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The map label for this gene is purQ

Identifier: 86605361

GI number: 86605361

Start: 656914

End: 657591

Strand: Reverse

Name: purQ

Synonym: CYA_0646

Alternate gene names: 86605361

Gene position: 657591-656914 (Counterclockwise)

Preceding gene: 86605362

Following gene: 86605357

Centisome position: 22.42

GC content: 64.01

Gene sequence:

>678_bases
ATGGCTAAGGTAAGGTTTGGCATTGTCGTTTTCCCCGGTTCCAATTGTGACCGCGACGTGGCCTGGGTAACCCGCGGCCT
CTTGGGCTGCCCGACGCGACTCATCTGGCACCGGGAAACCGATTTATCGGGGCTGGATGTGGTGGTGCTGCCAGGGGGCT
TCAGCTACGGGGATTATCTACGAGCTGGGGCGCTGGCCCGTTTTGCGCCAGTGATGGGATCCCTGGCCGAGCATGGGGCG
CGGGGGGGCTATGTCCTGGGCATTTGCAACGGCTTCCAGATCTTGACAGAAGCCGGTCTGCTGCCGGGGGCGCTGGTGCG
CAACGCCAACCTGCACTTTATCTGCGACCGGGTAGGGATCCGCGTGGAGCGGCAAGACCTGCCCTGGACCAGCGCTTACC
CTTGCGGAGCCACCCTGACCCTGCCCATCGCCCATGGGGAAGGCCGCTACGTCTGCGATGCCGATACCCTCAAGCAGTTG
CAGGACAGGGGGCAGATCGTCTTTCGCTATGCTCCGGTCGCGCCCAATGGCTCGGTGGACAACATCGCCGGCATTTGTGA
CCCTAGCGGTCGCATCCTCGGCCTGATGCCTCACCCGGAGCGGGCGGCGGATCCCGACTTGCCGGGGCAGGATGGGATCC
CCTTTTGGCAGTCCATTGTCCAAAGCCTGGCCGGTTAG

Upstream 100 bases:

>100_bases
CCGGTCATCGAGACCTATCAAATCCAAGTGGATCCTGTAGAGAGTTGATTGCTCACGCCTAGCCCTCACCACCTTTTTGT
TTTCACAGCAAGGGATCCCC

Downstream 100 bases:

>100_bases
CCCTGCTGGGCCTGAGCCAACACCCTGCGCACCTGGTTCACCATCTCCTCGTGATCCACCACCGGCTTGGCGATGTAGCC
ATTGGCCCCACTTTGAGCCA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAKVRFGIVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSGLDVVVLPGGFSYGDYLRAGALARFAPVMGSLAEHGA
RGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPCGATLTLPIAHGEGRYVCDADTLKQL
QDRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSIVQSLAG

Sequences:

>Translated_225_residues
MAKVRFGIVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSGLDVVVLPGGFSYGDYLRAGALARFAPVMGSLAEHGA
RGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPCGATLTLPIAHGEGRYVCDADTLKQL
QDRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSIVQSLAG
>Mature_224_residues
AKVRFGIVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSGLDVVVLPGGFSYGDYLRAGALARFAPVMGSLAEHGAR
GGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGIRVERQDLPWTSAYPCGATLTLPIAHGEGRYVCDADTLKQLQ
DRGQIVFRYAPVAPNGSVDNIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSIVQSLAG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=185, Percent_Identity=32.4324324324324, Blast_Score=70, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=185, Percent_Identity=32.4324324324324, Blast_Score=79, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24582111, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582109, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137292, Length=190, Percent_Identity=30.5263157894737, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_SYNJA (Q2JWK2)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474124.1
- ProteinModelPortal:   Q2JWK2
- SMR:   Q2JWK2
- STRING:   Q2JWK2
- GeneID:   3897284
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0646
- TIGR:   CYA_0646
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   HPENHVE
- ProtClustDB:   PRK03619
- BioCyc:   SSP321327:CYA_0646-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 24108; Mature: 23977

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 89-89 ACT_SITE 198-198 ACT_SITE 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVRFGIVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSGLDVVVLPGGFSYGDYL
CCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCHHHHH
RAGALARFAPVMGSLAEHGARGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGI
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCHHHCCCCEEEEEECCCC
RVERQDLPWTSAYPCGATLTLPIAHGEGRYVCDADTLKQLQDRGQIVFRYAPVAPNGSVD
EEECCCCCCCCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCC
NIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSIVQSLAG
CCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AKVRFGIVVFPGSNCDRDVAWVTRGLLGCPTRLIWHRETDLSGLDVVVLPGGFSYGDYL
CEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCHHHHH
RAGALARFAPVMGSLAEHGARGGYVLGICNGFQILTEAGLLPGALVRNANLHFICDRVGI
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHCCCCCCHHHCCCCEEEEEECCCC
RVERQDLPWTSAYPCGATLTLPIAHGEGRYVCDADTLKQLQDRGQIVFRYAPVAPNGSVD
EEECCCCCCCCCCCCCCEEEEEEECCCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCC
NIAGICDPSGRILGLMPHPERAADPDLPGQDGIPFWQSIVQSLAG
CCCEEECCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA