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The map label for this gene is dapL [H]

Identifier: 86605900

GI number: 86605900

Start: 1227848

End: 1229044

Strand: Reverse

Name: dapL [H]

Synonym: CYA_1216

Alternate gene names: 86605900

Gene position: 1229044-1227848 (Counterclockwise)

Preceding gene: 86605903

Following gene: 86605897

Centisome position: 41.91

GC content: 64.83

Gene sequence:

>1197_bases
ATGAACCGTGCCCTCGCCCCTGCCCAGCGGCTGAACAAACTGCCTGCCTATGTCTTTGCCCGCTTGGATGAGCTGAAGGC
CCGCGCCCGCCAGCAGGGGTTGGATTTGATCGATCTGGGCATGGGCAACCCCGATGGCCCCACCCCCCAGCCGGTGGTGG
AGGCGGCCCAGGCCGCCATTGCCGATCCCGCTCACCACGGCTACCCACCCTTCGAGGGCACGGCTAGCTTTCGCCAGGCA
ATTGCCGAGTGGTATTGGCGCCGCTACGGGGTGGAGCTGGATCCCAATGGCGAGGTGCTGCCTCTATTGGGATCCAAAGA
GGGCCTGACCCACCTGGCCCTGGCCTACGTGGATCCAGGGGATCTGGTGCTGGTGCCTAGCCCTGCCTACCCGCCCCATT
TTCGCGGTCCCCTGATTGCCGGCGGGCAGATCTACCCACTGCTGCTGCGCCCGGAGAAAGGATGGCTCATCGACCTGCAA
GAGATCCCGCCGGAGGTGGCCAAGCAGGCGCGGCTGCTCTACTTCAACTACCCCAACAACCCGACAACAGCGGTGGCGAC
CCGCTCCTTTTTTGAAGCAGTGGTGGCGTTTGCTTGCCGCTACGACCTCCTCCTGGTGCACGACCTGTGCTATGCCGAGC
TGGCCTTTGACGGCTACCGGCCCACCAGCCTGCTGCAGATCCCTGGCGCCAAGGACTTGGCCGTGGAGTTCCACACCCTC
TCCAAAACCTACAACATGGCCGGTTGGCGGGTAGGCTTTGTGGTGGGCAACCGCCAGATTATCCAGAGCCTGCGCACCCT
GAAAACCAACCTCGACTACGGCATTTTTGGCGCCCTGCAAAAGGCGGCCGAGACCGCTTTGGCCTTGCCAGATAGCTACC
TACAGCAGGTGCAGGAGCGCTACCGCCGCCGACGCGACTACCTCATTGCCCGCCTGGCCGAGTTGGGCTGGCAGATCGAG
CCGCCGCGGGCGACGATGTACCTCTGGATCCCGACCCCCCGCACCGCCGACGGCACGCCCGAGGGATCGACGGAGTTTGC
CCTGCGGGTTTTGGAGTCCACCGGGGTGGTGGTGACTCCCGGCAACGCCTTTGGGGAAGGGGGAGAAGGCTACGTGCGGA
TCAGCCTGATTGCCGATTGCGAACGCCTGGGCCAGGCCATCGACCGCTGGGCAGAAGCCGGGATCCGCTATTGCTGA

Upstream 100 bases:

>100_bases
ACCCGCTGATCTCAATCATTGCCCTGAAGGCAGCTCTGGCGGTAAGTTAGGTAGCTAACCTCCCATCAGACACCGGCTGC
ACTCGTTTCCCCTCCTTGCT

Downstream 100 bases:

>100_bases
GCTCTAGGGTTGGCCCTCTCCCCTAGGGAGAGGGGAGTTGGTATTGCTCCACGATGCGCCGGGCAAAAGGAGGCACATGC
TGCTCCAACTTGTGGGGATA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNRALAPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAIADPAHHGYPPFEGTASFRQA
IAEWYWRRYGVELDPNGEVLPLLGSKEGLTHLALAYVDPGDLVLVPSPAYPPHFRGPLIAGGQIYPLLLRPEKGWLIDLQ
EIPPEVAKQARLLYFNYPNNPTTAVATRSFFEAVVAFACRYDLLLVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFGALQKAAETALALPDSYLQQVQERYRRRRDYLIARLAELGWQIE
PPRATMYLWIPTPRTADGTPEGSTEFALRVLESTGVVVTPGNAFGEGGEGYVRISLIADCERLGQAIDRWAEAGIRYC

Sequences:

>Translated_398_residues
MNRALAPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAIADPAHHGYPPFEGTASFRQA
IAEWYWRRYGVELDPNGEVLPLLGSKEGLTHLALAYVDPGDLVLVPSPAYPPHFRGPLIAGGQIYPLLLRPEKGWLIDLQ
EIPPEVAKQARLLYFNYPNNPTTAVATRSFFEAVVAFACRYDLLLVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFGALQKAAETALALPDSYLQQVQERYRRRRDYLIARLAELGWQIE
PPRATMYLWIPTPRTADGTPEGSTEFALRVLESTGVVVTPGNAFGEGGEGYVRISLIADCERLGQAIDRWAEAGIRYC
>Mature_398_residues
MNRALAPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAIADPAHHGYPPFEGTASFRQA
IAEWYWRRYGVELDPNGEVLPLLGSKEGLTHLALAYVDPGDLVLVPSPAYPPHFRGPLIAGGQIYPLLLRPEKGWLIDLQ
EIPPEVAKQARLLYFNYPNNPTTAVATRSFFEAVVAFACRYDLLLVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFGALQKAAETALALPDSYLQQVQERYRRRRDYLIARLAELGWQIE
PPRATMYLWIPTPRTADGTPEGSTEFALRVLESTGVVVTPGNAFGEGGEGYVRISLIADCERLGQAIDRWAEAGIRYC

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=386, Percent_Identity=25.6476683937824, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI169881279, Length=386, Percent_Identity=25.6476683937824, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI56713256, Length=332, Percent_Identity=24.3975903614458, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI56713254, Length=332, Percent_Identity=24.3975903614458, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI169881281, Length=374, Percent_Identity=23.7967914438503, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=23.8726790450928, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=45.7894736842105, Blast_Score=346, Evalue=1e-96,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=27.4725274725275, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788627, Length=263, Percent_Identity=28.1368821292776, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=394, Percent_Identity=23.8578680203046, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=394, Percent_Identity=23.8578680203046, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=314, Percent_Identity=23.5668789808917, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=388, Percent_Identity=24.2268041237113, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=387, Percent_Identity=21.7054263565891, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6320317, Length=353, Percent_Identity=25.7790368271955, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=386, Percent_Identity=25.3886010362694, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24646114, Length=386, Percent_Identity=25.3886010362694, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573067, Length=386, Percent_Identity=25.3886010362694, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573065, Length=386, Percent_Identity=25.3886010362694, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI18859735, Length=391, Percent_Identity=25.5754475703325, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44164; Mature: 44164

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRALAPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAI
CCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHH
ADPAHHGYPPFEGTASFRQAIAEWYWRRYGVELDPNGEVLPLLGSKEGLTHLALAYVDPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCCCEEEEEEECCC
DLVLVPSPAYPPHFRGPLIAGGQIYPLLLRPEKGWLIDLQEIPPEVAKQARLLYFNYPNN
CEEEECCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEHHHCCHHHHCCCEEEEEECCCC
PTTAVATRSFFEAVVAFACRYDLLLVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEHH
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFGALQKAAETALALPDSYLQQVQER
HHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YRRRRDYLIARLAELGWQIEPPRATMYLWIPTPRTADGTPEGSTEFALRVLESTGVVVTP
HHHHHHHHHHHHHHHCCEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEC
GNAFGEGGEGYVRISLIADCERLGQAIDRWAEAGIRYC
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRALAPAQRLNKLPAYVFARLDELKARARQQGLDLIDLGMGNPDGPTPQPVVEAAQAAI
CCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHH
ADPAHHGYPPFEGTASFRQAIAEWYWRRYGVELDPNGEVLPLLGSKEGLTHLALAYVDPG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCEEEECCCCCCCCEEEEEEECCC
DLVLVPSPAYPPHFRGPLIAGGQIYPLLLRPEKGWLIDLQEIPPEVAKQARLLYFNYPNN
CEEEECCCCCCCCCCCCEEECCCEEEEEEECCCCCEEEHHHCCHHHHCCCEEEEEECCCC
PTTAVATRSFFEAVVAFACRYDLLLVHDLCYAELAFDGYRPTSLLQIPGAKDLAVEFHTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEHH
SKTYNMAGWRVGFVVGNRQIIQSLRTLKTNLDYGIFGALQKAAETALALPDSYLQQVQER
HHHHCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
YRRRRDYLIARLAELGWQIEPPRATMYLWIPTPRTADGTPEGSTEFALRVLESTGVVVTP
HHHHHHHHHHHHHHHCCEECCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCEEEEC
GNAFGEGGEGYVRISLIADCERLGQAIDRWAEAGIRYC
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA