGCCGGAGCTGGATGACGCCTTTGTGCAGGAGATCAGCGA
GTTTCAGACGGTGGCCGAACTGCGGGAACACCTGCAAAAGCGCCTCGAGCAAGATGCCCTGCGGCAATCTGAGGAGAACC
TGGAGACGGCCATCCTCAATGCCATCTTGGAAACCACCGAGGTGGATCTGCCGGAGACCCTAGTCGAGCAAGAAACGACA
CAACTGCTGGCCCGAAGCCTTCAGTCGCTGCAGCAGCAGCAAGGGGTCACGCCGGGAGAGATCCGCAAGTTCTTGTCCCA
ACTGCCGCCGGAAACTCTCAACCAGTTGATGGAGCGCCACCGGCCCGAGGCCATCAACCGGCTGCGGCGCACCTTGGCTC
TGAGCGCTATCGTCCGGCAGGAGCAGATTGCCGTAGGCCCCAACGAATTGGAAGTCGAGGTGGAAGAGGTGATGGCGGCC
TATGCGCAGCAAGGGCAGAAGCTGGATCGGGAGCGAGTCCGCCAAGCAGTCCACGAAGATCTGCTCGCCAACAAGGTGAT
GGCCTGGCTGAAGTCCCAAACCACGGTCAACTGGGTCGATAGCGAAGGCAACCCCACCGAACCGCCCACCCTTTCGCCCC
GCTCTGAGGGTGAAGACCGGCAGGAGAGGTCTGAGTCGGCTAGGGCAGGGGTGCCGGAGACGGAGTTTGAGGCCGAGAAG
CCAGAGGGATCCGCGATCCCCGAGGCAGTTGAGCCTCCTGTCGATGCGAAAGCTGAGGGGGAGGTTGCAACAGAGCCGCA
GGCAGCTCTCCCTTCTGTAGAAGCAGAGGCGTCTGGGATCCCTGAGGCGGTTGAGCCTTCTGCAGAGGCGGCCACAGACC
CTGCTGGCTTGCAACTGGAACAGGCCGTCGCGGAGACACCCAAAGCGGGCAAAAAGAGCAAAAAGGACAAGTAG

Upstream 100 bases:

>100_bases
TCCCCTGCCTAGAACTGTTCCGAATGGATCCCGTCGATCTCCAAGCAGTTGGGGTAAAATTGAAATTCTGCTTGCCTCTT
CCACTAGCCCATCACTTCCT

Downstream 100 bases:

>100_bases
AGGGTCCTGGTTGCCTCCCTAGACTTGCCGGTTCTCACACCTTGGCCGCCGGGGTCGGAAAAAGCCGGGCTACAAGAGGC
CGCGCCGCATCTGGTCCCAG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MQVTQEKRPGSRVGLKIVVEADQVKRSYEKTLRQLERNIQIPGFRKGKAPRNLVIRQVGRERVMASAVDDLINEAIQQAL
KDTQLHPISRFELDDKVEQLLDRFNPEADFSFSGYVEVYPEARVGQYKGLTVTATRVTVKPEQIDQLIDRWRDQRATLLP
VEDRPAQLGDVVVIDFQARDAEGNPLEEIAAQDFQLELKEENFIPGFVAGVVGMQLDQTKEITATFPDDYFRKELAGKTV
TFTVCLKEIKTKELPELDDAFVQEISEFQTVAELREHLQKRLEQDALRQSEENLETAILNAILETTEVDLPETLVEQETT
QLLARSLQSLQQQQGVTPGEIRKFLSQLPPETLNQLMERHRPEAINRLRRTLALSAIVRQEQIAVGPNELEVEVEEVMAA
YAQQGQKLDRERVRQAVHEDLLANKVMAWLKSQTTVNWVDSEGNPTEPPTLSPRSEGEDRQERSESARAGVPETEFEAEK
PEGSAIPEAVEPPVDAKAEGEVATEPQAALPSVEAEASGIPEAVEPSAEAATDPAGLQLEQAVAETPKAGKKSKKDK

Sequences:

