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The map label for this gene is ppnK [H]

Identifier: 85859152

GI number: 85859152

Start: 1327019

End: 1327906

Strand: Direct

Name: ppnK [H]

Synonym: SYN_02863

Alternate gene names: 85859152

Gene position: 1327019-1327906 (Clockwise)

Preceding gene: 85859150

Following gene: 85859153

Centisome position: 41.74

GC content: 57.77

Gene sequence:

>888_bases
ATGCAGGGCGGAAAGCGGATTAAAAAAATCGGGATTATCGCCAATATTCGGAAGGAAAAGGCGCTGGGATGCGCCGCGGA
ACTGAAGGCCTGGCTGCTGGATCAGGGCATGGAGGTTTTCCTCGATGAGGAGATTGCCGGGGTTCTGGGGGAGCCCGGCG
GGATGAACCGGCGTTCCCTGGCCGCTCAGGCCGATCTGCTGATTGTTCTCGGAGGGGACGGCACCATGCTGAGAGCGGCG
CGTTCCGTCCGGGAATTCGACATTCCCATCGTGGGCATCAATCTCGGGGCCTTCGGCTACCTGACGGACATCAACCTCAA
CGAAATGTATCCCTCCCTGGAGCGGATACTTTGCGGGAATTACGCGACGGAAAAGCGGATGATGCTCGATATGGAGGTGA
TGCGAGGCGGGCGGATTCTCTGCGAGCACACCGTACTCAACGACGTGGTCATCAACCGGGGTAATCTTTCCCGGATCATC
GACATGGAGACCGCCGTCGACGACCATTATCTGACGACATTCCGGGCCGACGGGCTGATCATCAGCACCCCCACCGGTTC
GACGGCCTATTCGCTCTCCGCAGGAGGGCCGATCGTCTTTCCTTCCCAGGATGCCATCATCATTAATCCGATTTGTCCCC
ATACGCTGACCAACCGGCCTGTTATCCTGCCCTGCACAATGACCGTTTCCGTGAAGATCTGGTCGGAAGATGAAGGGGTG
AACGTCGACCTTGACGGACAGGAGTCCGTTGCGTTGAAATCGGGGGACATTCTGATCATCCGCCGATCCCGCTACATGAC
CACCCTGGTTTCTTCTCAGAACCGGGATTATCTCGAAATCCTGCGATCCAAACTGGGATGGGGCCGACTGCCCGCCATGA
ACCGATAA

Upstream 100 bases:

>100_bases
TTTGTCAAGAGGAATACCGGGACGGTACAATTATATCGTGGACACTGCGGGTTGTTTATGATACTTCAGTGCAGTTTTTT
CTCCATGAAGGAGCCGGGGG

Downstream 100 bases:

>100_bases
GCTCAGGATGCTGGCGCAACTCAAGATTCGCAACTTCGCCCTGATCGACGCCCTGGATGTATCCTTCGACCGGGGGCTGA
ATATTCTTTCCGGTGAAACC

Product: ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQGGKRIKKIGIIANIRKEKALGCAAELKAWLLDQGMEVFLDEEIAGVLGEPGGMNRRSLAAQADLLIVLGGDGTMLRAA
RSVREFDIPIVGINLGAFGYLTDINLNEMYPSLERILCGNYATEKRMMLDMEVMRGGRILCEHTVLNDVVINRGNLSRII
DMETAVDDHYLTTFRADGLIISTPTGSTAYSLSAGGPIVFPSQDAIIINPICPHTLTNRPVILPCTMTVSVKIWSEDEGV
NVDLDGQESVALKSGDILIIRRSRYMTTLVSSQNRDYLEILRSKLGWGRLPAMNR

Sequences:

