Click here to switch to the map view.

The map label for this gene is fixNf

Identifier: 86361236

GI number: 86361236

Start: 570563

End: 571915

Strand: Reverse

Name: fixNf

Synonym: RHE_PF00507

Alternate gene names: 86361236

Gene position: 571915-570563 (Counterclockwise)

Preceding gene: 86361242

Following gene: 86361235

Centisome position: 89.01

GC content: 60.24

Gene sequence:

>1353_bases
GTGATTATCGCGCTGCAACTGGCCTTTCCCGACCTCAACATTGCGCCCTATCTCAACTTCGGACGATTGCGGCCGGTTCA
CACCTCAGCTGTCATCTTCGCCTTCGGCGGCAACGCGCTGATCATGACCTCGTTCTACGTGGTGCAGCGCACCTGTCGCG
CGCGTCTCTTCGGCGGCACGCTCGCCTGGTTCGTCTTCTGGGGCTACCAGCTCTTCATCGTCATGGCTGCGACTGGCTAC
GTGCTCGGCATCACCCAGGCCCGTGAATATGCCGAGCCCGAGTGGTATGTCGATCTGTGGCTGACTATCGTCTGGGTCGC
CTATCTCGCCGTCTATCTCGGAACAATCCTGAAGCGCAAGGAACCGCATATCTATGTGGCGAACTGGTTCTATCTCGGCT
TCATCGTCACCATTGCGATGCTGCATGTGGTCAACAATCTTGCGGTTCCGGCCTCGTTCCTGGGCTCCAAGAGCTATTCG
CTCTTCTCCGGCGTTCAGGATGCGCTGACCCAATGGTGGTATGGCCATAATGCCGTCGGCTTCTTCCTCACCGCCGGCTT
CCTCGGCATGATGTACTATTTCGTGCCGAAGCAGGCCAACCGGCCCGTCTATTCCTACCGGCTGTCGATCATCCACTTCT
GGGCTCTGATCTTCATGTATATCTGGGCCGGTCCGCACCACCTGCATTACACGGCGCTGCCCGACTGGGCGCAGACGCTC
GGCATGGTGTTCTCGGTCATGCTCTGGATGCCCTCCTGGGGCGGCATGATCAACGGCCTGATGACCCTTTCGGGCGCCTG
GGACAAGATCCGCACGGACCCGATCATCCGCATGATGATCGTCGCCATCGCCTTTTACGGCATGTCGACTTTCGAAGGCC
CGATGATGTCGGTCAAAACAGTCAATTCGCTCAGCCACTATACCGAATGGACGATCGGCCACGTGCATTCCGGGGCGCTC
GGCTGGGTGGGTATGATCACCTTCGGGGCGATCTATTACCTGACGCCGAAGCTGTGGGGGCGCGAGCGTCTCTATAGCCT
GCGGATGGTCAACTGGCACTTCTGGCTCGCGACCCTCGGAATCGTGATCTACGCCGCTGTGCTCTGGGTTGCCGGCATCC
AGCAGGGGCTGATGTGGCGCGAATACAATTCCCAGGGCTTCCTCGTCTATTCCTTCGCGGAGACGGTCGCGGCGATGATC
CCCTACTACGTGCTGCGCGCGGTCGGCGGAGCGCTTTACCTGGCGGGCGGTCTCGTCATGGCCTGGAACGTGTTCATGAC
GATCCGCGGCCACCTGCGCGACGAAGCTGCTATCCCGACCACTTTCGTGCCCCAGGCACAGCCTGCCGAATGA

Upstream 100 bases:

>100_bases
GGCCAACAGCGCAAGGCCGACGTAACAGGTTATTTCGACGAGGTGGTCCGCTACGGCCTGATCGCCACGGTTCTGGGGCG
TCGTCGGCTTCCTCGTCGGC

Downstream 100 bases:

>100_bases
GGTGAGACATGGCATCGATACTTGATAAACATAAGATCCTCGAGAAGAACGCGACGCTTCTTCTGGTCGGCTCGCTGCTC
GTCGTCAGCATCGGCGGCAT

Product: cytochrome C oxidase, fixN chain protein

Products: NA

Alternate protein names: Cytochrome c oxidase polypeptide I homolog [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MIIALQLAFPDLNIAPYLNFGRLRPVHTSAVIFAFGGNALIMTSFYVVQRTCRARLFGGTLAWFVFWGYQLFIVMAATGY
VLGITQAREYAEPEWYVDLWLTIVWVAYLAVYLGTILKRKEPHIYVANWFYLGFIVTIAMLHVVNNLAVPASFLGSKSYS
LFSGVQDALTQWWYGHNAVGFFLTAGFLGMMYYFVPKQANRPVYSYRLSIIHFWALIFMYIWAGPHHLHYTALPDWAQTL
GMVFSVMLWMPSWGGMINGLMTLSGAWDKIRTDPIIRMMIVAIAFYGMSTFEGPMMSVKTVNSLSHYTEWTIGHVHSGAL
GWVGMITFGAIYYLTPKLWGRERLYSLRMVNWHFWLATLGIVIYAAVLWVAGIQQGLMWREYNSQGFLVYSFAETVAAMI
PYYVLRAVGGALYLAGGLVMAWNVFMTIRGHLRDEAAIPTTFVPQAQPAE

