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The map label for this gene is mpg1 [H]

Identifier: 86605380

GI number: 86605380

Start: 677064

End: 678011

Strand: Reverse

Name: mpg1 [H]

Synonym: CYA_0667

Alternate gene names: 86605380

Gene position: 678011-677064 (Counterclockwise)

Preceding gene: 86605381

Following gene: 86605379

Centisome position: 23.12

GC content: 62.03

Gene sequence:

>948_bases
ATGCAGGCGGTGATTTTGGCAGGGGGGCAAGGAACTCGCTTACGGCCGCTGACCTTGTGGCAACCGAAGCCTCTGCTGCC
GTTGCTAGAGGTGCCTTTTTTACACTGGCTGATCGGGCGCTGCCGCCGGGCCGGCCTGACGGACATTTTGCTCAGCGTGG
GGTATCTGGGCAGACAGATCGAGGCGGCTCTGGGAGATGGCACTGCTTGGGGGGTAAAGCTCCGCTACGTCGTCGAGGAG
ACGCCGCTAGATACAGCGGGAGCTTTGGTGCTGGCCCAACCCTACTTCAGCGGGGATCCCTTAGTGGTCTTCAATGCCGA
TATCCTCACCGATCTGGATTTATTAGATTTGATACACTGCCACCTGCAGAGCGGGGCCGTCGCCACCCTCACCCTCGCCC
AGGTGGAGGACGTCACCGCCTACGGCCTGGTGGAGGTAGGGGAAGGGGGCCGGATCCAATCCTTTCGGGAAAAGCCCACT
GCTGCCGAAGCCCTCACCCTCACCACCAACACCATCAACGCTGGTACCTATGTCCTCGATCCGGCTATTTTCAAAGACTA
CCCCAGCGGGGATCCCCTCAGCTTCGAGCGGCGTATCTTCCCCGACTTGCTGCGGCAGGGGCGACGGCTGCAAGCCTACC
TGCACACTGGCTACTGGCGGGATCTGGGCACGCCGGCCAGCTACTACCACGGCCAACTGGACATTCTCCTGAGCCGGATG
AGGGATTTCCCTCTCGAGGATGTGGAAGAACGGGCGCCAGGGGTATGGGTTCACAAGACCGCCGAGATCCACCCTGACGT
TCAATTGCACGCGCCCTGCTACATCGGCGCTTACACGCGCTTGGGCTCCCAAGCTCAAGTCCCCGCCGGCACCATCCTCG
GCAGCTACAGTTGGGTCAATGGATCCCTGCAGCCGGGGGCCTATGGGCCGGGCCTCCTGGTAGTCTAG

Upstream 100 bases:

>100_bases
AAGGGGGGCTCTCCCTGCCTCTGGCCTCAGCCAGTTGGCTGTGGCAGGCTGGATCCTTTTCCCCTACCATCTAGGCTGGG
AAAATGGGTTGGGGATAGCT

Downstream 100 bases:

>100_bases
GTTAAAGGCCAGTTAAGCGCCCAAGCCTCCACAACAGAGCCGGCCAAAGATGGAGCTACCGCAAAGCGGGGAACGCTGGG
ATCCCTATCTTGCCGCCGTA

Product: nucleotidyl transferase family protein

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQAVILAGGQGTRLRPLTLWQPKPLLPLLEVPFLHWLIGRCRRAGLTDILLSVGYLGRQIEAALGDGTAWGVKLRYVVEE
TPLDTAGALVLAQPYFSGDPLVVFNADILTDLDLLDLIHCHLQSGAVATLTLAQVEDVTAYGLVEVGEGGRIQSFREKPT
AAEALTLTTNTINAGTYVLDPAIFKDYPSGDPLSFERRIFPDLLRQGRRLQAYLHTGYWRDLGTPASYYHGQLDILLSRM
RDFPLEDVEERAPGVWVHKTAEIHPDVQLHAPCYIGAYTRLGSQAQVPAGTILGSYSWVNGSLQPGAYGPGLLVV

Sequences:

>Translated_315_residues
MQAVILAGGQGTRLRPLTLWQPKPLLPLLEVPFLHWLIGRCRRAGLTDILLSVGYLGRQIEAALGDGTAWGVKLRYVVEE
TPLDTAGALVLAQPYFSGDPLVVFNADILTDLDLLDLIHCHLQSGAVATLTLAQVEDVTAYGLVEVGEGGRIQSFREKPT
AAEALTLTTNTINAGTYVLDPAIFKDYPSGDPLSFERRIFPDLLRQGRRLQAYLHTGYWRDLGTPASYYHGQLDILLSRM
RDFPLEDVEERAPGVWVHKTAEIHPDVQLHAPCYIGAYTRLGSQAQVPAGTILGSYSWVNGSLQPGAYGPGLLVV
>Mature_315_residues
MQAVILAGGQGTRLRPLTLWQPKPLLPLLEVPFLHWLIGRCRRAGLTDILLSVGYLGRQIEAALGDGTAWGVKLRYVVEE
TPLDTAGALVLAQPYFSGDPLVVFNADILTDLDLLDLIHCHLQSGAVATLTLAQVEDVTAYGLVEVGEGGRIQSFREKPT
AAEALTLTTNTINAGTYVLDPAIFKDYPSGDPLSFERRIFPDLLRQGRRLQAYLHTGYWRDLGTPASYYHGQLDILLSRM
RDFPLEDVEERAPGVWVHKTAEIHPDVQLHAPCYIGAYTRLGSQAQVPAGTILGSYSWVNGSLQPGAYGPGLLVV

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=318, Percent_Identity=30.8176100628931, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI11761619, Length=297, Percent_Identity=31.986531986532, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI31881779, Length=329, Percent_Identity=27.355623100304, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI45447090, Length=329, Percent_Identity=27.355623100304, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1788351, Length=233, Percent_Identity=31.3304721030043, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790224, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787488, Length=272, Percent_Identity=26.1029411764706, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI133931050, Length=323, Percent_Identity=33.4365325077399, Blast_Score=161, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17509979, Length=315, Percent_Identity=29.2063492063492, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17509981, Length=304, Percent_Identity=28.2894736842105, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320148, Length=316, Percent_Identity=30.6962025316456, Blast_Score=135, Evalue=7e-33,
Organism=Drosophila melanogaster, GI21355443, Length=320, Percent_Identity=31.25, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24644084, Length=320, Percent_Identity=31.25, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24653912, Length=201, Percent_Identity=34.8258706467662, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 34452; Mature: 34452

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVILAGGQGTRLRPLTLWQPKPLLPLLEVPFLHWLIGRCRRAGLTDILLSVGYLGRQI
CCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EAALGDGTAWGVKLRYVVEETPLDTAGALVLAQPYFSGDPLVVFNADILTDLDLLDLIHC
HHHHCCCCEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECHHHCCHHHHHHHHH
HLQSGAVATLTLAQVEDVTAYGLVEVGEGGRIQSFREKPTAAEALTLTTNTINAGTYVLD
HHCCCCEEEEEEEHHHCCCEEEEEEECCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEC
PAIFKDYPSGDPLSFERRIFPDLLRQGRRLQAYLHTGYWRDLGTPASYYHGQLDILLSRM
HHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHCCCCCHHHHCCHHHHHHHHH
RDFPLEDVEERAPGVWVHKTAEIHPDVQLHAPCYIGAYTRLGSQAQVPAGTILGSYSWVN
HCCCCHHHHHHCCCEEEEEEECCCCCEEEECCEEEEHHHHCCCCCCCCCHHEEECEEEEC
GSLQPGAYGPGLLVV
CCCCCCCCCCCEEEC
>Mature Secondary Structure
MQAVILAGGQGTRLRPLTLWQPKPLLPLLEVPFLHWLIGRCRRAGLTDILLSVGYLGRQI
CCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
EAALGDGTAWGVKLRYVVEETPLDTAGALVLAQPYFSGDPLVVFNADILTDLDLLDLIHC
HHHHCCCCEEEEEEEEEEECCCCCCCCEEEEECCCCCCCCEEEEECHHHCCHHHHHHHHH
HLQSGAVATLTLAQVEDVTAYGLVEVGEGGRIQSFREKPTAAEALTLTTNTINAGTYVLD
HHCCCCEEEEEEEHHHCCCEEEEEEECCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEC
PAIFKDYPSGDPLSFERRIFPDLLRQGRRLQAYLHTGYWRDLGTPASYYHGQLDILLSRM
HHHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHCCCCCHHHHCCHHHHHHHHH
RDFPLEDVEERAPGVWVHKTAEIHPDVQLHAPCYIGAYTRLGSQAQVPAGTILGSYSWVN
HCCCCHHHHHHCCCEEEEEEECCCCCEEEECCEEEEHHHHCCCCCCCCCHHEEECEEEEC
GSLQPGAYGPGLLVV
CCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]