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The map label for this gene is pepE [H]

Identifier: 86361099

GI number: 86361099

Start: 416971

End: 418161

Strand: Reverse

Name: pepE [H]

Synonym: RHE_PF00369

Alternate gene names: 86361099

Gene position: 418161-416971 (Counterclockwise)

Preceding gene: 86361100

Following gene: 86361096

Centisome position: 65.08

GC content: 61.38

Gene sequence:

>1191_bases
ATGAACGACAATGCAGGGCAAGCAAGGCAGCCCACTGTGGCGCCGTTCGATACGGCCAAGCTCGACCGCCTCATGGAGGA
AGCCGGTATCGACGTCATCGCCGCCACTTCAAAACACAACACGCAATATCTCATGGGCGGCTACAAGTTCATCTTCTTCG
CCGCCATGGATGCGATCGGGCATAGCCGGTACCTGCCGATGGTAATTTACGAGAAAGGCGCGCCTGATCACTCCGCCTAT
GTGGGAAACCGCATGGAAGGCGCAGAGCACCAGAACAATCCATTCTGGACGCCCGCAGTGCATACGGCGACCTGGGGCAC
GCAGGACGCAGCCGGGCTCGCCGTCGAGCACCTGAAGAAAATCGGCAAGGCGAGTGGGCGGATCGGCATCGAGCCAGCCT
TCCTGCCATCCGACGCCCGCGATCTTCTTGCCTCTCGGCTGGATGGCGCTCGATTTGTCGATGCCACGCATGTTTTGGAG
CGGCTGAGGGCCGTCAAGACAGCGGACGAACTGGCAAAGCTCAGACGCGCCTCCGAACTGATCACCGACTCGATGCTGGC
GACGATCGCGGCGGCCCGCGCCGGCTCGACGAAACTGGAGATCATCGAGCAGCTGCGCCGGGAGGAGACGAACCGCGGGC
TGCACTTCGAATATTGTCTGCTGACGCTCGGCGCCAGTCACAACCGCGCGGGCTCGCCGCAGGCCTGGGCCGAGGGCGAG
ATCCTGTCAATCGATTCAGGCGGCAACTATCACGGATATATCGGTGACCTCTGCCGCATGGGCGTGCTCGGTGAACCGGA
TGCGGAGCTGGAGGACCTTCTGGCTGAAGTCGAACGTATCCAGCAAGCGGCCTTCGCCAAAGTCAGAGCAGGGGTTCTTG
GCAGTGAAATGATCGTCGCGGCGGAAGCCGAGCTCAAGGCCTCGCCATCGGCGGCCTTCACCGACTTCTTCTGCCATGGT
ATGGGCCTCATCACCCACGAAGCGCCGTTCCTCATGACGAATCACCCCGTCGCTTATGAGGGAATCGATGCCGACAAGCC
GCTGGAAGCCGGCAATGTCATTTCGGTCGAGACGACGATGCTTCACCCGAAGCGTGGTTTCATCAAGCTGGAGGATACGC
TGGCGATCACCGACAAGGGATATGAAATGTTCGGCGACCGTGGACGCGGCTGGAACCGCGGCGGAGTGTGA

Upstream 100 bases:

>100_bases
TCACCGGTGGGGCCGGAGCTTGCGCTTCGCGATTTGCCGGACTTCCGCCTGCTGCCGCAGGGCCTCTGAGGCGGACATCC
ATATCCTGGGAGGAAAGACA

Downstream 100 bases:

>100_bases
TTGCGCTCCGAGAGCCCTCAATGAAAGGCCCGGCAGATGTCACTGCCCGGCCTTTCGGTTTCTTGGTGCGGTGGTCTCAA
GTGTGGCGGATCTCCGTTCC

Product: proline M24 family dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MNDNAGQARQPTVAPFDTAKLDRLMEEAGIDVIAATSKHNTQYLMGGYKFIFFAAMDAIGHSRYLPMVIYEKGAPDHSAY
VGNRMEGAEHQNNPFWTPAVHTATWGTQDAAGLAVEHLKKIGKASGRIGIEPAFLPSDARDLLASRLDGARFVDATHVLE
RLRAVKTADELAKLRRASELITDSMLATIAAARAGSTKLEIIEQLRREETNRGLHFEYCLLTLGASHNRAGSPQAWAEGE
ILSIDSGGNYHGYIGDLCRMGVLGEPDAELEDLLAEVERIQQAAFAKVRAGVLGSEMIVAAEAELKASPSAAFTDFFCHG
MGLITHEAPFLMTNHPVAYEGIDADKPLEAGNVISVETTMLHPKRGFIKLEDTLAITDKGYEMFGDRGRGWNRGGV

Sequences:

>Translated_396_residues
MNDNAGQARQPTVAPFDTAKLDRLMEEAGIDVIAATSKHNTQYLMGGYKFIFFAAMDAIGHSRYLPMVIYEKGAPDHSAY
VGNRMEGAEHQNNPFWTPAVHTATWGTQDAAGLAVEHLKKIGKASGRIGIEPAFLPSDARDLLASRLDGARFVDATHVLE
RLRAVKTADELAKLRRASELITDSMLATIAAARAGSTKLEIIEQLRREETNRGLHFEYCLLTLGASHNRAGSPQAWAEGE
ILSIDSGGNYHGYIGDLCRMGVLGEPDAELEDLLAEVERIQQAAFAKVRAGVLGSEMIVAAEAELKASPSAAFTDFFCHG
MGLITHEAPFLMTNHPVAYEGIDADKPLEAGNVISVETTMLHPKRGFIKLEDTLAITDKGYEMFGDRGRGWNRGGV
>Mature_396_residues
MNDNAGQARQPTVAPFDTAKLDRLMEEAGIDVIAATSKHNTQYLMGGYKFIFFAAMDAIGHSRYLPMVIYEKGAPDHSAY
VGNRMEGAEHQNNPFWTPAVHTATWGTQDAAGLAVEHLKKIGKASGRIGIEPAFLPSDARDLLASRLDGARFVDATHVLE
RLRAVKTADELAKLRRASELITDSMLATIAAARAGSTKLEIIEQLRREETNRGLHFEYCLLTLGASHNRAGSPQAWAEGE
ILSIDSGGNYHGYIGDLCRMGVLGEPDAELEDLLAEVERIQQAAFAKVRAGVLGSEMIVAAEAELKASPSAAFTDFFCHG
MGLITHEAPFLMTNHPVAYEGIDADKPLEAGNVISVETTMLHPKRGFIKLEDTLAITDKGYEMFGDRGRGWNRGGV

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 43024; Mature: 43024

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNAGQARQPTVAPFDTAKLDRLMEEAGIDVIAATSKHNTQYLMGGYKFIFFAAMDAIG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHC
HSRYLPMVIYEKGAPDHSAYVGNRMEGAEHQNNPFWTPAVHTATWGTQDAAGLAVEHLKK
CCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
IGKASGRIGIEPAFLPSDARDLLASRLDGARFVDATHVLERLRAVKTADELAKLRRASEL
HHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITDSMLATIAAARAGSTKLEIIEQLRREETNRGLHFEYCLLTLGASHNRAGSPQAWAEGE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCC
ILSIDSGGNYHGYIGDLCRMGVLGEPDAELEDLLAEVERIQQAAFAKVRAGVLGSEMIVA
EEEECCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AEAELKASPSAAFTDFFCHGMGLITHEAPFLMTNHPVAYEGIDADKPLEAGNVISVETTM
ECCHHCCCCCHHHHHHHHHCCCCEECCCCEEEECCCCEECCCCCCCCCCCCCEEEEEEEE
LHPKRGFIKLEDTLAITDKGYEMFGDRGRGWNRGGV
ECCCCCCEEEECEEEEECCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNDNAGQARQPTVAPFDTAKLDRLMEEAGIDVIAATSKHNTQYLMGGYKFIFFAAMDAIG
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCEEECCCHHHHHHHHHHHHC
HSRYLPMVIYEKGAPDHSAYVGNRMEGAEHQNNPFWTPAVHTATWGTQDAAGLAVEHLKK
CCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHH
IGKASGRIGIEPAFLPSDARDLLASRLDGARFVDATHVLERLRAVKTADELAKLRRASEL
HHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITDSMLATIAAARAGSTKLEIIEQLRREETNRGLHFEYCLLTLGASHNRAGSPQAWAEGE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCCCCCC
ILSIDSGGNYHGYIGDLCRMGVLGEPDAELEDLLAEVERIQQAAFAKVRAGVLGSEMIVA
EEEECCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
AEAELKASPSAAFTDFFCHGMGLITHEAPFLMTNHPVAYEGIDADKPLEAGNVISVETTM
ECCHHCCCCCHHHHHHHHHCCCCEECCCCEEEECCCCEECCCCCCCCCCCCCEEEEEEEE
LHPKRGFIKLEDTLAITDKGYEMFGDRGRGWNRGGV
ECCCCCCEEEECEEEEECCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]