Sequences:

>Translated_450_residues
MIIALQLAFPDLNIAPYLNFGRLRPVHTSAVIFAFGGNALIMTSFYVVQRTCRARLFGGTLAWFVFWGYQLFIVMAATGY
VLGITQAREYAEPEWYVDLWLTIVWVAYLAVYLGTILKRKEPHIYVANWFYLGFIVTIAMLHVVNNLAVPASFLGSKSYS
LFSGVQDALTQWWYGHNAVGFFLTAGFLGMMYYFVPKQANRPVYSYRLSIIHFWALIFMYIWAGPHHLHYTALPDWAQTL
GMVFSVMLWMPSWGGMINGLMTLSGAWDKIRTDPIIRMMIVAIAFYGMSTFEGPMMSVKTVNSLSHYTEWTIGHVHSGAL
GWVGMITFGAIYYLTPKLWGRERLYSLRMVNWHFWLATLGIVIYAAVLWVAGIQQGLMWREYNSQGFLVYSFAETVAAMI
PYYVLRAVGGALYLAGGLVMAWNVFMTIRGHLRDEAAIPTTFVPQAQPAE
>Mature_450_residues
MIIALQLAFPDLNIAPYLNFGRLRPVHTSAVIFAFGGNALIMTSFYVVQRTCRARLFGGTLAWFVFWGYQLFIVMAATGY
VLGITQAREYAEPEWYVDLWLTIVWVAYLAVYLGTILKRKEPHIYVANWFYLGFIVTIAMLHVVNNLAVPASFLGSKSYS
LFSGVQDALTQWWYGHNAVGFFLTAGFLGMMYYFVPKQANRPVYSYRLSIIHFWALIFMYIWAGPHHLHYTALPDWAQTL
GMVFSVMLWMPSWGGMINGLMTLSGAWDKIRTDPIIRMMIVAIAFYGMSTFEGPMMSVKTVNSLSHYTEWTIGHVHSGAL
GWVGMITFGAIYYLTPKLWGRERLYSLRMVNWHFWLATLGIVIYAAVLWVAGIQQGLMWREYNSQGFLVYSFAETVAAMI
PYYVLRAVGGALYLAGGLVMAWNVFMTIRGHLRDEAAIPTTFVPQAQPAE

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 51162; Mature: 51162

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIALQLAFPDLNIAPYLNFGRLRPVHTSAVIFAFGGNALIMTSFYVVQRTCRARLFGGT
CEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCHH
LAWFVFWGYQLFIVMAATGYVLGITQAREYAEPEWYVDLWLTIVWVAYLAVYLGTILKRK
HHHHHHHHHHHHHHHHHHCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EPHIYVANWFYLGFIVTIAMLHVVNNLAVPASFLGSKSYSLFSGVQDALTQWWYGHNAVG
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHH
FFLTAGFLGMMYYFVPKQANRPVYSYRLSIIHFWALIFMYIWAGPHHLHYTALPDWAQTL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
GMVFSVMLWMPSWGGMINGLMTLSGAWDKIRTDPIIRMMIVAIAFYGMSTFEGPMMSVKT
HHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
VNSLSHYTEWTIGHVHSGALGWVGMITFGAIYYLTPKLWGRERLYSLRMVNWHFWLATLG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IVIYAAVLWVAGIQQGLMWREYNSQGFLVYSFAETVAAMIPYYVLRAVGGALYLAGGLVM
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWNVFMTIRGHLRDEAAIPTTFVPQAQPAE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIALQLAFPDLNIAPYLNFGRLRPVHTSAVIFAFGGNALIMTSFYVVQRTCRARLFGGT
CEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCHH
LAWFVFWGYQLFIVMAATGYVLGITQAREYAEPEWYVDLWLTIVWVAYLAVYLGTILKRK
HHHHHHHHHHHHHHHHHHCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
EPHIYVANWFYLGFIVTIAMLHVVNNLAVPASFLGSKSYSLFSGVQDALTQWWYGHNAVG
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHCCCCHHH
FFLTAGFLGMMYYFVPKQANRPVYSYRLSIIHFWALIFMYIWAGPHHLHYTALPDWAQTL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHH
GMVFSVMLWMPSWGGMINGLMTLSGAWDKIRTDPIIRMMIVAIAFYGMSTFEGPMMSVKT
HHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
VNSLSHYTEWTIGHVHSGALGWVGMITFGAIYYLTPKLWGRERLYSLRMVNWHFWLATLG
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
IVIYAAVLWVAGIQQGLMWREYNSQGFLVYSFAETVAAMIPYYVLRAVGGALYLAGGLVM
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AWNVFMTIRGHLRDEAAIPTTFVPQAQPAE
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7753030 [H]