>Translated_557_residues
MQVTQEKRPGSRVGLKIVVEADQVKRSYEKTLRQLERNIQIPGFRKGKAPRNLVIRQVGRERVMASAVDDLINEAIQQAL
KDTQLHPISRFELDDKVEQLLDRFNPEADFSFSGYVEVYPEARVGQYKGLTVTATRVTVKPEQIDQLIDRWRDQRATLLP
VEDRPAQLGDVVVIDFQARDAEGNPLEEIAAQDFQLELKEENFIPGFVAGVVGMQLDQTKEITATFPDDYFRKELAGKTV
TFTVCLKEIKTKELPELDDAFVQEISEFQTVAELREHLQKRLEQDALRQSEENLETAILNAILETTEVDLPETLVEQETT
QLLARSLQSLQQQQGVTPGEIRKFLSQLPPETLNQLMERHRPEAINRLRRTLALSAIVRQEQIAVGPNELEVEVEEVMAA
YAQQGQKLDRERVRQAVHEDLLANKVMAWLKSQTTVNWVDSEGNPTEPPTLSPRSEGEDRQERSESARAGVPETEFEAEK
PEGSAIPEAVEPPVDAKAEGEVATEPQAALPSVEAEASGIPEAVEPSAEAATDPAGLQLEQAVAETPKAGKKSKKDK
>Mature_557_residues
MQVTQEKRPGSRVGLKIVVEADQVKRSYEKTLRQLERNIQIPGFRKGKAPRNLVIRQVGRERVMASAVDDLINEAIQQAL
KDTQLHPISRFELDDKVEQLLDRFNPEADFSFSGYVEVYPEARVGQYKGLTVTATRVTVKPEQIDQLIDRWRDQRATLLP
VEDRPAQLGDVVVIDFQARDAEGNPLEEIAAQDFQLELKEENFIPGFVAGVVGMQLDQTKEITATFPDDYFRKELAGKTV
TFTVCLKEIKTKELPELDDAFVQEISEFQTVAELREHLQKRLEQDALRQSEENLETAILNAILETTEVDLPETLVEQETT
QLLARSLQSLQQQQGVTPGEIRKFLSQLPPETLNQLMERHRPEAINRLRRTLALSAIVRQEQIAVGPNELEVEVEEVMAA
YAQQGQKLDRERVRQAVHEDLLANKVMAWLKSQTTVNWVDSEGNPTEPPTLSPRSEGEDRQERSESARAGVPETEFEAEK
PEGSAIPEAVEPPVDAKAEGEVATEPQAALPSVEAEASGIPEAVEPSAEAATDPAGLQLEQAVAETPKAGKKSKKDK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

Organism=Escherichia coli, GI1786640, Length=402, Percent_Identity=25.6218905472637, Blast_Score=125, Evalue=7e-30,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_SYNJA (Q2JV31)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474684.1
- ProteinModelPortal:   Q2JV31
- STRING:   Q2JV31
- GeneID:   3899349
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_1238
- TIGR:   CYA_1238
- eggNOG:   COG0544
- HOGENOM:   HBG635105
- OMA:   NARLIQY
- ProtClustDB:   PRK01490
- BioCyc:   SSP321327:CYA_1238-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 62352; Mature: 62352

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVTQEKRPGSRVGLKIVVEADQVKRSYEKTLRQLERNIQIPGFRKGKAPRNLVIRQVGR
CCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ERVMASAVDDLINEAIQQALKDTQLHPISRFELDDKVEQLLDRFNPEADFSFSGYVEVYP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
EARVGQYKGLTVTATRVTVKPEQIDQLIDRWRDQRATLLPVEDRPAQLGDVVVIDFQARD
CCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEEECCC
AEGNPLEEIAAQDFQLELKEENFIPGFVAGVVGMQLDQTKEITATFPDDYFRKELAGKTV
CCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHCCCCC
TFTVCLKEIKTKELPELDDAFVQEISEFQTVAELREHLQKRLEQDALRQSEENLETAILN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILETTEVDLPETLVEQETTQLLARSLQSLQQQQGVTPGEIRKFLSQLPPETLNQLMERH
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHC
RPEAINRLRRTLALSAIVRQEQIAVGPNELEVEVEEVMAAYAQQGQKLDRERVRQAVHED
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLANKVMAWLKSQTTVNWVDSEGNPTEPPTLSPRSEGEDRQERSESARAGVPETEFEAEK
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
PEGSAIPEAVEPPVDAKAEGEVATEPQAALPSVEAEASGIPEAVEPSAEAATDPAGLQLE
CCCCCCCHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHCCCCHHCCCCHHHCCCCCCCHHH
QAVAETPKAGKKSKKDK
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQVTQEKRPGSRVGLKIVVEADQVKRSYEKTLRQLERNIQIPGFRKGKAPRNLVIRQVGR
CCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
ERVMASAVDDLINEAIQQALKDTQLHPISRFELDDKVEQLLDRFNPEADFSFSGYVEVYP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHHHCCCCCCCCCCCCEEECC
EARVGQYKGLTVTATRVTVKPEQIDQLIDRWRDQRATLLPVEDRPAQLGDVVVIDFQARD
CCCCCCCCCEEEEEEEEEECHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEEEECCC
AEGNPLEEIAAQDFQLELKEENFIPGFVAGVVGMQLDQTKEITATFPDDYFRKELAGKTV
CCCCCHHHHHHCCCEEEECCCCCCCHHHHHHHHCCCCCCCCCEECCCHHHHHHHHCCCCC
TFTVCLKEIKTKELPELDDAFVQEISEFQTVAELREHLQKRLEQDALRQSEENLETAILN
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AILETTEVDLPETLVEQETTQLLARSLQSLQQQQGVTPGEIRKFLSQLPPETLNQLMERH
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHC
RPEAINRLRRTLALSAIVRQEQIAVGPNELEVEVEEVMAAYAQQGQKLDRERVRQAVHED
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LLANKVMAWLKSQTTVNWVDSEGNPTEPPTLSPRSEGEDRQERSESARAGVPETEFEAEK
HHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
PEGSAIPEAVEPPVDAKAEGEVATEPQAALPSVEAEASGIPEAVEPSAEAATDPAGLQLE
CCCCCCCHHCCCCCCCCCCCCCCCCCHHHCCCCCHHHCCCCHHCCCCHHHCCCCCCCHHH
QAVAETPKAGKKSKKDK
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA