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The map label for this gene is 85860764

Identifier: 85860764

GI number: 85860764

Start: 2940610

End: 2942205

Strand: Direct

Name: 85860764

Synonym: SYN_00357

Alternate gene names: NA

Gene position: 2940610-2942205 (Clockwise)

Preceding gene: 85860760

Following gene: 85860779

Centisome position: 92.49

GC content: 58.46

Gene sequence:

>1596_bases
ATGGACGTTGGCAATATGCACTTGATAAAAACTCTCTCAATGGATATTGTTCGGGTTGTTTTTTCCCAAACAAGGAGCCC
CCTCATGATGAAAATCCTTCTTGCCGGCTATAATCTGGATTATGAAACGATCCGGGAGTTGCAGGCAGCCCGGCCTGAAT
TGCGCAACCTGACCCCGGAAACGATCTCTGCCGCCTATGCCCGCATCAGCCGCGATCCCCGGCCTGTCCATGAGCTGCGG
GCCGTTGCCCGGGAGGAAGTAGAAAAGGCGCGGCAGTCCAACCGGACTATCGTTTTCGGTCTGGGGCACAGCTCCGTCGC
CGAACATGCCGTTTTCAATATCGATATTCTGGGAATTTCCCGACTGCTCGTGGAGGAAATCCAGCGGTTCCGCCTCTGCT
CCTACACGGAGAAATCCCAACGATACATCCTGCTGACCGATGATTTCGTGATTCCGGAAGAGATCCGGGATACGGGGCTG
GAAGAAATCTTTCGAGAGACCGTCCGGGAGCAGAATTCCCTTTATCATACCTTATATGCCCGGCTCCTGCCTCACGTTCT
GGAAAAAAATCCGGAAATGGCCGCTGTCCCGGAAAAGCGGTCCACCCTGGAAGGCTGGGCCAAGGAGGATGCCCGCTACA
TCGTTTCCCTGGCGACGGAGGCCCAGTTGGGGATGACCCTCAACGCTCGCGGTCTGGAACTCCTGCTGAGGCGGTTCGCC
GCTCATCCCCTGGAGGAGTGCCGGGCTTTCAGTCAACATCTTTATGAAAAGACGTTTGAGATTGCGCCGTCACTGATCCG
CTATACCGAACCCACCCCCTTCGATCGGGACACCCCGACGGCGCTGCGCCGGATGACAGACGAGCTGATCGCCCGCCATG
CCGCCGGGCCGGAAGAGGAGGAAAGGAACAGTGAAAACCGGAAAGACTGGCAACGAGGTGACGTCCGTCTGATCGACGCC
TCGCCCGATGCCGATGACCGCATCCTGGCGGCACTGCTCCATACCTCTTCCAGGGCGCCTCTTGACCGCTGTCGGAATCT
TCTGCACCGGATGGATACCGTCGAGAAGATCGCTCTTCTCAAGGAGGCCTTCCGGTTTCTTTCGGAACATGACGCAGTTC
AACGGGAATTTGAATACGCTGACCTCACCTTTGAGCTGACCCTCTCCGCGAGCTGCTTCGCCCAGCTCAAACGGCACCGG
ATGGCCACCCTCACCGTCCAGGATTACAACCCCGATCTCAGTGTCACAATCCCCCCCGCCATTATCGAAGTCGGCATGGA
ATCTGCCTTCCGCGAAGTCATCGACCGGACGGAAGCCATCTACCGGCAAATCGCGCAAACCGTTCCTCAGGCCGCTCCCT
ACATTCTTACCAACGCTCACCGCCGCCGGGCTATCCTCAAGGTCAACGCCCGGGAGCTCTACCACATGGCCCGCCTGCGT
CTCGACGCTCACGCCCAGTGGGATATCCGCCGGCTCACCGGCAACATGCTGACACTGGCCCGGAAGGTCATGCCCCTGAC
CCTTCTGCTGGCCACGGGAAAGGATGGCTTCGCAGCGGCATACGGGACCCTTTTTTCGGACCGGCAGCAAGAATAG

Upstream 100 bases:

>100_bases
AAAAATTTTCCATGGTCGGCTGCTTGGTCGGTATCGGCAAGTTTCTTCAGTATTACGGGAATTAGAGACAAGCTCCGCCT
TTATCCTGAAACTGCGAGAG

Downstream 100 bases:

>100_bases
ATTTTCGGTGCAACCCCCTATTTCTCATATTCCTTCCGGAGACGCTCCAGTCCCTTTCGATAGCTTTCGCCATCGCCGTA
CTCAAAAAATTTTGGATAGC

Product: thymidylate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MDVGNMHLIKTLSMDIVRVVFSQTRSPLMMKILLAGYNLDYETIRELQAARPELRNLTPETISAAYARISRDPRPVHELR
AVAREEVEKARQSNRTIVFGLGHSSVAEHAVFNIDILGISRLLVEEIQRFRLCSYTEKSQRYILLTDDFVIPEEIRDTGL
EEIFRETVREQNSLYHTLYARLLPHVLEKNPEMAAVPEKRSTLEGWAKEDARYIVSLATEAQLGMTLNARGLELLLRRFA
AHPLEECRAFSQHLYEKTFEIAPSLIRYTEPTPFDRDTPTALRRMTDELIARHAAGPEEEERNSENRKDWQRGDVRLIDA
SPDADDRILAALLHTSSRAPLDRCRNLLHRMDTVEKIALLKEAFRFLSEHDAVQREFEYADLTFELTLSASCFAQLKRHR
MATLTVQDYNPDLSVTIPPAIIEVGMESAFREVIDRTEAIYRQIAQTVPQAAPYILTNAHRRRAILKVNARELYHMARLR
LDAHAQWDIRRLTGNMLTLARKVMPLTLLLATGKDGFAAAYGTLFSDRQQE

Sequences:

>Translated_531_residues
MDVGNMHLIKTLSMDIVRVVFSQTRSPLMMKILLAGYNLDYETIRELQAARPELRNLTPETISAAYARISRDPRPVHELR
AVAREEVEKARQSNRTIVFGLGHSSVAEHAVFNIDILGISRLLVEEIQRFRLCSYTEKSQRYILLTDDFVIPEEIRDTGL
EEIFRETVREQNSLYHTLYARLLPHVLEKNPEMAAVPEKRSTLEGWAKEDARYIVSLATEAQLGMTLNARGLELLLRRFA
AHPLEECRAFSQHLYEKTFEIAPSLIRYTEPTPFDRDTPTALRRMTDELIARHAAGPEEEERNSENRKDWQRGDVRLIDA
SPDADDRILAALLHTSSRAPLDRCRNLLHRMDTVEKIALLKEAFRFLSEHDAVQREFEYADLTFELTLSASCFAQLKRHR
MATLTVQDYNPDLSVTIPPAIIEVGMESAFREVIDRTEAIYRQIAQTVPQAAPYILTNAHRRRAILKVNARELYHMARLR
LDAHAQWDIRRLTGNMLTLARKVMPLTLLLATGKDGFAAAYGTLFSDRQQE
>Mature_531_residues
MDVGNMHLIKTLSMDIVRVVFSQTRSPLMMKILLAGYNLDYETIRELQAARPELRNLTPETISAAYARISRDPRPVHELR
AVAREEVEKARQSNRTIVFGLGHSSVAEHAVFNIDILGISRLLVEEIQRFRLCSYTEKSQRYILLTDDFVIPEEIRDTGL
EEIFRETVREQNSLYHTLYARLLPHVLEKNPEMAAVPEKRSTLEGWAKEDARYIVSLATEAQLGMTLNARGLELLLRRFA
AHPLEECRAFSQHLYEKTFEIAPSLIRYTEPTPFDRDTPTALRRMTDELIARHAAGPEEEERNSENRKDWQRGDVRLIDA
SPDADDRILAALLHTSSRAPLDRCRNLLHRMDTVEKIALLKEAFRFLSEHDAVQREFEYADLTFELTLSASCFAQLKRHR
MATLTVQDYNPDLSVTIPPAIIEVGMESAFREVIDRTEAIYRQIAQTVPQAAPYILTNAHRRRAILKVNARELYHMARLR
LDAHAQWDIRRLTGNMLTLARKVMPLTLLLATGKDGFAAAYGTLFSDRQQE

Specific function: Unknown

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 thyX (flavin-dependent thymidylate synthase) domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: NA

Molecular weight: Translated: 61030; Mature: 61030

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVGNMHLIKTLSMDIVRVVFSQTRSPLMMKILLAGYNLDYETIRELQAARPELRNLTPE
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCHH
TISAAYARISRDPRPVHELRAVAREEVEKARQSNRTIVFGLGHSSVAEHAVFNIDILGIS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHEEEEHHHHH
RLLVEEIQRFRLCSYTEKSQRYILLTDDFVIPEEIRDTGLEEIFRETVREQNSLYHTLYA
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RLLPHVLEKNPEMAAVPEKRSTLEGWAKEDARYIVSLATEAQLGMTLNARGLELLLRRFA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHH
AHPLEECRAFSQHLYEKTFEIAPSLIRYTEPTPFDRDTPTALRRMTDELIARHAAGPEEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
ERNSENRKDWQRGDVRLIDASPDADDRILAALLHTSSRAPLDRCRNLLHRMDTVEKIALL
HHCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KEAFRFLSEHDAVQREFEYADLTFELTLSASCFAQLKRHRMATLTVQDYNPDLSVTIPPA
HHHHHHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHHCCEEEEEEECCCCCCEEECCHH
IIEVGMESAFREVIDRTEAIYRQIAQTVPQAAPYILTNAHRRRAILKVNARELYHMARLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHEEECHHHHHHHHHHH
LDAHAQWDIRRLTGNMLTLARKVMPLTLLLATGKDGFAAAYGTLFSDRQQE
HCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDVGNMHLIKTLSMDIVRVVFSQTRSPLMMKILLAGYNLDYETIRELQAARPELRNLTPE
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCHH
TISAAYARISRDPRPVHELRAVAREEVEKARQSNRTIVFGLGHSSVAEHAVFNIDILGIS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHEEEEHHHHH
RLLVEEIQRFRLCSYTEKSQRYILLTDDFVIPEEIRDTGLEEIFRETVREQNSLYHTLYA
HHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RLLPHVLEKNPEMAAVPEKRSTLEGWAKEDARYIVSLATEAQLGMTLNARGLELLLRRFA
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHH
AHPLEECRAFSQHLYEKTFEIAPSLIRYTEPTPFDRDTPTALRRMTDELIARHAAGPEEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
ERNSENRKDWQRGDVRLIDASPDADDRILAALLHTSSRAPLDRCRNLLHRMDTVEKIALL
HHCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KEAFRFLSEHDAVQREFEYADLTFELTLSASCFAQLKRHRMATLTVQDYNPDLSVTIPPA
HHHHHHHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHHCCEEEEEEECCCCCCEEECCHH
IIEVGMESAFREVIDRTEAIYRQIAQTVPQAAPYILTNAHRRRAILKVNARELYHMARLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHEEECHHHHHHHHHHH
LDAHAQWDIRRLTGNMLTLARKVMPLTLLLATGKDGFAAAYGTLFSDRQQE
HCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]