Click here to switch to the map view.

The map label for this gene is fadR [H]

Identifier: 85860706

GI number: 85860706

Start: 2887131

End: 2887802

Strand: Direct

Name: fadR [H]

Synonym: SYN_02416

Alternate gene names: 85860706

Gene position: 2887131-2887802 (Clockwise)

Preceding gene: 85860694

Following gene: 85860710

Centisome position: 90.81

GC content: 41.52

Gene sequence:

>672_bases
TTGGCAGCAAACTCTGATAAAATAAATAACCTTAAAACATCAAAGGCTAATCATATAAAAGAGAAAAAGAGACTTCTCAG
CAAGAAAGCGGAAAACACCAGAGACCGGATTGTAGAGAGTGCGAAGATTCTTTTTGCGGAAAATGGGTTTCTAAAGACAA
CAGTTGTGGACATCTGTCGCAACGTCGGTCTTTCCGAAGCCGCATTATATGAACATTTCAAAGGCAAGGAAGACCTTTTG
CTGGCCATCCCGGATTTATGGGTCTCTGAATTACTGAAAGACTTGGATGATCAGATGTTCGGGGTAAAGGGTGCATTCAA
TAAGCTGCGAAAATACATCTGGTGGACATATCGTCGGACGGAGGAAGCACCAGTTGATGCAAAGATTGTCTACTTGTTTC
TGAAAACCAGTTCCAGCTTTATGGAAACATCCGTCTACCAGAATGTCAGACTCCTTTACCATTATCTCATTGATATATTT
GAAGAAGGCAAAAAATCCGGAGAGATGAGGCAGGATATTGATTCATCGGTAGCGCAGAGTATTGTGATCGGAACTATGGA
TCACATGATTACGCTTTGGCTGCTTAAGAACATGTCTTACTCACTGTTTGAGAAAGCAGAAGAAACCTTTGATCTCTTAG
AGAGTGCCTTTTCCAGTAAAGAGCGTTCCTGA

Upstream 100 bases:

>100_bases
AAATAAAAATTACTTTTTATGCTTGTTAGGCTGATTGACTTGTGTTAGGGAGAGTATTACCTAATGACATTAGTATCATT
GGAGAGGGGAAAAATTAGAA

Downstream 100 bases:

>100_bases
ATGAACTTTCATTTGCAGATTGAAATGCGTTGCCTGGAGGCAGAATATCAAGTTGTTGAATTCAGTGACTTTGATTCCGT
CGGCAATCTGATATCGAGTG

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MAANSDKINNLKTSKANHIKEKKRLLSKKAENTRDRIVESAKILFAENGFLKTTVVDICRNVGLSEAALYEHFKGKEDLL
LAIPDLWVSELLKDLDDQMFGVKGAFNKLRKYIWWTYRRTEEAPVDAKIVYLFLKTSSSFMETSVYQNVRLLYHYLIDIF
EEGKKSGEMRQDIDSSVAQSIVIGTMDHMITLWLLKNMSYSLFEKAEETFDLLESAFSSKERS

Sequences:

>Translated_223_residues
MAANSDKINNLKTSKANHIKEKKRLLSKKAENTRDRIVESAKILFAENGFLKTTVVDICRNVGLSEAALYEHFKGKEDLL
LAIPDLWVSELLKDLDDQMFGVKGAFNKLRKYIWWTYRRTEEAPVDAKIVYLFLKTSSSFMETSVYQNVRLLYHYLIDIF
EEGKKSGEMRQDIDSSVAQSIVIGTMDHMITLWLLKNMSYSLFEKAEETFDLLESAFSSKERS
>Mature_222_residues
AANSDKINNLKTSKANHIKEKKRLLSKKAENTRDRIVESAKILFAENGFLKTTVVDICRNVGLSEAALYEHFKGKEDLLL
AIPDLWVSELLKDLDDQMFGVKGAFNKLRKYIWWTYRRTEEAPVDAKIVYLFLKTSSSFMETSVYQNVRLLYHYLIDIFE
EGKKSGEMRQDIDSSVAQSIVIGTMDHMITLWLLKNMSYSLFEKAEETFDLLESAFSSKERS

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 25772; Mature: 25641

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAANSDKINNLKTSKANHIKEKKRLLSKKAENTRDRIVESAKILFAENGFLKTTVVDICR
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NVGLSEAALYEHFKGKEDLLLAIPDLWVSELLKDLDDQMFGVKGAFNKLRKYIWWTYRRT
CCCCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EEAPVDAKIVYLFLKTSSSFMETSVYQNVRLLYHYLIDIFEEGKKSGEMRQDIDSSVAQS
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
IVIGTMDHMITLWLLKNMSYSLFEKAEETFDLLESAFSSKERS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AANSDKINNLKTSKANHIKEKKRLLSKKAENTRDRIVESAKILFAENGFLKTTVVDICR
CCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
NVGLSEAALYEHFKGKEDLLLAIPDLWVSELLKDLDDQMFGVKGAFNKLRKYIWWTYRRT
CCCCHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EEAPVDAKIVYLFLKTSSSFMETSVYQNVRLLYHYLIDIFEEGKKSGEMRQDIDSSVAQS
CCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
IVIGTMDHMITLWLLKNMSYSLFEKAEETFDLLESAFSSKERS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]