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The map label for this gene is ag45 [H]

Identifier: 85860241

GI number: 85860241

Start: 2434407

End: 2435615

Strand: Direct

Name: ag45 [H]

Synonym: SYN_01580

Alternate gene names: 85860241

Gene position: 2434407-2435615 (Clockwise)

Preceding gene: 85860238

Following gene: 85860244

Centisome position: 76.57

GC content: 53.1

Gene sequence:

>1209_bases
ATGATCACCACAGGAATCATCCTCGGATTGACCCTTTTTGTCTTTGCTGTCGGAAAAAGTCCCGTATTCCGCATCGACAG
GGCAGGGGCGGCCATTATCGGAGCAACCGCAACCATCGCCGCGGGAGCCCTGAGTTTCGACCAGGCGGCACAGGCAATTG
ACCATCGGACATTAGTCCTCCTGTTCTCCATGATGATCATCTCCGCTAATCTCAAACTGGGCGGCTTTTTTGAAAAGACT
GGTGATTTTCTGCTCCGGGCCGCTTCCAGCAGACGGCAGCTGCTCATGGTGATCGTGATGATGAGCGGCCTTCTTTCCGC
TCTGTGCATCAACGACATCGTCTGTCTGCTTTTGACGCCCATAGTCCTGACCGTCTGCCGCCGATCTGGGGCCCCTCCGC
TGCCCCACCTCCTGGGAGTCGCCATGGCCTCAAACATCGGCAGCGCCGCGACCCTGGTAGGCAATCCGCAGAATATTCTG
ATTGCCAGCATTTCCGGCATGTCTTTCATCTCCTATTTCCTGATGGCAGCGCCTGTTGCTGTTGTAAGCCTGTTTGTAAC
TTATATCGTCATTGCCTTCATATTCAGAAAACACCTTGAAGGTCGTCTCGAGCATGGGGAAACGGAAAGTACAGAATACA
ATTCCTATGTCGTGGGCAAATCCCTTCTGGCACTGACCCTGGTTTTGACAGGTTTTCTACTCTCTCTGGACATGGCCGTC
ACCGCCAGCATCGGTGCGGCCTATCTATTGATTACAAGGCGAGTCTCTCCCAACAGGGTCTATGAAAGCGTTGATTTCAA
TCTGCTGGTCATCTTTACGGGACTGTTTGTCATTGTGGGCGGGGTTGAACACACCGGCCTCATGAAGTGGCTGATAGGGA
AGAGTCCTTTTATCGATTTCGGTAATCTTGCTGTTTTCGGCGCGGCAACGGTTGTTCTATCCAACATCTTCAGCAATGTT
CCGGCAGTCATGCTCCTGAAGTACTTTATGCCCCAGCAGAGTTCGGATGTCTGGTGGACGGCGCTGGCCATTTTTTCGAC
CATCGCGGGCAACCTGACGATTACAGGCTCCATTGCCAATCTGATTGTGGCGGAGATCGCTAAAGGCGAACGGATCCGCA
TCGGCTTCTGGGACTATTTCAAGGCAGGATTTCCCCTGACCGTCGTCGTCTCCGCCCTGTCCATGCTGATTCTCTGGCAG
ATATCATGA

Upstream 100 bases:

>100_bases
ATCGCCTGTAACCAGACGACTCGAAATAATTGAATCTAAATCAATCAGGGATTGAAAAAAAATCAAGTTTACTGAAACCG
TTTAAGCGATAGGATCAATA

Downstream 100 bases:

>100_bases
TGATTTCGGATCACAACCCCATGACCAGATTCAGAGATATCCTGTTCGCCTCGCTGAACCGGAAGATTCTGGAATTGGAA
GGACCATTGATTTAACAAAA

Product: asenic pump protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MITTGIILGLTLFVFAVGKSPVFRIDRAGAAIIGATATIAAGALSFDQAAQAIDHRTLVLLFSMMIISANLKLGGFFEKT
GDFLLRAASSRRQLLMVIVMMSGLLSALCINDIVCLLLTPIVLTVCRRSGAPPLPHLLGVAMASNIGSAATLVGNPQNIL
IASISGMSFISYFLMAAPVAVVSLFVTYIVIAFIFRKHLEGRLEHGETESTEYNSYVVGKSLLALTLVLTGFLLSLDMAV
TASIGAAYLLITRRVSPNRVYESVDFNLLVIFTGLFVIVGGVEHTGLMKWLIGKSPFIDFGNLAVFGAATVVLSNIFSNV
PAVMLLKYFMPQQSSDVWWTALAIFSTIAGNLTITGSIANLIVAEIAKGERIRIGFWDYFKAGFPLTVVVSALSMLILWQ
IS

Sequences:

