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The map label for this gene is 85860006

Identifier: 85860006

GI number: 85860006

Start: 2223541

End: 2224593

Strand: Direct

Name: 85860006

Synonym: SYN_00740

Alternate gene names: NA

Gene position: 2223541-2224593 (Clockwise)

Preceding gene: 85860004

Following gene: 85860011

Centisome position: 69.94

GC content: 54.13

Gene sequence:

>1053_bases
ATGAAGAAGACGGGCGTTGTTAAAGACGAAAGGTATATGAATCATCTTACCGGACCGGGACACCCGGAAAGTCCGCGGCG
GCTTGAAGTCATCTATGACATGCTCGAAGACCGTGATATGCAGGGACGCTTTCAGGACGTACCGGCCAGGGAGGCCAGGA
TGGATGAGCTTCATCTCATCCATTTGCCGGATTATGTGAACAGAGTCGCATCAACCGCAAGGATGGAATACAGCTGTCTG
GATCCGGACACGGACACTTCTCCCGGATCCTATAAAGCGGCTCTGCTGGCCGCCGGAGGGCTATGCGAGGCCATCTCCAT
GGTGGCGTCCGGAAAACTGGACAATGCTTTTGCACTGGTGCGACCACCGGGTCATCATGCCGAGGCCGACAGGAGCAAAG
GGTTCTGCCTGTTCAACAATGTGGCCATTGGCGCCCGATATGCCCAGACAGCACTTCATCTCCAGCGGATACTGATCATT
GACTGGGATCTTCATCACGGAAACGGCACCCAGCATTCTTTTGAAACGGATCCATCCATCCTCTATTTTTCAACCCACCA
ATACCCTTATTTTCCGGGAACCGGGGCCTGTGATGAAGTGGGAAGGCGGACGGGCCTCGGATTTACGGTAAATGTACCAC
TGAGCAGAGGATACGGTGACGGAGAATATGCGGCCATTTTCGAGAAGATTCTTAAATCCATCGCACCGGAATTCAGCCCC
GATCTGATCCTGGTATCCGCCGGCTTTGATATCTACGGAGGAGATCCGCTGGGCGGAATGAGGGTTTCCCCGAAGGGATT
TGCCGGGCTGACCCGTTTAATCGTGGATATCGCCGTATCCTGCTGCAGCGGCAAGGTCGTCCTGACCCTTGAAGGAGGTT
ATGATCTGACCGGTCTGAGAGACAGTGTAAAGGCTGTTCTGAAGGAACTGGCCGGACTGTCACACACAGATTATGCCGAT
ATGGCGTTGCAGGCCAACCAGGCGGCCGTCGACAGGGCATTGAAACCTGTTCTTCAGGTGAACAGAAATTACTGGAAGGG
CCTGACACCTTGA

Upstream 100 bases:

>100_bases
GAAAAAGGGGAAGCCCCATTCACCGGAAAACCGAAAAAATTGTACGCGGCCGATCAATTTCAACATTTGCAATCCATAGA
CCTGCAGATGGGAGAGGAAC

Downstream 100 bases:

>100_bases
CAGCCGCAATTCCCCTTTCCTGGCACCCCGGCGTTTTTCTGAACCGGGGAAGGCCGGTTAATTCCCTGGGGATTTTCTGA
TTTCCCGGATCAGGCGGCGC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKKTGVVKDERYMNHLTGPGHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLIHLPDYVNRVASTARMEYSCL
DPDTDTSPGSYKAALLAAGGLCEAISMVASGKLDNAFALVRPPGHHAEADRSKGFCLFNNVAIGARYAQTALHLQRILII
DWDLHHGNGTQHSFETDPSILYFSTHQYPYFPGTGACDEVGRRTGLGFTVNVPLSRGYGDGEYAAIFEKILKSIAPEFSP
DLILVSAGFDIYGGDPLGGMRVSPKGFAGLTRLIVDIAVSCCSGKVVLTLEGGYDLTGLRDSVKAVLKELAGLSHTDYAD
MALQANQAAVDRALKPVLQVNRNYWKGLTP

Sequences:

>Translated_350_residues
MKKTGVVKDERYMNHLTGPGHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLIHLPDYVNRVASTARMEYSCL
DPDTDTSPGSYKAALLAAGGLCEAISMVASGKLDNAFALVRPPGHHAEADRSKGFCLFNNVAIGARYAQTALHLQRILII
DWDLHHGNGTQHSFETDPSILYFSTHQYPYFPGTGACDEVGRRTGLGFTVNVPLSRGYGDGEYAAIFEKILKSIAPEFSP
DLILVSAGFDIYGGDPLGGMRVSPKGFAGLTRLIVDIAVSCCSGKVVLTLEGGYDLTGLRDSVKAVLKELAGLSHTDYAD
MALQANQAAVDRALKPVLQVNRNYWKGLTP
>Mature_350_residues
MKKTGVVKDERYMNHLTGPGHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLIHLPDYVNRVASTARMEYSCL
DPDTDTSPGSYKAALLAAGGLCEAISMVASGKLDNAFALVRPPGHHAEADRSKGFCLFNNVAIGARYAQTALHLQRILII
DWDLHHGNGTQHSFETDPSILYFSTHQYPYFPGTGACDEVGRRTGLGFTVNVPLSRGYGDGEYAAIFEKILKSIAPEFSP
DLILVSAGFDIYGGDPLGGMRVSPKGFAGLTRLIVDIAVSCCSGKVVLTLEGGYDLTGLRDSVKAVLKELAGLSHTDYAD
MALQANQAAVDRALKPVLQVNRNYWKGLTP

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=362, Percent_Identity=42.2651933701657, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI153085395, Length=382, Percent_Identity=38.2198952879581, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI30795202, Length=384, Percent_Identity=37.5, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI30795204, Length=384, Percent_Identity=37.5, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI20070354, Length=303, Percent_Identity=43.8943894389439, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI17158039, Length=347, Percent_Identity=39.4812680115274, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI148539870, Length=384, Percent_Identity=38.8020833333333, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI169234807, Length=384, Percent_Identity=38.8020833333333, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI62750347, Length=382, Percent_Identity=37.696335078534, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI62750349, Length=382, Percent_Identity=37.696335078534, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI226529806, Length=303, Percent_Identity=39.6039603960396, Blast_Score=196, Evalue=2e-50,
Organism=Homo sapiens, GI13128860, Length=272, Percent_Identity=27.9411764705882, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI8923769, Length=283, Percent_Identity=26.1484098939929, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI293336691, Length=273, Percent_Identity=26.3736263736264, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI13128862, Length=266, Percent_Identity=27.4436090225564, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI262073088, Length=193, Percent_Identity=31.6062176165803, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI209862883, Length=276, Percent_Identity=25.3623188405797, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI262073092, Length=216, Percent_Identity=26.8518518518519, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI217272877, Length=297, Percent_Identity=24.9158249158249, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193209491, Length=384, Percent_Identity=37.5, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17540334, Length=360, Percent_Identity=33.6111111111111, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI193206283, Length=360, Percent_Identity=33.6111111111111, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17540332, Length=360, Percent_Identity=33.6111111111111, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17537347, Length=330, Percent_Identity=36.3636363636364, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI25154020, Length=321, Percent_Identity=33.3333333333333, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI25154022, Length=321, Percent_Identity=33.0218068535826, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17508561, Length=272, Percent_Identity=27.9411764705882, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17561978, Length=283, Percent_Identity=25.4416961130742, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17534739, Length=287, Percent_Identity=27.1777003484321, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324307, Length=352, Percent_Identity=34.6590909090909, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6323999, Length=279, Percent_Identity=27.9569892473118, Blast_Score=124, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321244, Length=271, Percent_Identity=28.7822878228782, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325325, Length=203, Percent_Identity=29.064039408867, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325141, Length=287, Percent_Identity=24.390243902439, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24642146, Length=353, Percent_Identity=40.2266288951841, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24642144, Length=353, Percent_Identity=40.2266288951841, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24642142, Length=353, Percent_Identity=40.2266288951841, Blast_Score=244, Evalue=6e-65,
Organism=Drosophila melanogaster, GI281360899, Length=353, Percent_Identity=40.2266288951841, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI281360799, Length=378, Percent_Identity=37.8306878306878, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI24641720, Length=378, Percent_Identity=37.8306878306878, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI281360801, Length=378, Percent_Identity=37.8306878306878, Blast_Score=224, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24657891, Length=275, Percent_Identity=29.0909090909091, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24644244, Length=283, Percent_Identity=26.8551236749117, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24649807, Length=251, Percent_Identity=27.0916334661355, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 38232; Mature: 38232

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTGVVKDERYMNHLTGPGHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLI
CCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCHHHCCCCEEEE
HLPDYVNRVASTARMEYSCLDPDTDTSPGSYKAALLAAGGLCEAISMVASGKLDNAFALV
ECCHHHHHHHHHHHCEEEECCCCCCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCCCEEEE
RPPGHHAEADRSKGFCLFNNVAIGARYAQTALHLQRILIIDWDLHHGNGTQHSFETDPSI
CCCCCCCCCCCCCCEEEEECEEHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCCCCCCE
LYFSTHQYPYFPGTGACDEVGRRTGLGFTVNVPLSRGYGDGEYAAIFEKILKSIAPEFSP
EEEECCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DLILVSAGFDIYGGDPLGGMRVSPKGFAGLTRLIVDIAVSCCSGKVVLTLEGGYDLTGLR
CEEEEECCCEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
DSVKAVLKELAGLSHTDYADMALQANQAAVDRALKPVLQVNRNYWKGLTP
HHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCHHHCCCCCC
>Mature Secondary Structure
MKKTGVVKDERYMNHLTGPGHPESPRRLEVIYDMLEDRDMQGRFQDVPAREARMDELHLI
CCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCHHHCCCCEEEE
HLPDYVNRVASTARMEYSCLDPDTDTSPGSYKAALLAAGGLCEAISMVASGKLDNAFALV
ECCHHHHHHHHHHHCEEEECCCCCCCCCCCCEEHHHHCCCHHHHHHHHHCCCCCCCEEEE
RPPGHHAEADRSKGFCLFNNVAIGARYAQTALHLQRILIIDWDLHHGNGTQHSFETDPSI
CCCCCCCCCCCCCCEEEEECEEHHHHHHHHHHHHEEEEEEEEEEECCCCCCCCCCCCCCE
LYFSTHQYPYFPGTGACDEVGRRTGLGFTVNVPLSRGYGDGEYAAIFEKILKSIAPEFSP
EEEECCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
DLILVSAGFDIYGGDPLGGMRVSPKGFAGLTRLIVDIAVSCCSGKVVLTLEGGYDLTGLR
CEEEEECCCEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHH
DSVKAVLKELAGLSHTDYADMALQANQAAVDRALKPVLQVNRNYWKGLTP
HHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]