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The map label for this gene is apbE [H]

Identifier: 85860859

GI number: 85860859

Start: 3020737

End: 3021759

Strand: Direct

Name: apbE [H]

Synonym: SYN_01668

Alternate gene names: 85860859

Gene position: 3020737-3021759 (Clockwise)

Preceding gene: 85860858

Following gene: 85860860

Centisome position: 95.01

GC content: 54.84

Gene sequence:

>1023_bases
ATGAGATCCATGACAAAAACGACACAAAAAATGATCTTCGGTATTATTCTTACTGGATCGATGCTGGGCTTTTTCTGGAT
GGCATGGAGCCGAATCGCGAATGAACCGCTGGTTCGTTCACGGCTGATGATGGGGACGATTATCGAAATAACGGCCTACG
ATCGGGGAGCAGAAGCAGCCATTACAGCGGCTTTTGCACGAATGCAGCAGATCGAGGCCGCCATTGGACGGCAGGAATTT
TCAGATCTGAACAGGTTGGCCGCTCAGGCCGGTGGACGTCCTCTGAAAGTCGGTGACGATACATGGCAGATCCTTTCCCT
GGCTGCCGAATACTGGCAGAAGACGGACGGGGCCTTCGATGTAACCGTCAATCCCCTGCTGGAATTGTGGGGATTCGGTT
ATGACGGCGAGGGTAATTTCCCTGAGCCCGCAGCGATTCAAGCCGCCCTTCCCAAAGTCGGCGGTAACAAACTGCTCCTT
TTCCCGGAAAAACGGGAAATCCAGCTGGTGAAACCCGGAATGTCCCTGACCGTAGGCGGCATCGCAAAGGGCTACGCCGT
GGAGGAGGCCGCCAAGGTCCTCAAAAGGAACGGCATCAAGAACGCCATGATCAACGGAGGCAGCAGCATCAAGGTGATCG
GGGACGGACCCGGCGGGCGCGGCTGGAGAATCGGTGTGGAAAACCCCCGTGAGGCAGGCAGGCTTGTCGGGGTGATAGTC
CTGCATTCCGGGGACGCCATGGGCACTTCCGCGGACAACAAGCGTTTTTTTATCAGGGACAGTCACCGCTATTCCCATAT
CATCGATCCGCGTACCGGGTGGCCCGCTCCGGAAAAGATGACACTGGTAACTGTGGTGACCCGGAATGCCGCAACCGCGG
ATATCCTTACAAAAGCCCTTTTTTTAAACGATCTGAACTGGAGCATGAGATTCCTTGAACAGGAAAACCTGAAGGCGGTG
CTGATCGATACCCAGGGGAAAATTCATACGACCCCGGGCTTTCAATTACTGAGGCAATCATGA

Upstream 100 bases:

>100_bases
CGGAAACAGGGTTATCCCCCTGATGAATCTCTTCAACTTGATGATTGCCTGTTTCTATAAAAAAATACGAAATTTTATAC
CCTTGATGGTACATGATTAA

Downstream 100 bases:

>100_bases
TCAGGGTCGAGGACGTCACCCATTCATTCAACAGCCATAAGGCCCTGAACAACCTGTCTTTTCATGTCGCACCGGGAGAA
TGCTTCGGTCTCCTCGGTCC

Product: iron-sulfur cluster assembly/repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRSMTKTTQKMIFGIILTGSMLGFFWMAWSRIANEPLVRSRLMMGTIIEITAYDRGAEAAITAAFARMQQIEAAIGRQEF
SDLNRLAAQAGGRPLKVGDDTWQILSLAAEYWQKTDGAFDVTVNPLLELWGFGYDGEGNFPEPAAIQAALPKVGGNKLLL
FPEKREIQLVKPGMSLTVGGIAKGYAVEEAAKVLKRNGIKNAMINGGSSIKVIGDGPGGRGWRIGVENPREAGRLVGVIV
LHSGDAMGTSADNKRFFIRDSHRYSHIIDPRTGWPAPEKMTLVTVVTRNAATADILTKALFLNDLNWSMRFLEQENLKAV
LIDTQGKIHTTPGFQLLRQS

Sequences:

>Translated_340_residues
MRSMTKTTQKMIFGIILTGSMLGFFWMAWSRIANEPLVRSRLMMGTIIEITAYDRGAEAAITAAFARMQQIEAAIGRQEF
SDLNRLAAQAGGRPLKVGDDTWQILSLAAEYWQKTDGAFDVTVNPLLELWGFGYDGEGNFPEPAAIQAALPKVGGNKLLL
FPEKREIQLVKPGMSLTVGGIAKGYAVEEAAKVLKRNGIKNAMINGGSSIKVIGDGPGGRGWRIGVENPREAGRLVGVIV
LHSGDAMGTSADNKRFFIRDSHRYSHIIDPRTGWPAPEKMTLVTVVTRNAATADILTKALFLNDLNWSMRFLEQENLKAV
LIDTQGKIHTTPGFQLLRQS
>Mature_340_residues
MRSMTKTTQKMIFGIILTGSMLGFFWMAWSRIANEPLVRSRLMMGTIIEITAYDRGAEAAITAAFARMQQIEAAIGRQEF
SDLNRLAAQAGGRPLKVGDDTWQILSLAAEYWQKTDGAFDVTVNPLLELWGFGYDGEGNFPEPAAIQAALPKVGGNKLLL
FPEKREIQLVKPGMSLTVGGIAKGYAVEEAAKVLKRNGIKNAMINGGSSIKVIGDGPGGRGWRIGVENPREAGRLVGVIV
LHSGDAMGTSADNKRFFIRDSHRYSHIIDPRTGWPAPEKMTLVTVVTRNAATADILTKALFLNDLNWSMRFLEQENLKAV
LIDTQGKIHTTPGFQLLRQS

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=261, Percent_Identity=27.2030651340996, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 37261; Mature: 37261

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSMTKTTQKMIFGIILTGSMLGFFWMAWSRIANEPLVRSRLMMGTIIEITAYDRGAEAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEECCCCCHHH
ITAAFARMQQIEAAIGRQEFSDLNRLAAQAGGRPLKVGDDTWQILSLAAEYWQKTDGAFD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCEEE
VTVNPLLELWGFGYDGEGNFPEPAAIQAALPKVGGNKLLLFPEKREIQLVKPGMSLTVGG
EEHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCEEEECCCCEEEECC
IAKGYAVEEAAKVLKRNGIKNAMINGGSSIKVIGDGPGGRGWRIGVENPREAGRLVGVIV
CCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCEEEECCCCHHHCCCEEEEEE
LHSGDAMGTSADNKRFFIRDSHRYSHIIDPRTGWPAPEKMTLVTVVTRNAATADILTKAL
EECCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
FLNDLNWSMRFLEQENLKAVLIDTQGKIHTTPGFQLLRQS
HHHCCCHHHHHHHHCCCEEEEEECCCCEECCCCHHHHCCC
>Mature Secondary Structure
MRSMTKTTQKMIFGIILTGSMLGFFWMAWSRIANEPLVRSRLMMGTIIEITAYDRGAEAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCEEEEEEECCCCCHHH
ITAAFARMQQIEAAIGRQEFSDLNRLAAQAGGRPLKVGDDTWQILSLAAEYWQKTDGAFD
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCEEE
VTVNPLLELWGFGYDGEGNFPEPAAIQAALPKVGGNKLLLFPEKREIQLVKPGMSLTVGG
EEHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCEEEECCCCEEEECC
IAKGYAVEEAAKVLKRNGIKNAMINGGSSIKVIGDGPGGRGWRIGVENPREAGRLVGVIV
CCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCCEEEECCCCHHHCCCEEEEEE
LHSGDAMGTSADNKRFFIRDSHRYSHIIDPRTGWPAPEKMTLVTVVTRNAATADILTKAL
EECCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
FLNDLNWSMRFLEQENLKAVLIDTQGKIHTTPGFQLLRQS
HHHCCCHHHHHHHHCCCEEEEEECCCCEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]