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The map label for this gene is yafC [H]

Identifier: 86361206

GI number: 86361206

Start: 537520

End: 538443

Strand: Direct

Name: yafC [H]

Synonym: RHE_PF00476

Alternate gene names: 86361206

Gene position: 537520-538443 (Clockwise)

Preceding gene: 86361204

Following gene: 86361208

Centisome position: 83.66

GC content: 63.2

Gene sequence:

>924_bases
ATGGATAGTCTCGCGAGCCTCTTCGCCTTCGTTCATGCGGCCGAACAGCAGAGTTATGTCGCAGCCGCGCGCATTGCCGG
CGTTTCGCCATCCGCGATCGGCAAGGCAGTGGCGCGTCTTGAACGCCGGCTCCGTGTGCGGCTCTTCAACCGCACGACCC
GCAGCATCAGCCTGACCGAGGAAGGGGCTGTCCTTTACGAGCGCTACAAGCGCATCATCGACGATATGCAGGACGCGGAG
GCAACCGTCCTGCAAAGCCGGGAACGCCCAAGGGGCCGCCTGCGCGTCAGCGTTCCGCACATCGTCGGACACCATCTGCT
GATGCCGATGCTGCCGGCCTTTGCCGAGCGCTTCCCGGAAATCGAGCTGGATGTGGATTTCGAAGACAGGGTCATAGACC
TCGTTGCGGAAGGTCTGGATGTCGTGGTGCGCAGTGGCGAACTGGCCGATGCGCGGCTGATCGCCCGCCATCTCGGCGAT
CAACATTTCGTCGTCTGCGGCAGTCCAGATTATTTCGAGCGCCATGGACAACCGGAGACGCCTGACGATCTCTCCAGGCA
CGCCTGCATTCGCTTCAAATATCCATCCAGCGGCCGCGTCGCGCCCTGGGCCCTCCGCGCGCCGTACGAGCGGCTGCTTC
TGCCGAGAAGCCTGACGTTCAACAATACGGATGCAGGGCTGCGGGCAGCACAGGGTGGTTTGGGTCTCGCCCATCTGCCC
GTCTATGTCGCGCAGCCAGCCATGCGGGCCGGAACTCTGATCCCCGTCCTCACCTCCTTCATGGTGCCCTTTGGCTCGCT
CTCGCTGGTCTGGCCATCCAATCGCCAGCTTTCGCCGAAAGTCCGCGCTTTCGTGGATTTCGTCGTCGGGAATTGTGCCG
CACGAGCCGACGCTTTTCGATCGGCAGCCAGCCTGTCGCGCTGA

Upstream 100 bases:

>100_bases
CGTTCCGGCTGCCTAACAAAGGATATTTGTTATGCAATGTTGATCAATCACCGGGTATGGACATACATAAAGGACAAAAT
GTCTCCAATAAGATCTTGCC

Downstream 100 bases:

>100_bases
TCCGCTGTCGCGCCATACCCGAAGTGGGTACACTTTCCATACTCACAACGCTGGGAGCTTTGATGCTCAGCCGCAGTTCC
GGCTTGGTCTTGGATCGGAA

Product: transcriptional regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDSLASLFAFVHAAEQQSYVAAARIAGVSPSAIGKAVARLERRLRVRLFNRTTRSISLTEEGAVLYERYKRIIDDMQDAE
ATVLQSRERPRGRLRVSVPHIVGHHLLMPMLPAFAERFPEIELDVDFEDRVIDLVAEGLDVVVRSGELADARLIARHLGD
QHFVVCGSPDYFERHGQPETPDDLSRHACIRFKYPSSGRVAPWALRAPYERLLLPRSLTFNNTDAGLRAAQGGLGLAHLP
VYVAQPAMRAGTLIPVLTSFMVPFGSLSLVWPSNRQLSPKVRAFVDFVVGNCAARADAFRSAASLSR

Sequences:

>Translated_307_residues
MDSLASLFAFVHAAEQQSYVAAARIAGVSPSAIGKAVARLERRLRVRLFNRTTRSISLTEEGAVLYERYKRIIDDMQDAE
ATVLQSRERPRGRLRVSVPHIVGHHLLMPMLPAFAERFPEIELDVDFEDRVIDLVAEGLDVVVRSGELADARLIARHLGD
QHFVVCGSPDYFERHGQPETPDDLSRHACIRFKYPSSGRVAPWALRAPYERLLLPRSLTFNNTDAGLRAAQGGLGLAHLP
VYVAQPAMRAGTLIPVLTSFMVPFGSLSLVWPSNRQLSPKVRAFVDFVVGNCAARADAFRSAASLSR
>Mature_307_residues
MDSLASLFAFVHAAEQQSYVAAARIAGVSPSAIGKAVARLERRLRVRLFNRTTRSISLTEEGAVLYERYKRIIDDMQDAE
ATVLQSRERPRGRLRVSVPHIVGHHLLMPMLPAFAERFPEIELDVDFEDRVIDLVAEGLDVVVRSGELADARLIARHLGD
QHFVVCGSPDYFERHGQPETPDDLSRHACIRFKYPSSGRVAPWALRAPYERLLLPRSLTFNNTDAGLRAAQGGLGLAHLP
VYVAQPAMRAGTLIPVLTSFMVPFGSLSLVWPSNRQLSPKVRAFVDFVVGNCAARADAFRSAASLSR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=36.0424028268551, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=34.3537414965986, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1787128, Length=289, Percent_Identity=32.5259515570934, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=32.6388888888889, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789639, Length=241, Percent_Identity=31.1203319502075, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87081978, Length=288, Percent_Identity=32.2916666666667, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789440, Length=304, Percent_Identity=27.6315789473684, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788706, Length=296, Percent_Identity=25.6756756756757, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789173, Length=303, Percent_Identity=27.7227722772277, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786448, Length=289, Percent_Identity=26.643598615917, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790011, Length=278, Percent_Identity=22.3021582733813, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33994; Mature: 33994

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLASLFAFVHAAEQQSYVAAARIAGVSPSAIGKAVARLERRLRVRLFNRTTRSISLTE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
EGAVLYERYKRIIDDMQDAEATVLQSRERPRGRLRVSVPHIVGHHLLMPMLPAFAERFPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
IELDVDFEDRVIDLVAEGLDVVVRSGELADARLIARHLGDQHFVVCGSPDYFERHGQPET
EEEECCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCC
PDDLSRHACIRFKYPSSGRVAPWALRAPYERLLLPRSLTFNNTDAGLRAAQGGLGLAHLP
HHHHCCCEEEEEECCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHH
VYVAQPAMRAGTLIPVLTSFMVPFGSLSLVWPSNRQLSPKVRAFVDFVVGNCAARADAFR
HHHHCCHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASLSR
HHHHCCC
>Mature Secondary Structure
MDSLASLFAFVHAAEQQSYVAAARIAGVSPSAIGKAVARLERRLRVRLFNRTTRSISLTE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
EGAVLYERYKRIIDDMQDAEATVLQSRERPRGRLRVSVPHIVGHHLLMPMLPAFAERFPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCC
IELDVDFEDRVIDLVAEGLDVVVRSGELADARLIARHLGDQHFVVCGSPDYFERHGQPET
EEEECCHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHCCCCEEEEECCCHHHHHCCCCCC
PDDLSRHACIRFKYPSSGRVAPWALRAPYERLLLPRSLTFNNTDAGLRAAQGGLGLAHLP
HHHHCCCEEEEEECCCCCCCCCCHHHCCHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHH
VYVAQPAMRAGTLIPVLTSFMVPFGSLSLVWPSNRQLSPKVRAFVDFVVGNCAARADAFR
HHHHCCHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAASLSR
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]