>Translated_402_residues
MITTGIILGLTLFVFAVGKSPVFRIDRAGAAIIGATATIAAGALSFDQAAQAIDHRTLVLLFSMMIISANLKLGGFFEKT
GDFLLRAASSRRQLLMVIVMMSGLLSALCINDIVCLLLTPIVLTVCRRSGAPPLPHLLGVAMASNIGSAATLVGNPQNIL
IASISGMSFISYFLMAAPVAVVSLFVTYIVIAFIFRKHLEGRLEHGETESTEYNSYVVGKSLLALTLVLTGFLLSLDMAV
TASIGAAYLLITRRVSPNRVYESVDFNLLVIFTGLFVIVGGVEHTGLMKWLIGKSPFIDFGNLAVFGAATVVLSNIFSNV
PAVMLLKYFMPQQSSDVWWTALAIFSTIAGNLTITGSIANLIVAEIAKGERIRIGFWDYFKAGFPLTVVVSALSMLILWQ
IS
>Mature_402_residues
MITTGIILGLTLFVFAVGKSPVFRIDRAGAAIIGATATIAAGALSFDQAAQAIDHRTLVLLFSMMIISANLKLGGFFEKT
GDFLLRAASSRRQLLMVIVMMSGLLSALCINDIVCLLLTPIVLTVCRRSGAPPLPHLLGVAMASNIGSAATLVGNPQNIL
IASISGMSFISYFLMAAPVAVVSLFVTYIVIAFIFRKHLEGRLEHGETESTEYNSYVVGKSLLALTLVLTGFLLSLDMAV
TASIGAAYLLITRRVSPNRVYESVDFNLLVIFTGLFVIVGGVEHTGLMKWLIGKSPFIDFGNLAVFGAATVVLSNIFSNV
PAVMLLKYFMPQQSSDVWWTALAIFSTIAGNLTITGSIANLIVAEIAKGERIRIGFWDYFKAGFPLTVVVSALSMLILWQ
IS

Specific function: Unknown

COG id: COG1055

COG function: function code P; Na+/H+ antiporter NhaD and related arsenite permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

Organism=Escherichia coli, GI1787039, Length=335, Percent_Identity=27.1641791044776, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI87082277, Length=352, Percent_Identity=24.1477272727273, Blast_Score=65, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574683, Length=214, Percent_Identity=28.9719626168224, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28574681, Length=214, Percent_Identity=28.9719626168224, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28574685, Length=214, Percent_Identity=28.9719626168224, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28574678, Length=214, Percent_Identity=28.9719626168224, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24581759, Length=184, Percent_Identity=31.5217391304348, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19920704, Length=184, Percent_Identity=31.5217391304348, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000802
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 43114; Mature: 43114

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTGIILGLTLFVFAVGKSPVFRIDRAGAAIIGATATIAAGALSFDQAAQAIDHRTLVL
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHH
LFSMMIISANLKLGGFFEKTGDFLLRAASSRRQLLMVIVMMSGLLSALCINDIVCLLLTP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLTVCRRSGAPPLPHLLGVAMASNIGSAATLVGNPQNILIASISGMSFISYFLMAAPVA
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
VVSLFVTYIVIAFIFRKHLEGRLEHGETESTEYNSYVVGKSLLALTLVLTGFLLSLDMAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TASIGAAYLLITRRVSPNRVYESVDFNLLVIFTGLFVIVGGVEHTGLMKWLIGKSPFIDF
HHHHHHEEEHEEECCCHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
GNLAVFGAATVVLSNIFSNVPAVMLLKYFMPQQSSDVWWTALAIFSTIAGNLTITGSIAN
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHH
LIVAEIAKGERIRIGFWDYFKAGFPLTVVVSALSMLILWQIS
HHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MITTGIILGLTLFVFAVGKSPVFRIDRAGAAIIGATATIAAGALSFDQAAQAIDHRTLVL
CCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHHHHHHHCCHHHHHHHHHHHHHHH
LFSMMIISANLKLGGFFEKTGDFLLRAASSRRQLLMVIVMMSGLLSALCINDIVCLLLTP
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVLTVCRRSGAPPLPHLLGVAMASNIGSAATLVGNPQNILIASISGMSFISYFLMAAPVA
HHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCHHHHHHHHHHHHHHH
VVSLFVTYIVIAFIFRKHLEGRLEHGETESTEYNSYVVGKSLLALTLVLTGFLLSLDMAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TASIGAAYLLITRRVSPNRVYESVDFNLLVIFTGLFVIVGGVEHTGLMKWLIGKSPFIDF
HHHHHHEEEHEEECCCHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCC
GNLAVFGAATVVLSNIFSNVPAVMLLKYFMPQQSSDVWWTALAIFSTIAGNLTITGSIAN
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEHHHHH
LIVAEIAKGERIRIGFWDYFKAGFPLTVVVSALSMLILWQIS
HHHHHHCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]