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The map label for this gene is stc [H]

Identifier: 85860370

GI number: 85860370

Start: 2545626

End: 2546993

Strand: Direct

Name: stc [H]

Synonym: SYN_01191

Alternate gene names: 85860370

Gene position: 2545626-2546993 (Clockwise)

Preceding gene: 85860367

Following gene: 85860372

Centisome position: 80.07

GC content: 57.24

Gene sequence:

>1368_bases
ATGAGCAAACAGAGAGAAAAGACCGCCCCCCGGGAAAGGGACACCATTCTTGATTCCATCGCGGACGGGGTTTTTTCCGT
GGACGACCGGTGGCGCATCACGTCCTTCAATCGCGCGGCGGAGAAGATTACCGGCGTTTCCCGCGAGGATGCCGTGGGAC
AGCGCTGCAAGGATGTACTCAAGGCCGAGATCTGCGACCGCGGCTGCCTTCTGAAGAAAACCATGGAAACGGGAAAACCG
GTGGTCAACCGCACGGTCTACATCGTCAATGCCGAAGGCCGGCGGCTGCCCATCAGCATCTCCACGGCGCTGCTGCGCGA
CGAAGACGACCGGATTATCGGCGCCGTGGAAACATTTCGGGATCTCAGTCTGGAAGAGCAGCTTCGAAAGAAGATCGAAG
CACGCTATTCCTTCGAGGACATCATCTCCCGGAATCACCGGATGCATGAACTCTTCAGCATTCTTCCGGATATAGCAAAC
AGCACCAGCACGGTTCTCATCGAGGGTGAGAGCGGCACGGGAAAGGAACTCGTCGCCAGGGCCATTCACAACCTCAGTAC
GCGGAAAAGCAGACCCTTTGTTGCAGTCAATTGCGGCGCCCTGCCGGATACGCTTCTGGAATCGGAACTGTTCGGGTACA
AGGCCGGCGCCTTCACGGATGCGCGGAAGGACAAGCCGGGCCGCTTCAAACTGGCGGAGAAAGGCACCCTTTTCCTCGAT
GAAATCGGAGACGTCTCGCCGGCCATGCAGGTCCGGCTGCTTCGCGTCCTCCAGGAAAAGACCTATGAACCCCTGGGATC
CGTGGAAAGTGTCCGGCACGATGTCCGGATAATCGCGGCAACAAACAAAAAACTCCCGGACCTGGTCAGGGAAGGCAAAT
TCCGGGAGGATCTCTATTACCGGATCAACATCGTCAGGCTGGAACTCCCCCCCCTACGGGAAAGAATGGAGGACATTCCC
CTGCTGGTCGATCACTTCATCGGACATTTCAACGTTCTTCAGAACAAGGAGATCGCCGGGGTGACCGATGAAGCCCTGGC
CTGCCTGATGACCTATACATATCCCGGCAACATCCGGGAGCTGGAGAACATTATCGAACGTGCCTTCATCCTCTGCAAAT
CCGGGATGATCGACCGGATCCACCTGCCTGACCCGGTTTGCGGGATCTCCGGCGCCGCTGAGATCCCGGCGTGGGAATCC
ATGTCCTTCCGGGATATGGAAGCAATATTTCTGACCAACGTTCTCCGGAGGAACGCCTGGAACAAAAGCCGGACCGCCCG
GGAACTCGGGATTCACAAAAGCACCCTTTTCCGGAAGCTGAAGGCTCTGGGCATTCGCTCACCCGACAAAACTCAGGAAA
AATCATGA

Upstream 100 bases:

>100_bases
AATATCTATTCAATTGAACTTTTTTCTGATAAGCACCTTTTAAAGCGGCCATTAATGAACCGAACTGCTGATTCTTATAC
AAAGACTGCAGAGAAAAGCA

Downstream 100 bases:

>100_bases
TGCCTTACAAAGAGACCCGGAGCATCCTTCTCTCCATATTCGATTGTTTTTACCAGGCTTCCATCATCGGGCGCGCCGAC
GCTGCGCAGCCGCAATTACC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSKQREKTAPRERDTILDSIADGVFSVDDRWRITSFNRAAEKITGVSREDAVGQRCKDVLKAEICDRGCLLKKTMETGKP
VVNRTVYIVNAEGRRLPISISTALLRDEDDRIIGAVETFRDLSLEEQLRKKIEARYSFEDIISRNHRMHELFSILPDIAN
STSTVLIEGESGTGKELVARAIHNLSTRKSRPFVAVNCGALPDTLLESELFGYKAGAFTDARKDKPGRFKLAEKGTLFLD
EIGDVSPAMQVRLLRVLQEKTYEPLGSVESVRHDVRIIAATNKKLPDLVREGKFREDLYYRINIVRLELPPLRERMEDIP
LLVDHFIGHFNVLQNKEIAGVTDEALACLMTYTYPGNIRELENIIERAFILCKSGMIDRIHLPDPVCGISGAAEIPAWES
MSFRDMEAIFLTNVLRRNAWNKSRTARELGIHKSTLFRKLKALGIRSPDKTQEKS

Sequences:

>Translated_455_residues
MSKQREKTAPRERDTILDSIADGVFSVDDRWRITSFNRAAEKITGVSREDAVGQRCKDVLKAEICDRGCLLKKTMETGKP
VVNRTVYIVNAEGRRLPISISTALLRDEDDRIIGAVETFRDLSLEEQLRKKIEARYSFEDIISRNHRMHELFSILPDIAN
STSTVLIEGESGTGKELVARAIHNLSTRKSRPFVAVNCGALPDTLLESELFGYKAGAFTDARKDKPGRFKLAEKGTLFLD
EIGDVSPAMQVRLLRVLQEKTYEPLGSVESVRHDVRIIAATNKKLPDLVREGKFREDLYYRINIVRLELPPLRERMEDIP
LLVDHFIGHFNVLQNKEIAGVTDEALACLMTYTYPGNIRELENIIERAFILCKSGMIDRIHLPDPVCGISGAAEIPAWES
MSFRDMEAIFLTNVLRRNAWNKSRTARELGIHKSTLFRKLKALGIRSPDKTQEKS
>Mature_454_residues
SKQREKTAPRERDTILDSIADGVFSVDDRWRITSFNRAAEKITGVSREDAVGQRCKDVLKAEICDRGCLLKKTMETGKPV
VNRTVYIVNAEGRRLPISISTALLRDEDDRIIGAVETFRDLSLEEQLRKKIEARYSFEDIISRNHRMHELFSILPDIANS
TSTVLIEGESGTGKELVARAIHNLSTRKSRPFVAVNCGALPDTLLESELFGYKAGAFTDARKDKPGRFKLAEKGTLFLDE
IGDVSPAMQVRLLRVLQEKTYEPLGSVESVRHDVRIIAATNKKLPDLVREGKFREDLYYRINIVRLELPPLRERMEDIPL
LVDHFIGHFNVLQNKEIAGVTDEALACLMTYTYPGNIRELENIIERAFILCKSGMIDRIHLPDPVCGISGAAEIPAWESM
SFRDMEAIFLTNVLRRNAWNKSRTARELGIHKSTLFRKLKALGIRSPDKTQEKS

Specific function: Member Of The Two-Component Regulatory System Zras/Zrar. When Activated By Zras It Acts In Conjunction With Sigma-54 To Regulate The Expression Of Zrap. Positively Autoregulates The Expression Of The Zrasr Operon. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=303, Percent_Identity=47.1947194719472, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1788550, Length=330, Percent_Identity=42.4242424242424, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI87082117, Length=290, Percent_Identity=46.8965517241379, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI1789087, Length=359, Percent_Identity=42.6183844011142, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788905, Length=302, Percent_Identity=43.3774834437086, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789233, Length=451, Percent_Identity=35.0332594235033, Blast_Score=241, Evalue=5e-65,
Organism=Escherichia coli, GI1790299, Length=360, Percent_Identity=39.1666666666667, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI1786524, Length=334, Percent_Identity=38.622754491018, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87082152, Length=301, Percent_Identity=40.1993355481728, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787583, Length=439, Percent_Identity=32.1184510250569, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI87081872, Length=309, Percent_Identity=36.5695792880259, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1789828, Length=317, Percent_Identity=35.3312302839117, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI87081858, Length=443, Percent_Identity=28.4424379232506, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51568; Mature: 51437

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQREKTAPRERDTILDSIADGVFSVDDRWRITSFNRAAEKITGVSREDAVGQRCKDVL
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHH
KAEICDRGCLLKKTMETGKPVVNRTVYIVNAEGRRLPISISTALLRDEDDRIIGAVETFR
HHHHHCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHCCCCCHHHHHHHHHH
DLSLEEQLRKKIEARYSFEDIISRNHRMHELFSILPDIANSTSTVLIEGESGTGKELVAR
HCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
AIHNLSTRKSRPFVAVNCGALPDTLLESELFGYKAGAFTDARKDKPGRFKLAEKGTLFLD
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCEEEH
EIGDVSPAMQVRLLRVLQEKTYEPLGSVESVRHDVRIIAATNKKLPDLVREGKFREDLYY
HHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCEEEEEECCCCCHHHHHCCCCHHCEEE
RINIVRLELPPLRERMEDIPLLVDHFIGHFNVLQNKEIAGVTDEALACLMTYTYPGNIRE
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHH
LENIIERAFILCKSGMIDRIHLPDPVCGISGAAEIPAWESMSFRDMEAIFLTNVLRRNAW
HHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
NKSRTARELGIHKSTLFRKLKALGIRSPDKTQEKS
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKQREKTAPRERDTILDSIADGVFSVDDRWRITSFNRAAEKITGVSREDAVGQRCKDVL
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHH
KAEICDRGCLLKKTMETGKPVVNRTVYIVNAEGRRLPISISTALLRDEDDRIIGAVETFR
HHHHHCCCHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHCCCCCHHHHHHHHHH
DLSLEEQLRKKIEARYSFEDIISRNHRMHELFSILPDIANSTSTVLIEGESGTGKELVAR
HCCHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHH
AIHNLSTRKSRPFVAVNCGALPDTLLESELFGYKAGAFTDARKDKPGRFKLAEKGTLFLD
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCEEEH
EIGDVSPAMQVRLLRVLQEKTYEPLGSVESVRHDVRIIAATNKKLPDLVREGKFREDLYY
HHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCEEEEEECCCCCHHHHHCCCCHHCEEE
RINIVRLELPPLRERMEDIPLLVDHFIGHFNVLQNKEIAGVTDEALACLMTYTYPGNIRE
EEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHH
LENIIERAFILCKSGMIDRIHLPDPVCGISGAAEIPAWESMSFRDMEAIFLTNVLRRNAW
HHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
NKSRTARELGIHKSTLFRKLKALGIRSPDKTQEKS
CHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA