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The map label for this gene is dtd

Identifier: 85859453

GI number: 85859453

Start: 1659062

End: 1659511

Strand: Direct

Name: dtd

Synonym: SYN_00899

Alternate gene names: 85859453

Gene position: 1659062-1659511 (Clockwise)

Preceding gene: 85859452

Following gene: 85859455

Centisome position: 52.18

GC content: 44.67

Gene sequence:

>450_bases
GTGAGGGCGGTTGTTCAACGAGTCGATAAAGCCATTGTTAAAGTAAATGATCGGATTGTTTCCGATATTTCAAAGGGGAT
GCTTGTTTTCCTCGGCATCGAGAAGGGGGATGACTTCTCCGATGCGGATTTCCTTCTGGAGAAAGTGATTAATTTAAGAA
TCTTCGAAGATGAAGAGGGAAAGATGAACCGTTCTTTGTCAGACATTTCCGGGGAAATGCTTGTCGTTTCGCAATTTACA
CTTCTTGGAGATTGCCGAAAGGGCAGGCGGCCATCCTTTACATCCGCGGAAGACCCGGAACGGTCAAATATTCTTTATTC
GCATTTCATTAATCAGGCATCGGAACGGATCCCTGTGGTCAAGTCAGGAATATTTCAGGCGATGATGAAGGTCAGTCTGG
TCAATGACGGACCGGTAACAATGCTTCTTGACAGTAAAAGGCTTTTTTAA

Upstream 100 bases:

>100_bases
CTGCATTCATGACAACATTAAAATCCTTCGGAGAAAATGCTTGAAGGCTGTTTTCATTATTGATAACATGCACCCCCATT
AAACTGGGAAGGACGGAAGC

Downstream 100 bases:

>100_bases
GAAAGAGAGGCTTTTATGACTGAGGATTTAAAAAATGAAATCCCTTCGATAGATATCAGGATAGACAAAGACGGTGTCTG
GTACTACAAAGGAAACGAAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MRAVVQRVDKAIVKVNDRIVSDISKGMLVFLGIEKGDDFSDADFLLEKVINLRIFEDEEGKMNRSLSDISGEMLVVSQFT
LLGDCRKGRRPSFTSAEDPERSNILYSHFINQASERIPVVKSGIFQAMMKVSLVNDGPVTMLLDSKRLF

Sequences:

>Translated_149_residues
MRAVVQRVDKAIVKVNDRIVSDISKGMLVFLGIEKGDDFSDADFLLEKVINLRIFEDEEGKMNRSLSDISGEMLVVSQFT
LLGDCRKGRRPSFTSAEDPERSNILYSHFINQASERIPVVKSGIFQAMMKVSLVNDGPVTMLLDSKRLF
>Mature_149_residues
MRAVVQRVDKAIVKVNDRIVSDISKGMLVFLGIEKGDDFSDADFLLEKVINLRIFEDEEGKMNRSLSDISGEMLVVSQFT
LLGDCRKGRRPSFTSAEDPERSNILYSHFINQASERIPVVKSGIFQAMMKVSLVNDGPVTMLLDSKRLF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=42.2818791946309, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1790320, Length=143, Percent_Identity=46.1538461538462, Blast_Score=134, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=38.255033557047, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=39.1891891891892, Blast_Score=105, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=40.8163265306122, Blast_Score=110, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_SYNAS (Q2LTS7)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_461656.1
- HSSP:   O66742
- ProteinModelPortal:   Q2LTS7
- SMR:   Q2LTS7
- STRING:   Q2LTS7
- GeneID:   3885015
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_00899
- NMPDR:   fig|56780.10.peg.1598
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q2LTS7
- ProtClustDB:   PRK05273
- BioCyc:   SACI56780:SYN_00899-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16774; Mature: 16774

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVVQRVDKAIVKVNDRIVSDISKGMLVFLGIEKGDDFSDADFLLEKVINLRIFEDEEG
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCEEEECCCC
KMNRSLSDISGEMLVVSQFTLLGDCRKGRRPSFTSAEDPERSNILYSHFINQASERIPVV
CHHCCHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
KSGIFQAMMKVSLVNDGPVTMLLDSKRLF
HHHHHHHHHHHHCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRAVVQRVDKAIVKVNDRIVSDISKGMLVFLGIEKGDDFSDADFLLEKVINLRIFEDEEG
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHCEEEECCCC
KMNRSLSDISGEMLVVSQFTLLGDCRKGRRPSFTSAEDPERSNILYSHFINQASERIPVV
CHHCCHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHH
KSGIFQAMMKVSLVNDGPVTMLLDSKRLF
HHHHHHHHHHHHCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA