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The map label for this gene is dapAf3

Identifier: 86361128

GI number: 86361128

Start: 451279

End: 452190

Strand: Reverse

Name: dapAf3

Synonym: RHE_PF00398

Alternate gene names: 86361128

Gene position: 452190-451279 (Counterclockwise)

Preceding gene: 86361129

Following gene: 86361127

Centisome position: 70.38

GC content: 61.62

Gene sequence:

>912_bases
GTGAAGTTTGAGGGGATCTACACGCCGGCGGTAACGCCGCTCGATCGAAATGGTCAGATCGACCGGGCCGGTTTCGCCGC
TGTGCTGGAGTCGCTGATCGAGGCGGGCGTCCACGGCATTATCGTCGGCGGCTCGACGGGTGAATATTACGCCCAGAGCA
GCCAGGAGCGTTTCGAACTCGCGGCCCATGCCAAAGAGGTCATCGGCACGCGGCTGCCGCTTATCATCGGCACCGGCGCC
ACGCGCACCGAGGATTCGGTCGAATATGCGAAGGCTGCAAAGGAAATCGGCGCGGATGCGATCCTGGTTTCGTCGCCGCC
CTATGCACTGCCGACCGAACGCGAGAATGCAGTCCATACCCTGACTGTCGATCGCGCCGCCAACCTGCCGATCATGCTTT
ACAACTATCCGGCCCGCATGGGTGTGGTGATGGGCGAGGAGTATTTCTCCCGCGTCGGCAAGTCGAAGAACGTCGTCGCC
ATCAAGGAAAGCTCCGGCGACATGGGTAATCTGCATCTGCTCGCCCGGAAGTTTCCGCATATTTCGCTGTCCTGCGGCTG
GGACGACCAGGCGCTCGAATTCTTCGCCTGGGGTGCGAAGAGTTGGGTTTGCGCCGGCTCCAACTTCCTGCCGCGCGAGC
ATGTTGCCCTCTATGAAGCCTGCGTCGTCGAGAAGAATTTCGACAAGGGCCGGGCGATCATGAGCGCCATGCTGCCGCTG
ATGGATTTCCTGGAATGCGGCAAGTTCGTCCAGTCGATCAAGCACGGATGCGAGATCATCGGCCTCAAGGCCGGCCCCGT
GCGGGCGCCGCTGCGCGGACTGAACTCCGAAGAGAAAAGAACCCTTGAGACCGTCGTTGCCTCGCTGAAGCGCACGGTCG
GCCAGATCACGTCGGGAGCCAACCATGCATGA

Upstream 100 bases:

>100_bases
AATTGTCCCGCGAGAACATGGAGATGTTCATCGCACCGCAAGGCCTTAAGGCGGACGCCTTCGTCGGCGGTCCAGCCACG
CACATATTGGAGAAGTCATC

Downstream 100 bases:

>100_bases
ACCTTTGACCGCAGCCGAATACAAGGCGATTGCCGCCGGTCTTCAACTTCCGACGAATGCCTTCATCGATGGCGCATTCC
GTCCGGCAAATTCCGGCAAG

Product: dihydrodipicolinate synthase protein

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKFEGIYTPAVTPLDRNGQIDRAGFAAVLESLIEAGVHGIIVGGSTGEYYAQSSQERFELAAHAKEVIGTRLPLIIGTGA
TRTEDSVEYAKAAKEIGADAILVSSPPYALPTERENAVHTLTVDRAANLPIMLYNYPARMGVVMGEEYFSRVGKSKNVVA
IKESSGDMGNLHLLARKFPHISLSCGWDDQALEFFAWGAKSWVCAGSNFLPREHVALYEACVVEKNFDKGRAIMSAMLPL
MDFLECGKFVQSIKHGCEIIGLKAGPVRAPLRGLNSEEKRTLETVVASLKRTVGQITSGANHA

Sequences:

>Translated_303_residues
MKFEGIYTPAVTPLDRNGQIDRAGFAAVLESLIEAGVHGIIVGGSTGEYYAQSSQERFELAAHAKEVIGTRLPLIIGTGA
TRTEDSVEYAKAAKEIGADAILVSSPPYALPTERENAVHTLTVDRAANLPIMLYNYPARMGVVMGEEYFSRVGKSKNVVA
IKESSGDMGNLHLLARKFPHISLSCGWDDQALEFFAWGAKSWVCAGSNFLPREHVALYEACVVEKNFDKGRAIMSAMLPL
MDFLECGKFVQSIKHGCEIIGLKAGPVRAPLRGLNSEEKRTLETVVASLKRTVGQITSGANHA
>Mature_303_residues
MKFEGIYTPAVTPLDRNGQIDRAGFAAVLESLIEAGVHGIIVGGSTGEYYAQSSQERFELAAHAKEVIGTRLPLIIGTGA
TRTEDSVEYAKAAKEIGADAILVSSPPYALPTERENAVHTLTVDRAANLPIMLYNYPARMGVVMGEEYFSRVGKSKNVVA
IKESSGDMGNLHLLARKFPHISLSCGWDDQALEFFAWGAKSWVCAGSNFLPREHVALYEACVVEKNFDKGRAIMSAMLPL
MDFLECGKFVQSIKHGCEIIGLKAGPVRAPLRGLNSEEKRTLETVVASLKRTVGQITSGANHA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=287, Percent_Identity=26.4808362369338, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI13540533, Length=298, Percent_Identity=27.5167785234899, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1786463, Length=223, Percent_Identity=32.2869955156951, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87082415, Length=268, Percent_Identity=29.4776119402985, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788823, Length=293, Percent_Identity=26.6211604095563, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789620, Length=197, Percent_Identity=30.9644670050761, Blast_Score=98, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 32800; Mature: 32800

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFEGIYTPAVTPLDRNGQIDRAGFAAVLESLIEAGVHGIIVGGSTGEYYAQSSQERFEL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHH
AAHAKEVIGTRLPLIIGTGATRTEDSVEYAKAAKEIGADAILVSSPPYALPTERENAVHT
HHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEE
LTVDRAANLPIMLYNYPARMGVVMGEEYFSRVGKSKNVVAIKESSGDMGNLHLLARKFPH
EEECCCCCCCEEEEECCCHHHHEECHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCC
ISLSCGWDDQALEFFAWGAKSWVCAGSNFLPREHVALYEACVVEKNFDKGRAIMSAMLPL
EEEECCCCHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MDFLECGKFVQSIKHGCEIIGLKAGPVRAPLRGLNSEEKRTLETVVASLKRTVGQITSGA
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NHA
CCC
>Mature Secondary Structure
MKFEGIYTPAVTPLDRNGQIDRAGFAAVLESLIEAGVHGIIVGGSTGEYYAQSSQERFEL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHHHHH
AAHAKEVIGTRLPLIIGTGATRTEDSVEYAKAAKEIGADAILVSSPPYALPTERENAVHT
HHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEE
LTVDRAANLPIMLYNYPARMGVVMGEEYFSRVGKSKNVVAIKESSGDMGNLHLLARKFPH
EEECCCCCCCEEEEECCCHHHHEECHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCC
ISLSCGWDDQALEFFAWGAKSWVCAGSNFLPREHVALYEACVVEKNFDKGRAIMSAMLPL
EEEECCCCHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MDFLECGKFVQSIKHGCEIIGLKAGPVRAPLRGLNSEEKRTLETVVASLKRTVGQITSGA
HHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC
NHA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA