Click here to switch to the map view.

The map label for this gene is yqeV [H]

Identifier: 85860140

GI number: 85860140

Start: 2346685

End: 2348040

Strand: Direct

Name: yqeV [H]

Synonym: SYN_00797

Alternate gene names: 85860140

Gene position: 2346685-2348040 (Clockwise)

Preceding gene: 85860139

Following gene: 85860141

Centisome position: 73.81

GC content: 58.04

Gene sequence:

>1356_bases
ATGACCGGGTTATTGGAGGAGGATGGATTGAACAGGGAATCCCTCTCGATTAAGGCAGCGATCGCCACACTGGGATGCAA
AGTCAACCAGTATGAATCGGAGGGTCTCGGGGAGGCCCTCACCAGAAGGGGCTACACGATGGTTCCCTTCTCCTCGGTAG
CGGACTGCTACATCATCAACACGTGCACCGTTACGGCCAGGACCAATTATCAGTCCCGGCAGATTATCCGAAAGGCGATT
CGGAATAACCCGGAAGCCGTCATTGTTGTAACGGGGTGCTACGCCCAGACCGCCCCCGCGGAAATCGCCGGAATTCCTGG
AGTCACCCTCATTGCCGGACACGCGGAAAAAGATCAGATTCCCGATCTGATTGCCCGCCTGCTGAAAGAACGGCTGGAAA
TCCGGGTTGGAGACATCGGGCAGACCCGGCAATTCTCTTCCCTGGCGGCGACCCGTTTTAAGGACCATACCCGGGCCTTT
CTGAAAATTCAGGACGGCTGCAATGCCTGGTGCAGCTACTGCATCATCCCATCCGCCCGGGGAAGAAGCCGGAGCCTCGC
GGAAGGCAGCGTCCTGGAGCAGCTCGCCCACATGGGCCGGACCGGCTACCGGGAGGTCGTTCTTACGGGAATTCACCTCG
GCGCCTATGGACAGGATTTTTCTCCGCAGTCCTCCCTCGTCGATCTCCTGAGAAAAGTGGAGGAACAGCATCCTGTGGAG
CGGCTCCGCCTGAGCTCCATCGAGCCAACGGAGATTTCAGACGACTTCATCGCCCTGCTGCGGCAATCCGCTCTGCTCTG
TCCGCACCTGCACATCCCGCTCCAGAGTGGCGATGACTCCATTCTGACTCGCATGAAGCGGCATTACACAACCTCTTTCT
TCAAGGACCTGCTTGAAAAGCTTTGCCGGGCGATCCCGGATCTGGCGATCGGCATCGACGTGATTGCCGGTTTTCCCGGA
GAAGGCGAGGCTGCTTTTGAGCGCACGGTCGAGCTCATCGAGTCCCTTCCCGTGGCCTATCTTCATGTCTTTCCCTATTC
AGTGCGTCCAGGCACCCCGGCCGCCGCCATGCCGGACCAGGTCTCCCCGGACGAGAAGAAAAAGCGTGCGGAAATTCTTC
GAACGCTGGGAACCCGCAAAAGGGAAGCCTTCGCCCGACGGTTTCACGGCCGCAGCCTGCGTGTTCTTGTGGAGGAGCGC
AGAGAGCGGAGCAGTGGCCTGAGAAAAGGATTTTCCGGCAATTACCTACCCATTCTCATGACCAATGCCGACGCCTCGCA
GGTCAATCAACTGGTGCAGGTCCAGATTGAAAACATCGATGGCACAAGAATTTCTGGAAGGATCATGACCCCATGA

Upstream 100 bases:

>100_bases
CGGCCGGCCGATCATGAAGAAGCCGGAGACAAGCTGATAATCCGCTTTCAGGAACCTCAGCGGGCTGTCGCACCGGGCCA
GGCCGCCGTATTCTATTCCG

Downstream 100 bases:

>100_bases
CGGAAGAACGACAAACGGCCCTGAAGAAACTGGAATCACATCTTTCCTGTGCGTTCCGCGACATCACTCTGCTTGATAAC
GCCCTGGTCCATCGCTCCTA

Product: tRNA 2-methylthioadenosine synthase -like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTGLLEEDGLNRESLSIKAAIATLGCKVNQYESEGLGEALTRRGYTMVPFSSVADCYIINTCTVTARTNYQSRQIIRKAI
RNNPEAVIVVTGCYAQTAPAEIAGIPGVTLIAGHAEKDQIPDLIARLLKERLEIRVGDIGQTRQFSSLAATRFKDHTRAF
LKIQDGCNAWCSYCIIPSARGRSRSLAEGSVLEQLAHMGRTGYREVVLTGIHLGAYGQDFSPQSSLVDLLRKVEEQHPVE
RLRLSSIEPTEISDDFIALLRQSALLCPHLHIPLQSGDDSILTRMKRHYTTSFFKDLLEKLCRAIPDLAIGIDVIAGFPG
EGEAAFERTVELIESLPVAYLHVFPYSVRPGTPAAAMPDQVSPDEKKKRAEILRTLGTRKREAFARRFHGRSLRVLVEER
RERSSGLRKGFSGNYLPILMTNADASQVNQLVQVQIENIDGTRISGRIMTP

Sequences:

>Translated_451_residues
MTGLLEEDGLNRESLSIKAAIATLGCKVNQYESEGLGEALTRRGYTMVPFSSVADCYIINTCTVTARTNYQSRQIIRKAI
RNNPEAVIVVTGCYAQTAPAEIAGIPGVTLIAGHAEKDQIPDLIARLLKERLEIRVGDIGQTRQFSSLAATRFKDHTRAF
LKIQDGCNAWCSYCIIPSARGRSRSLAEGSVLEQLAHMGRTGYREVVLTGIHLGAYGQDFSPQSSLVDLLRKVEEQHPVE
RLRLSSIEPTEISDDFIALLRQSALLCPHLHIPLQSGDDSILTRMKRHYTTSFFKDLLEKLCRAIPDLAIGIDVIAGFPG
EGEAAFERTVELIESLPVAYLHVFPYSVRPGTPAAAMPDQVSPDEKKKRAEILRTLGTRKREAFARRFHGRSLRVLVEER
RERSSGLRKGFSGNYLPILMTNADASQVNQLVQVQIENIDGTRISGRIMTP
>Mature_450_residues
TGLLEEDGLNRESLSIKAAIATLGCKVNQYESEGLGEALTRRGYTMVPFSSVADCYIINTCTVTARTNYQSRQIIRKAIR
NNPEAVIVVTGCYAQTAPAEIAGIPGVTLIAGHAEKDQIPDLIARLLKERLEIRVGDIGQTRQFSSLAATRFKDHTRAFL
KIQDGCNAWCSYCIIPSARGRSRSLAEGSVLEQLAHMGRTGYREVVLTGIHLGAYGQDFSPQSSLVDLLRKVEEQHPVER
LRLSSIEPTEISDDFIALLRQSALLCPHLHIPLQSGDDSILTRMKRHYTTSFFKDLLEKLCRAIPDLAIGIDVIAGFPGE
GEAAFERTVELIESLPVAYLHVFPYSVRPGTPAAAMPDQVSPDEKKKRAEILRTLGTRKREAFARRFHGRSLRVLVEERR
ERSSGLRKGFSGNYLPILMTNADASQVNQLVQVQIENIDGTRISGRIMTP

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=391, Percent_Identity=31.2020460358056, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI28872784, Length=456, Percent_Identity=26.0964912280702, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI28872782, Length=456, Percent_Identity=26.0964912280702, Blast_Score=138, Evalue=1e-32,
Organism=Escherichia coli, GI1786882, Length=442, Percent_Identity=31.2217194570136, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1787057, Length=401, Percent_Identity=27.1820448877805, Blast_Score=132, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17553146, Length=452, Percent_Identity=27.4336283185841, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71996771, Length=314, Percent_Identity=30.8917197452229, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21356207, Length=432, Percent_Identity=24.7685185185185, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI19922432, Length=441, Percent_Identity=30.3854875283447, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 49973; Mature: 49842

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS50926 TRAM ; PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLLEEDGLNRESLSIKAAIATLGCKVNQYESEGLGEALTRRGYTMVPFSSVADCYIIN
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHCCCEECCHHHCCCEEEEE
TCTVTARTNYQSRQIIRKAIRNNPEAVIVVTGCYAQTAPAEIAGIPGVTLIAGHAEKDQI
EEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCCEEEEECCCCCCHH
PDLIARLLKERLEIRVGDIGQTRQFSSLAATRFKDHTRAFLKIQDGCNAWCSYCIIPSAR
HHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHCCCCCC
GRSRSLAEGSVLEQLAHMGRTGYREVVLTGIHLGAYGQDFSPQSSLVDLLRKVEEQHPVE
CCCCCCCCHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHH
RLRLSSIEPTEISDDFIALLRQSALLCPHLHIPLQSGDDSILTRMKRHYTTSFFKDLLEK
HHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LCRAIPDLAIGIDVIAGFPGEGEAAFERTVELIESLPVAYLHVFPYSVRPGTPAAAMPDQ
HHHHCCCHHCCHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCCCCC
VSPDEKKKRAEILRTLGTRKREAFARRFHGRSLRVLVEERRERSSGLRKGFSGNYLPILM
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TNADASQVNQLVQVQIENIDGTRISGRIMTP
ECCCHHHHHHHHHEEEECCCCCEECCEEECC
>Mature Secondary Structure 
TGLLEEDGLNRESLSIKAAIATLGCKVNQYESEGLGEALTRRGYTMVPFSSVADCYIIN
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHCCHHHHHHHCCCEECCHHHCCCEEEEE
TCTVTARTNYQSRQIIRKAIRNNPEAVIVVTGCYAQTAPAEIAGIPGVTLIAGHAEKDQI
EEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHCCCCCEEEEECCCCCCHH
PDLIARLLKERLEIRVGDIGQTRQFSSLAATRFKDHTRAFLKIQDGCNAWCSYCIIPSAR
HHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHCCCCCC
GRSRSLAEGSVLEQLAHMGRTGYREVVLTGIHLGAYGQDFSPQSSLVDLLRKVEEQHPVE
CCCCCCCCHHHHHHHHHCCCCCCHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHH
RLRLSSIEPTEISDDFIALLRQSALLCPHLHIPLQSGDDSILTRMKRHYTTSFFKDLLEK
HHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
LCRAIPDLAIGIDVIAGFPGEGEAAFERTVELIESLPVAYLHVFPYSVRPGTPAAAMPDQ
HHHHCCCHHCCHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCCCCCCC
VSPDEKKKRAEILRTLGTRKREAFARRFHGRSLRVLVEERRERSSGLRKGFSGNYLPILM
CCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
TNADASQVNQLVQVQIENIDGTRISGRIMTP
ECCCHHHHHHHHHEEEECCCCCEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]