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The map label for this gene is ubiB [C]

Identifier: 86604937

GI number: 86604937

Start: 220040

End: 221776

Strand: Reverse

Name: ubiB [C]

Synonym: CYA_0213

Alternate gene names: 86604937

Gene position: 221776-220040 (Counterclockwise)

Preceding gene: 86604938

Following gene: 86604936

Centisome position: 7.56

GC content: 60.62

Gene sequence:

>1737_bases
TTGAACGCCAGCACACTCCCATCCCGAGCCGTTTTGGGATCCGAACCCGCCAAGCCCTATACCGCCTACCGTTGGGCCCG
AGAAAACTACACCCGCTGGGGCCGCCTCATTGATATTTGGCGATTTGTGCTCACCTGGCTGTTTTACCTCTGGCTGGATC
AGCAGGCGTGGAGCTACGGGGGGCAGCCCACAGCGGAGCGCAAAGCCAAACGCCGCCGCGCCAGGGCCATCTGGATCCGC
GAGACGCTGCTCCACCTCGGTCCTACTTTTATCAAGGTGGGGCAGTTTTTCTCCACCCGGGCCGATCTCTTCCCCTCCGA
GTACGTCGAGGAGCTGTCCAAGCTGCAGGATCGGGTGCCTGCTTTTGGCTACGAACAGGTGGCAGCCATCGTGCAGCAAG
AGTTGGGCAAGCCCATTGAGCAGATCTACAGCTATTTCGATCCCACCCCCTTGGCGGCGGCCAGCTTGGGGCAGGTGCAT
CGGGCCAAGCTCAAGACCGGCGAAGAAGTGGTGGTCAAGGTGCAGCGTCCGGGCCTGACCCGCCTGTTCACGATCGATCT
GGAGATCTGCCGCGGTATTGCCGAGTTCTTTCAGTACCACACCCGTTGGGGCGGGCCGGGCCGCGACTGGATCGGCATCT
ACGAAGAGTGTCGGCGCACCCTCTGGGAGGAAGTGGACTACCTCAACGAGGGCCGCAACGCCGACACCTTTCGCCGCAAC
TTTCGGGACATGCCACAAATTGCCGTCCCCAAAGTGTACTGGCGCTACACTTCCCCCCGCCTGCTGACGCTGGAATACCT
GCCAGGGATCAAGATCAGCGACTACGAAGCCCTGAGCGCGGCGGGGCTGGATCGCAAGCTCTTGGCCCGCTTGGGGGCAG
AGGCCTATTTGCGGCAACTGCTCAAAGACGGCTTTTTTCACGCCGATCCCCACCCTGGCAACATTGCCGTCAAGCCGGAT
GGCACGCTGATCTTCTACGACTTCGGCATGATGGGGCGCATTCGCCCTGGCATCAAGGGAAAGTTGGTGGCCATGCTGGC
GGCTGTGGTGGCCAAAAATGCCGACCTGGTGGTGGCCTCGCTGGTGGAGCTGGGCGTGTTGGTGCCCACTGCCGATCTGG
CGCCAGTACGCCGCTCGGTGCAGTACATGTTGGATCACTTCATGGACAAGCCCTTTTCCAACAGCTCCGACGAGATCTCG
GTGATGGCCATCAGCGAAGACCTCTACGAGCTGGCCTACGATCAGCCGTTTCGCTTTCCCGCCACCTTTACCTTTGTGAT
GCGGGCCCTGACCACGTTGGAGGGGCTGGGGAAAAGCTTGGATCCGGAGTTCAATTTCCTGGAAGTGGCCAAGCCTTTCG
CGGAGGAGCTGATGAACGGTAGCAAACCGGAGACGGAGACTCTGCTAGCCCAGGTCAGCCGCCAGGCGGCAGAGTTCACC
AGCAGCAGCCTCAGCTTGCCCCGCCGTCTTGAAGCGACCTTGAGCAAGCTGGAACAGGGGGAGCTACGCCTGCGGGTGCG
ATCCAGCGAGGCAGAGCGTTTGCTGCGCAAGCTGAACAGCACCGGACGGGGAGTTATCTACGCGGTGTTGTTTGCAACTT
TTTTTCTCAGCGCAACCCAGCTATTTTCGGCTGGGCATGCTACTTTAGCGATCGTCACCCTGGCTTTGGCCGTTCTCGCC
GCTTTGGCGCTGGTCAGGGTACTCTTAAAGGCAAATGGATCAGAGCCACTGATGTGA

Upstream 100 bases:

>100_bases
CCCCCTTCAAGGCAGAAGACCTGCAGGCAACCCTAGACGACCTGCGGGCAGAGGTGGCGCAGTTGCGCTCCGAATTGCAG
AAGTATCGGAGTCGAAACGC

Downstream 100 bases:

>100_bases
TGCGACGATATGCCTGCGCTACGGATCCAGGCAAGGTCCGCAGCAGCAATCAGGATGCCTACTACTGTGATCCAGAAGGA
CGTTACTTCATCGTTGCCGA

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MNASTLPSRAVLGSEPAKPYTAYRWARENYTRWGRLIDIWRFVLTWLFYLWLDQQAWSYGGQPTAERKAKRRRARAIWIR
ETLLHLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVPAFGYEQVAAIVQQELGKPIEQIYSYFDPTPLAAASLGQVH
RAKLKTGEEVVVKVQRPGLTRLFTIDLEICRGIAEFFQYHTRWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRN
FRDMPQIAVPKVYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKLLARLGAEAYLRQLLKDGFFHADPHPGNIAVKPD
GTLIFYDFGMMGRIRPGIKGKLVAMLAAVVAKNADLVVASLVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSNSSDEIS
VMAISEDLYELAYDQPFRFPATFTFVMRALTTLEGLGKSLDPEFNFLEVAKPFAEELMNGSKPETETLLAQVSRQAAEFT
SSSLSLPRRLEATLSKLEQGELRLRVRSSEAERLLRKLNSTGRGVIYAVLFATFFLSATQLFSAGHATLAIVTLALAVLA
ALALVRVLLKANGSEPLM

Sequences:

>Translated_578_residues
MNASTLPSRAVLGSEPAKPYTAYRWARENYTRWGRLIDIWRFVLTWLFYLWLDQQAWSYGGQPTAERKAKRRRARAIWIR
ETLLHLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVPAFGYEQVAAIVQQELGKPIEQIYSYFDPTPLAAASLGQVH
RAKLKTGEEVVVKVQRPGLTRLFTIDLEICRGIAEFFQYHTRWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRN
FRDMPQIAVPKVYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKLLARLGAEAYLRQLLKDGFFHADPHPGNIAVKPD
GTLIFYDFGMMGRIRPGIKGKLVAMLAAVVAKNADLVVASLVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSNSSDEIS
VMAISEDLYELAYDQPFRFPATFTFVMRALTTLEGLGKSLDPEFNFLEVAKPFAEELMNGSKPETETLLAQVSRQAAEFT
SSSLSLPRRLEATLSKLEQGELRLRVRSSEAERLLRKLNSTGRGVIYAVLFATFFLSATQLFSAGHATLAIVTLALAVLA
ALALVRVLLKANGSEPLM
>Mature_578_residues
MNASTLPSRAVLGSEPAKPYTAYRWARENYTRWGRLIDIWRFVLTWLFYLWLDQQAWSYGGQPTAERKAKRRRARAIWIR
ETLLHLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVPAFGYEQVAAIVQQELGKPIEQIYSYFDPTPLAAASLGQVH
RAKLKTGEEVVVKVQRPGLTRLFTIDLEICRGIAEFFQYHTRWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRN
FRDMPQIAVPKVYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKLLARLGAEAYLRQLLKDGFFHADPHPGNIAVKPD
GTLIFYDFGMMGRIRPGIKGKLVAMLAAVVAKNADLVVASLVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSNSSDEIS
VMAISEDLYELAYDQPFRFPATFTFVMRALTTLEGLGKSLDPEFNFLEVAKPFAEELMNGSKPETETLLAQVSRQAAEFT
SSSLSLPRRLEATLSKLEQGELRLRVRSSEAERLLRKLNSTGRGVIYAVLFATFFLSATQLFSAGHATLAIVTLALAVLA
ALALVRVLLKANGSEPLM

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=285, Percent_Identity=32.6315789473684, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI40254938, Length=277, Percent_Identity=30.3249097472924, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI217035081, Length=245, Percent_Identity=29.7959183673469, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI32261307, Length=340, Percent_Identity=24.1176470588235, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI34147522, Length=300, Percent_Identity=26, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI27363457, Length=305, Percent_Identity=24.5901639344262, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI217416386, Length=249, Percent_Identity=24.0963855421687, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI2367309, Length=478, Percent_Identity=30.1255230125523, Blast_Score=192, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17559152, Length=297, Percent_Identity=30.6397306397306, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI32565180, Length=262, Percent_Identity=26.7175572519084, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323282, Length=261, Percent_Identity=28.735632183908, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325148, Length=449, Percent_Identity=20.9354120267261, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=183, Percent_Identity=31.6939890710383, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24662575, Length=332, Percent_Identity=35.8433734939759, Blast_Score=176, Evalue=5e-44,
Organism=Drosophila melanogaster, GI22024280, Length=286, Percent_Identity=34.2657342657343, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI18859849, Length=283, Percent_Identity=28.6219081272085, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 65316; Mature: 65316

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASTLPSRAVLGSEPAKPYTAYRWARENYTRWGRLIDIWRFVLTWLFYLWLDQQAWSYG
CCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GQPTAERKAKRRRARAIWIRETLLHLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVP
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AFGYEQVAAIVQQELGKPIEQIYSYFDPTPLAAASLGQVHRAKLKTGEEVVVKVQRPGLT
CCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
RLFTIDLEICRGIAEFFQYHTRWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRN
EEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FRDMPQIAVPKVYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKLLARLGAEAYLRQL
HHCCCCHHCCHHEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHCHHHHHHHH
LKDGFFHADPHPGNIAVKPDGTLIFYDFGMMGRIRPGIKGKLVAMLAAVVAKNADLVVAS
HHCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSNSSDEISVMAISEDLYELAYDQPFRFP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCC
ATFTFVMRALTTLEGLGKSLDPEFNFLEVAKPFAEELMNGSKPETETLLAQVSRQAAEFT
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SSSLSLPRRLEATLSKLEQGELRLRVRSSEAERLLRKLNSTGRGVIYAVLFATFFLSATQ
HHHCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LFSAGHATLAIVTLALAVLAALALVRVLLKANGSEPLM
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNASTLPSRAVLGSEPAKPYTAYRWARENYTRWGRLIDIWRFVLTWLFYLWLDQQAWSYG
CCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GQPTAERKAKRRRARAIWIRETLLHLGPTFIKVGQFFSTRADLFPSEYVEELSKLQDRVP
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AFGYEQVAAIVQQELGKPIEQIYSYFDPTPLAAASLGQVHRAKLKTGEEVVVKVQRPGLT
CCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
RLFTIDLEICRGIAEFFQYHTRWGGPGRDWIGIYEECRRTLWEEVDYLNEGRNADTFRRN
EEEEEHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
FRDMPQIAVPKVYWRYTSPRLLTLEYLPGIKISDYEALSAAGLDRKLLARLGAEAYLRQL
HHCCCCHHCCHHEEEECCCCEEEEECCCCCCCCCCHHHHHCCCCHHHHHHHCHHHHHHHH
LKDGFFHADPHPGNIAVKPDGTLIFYDFGMMGRIRPGIKGKLVAMLAAVVAKNADLVVAS
HHCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LVELGVLVPTADLAPVRRSVQYMLDHFMDKPFSNSSDEISVMAISEDLYELAYDQPFRFP
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCC
ATFTFVMRALTTLEGLGKSLDPEFNFLEVAKPFAEELMNGSKPETETLLAQVSRQAAEFT
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
SSSLSLPRRLEATLSKLEQGELRLRVRSSEAERLLRKLNSTGRGVIYAVLFATFFLSATQ
HHHCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LFSAGHATLAIVTLALAVLAALALVRVLLKANGSEPLM
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]