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The map label for this gene is amzA [H]

Identifier: 85860593

GI number: 85860593

Start: 2764398

End: 2764970

Strand: Direct

Name: amzA [H]

Synonym: SYN_01286

Alternate gene names: 85860593

Gene position: 2764398-2764970 (Clockwise)

Preceding gene: 85860581

Following gene: 85860595

Centisome position: 86.95

GC content: 57.24

Gene sequence:

>573_bases
ATGGTCATCGGCGCTCAGCCGTGGAGGGAGATAAAGATGATGGAGAACATTCTGCTGATTCCCATAGGCGCTGTCGATTC
GGGCATTCTCGATTCGACGGCCGGCGCGTTACGGGAAATCTTCGGTTGCGAAGCCATGTCAGGAAAATCGCAGCCTGTCC
CACCCGAAACATACGATGCGCGGAGACGCCAATACGCGTCCCACAGAATTCTGAAAATTCTGGAGCCCCTGAAACCGGAC
AGGCACACAATCCTCCTTGGGGTGATCGATTTGGATCTTTATGTTCCGCAACTCAACTTTGTCTTCGGGGAGGCGGATCC
GGCGGCGGGTGTCGCGATCATCGCCCTGCCCCGTCTTCGGCAGGAGTTCTATGGCCTCAAACCCGACAGGGTGATTTTCC
TCCTGCGCGCGGCAAAAGAGGCGATCCACGAACTGGGGCATCTCCAGGGCCTCGACCATTGCCCCGATCCCGGATGCGTC
ATGCATTTCTCGAACAGTCTCAGGGACACGGATGTGAAAGAGGCGCGTTTCTGTGCCGCATGCAGGGAAAGCCTCATGAA
GCCGGGATCATGA

Upstream 100 bases:

>100_bases
CGGTGGGAGACACTTCCCCTGTGTCAGGCCGGCCTGAGTCGGAGACGGGTTATGCCGAGCAGAACGACTGCTTTCAGGCC
GTACACTGGATCCCGGAATC

Downstream 100 bases:

>100_bases
CGGATTCGGAATGGCGTTTCGAAATCAGACAATCTTACAGGTGGTGGAATTCCAGCCTATGAGTCCACCCAGAACGACCG
CCATGTTTTCCCACCCGGCC

Product: zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MVIGAQPWREIKMMENILLIPIGAVDSGILDSTAGALREIFGCEAMSGKSQPVPPETYDARRRQYASHRILKILEPLKPD
RHTILLGVIDLDLYVPQLNFVFGEADPAAGVAIIALPRLRQEFYGLKPDRVIFLLRAAKEAIHELGHLQGLDHCPDPGCV
MHFSNSLRDTDVKEARFCAACRESLMKPGS

Sequences:

>Translated_190_residues
MVIGAQPWREIKMMENILLIPIGAVDSGILDSTAGALREIFGCEAMSGKSQPVPPETYDARRRQYASHRILKILEPLKPD
RHTILLGVIDLDLYVPQLNFVFGEADPAAGVAIIALPRLRQEFYGLKPDRVIFLLRAAKEAIHELGHLQGLDHCPDPGCV
MHFSNSLRDTDVKEARFCAACRESLMKPGS
>Mature_190_residues
MVIGAQPWREIKMMENILLIPIGAVDSGILDSTAGALREIFGCEAMSGKSQPVPPETYDARRRQYASHRILKILEPLKPD
RHTILLGVIDLDLYVPQLNFVFGEADPAAGVAIIALPRLRQEFYGLKPDRVIFLLRAAKEAIHELGHLQGLDHCPDPGCV
MHFSNSLRDTDVKEARFCAACRESLMKPGS

Specific function: Probable zinc metalloprotease [H]

COG id: COG1913

COG function: function code R; Predicted Zn-dependent proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M54 family [H]

Homologues:

Organism=Homo sapiens, GI75812974, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI75812972, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI75812970, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI75812968, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI75812966, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI75812976, Length=142, Percent_Identity=32.3943661971831, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012962
- InterPro:   IPR012091 [H]

Pfam domain/function: PF07998 Peptidase_M54 [H]

EC number: NA

Molecular weight: Translated: 21071; Mature: 21071

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIGAQPWREIKMMENILLIPIGAVDSGILDSTAGALREIFGCEAMSGKSQPVPPETYDA
CCCCCCCHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
RRRQYASHRILKILEPLKPDRHTILLGVIDLDLYVPQLNFVFGEADPAAGVAIIALPRLR
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHEEECCCHHEEECCCCCCCCEEEEHHHHHH
QEFYGLKPDRVIFLLRAAKEAIHELGHLQGLDHCPDPGCVMHFSNSLRDTDVKEARFCAA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHCCCCCCCCHHHHHHHHH
CRESLMKPGS
HHHHHCCCCC
>Mature Secondary Structure
MVIGAQPWREIKMMENILLIPIGAVDSGILDSTAGALREIFGCEAMSGKSQPVPPETYDA
CCCCCCCHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
RRRQYASHRILKILEPLKPDRHTILLGVIDLDLYVPQLNFVFGEADPAAGVAIIALPRLR
HHHHHHHHHHHHHHHCCCCCCCEEEEEEEEHEEECCCHHEEECCCCCCCCEEEEHHHHHH
QEFYGLKPDRVIFLLRAAKEAIHELGHLQGLDHCPDPGCVMHFSNSLRDTDVKEARFCAA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHCCCCCCCCHHHHHHHHH
CRESLMKPGS
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]