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The map label for this gene is moaC

Identifier: 86604899

GI number: 86604899

Start: 167841

End: 168935

Strand: Reverse

Name: moaC

Synonym: CYA_0171

Alternate gene names: 86604899

Gene position: 168935-167841 (Counterclockwise)

Preceding gene: 86604900

Following gene: 86604898

Centisome position: 5.76

GC content: 52.24

Gene sequence:

>1095_bases
ATGGACAAAGCTGATCGTACATGGGCCCATCTTAATGCTCAAGGCCATCCGCATATGGTAGATATTAGCCACAAATCGGT
GTCTTTGCGAACGGCCACAGCACGGGCAAGAGTTCAACTGCCACCTGCTCTCAGATCCTATGTTGTTGGCCAAGATATCC
ACCTGAAAAAAGGACCGGTATTTCAGACAGCAACCATTGCCGGTACAATGGCTGTTAAAAGAACTGACCAACTGATCCCC
TTTTGTCATCAGATCCCTGTTGAAGACTGCACCTTTGATATCACAATTGATGATCACTTGCTTGTAACCATCCACTGCAC
TGTCAAGACCAGCGCTAAGACAGGGGTTGAAATGGAAGCTCTCTGTGGTGCGGCAACAGCAGCGCTGACAATCTATGACA
TGTGCAAGTCGGTGTCGCCCCATATCTGCATCCAGGAGACCCGCCTAGTAACTAAGTCCGGCGGCAAAAACGCCCTCCTG
GAACGTCCCCTCTATGGCTTGGTGCTCACAGGGGGACGTAGCAAGCGCATGGGTCGCGATAAAGCGCTGCTGAACCCTTT
TGGCAAACCCCACGCCGCCTATCTCTATGAACTGCTGCAGCCCTACTGCCAGCAGGTTTACTTGTCAGCGCGTGCCGGTC
AGTGGTCGGGCACAGCTCTAGAGCTCTTGCCCACACTACCAGATCTAGTAGAAAGCGTTGGCCCGATCAGTGGCCTATTG
ACTGCCTTGAATACTCATCCTGAAGCTAACTGGTTGGTTGTTGCCTGTGATCTACTGAACCTTCGGTCAGAAACAATCCA
AAAGCTGCTGGATCACTACCAAGCCGAAACAATCGCAACTTGCTATGTTAACCCCGAGCGCGGCTTCCCGGAAGCTCTTT
GCGCCATCTATACTCCTCAAGCTGCAGCGGTACTAGAAAGGGCTTACGCGGAAGGGGTGTACTGCCCTGTGGAAATCCTC
AGCAGGCAGCCCTGCACCCTAGTTACCCCCAACCATGAGGTCGAGCTCATGAACGTCAATACCGCCGAGGAGTATGCCAC
TTTCCAATCCGTTTGGGGTAGTTGCAGCCATGGTAACTCAATCTGTCCTAAGTAA

Upstream 100 bases:

>100_bases
GGCCAACGTCAGCAAATTTACCAGCAGCTTTTGGGGATGAAACCACTGCGCCGGGTTGAGCAGGTCTCACACCCAATGTA
CGGCTTAGGGGGCTAGCTCT

Downstream 100 bases:

>100_bases
GACCGTAACAATTCAATATGTAGCAGTGCTGCGGGAACAGGCTCAGCGGAGCAGCGAAGTGCTGCAAACCAGTGCAGCAA
ACTACCTAGAGCTCTATCAG

Product: bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MoaC/MobA

Products: NA

Alternate protein names: Molybdenum cofactor biosynthesis protein C; Molybdopterin-guanine dinucleotide biosynthesis protein A [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MDKADRTWAHLNAQGHPHMVDISHKSVSLRTATARARVQLPPALRSYVVGQDIHLKKGPVFQTATIAGTMAVKRTDQLIP
FCHQIPVEDCTFDITIDDHLLVTIHCTVKTSAKTGVEMEALCGAATAALTIYDMCKSVSPHICIQETRLVTKSGGKNALL
ERPLYGLVLTGGRSKRMGRDKALLNPFGKPHAAYLYELLQPYCQQVYLSARAGQWSGTALELLPTLPDLVESVGPISGLL
TALNTHPEANWLVVACDLLNLRSETIQKLLDHYQAETIATCYVNPERGFPEALCAIYTPQAAAVLERAYAEGVYCPVEIL
SRQPCTLVTPNHEVELMNVNTAEEYATFQSVWGSCSHGNSICPK

Sequences:

>Translated_364_residues
MDKADRTWAHLNAQGHPHMVDISHKSVSLRTATARARVQLPPALRSYVVGQDIHLKKGPVFQTATIAGTMAVKRTDQLIP
FCHQIPVEDCTFDITIDDHLLVTIHCTVKTSAKTGVEMEALCGAATAALTIYDMCKSVSPHICIQETRLVTKSGGKNALL
ERPLYGLVLTGGRSKRMGRDKALLNPFGKPHAAYLYELLQPYCQQVYLSARAGQWSGTALELLPTLPDLVESVGPISGLL
TALNTHPEANWLVVACDLLNLRSETIQKLLDHYQAETIATCYVNPERGFPEALCAIYTPQAAAVLERAYAEGVYCPVEIL
SRQPCTLVTPNHEVELMNVNTAEEYATFQSVWGSCSHGNSICPK
>Mature_364_residues
MDKADRTWAHLNAQGHPHMVDISHKSVSLRTATARARVQLPPALRSYVVGQDIHLKKGPVFQTATIAGTMAVKRTDQLIP
FCHQIPVEDCTFDITIDDHLLVTIHCTVKTSAKTGVEMEALCGAATAALTIYDMCKSVSPHICIQETRLVTKSGGKNALL
ERPLYGLVLTGGRSKRMGRDKALLNPFGKPHAAYLYELLQPYCQQVYLSARAGQWSGTALELLPTLPDLVESVGPISGLL
TALNTHPEANWLVVACDLLNLRSETIQKLLDHYQAETIATCYVNPERGFPEALCAIYTPQAAAVLERAYAEGVYCPVEIL
SRQPCTLVTPNHEVELMNVNTAEEYATFQSVWGSCSHGNSICPK

Specific function: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD) [H]

COG id: COG0746

COG function: function code H; Molybdopterin-guanine dinucleotide biosynthesis protein A

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the mobA family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=149, Percent_Identity=44.2953020134228, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=39.7350993377483, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28574490, Length=161, Percent_Identity=43.4782608695652, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI28574492, Length=152, Percent_Identity=44.078947368421, Blast_Score=114, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR002820
- InterPro:   IPR013482 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 39862; Mature: 39862

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKADRTWAHLNAQGHPHMVDISHKSVSLRTATARARVQLPPALRSYVVGQDIHLKKGPV
CCCCCCCEEEECCCCCCEEEEECCCEEEEEEECCEEEEECCHHHHHHHCCCCEEECCCCC
FQTATIAGTMAVKRTDQLIPFCHQIPVEDCTFDITIDDHLLVTIHCTVKTSAKTGVEMEA
EEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEEEEEECCCCCCCHHH
LCGAATAALTIYDMCKSVSPHICIQETRLVTKSGGKNALLERPLYGLVLTGGRSKRMGRD
HHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCHHCCCCEEEEEECCCCCCCCCC
KALLNPFGKPHAAYLYELLQPYCQQVYLSARAGQWSGTALELLPTLPDLVESVGPISGLL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHCHHHHHH
TALNTHPEANWLVVACDLLNLRSETIQKLLDHYQAETIATCYVNPERGFPEALCAIYTPQ
HHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCH
AAAVLERAYAEGVYCPVEILSRQPCTLVTPNHEVELMNVNTAEEYATFQSVWGSCSHGNS
HHHHHHHHHHCCCCCHHHHHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCC
ICPK
CCCC
>Mature Secondary Structure
MDKADRTWAHLNAQGHPHMVDISHKSVSLRTATARARVQLPPALRSYVVGQDIHLKKGPV
CCCCCCCEEEECCCCCCEEEEECCCEEEEEEECCEEEEECCHHHHHHHCCCCEEECCCCC
FQTATIAGTMAVKRTDQLIPFCHQIPVEDCTFDITIDDHLLVTIHCTVKTSAKTGVEMEA
EEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEEEEEECCCCCCCHHH
LCGAATAALTIYDMCKSVSPHICIQETRLVTKSGGKNALLERPLYGLVLTGGRSKRMGRD
HHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCHHCCCCEEEEEECCCCCCCCCC
KALLNPFGKPHAAYLYELLQPYCQQVYLSARAGQWSGTALELLPTLPDLVESVGPISGLL
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHCHHHHHH
TALNTHPEANWLVVACDLLNLRSETIQKLLDHYQAETIATCYVNPERGFPEALCAIYTPQ
HHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHCCCH
AAAVLERAYAEGVYCPVEILSRQPCTLVTPNHEVELMNVNTAEEYATFQSVWGSCSHGNS
HHHHHHHHHHCCCCCHHHHHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCC
ICPK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]