>Translated_295_residues
MQGGKRIKKIGIIANIRKEKALGCAAELKAWLLDQGMEVFLDEEIAGVLGEPGGMNRRSLAAQADLLIVLGGDGTMLRAA
RSVREFDIPIVGINLGAFGYLTDINLNEMYPSLERILCGNYATEKRMMLDMEVMRGGRILCEHTVLNDVVINRGNLSRII
DMETAVDDHYLTTFRADGLIISTPTGSTAYSLSAGGPIVFPSQDAIIINPICPHTLTNRPVILPCTMTVSVKIWSEDEGV
NVDLDGQESVALKSGDILIIRRSRYMTTLVSSQNRDYLEILRSKLGWGRLPAMNR
>Mature_295_residues
MQGGKRIKKIGIIANIRKEKALGCAAELKAWLLDQGMEVFLDEEIAGVLGEPGGMNRRSLAAQADLLIVLGGDGTMLRAA
RSVREFDIPIVGINLGAFGYLTDINLNEMYPSLERILCGNYATEKRMMLDMEVMRGGRILCEHTVLNDVVINRGNLSRII
DMETAVDDHYLTTFRADGLIISTPTGSTAYSLSAGGPIVFPSQDAIIINPICPHTLTNRPVILPCTMTVSVKIWSEDEGV
NVDLDGQESVALKSGDILIIRRSRYMTTLVSSQNRDYLEILRSKLGWGRLPAMNR

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=331, Percent_Identity=30.2114803625378, Blast_Score=122, Evalue=4e-28,
Organism=Escherichia coli, GI1788968, Length=297, Percent_Identity=37.037037037037, Blast_Score=205, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71999610, Length=184, Percent_Identity=29.3478260869565, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320794, Length=240, Percent_Identity=38.75, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=33.75, Blast_Score=143, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6325068, Length=212, Percent_Identity=32.0754716981132, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=31.2252964426877, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=31.2252964426877, Blast_Score=110, Evalue=8e-25,
Organism=Drosophila melanogaster, GI28573830, Length=253, Percent_Identity=31.2252964426877, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI28573832, Length=253, Percent_Identity=31.2252964426877, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28573826, Length=253, Percent_Identity=31.2252964426877, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=29.136690647482, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=29.136690647482, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=29.136690647482, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=29.136690647482, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=29.136690647482, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32424; Mature: 32424

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGGKRIKKIGIIANIRKEKALGCAAELKAWLLDQGMEVFLDEEIAGVLGEPGGMNRRSL
CCCCCEEEEEEEEEECCHHHHCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCHHHH
AAQADLLIVLGGDGTMLRAARSVREFDIPIVGINLGAFGYLTDINLNEMYPSLERILCGN
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHCCC
YATEKRMMLDMEVMRGGRILCEHTVLNDVVINRGNLSRIIDMETAVDDHYLTTFRADGLI
CCCCHHHEEEHHHHCCCEEEEEEEEHHHEEECCCCCEEEEEEHHHCCCCEEEEEECCCEE
ISTPTGSTAYSLSAGGPIVFPSQDAIIINPICPHTLTNRPVILPCTMTVSVKIWSEDEGV
EECCCCCCEEEECCCCCEEECCCCCEEECCCCCCCCCCCCEEEEEEEEEEEEEECCCCCE
NVDLDGQESVALKSGDILIIRRSRYMTTLVSSQNRDYLEILRSKLGWGRLPAMNR
EEEECCCCCEEEECCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQGGKRIKKIGIIANIRKEKALGCAAELKAWLLDQGMEVFLDEEIAGVLGEPGGMNRRSL
CCCCCEEEEEEEEEECCHHHHCCHHHHHHHHHHHCCCEEEECCHHHHHCCCCCCCCHHHH
AAQADLLIVLGGDGTMLRAARSVREFDIPIVGINLGAFGYLTDINLNEMYPSLERILCGN
CCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHCCC
YATEKRMMLDMEVMRGGRILCEHTVLNDVVINRGNLSRIIDMETAVDDHYLTTFRADGLI
CCCCHHHEEEHHHHCCCEEEEEEEEHHHEEECCCCCEEEEEEHHHCCCCEEEEEECCCEE
ISTPTGSTAYSLSAGGPIVFPSQDAIIINPICPHTLTNRPVILPCTMTVSVKIWSEDEGV
EECCCCCCEEEECCCCCEEECCCCCEEECCCCCCCCCCCCEEEEEEEEEEEEEECCCCCE
NVDLDGQESVALKSGDILIIRRSRYMTTLVSSQNRDYLEILRSKLGWGRLPAMNR
EEEECCCCCEEEECCCEEEEECCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA