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The map label for this gene is mrp [H]

Identifier: 85860401

GI number: 85860401

Start: 2569611

End: 2570327

Strand: Direct

Name: mrp [H]

Synonym: SYN_03124

Alternate gene names: 85860401

Gene position: 2569611-2570327 (Clockwise)

Preceding gene: 85860400

Following gene: 85860402

Centisome position: 80.82

GC content: 55.37

Gene sequence:

>717_bases
ATGATCGATGAGCAGAAGGTTCGAGAGGTCCTCAAACTCATCCTGGATCCCGAGCTGAAAAAGAGTCTGCTGGACCTGGG
AATGATTCGGGATGTCTGCGTGAAAAAGGATCGGGTCAGCCTGACCCTTGCCCTTACCACGGTGAAGTGCCCTAAAAAAG
ATGCCATCGTGGCTGAGATCAAGCGCGTGCTTATGGCCTTGCCCGGGATCGCCGGGGTCGATGTCGAGTTGACGACGCTG
AACCGGGAAGAACTGCATTCATTGTTCCCGAAACATCCTCTGGTCGGCCTGGACAAAGTGCGCCATGTCCTGGCTGTTGC
CAGCGGCAAAGGCGGGGTGGGAAAAACAACTATCGCCGTAAATGTCGCCCTGGCCCTGGCTCGAAAGGGCAACCGGGTCG
GCCTGCTCGATGCGGATGTTTATGGCCCAAGCATTCCGATCATGCTGGCCATCGATGATTCCCCTGAATGGGAAAATCAG
ATGATTCTTCCTATTGAAAAGTTCGGACTCAGGATTATGTCATTGGGCATGCTCACCGCAGAGGGCCAGTCCATTGTCTG
GCGCGGCCCTCTGGTTTCCAGGGCCATCAAGCAATTGCTGGGCGAGGTTATGTGGGGCGATCTGGATTATCTGGGTTTGT
GGATCTCCCTCCTGGAACCGGAGATCCTTCCATCACGATCGCTCAATCCATTCCCACCGCTGCCGTCCTTATGGTGA

Upstream 100 bases:

>100_bases
GGCAAAAAAGGCTGTCATAAATCAAAGGTCATTAACACGGAAAAGATTTCGGCGATGAATGCAGAATTGAAAACAAAACA
TTGCAAGGAAGGTCGTTGTC

Downstream 100 bases:

>100_bases
CAACGCCACAGGAAGTCGCCCTGGCCGATGTCCGCAGGGCCATTAATTTGTTCAAAAAATTCGAGATAAACATGATCGGC
CTTGTGGAAAACATGTCTTA

Product: cytoplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIDEQKVREVLKLILDPELKKSLLDLGMIRDVCVKKDRVSLTLALTTVKCPKKDAIVAEIKRVLMALPGIAGVDVELTTL
NREELHSLFPKHPLVGLDKVRHVLAVASGKGGVGKTTIAVNVALALARKGNRVGLLDADVYGPSIPIMLAIDDSPEWENQ
MILPIEKFGLRIMSLGMLTAEGQSIVWRGPLVSRAIKQLLGEVMWGDLDYLGLWISLLEPEILPSRSLNPFPPLPSLW

Sequences:

>Translated_238_residues
MIDEQKVREVLKLILDPELKKSLLDLGMIRDVCVKKDRVSLTLALTTVKCPKKDAIVAEIKRVLMALPGIAGVDVELTTL
NREELHSLFPKHPLVGLDKVRHVLAVASGKGGVGKTTIAVNVALALARKGNRVGLLDADVYGPSIPIMLAIDDSPEWENQ
MILPIEKFGLRIMSLGMLTAEGQSIVWRGPLVSRAIKQLLGEVMWGDLDYLGLWISLLEPEILPSRSLNPFPPLPSLW
>Mature_238_residues
MIDEQKVREVLKLILDPELKKSLLDLGMIRDVCVKKDRVSLTLALTTVKCPKKDAIVAEIKRVLMALPGIAGVDVELTTL
NREELHSLFPKHPLVGLDKVRHVLAVASGKGGVGKTTIAVNVALALARKGNRVGLLDADVYGPSIPIMLAIDDSPEWENQ
MILPIEKFGLRIMSLGMLTAEGQSIVWRGPLVSRAIKQLLGEVMWGDLDYLGLWISLLEPEILPSRSLNPFPPLPSLW

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=155, Percent_Identity=43.2258064516129, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI6912540, Length=121, Percent_Identity=44.6280991735537, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI118572611, Length=119, Percent_Identity=37.8151260504202, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI87082045, Length=213, Percent_Identity=37.0892018779343, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25143050, Length=123, Percent_Identity=36.5853658536585, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322188, Length=126, Percent_Identity=38.8888888888889, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321347, Length=141, Percent_Identity=37.5886524822695, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221511043, Length=122, Percent_Identity=45.9016393442623, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24667611, Length=120, Percent_Identity=41.6666666666667, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921440, Length=116, Percent_Identity=37.0689655172414, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR002744
- InterPro:   IPR000808 [H]

Pfam domain/function: PF01883 DUF59; PF09140 MipZ; PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 26159; Mature: 26159

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEQKVREVLKLILDPELKKSLLDLGMIRDVCVKKDRVSLTLALTTVKCPKKDAIVAEI
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHH
KRVLMALPGIAGVDVELTTLNREELHSLFPKHPLVGLDKVRHVLAVASGKGGVGKTTIAV
HHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
NVALALARKGNRVGLLDADVYGPSIPIMLAIDDSPEWENQMILPIEKFGLRIMSLGMLTA
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHEEEE
EGQSIVWRGPLVSRAIKQLLGEVMWGDLDYLGLWISLLEPEILPSRSLNPFPPLPSLW
CCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDEQKVREVLKLILDPELKKSLLDLGMIRDVCVKKDRVSLTLALTTVKCPKKDAIVAEI
CCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCHHHHHH
KRVLMALPGIAGVDVELTTLNREELHSLFPKHPLVGLDKVRHVLAVASGKGGVGKTTIAV
HHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
NVALALARKGNRVGLLDADVYGPSIPIMLAIDDSPEWENQMILPIEKFGLRIMSLGMLTA
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHEEEE
EGQSIVWRGPLVSRAIKQLLGEVMWGDLDYLGLWISLLEPEILPSRSLNPFPPLPSLW
CCCEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]