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The map label for this gene is trpD

Identifier: 86605344

GI number: 86605344

Start: 641898

End: 642929

Strand: Reverse

Name: trpD

Synonym: CYA_0630

Alternate gene names: 86605344

Gene position: 642929-641898 (Counterclockwise)

Preceding gene: 86605345

Following gene: 86605342

Centisome position: 21.92

GC content: 63.86

Gene sequence:

>1032_bases
ATGACGGAAACGGCTGACCTTTGGCCCCAGCTTTTGGGACAGTTGCTGGAGCGGCAATCTCTGAGCGAAGCCCAAGCCGA
ACAGTTGATGAACGGCTGGCTGCACAACCAAGTGCCGGATGTGGTGTCGGGAGCGATTTTGGCGGCCCTGCAAGCCAAGG
GGGTCAGCGCCAGTGAACTGGCCGGCATGGCGCGGGTGCTGCAGCGAGCTTCCCTGGGATCCCCCCTGGATCTGCCCCTG
TTGGTGGATACTTGCGGCACCGGGGGAGATGGGGCCGGCACGTTTAACATTTCCACTGCCGTGGCCTTCGTGGTCAGCGC
TGCCGGGATCCCAGTCGTGAAGCACGGCAACCGCTCTGCTTCTGGCAAGGTTGGCTCGGCGGACGTGCTGGAGGCGTTGG
GGGTGAACCTGAGCGCTGAGCCAGAGCAAGTGCGGGCGGCGGTGGCGGAAGTGGGCATCACCTTTCTCTTTGCCCCCCAC
TGGCACCCGGCCATGCGGGCGGTGATCCCCTACCGCCGCGCCCTTAAAGTTCGCACTGTCTTTAATCTCTTGGGGCCCCT
GGTCAATCCCCTCTATCCCAACCGCCAGGTGATCGGGGTTTATGCCCCGGAGCTGGTGCCGGTGATGGCCGAGGCCTTGC
GTCTGTTGGGGCGGGAAAGGGCCGTGGTGTTGCACAGCCGCGAAGGTCTGGACGAGGCCGGGTTGGATCAGCCCACCGAT
CTGGGCATCCTTTCCGGTGGGCTGGTACGAACAGAAGTTTTGAACCCGCGAGATTACGATCTTACGCCCGCACCTGTCCA
GGCCCTCCAGGGGGGGAACTTGGCGGAAAATGCCGCCATCCTCGCCCAAGTTCTCCAAGGATCCGGAGCGCCTGCCCAGC
GGGATGTGGTGGCCCTCAATGCCGCTTTGGCCCTGCAGGTGGCCGGAGCCGTTCCCGATTGGGGATCCGGAATTGCCCAA
GCGCGGGAGATCCTTGCCAGCGGCGCTGCCTGGGATCGCCTGCAAAAGCTGGTCAATTTTCTGGCTTCGTGA

Upstream 100 bases:

>100_bases
CTCGGACCCTTGGCTGCGCGATCTCTAGCCGCTTTGGCCGAAAGAGCCCCCGCAGACCTATGCTAGGATGAGGGCTTGCT
GAAAACCCGGATCCCGCCCC

Downstream 100 bases:

>100_bases
CGTACTCCCGCACTCATGCTGACGCATAGAGTGCGGGCTTCCCAGTGACTCCTGCCCAATAGCAGGACATTTCCTGAGCT
TGAAGAACGGGACGCCCCAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTETADLWPQLLGQLLERQSLSEAQAEQLMNGWLHNQVPDVVSGAILAALQAKGVSASELAGMARVLQRASLGSPLDLPL
LVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLSAEPEQVRAAVAEVGITFLFAPH
WHPAMRAVIPYRRALKVRTVFNLLGPLVNPLYPNRQVIGVYAPELVPVMAEALRLLGRERAVVLHSREGLDEAGLDQPTD
LGILSGGLVRTEVLNPRDYDLTPAPVQALQGGNLAENAAILAQVLQGSGAPAQRDVVALNAALALQVAGAVPDWGSGIAQ
AREILASGAAWDRLQKLVNFLAS

Sequences:

>Translated_343_residues
MTETADLWPQLLGQLLERQSLSEAQAEQLMNGWLHNQVPDVVSGAILAALQAKGVSASELAGMARVLQRASLGSPLDLPL
LVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLSAEPEQVRAAVAEVGITFLFAPH
WHPAMRAVIPYRRALKVRTVFNLLGPLVNPLYPNRQVIGVYAPELVPVMAEALRLLGRERAVVLHSREGLDEAGLDQPTD
LGILSGGLVRTEVLNPRDYDLTPAPVQALQGGNLAENAAILAQVLQGSGAPAQRDVVALNAALALQVAGAVPDWGSGIAQ
AREILASGAAWDRLQKLVNFLAS
>Mature_342_residues
TETADLWPQLLGQLLERQSLSEAQAEQLMNGWLHNQVPDVVSGAILAALQAKGVSASELAGMARVLQRASLGSPLDLPLL
VDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSASGKVGSADVLEALGVNLSAEPEQVRAAVAEVGITFLFAPHW
HPAMRAVIPYRRALKVRTVFNLLGPLVNPLYPNRQVIGVYAPELVPVMAEALRLLGRERAVVLHSREGLDEAGLDQPTDL
GILSGGLVRTEVLNPRDYDLTPAPVQALQGGNLAENAAILAQVLQGSGAPAQRDVVALNAALALQVAGAVPDWGSGIAQA
REILASGAAWDRLQKLVNFLAS

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=335, Percent_Identity=40.8955223880597, Blast_Score=223, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6320561, Length=283, Percent_Identity=31.8021201413428, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_SYNJA (Q2JWL5)

Other databases:

- EMBL:   CP000239
- RefSeq:   YP_474107.1
- HSSP:   P50384
- ProteinModelPortal:   Q2JWL5
- SMR:   Q2JWL5
- STRING:   Q2JWL5
- GeneID:   3897305
- GenomeReviews:   CP000239_GR
- KEGG:   cya:CYA_0630
- TIGR:   CYA_0630
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- ProtClustDB:   PRK00188
- BioCyc:   SSP321327:CYA_0630-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 35796; Mature: 35664

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETADLWPQLLGQLLERQSLSEAQAEQLMNGWLHNQVPDVVSGAILAALQAKGVSASEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
AGMARVLQRASLGSPLDLPLLVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSA
HHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCC
SGKVGSADVLEALGVNLSAEPEQVRAAVAEVGITFLFAPHWHPAMRAVIPYRRALKVRTV
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCHHEEECCCCCHHHHHHHHHHHHHHHHHH
FNLLGPLVNPLYPNRQVIGVYAPELVPVMAEALRLLGRERAVVLHSREGLDEAGLDQPTD
HHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
LGILSGGLVRTEVLNPRDYDLTPAPVQALQGGNLAENAAILAQVLQGSGAPAQRDVVALN
CHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
AALALQVAGAVPDWGSGIAQAREILASGAAWDRLQKLVNFLAS
HHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TETADLWPQLLGQLLERQSLSEAQAEQLMNGWLHNQVPDVVSGAILAALQAKGVSASEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
AGMARVLQRASLGSPLDLPLLVDTCGTGGDGAGTFNISTAVAFVVSAAGIPVVKHGNRSA
HHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCEEHHHHHHHHHHHHCCCCEEECCCCCC
SGKVGSADVLEALGVNLSAEPEQVRAAVAEVGITFLFAPHWHPAMRAVIPYRRALKVRTV
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHCHHEEECCCCCHHHHHHHHHHHHHHHHHH
FNLLGPLVNPLYPNRQVIGVYAPELVPVMAEALRLLGRERAVVLHSREGLDEAGLDQPTD
HHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCC
LGILSGGLVRTEVLNPRDYDLTPAPVQALQGGNLAENAAILAQVLQGSGAPAQRDVVALN
CHHHCCCEEEEEECCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
AALALQVAGAVPDWGSGIAQAREILASGAAWDRLQKLVNFLAS
HHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA